CN103122374A - 多态性检测用探针、多态性检测方法、药效判定方法以及多态性检测用试剂盒 - Google Patents

多态性检测用探针、多态性检测方法、药效判定方法以及多态性检测用试剂盒 Download PDF

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CN103122374A
CN103122374A CN201210391127.1A CN201210391127A CN103122374A CN 103122374 A CN103122374 A CN 103122374A CN 201210391127 A CN201210391127 A CN 201210391127A CN 103122374 A CN103122374 A CN 103122374A
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base
sequence
probe
polymorphism
oligonucleotide
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黑濑熏
小森真理子
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Arkray Inc
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Arkray Inc
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/107—Temperature of melting, i.e. Tm
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Microbiology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201210391127.1A 2011-10-03 2012-10-08 多态性检测用探针、多态性检测方法、药效判定方法以及多态性检测用试剂盒 Pending CN103122374A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2011-219336 2011-10-03
JP2011219336 2011-10-03
JP2012-190186 2012-08-30
JP2012190186A JP2013090622A (ja) 2011-10-03 2012-08-30 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット

Publications (1)

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CN103122374A true CN103122374A (zh) 2013-05-29

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CN201210391127.1A Pending CN103122374A (zh) 2011-10-03 2012-10-08 多态性检测用探针、多态性检测方法、药效判定方法以及多态性检测用试剂盒

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US (1) US20130084568A1 (ja)
EP (1) EP2578701A1 (ja)
JP (1) JP2013090622A (ja)
KR (1) KR20130036146A (ja)
CN (1) CN103122374A (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107267621A (zh) * 2017-07-05 2017-10-20 上海赛安生物医药科技股份有限公司 Mdr1基因多态性检测体系及其试剂盒
CN108004307A (zh) * 2017-10-25 2018-05-08 广州和康医疗技术有限公司 一种糖皮质激素疗效预测snp位点检测的方法及试剂盒
CN108603222A (zh) * 2016-02-09 2018-09-28 荣研化学株式会社 对目标核酸进行检测的方法及该方法中使用的核酸探针
CN109295192A (zh) * 2018-10-29 2019-02-01 湖南健基生物技术有限公司 一种检测人mdr1基因多态性的组合物、试剂盒、样品处理方法和应用
CN110643699A (zh) * 2019-10-16 2020-01-03 成都仕康美生物科技有限公司 一种环孢素a代谢基因检测试剂盒及其应用方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6460626B2 (ja) * 2013-11-11 2019-01-30 学校法人慶應義塾 プローブ作製方法、プローブセット、及び表現型決定遺伝子検出方法
US20200087719A1 (en) * 2017-04-13 2020-03-19 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Labeling of oligonucleotide probes by multiple-way ligation
CN110643698B (zh) * 2019-10-16 2020-12-11 成都仕康美生物科技有限公司 一种他克莫司代谢基因检测试剂盒及其应用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998673B2 (en) * 2000-03-29 2011-08-16 Lgc Limited Hybridisation beacon and method of rapid sequence detection and discrimination
JP3963422B2 (ja) 2000-08-03 2007-08-22 日鉄環境エンジニアリング株式会社 核酸の測定方法
JP4454366B2 (ja) 2004-03-31 2010-04-21 アークレイ株式会社 Ｍｄｒ１遺伝子の変異の検出法ならびにそのための核酸プローブおよびキット

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108603222A (zh) * 2016-02-09 2018-09-28 荣研化学株式会社 对目标核酸进行检测的方法及该方法中使用的核酸探针
CN108603222B (zh) * 2016-02-09 2021-09-24 荣研化学株式会社 对目标核酸进行检测的方法及该方法中使用的核酸探针
CN113832215A (zh) * 2016-02-09 2021-12-24 荣研化学株式会社 对目标核酸进行检测的方法
US11434533B2 (en) 2016-02-09 2022-09-06 Eiken Kagaku Kabushiki Kaisha Method for detecting target nucleic acid and nucleic acid probe used therein
CN113832215B (zh) * 2016-02-09 2024-02-06 荣研化学株式会社 对目标核酸进行检测的方法
CN107267621A (zh) * 2017-07-05 2017-10-20 上海赛安生物医药科技股份有限公司 Mdr1基因多态性检测体系及其试剂盒
CN108004307A (zh) * 2017-10-25 2018-05-08 广州和康医疗技术有限公司 一种糖皮质激素疗效预测snp位点检测的方法及试剂盒
CN109295192A (zh) * 2018-10-29 2019-02-01 湖南健基生物技术有限公司 一种检测人mdr1基因多态性的组合物、试剂盒、样品处理方法和应用
CN110643699A (zh) * 2019-10-16 2020-01-03 成都仕康美生物科技有限公司 一种环孢素a代谢基因检测试剂盒及其应用方法

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EP2578701A1 (en) 2013-04-10
US20130084568A1 (en) 2013-04-04
KR20130036146A (ko) 2013-04-11

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Application publication date: 20130529