CN103120788A - Medicine for treating epilepsy and preparation method thereof - Google Patents
Medicine for treating epilepsy and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating epilepsy and a preparation method thereof. The medicine is prepared by honey mixed with 25 medicinal materials comprising jackinthepulpit tuber, pinellia tuber, leech, antelope horn, gadfly, peach seed, ground beetle, earthworm, bombyx batryticatus, chlorite schist, scorpion, centipede, bile arisaema, salvia miltiorrhiza, turmeric root-tuber, notoginseng and the like; and the medicinal materials are decocted by water and extracted to be thick paste or are crushed into fine powder, and then mixed with the honey to prepare into capsules, granules or pills. The medicine provided by the invention has the effects of soothing the nerves and calming the mind, stopping endogenous wind and relieving convulsion, eliminating heat and resolving stasis, cooling blood and promoting blood circulation, strengthening the spleen and stomach and dissipating phlegm for resuscitation, can be used for treating various types of epilepsy, mania, insomnia and depression, and has broad market application prospect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine for the treatment of epileptics and preparation method thereof.
Background technology
Epileptics is a kind of clinical commonly encountered diseases, be mainly in child and middle-aged population, epileptics is to form in the clinical middle overwhelming majority day after tomorrow, there is traditional Chinese medical science scholar to think, due to internal organs such as liver, kidney, the heart, brains because deficiency and excess is held concurrently mutually, phlegm-fire is made a psychological attack, heart spirit confused by phlegm, and occur falling suddenly, lose consciousness, to spit out white foams and blood stasis after the symptom of oneself waking up, its cause of disease has following factor: in congenital parent, cerebral trauma, posteriority cerebral trauma, pathological changes brain injury, pharmaceutical chemistry brain injury, wind-cold damp pathogen are invaded due to body and feelings will hinders.
The Chinese medicine of existing treatment epileptics is more, also has their own characteristics each in treatment, but yet there are no the open report of the drug regimen of the described proportioning of the application.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of instant effect, medicine of the treatment epileptics that therapeutic effect is good and preparation method thereof.
technical scheme provided by the invention is a kind of medicine for the treatment of epileptics, mainly made by the raw material of following weight portion: 30～60 parts of Rhizoma Arisaematis, 30～60 parts of Rhizoma Pinelliae, 60～90 parts of Hirudos, 30～60 parts of Cornu Saigae Tataricae, 30～60 parts of Tabanuss, 60～90 parts, Semen Persicae, 60～90 parts of eupolyphaga, 60～90 parts of Pheretimas, 60～90 parts of Bombyx Batryticatus, 60～90 parts of Lapis Chloriti, 60～90 parts of Scorpios, 90～180 parts of Scolopendras, 60～90 parts of Arisaema Cum Bile, 60～90 parts of Radix Salviae Miltiorrhizaes, 60～90 parts of Radix Curcumaes, 30～60 parts, Radix Notoginseng, 60～90 parts of Rhizoma Zingiberiss, 30～60 parts of Radix Polygalaes, 60～90 parts of Rhizoma Anemones Altaicaes, 30～60 parts of bar halberds, 30～60 parts of Herba Cistanches, 30～60 parts of Herba Epimedii, 30～60 parts of Rhizoma Alismatis, 10～30 parts of Rhizoma Coptidis, 10～20 parts of Boraxs, 500～1000 parts of Mel.
Preferred weight part of each raw material is:
40 parts of Rhizoma Arisaematis, 40 parts of Rhizoma Pinelliae, 75 parts of Hirudos, 45 parts of Cornu Saigae Tataricae, 45 parts of Tabanuss, 75 parts, Semen Persicae, 75 parts of eupolyphaga, 75 parts of Pheretimas, 80 parts of Bombyx Batryticatus, 80 parts of Lapis Chloriti, 75 parts of Scorpios, 135 parts of Scolopendras, 80 parts of Arisaema Cum Bile, 80 parts of Radix Salviae Miltiorrhizaes, 80 parts of Radix Curcumaes, 50 parts, Radix Notoginseng, 70 parts of Rhizoma Zingiberiss, 45 parts of Radix Polygalaes, 75 parts of Rhizoma Anemones Altaicaes, 50 parts of halberds of bar, 50 parts of Herba Cistanches, 50 parts of Herba Epimedii, 45 parts of Rhizoma Alismatis, 20 parts of Rhizoma Coptidis, 15 parts of Boraxs, 750 parts of Mel.
The dosage form of said medicine can be medically acceptable any dosage form, is specially pill, granule or capsule.
The present invention also provides the preparation method of the medicine of above-mentioned treatment epileptics, comprises the following steps:
1) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio and the Borax of formula ratio are cleaned, dried, grind to form fine powder, standby;
2) Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and the Rhizoma Coptidis with formula ratio is placed in container, decoct with water 2 times, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 60～80 ℃ and are determined as 1.20～1.38 thick paste at 60 ℃;
3) with medicated powder and the step 2 of step 1)) thick paste and Mel mixing, make as required different preparations.
In the step 1) of said method, raw material is ground to 100～300 orders.
The step 2 of said method) in, in decocting with water process, the consumption of water is 8～12 times of weight of feeding intake for the first time, decocts 1～3 hour, and the consumption of water is 6～10 times of weight of feeding intake for the second time, decocts 1～3 hour.
In the step 3) of said method, the dosage form of described preparation can be medically acceptable any dosage form, is specially pill, granule or capsule.
In medicine of the present invention, the mechanism of each raw medicinal material is as follows:
Rhizoma Arisaematis, drying dampness to eliminate phlegm is expellingged wind and relieving convulsion, mass dissipating and swelling eliminating;
Rhizoma Pinelliae, acrid in the mouth, warm in nature, enter lung, spleen, stomach three warps, reducing swelling and alleviating pain;
Hirudo (Whitmania pigra Whitman), the master gathers by stagnant blood, blood stasis, removing blood stasis removing food stagnancy;
Scolopendra (Scolopendra subspinipes), warm in nature, acrid in the mouth, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain;
Cornu Saigae Tataricae, salty in the mouth, cold in nature is returned Liver Channel, heart channel, suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, removing pathogenic heat from blood and toxic substance from the body;
Tabanus (Tabanus) has another name called the gadfly, and acrid in the mouth, hardship, salty are cold in nature, enter Liver Channel, and removing blood stasis stimulates the menstrual flow, the removing blood stasis eliminating mass;
Semen Persicae, bitter in the mouth, sweet, property is flat, GUIXIN, liver, large intestine channel, blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma;
Eupolyphaga is called again eupolyphoge sinensis (ground beetle), and salty in the mouth, cold in nature is returned Liver Channel, lower blood stasis, eliminating mass abdominal mass;
Pheretima (Geosaurus) is the dry products of Lumbricus, and is cold in nature, salty in the mouth, heat clearing away arresting convulsion, collateral dredging, relieving asthma, diuresis;
Bombyx Batryticatus, salty in the mouth, flat, enter liver, lung, stomach warp, expelling wind to relieve convulsion, dissipating phlegm and resolving masses;
Lapis Chloriti, sweet in the mouth, salty, property is flat, the pendant expectorant therapeutic method to keep the adverse QI flowing downwards, checking hyperfunction of the liver for relieving convulsion;
Scorpio (Scorpio), acrid in the mouth, property are put down, and return Liver Channel, the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain;
Arisaema Cum Bile, bitter in the mouth is cold, little suffering, and is cool in nature, returns lung, liver, spleen channel, removing heat-phlegm, dispelling wind and relieving convulsion;
Radix Salviae Miltiorrhizae, bitter in the mouth, flat, slightly warm in nature enters the heart, Liver Channel, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind;
Radix Curcumae, acrid in the mouth, hardship, cold in nature, return liver, the heart, lung meridian, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice;
Radix Notoginseng, warm in nature, sweet in the mouth, little hardship are returned liver, stomach warp, hemostasis, loose blood, analgesic therapy;
Rhizoma Zingiberis, acrid in the mouth, hot in nature is returned spleen, stomach, the heart, lung meridian, and warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention;
Radix Polygalae, warm in nature, bitter in the mouth, suffering, are eliminated the phlegm, are subsided a swelling at the Fructus Alpiniae Oxyphyllae of calming the nerves;
Rhizoma Anemones Altaicae, acrid in the mouth, warm in nature, inducing resuscitation and resolving phlegm, refreshment and tranquilization;
The bar halberd, sweet in the mouth, suffering, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling;
Herba Cistanches has another name called Herba Cistanches (Desertliving Cistanche), sweet-salty, little sad, and slightly warm in nature enters kidney, large intestine, spleen, liver, urinary bladder channel, reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, hard masses softening and resolving;
Herba Epimedii, acrid in the mouth, sweet, warm in nature, return liver, kidney channel, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling;
Rhizoma Alismatis, sweet in the mouth, light, cold in nature, return kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen, expel the heat-evil treating stranguria;
Rhizoma Coptidis, bitter in the mouth, cold in nature, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, dredge the meridian passage;
Borax, sweet in the mouth, salty, cool in nature, attach to the lung and stomach meridians, external heat-clearing and toxic substances removing, detumescence, anticorrosion, removing heat from the lung and dissipating phlegm for oral administration;
Mel, main trusted subordinate's pathogen, all infantile convulsion, settling five organs various symptoms and signs of deficiency, QI invigorating invigorating middle warmer, analgesic antidotal and hundred medicines.
The instructions of taking of medicine of the present invention is: take the medicine that is equivalent to crude drug 6～18g weight every day, take minutes for 3 times, in ante cibum or to take effect half an hour after meal better, 30 days is a course for the treatment of, and most of patient takes 3 courses for the treatment of and can cure.
Medicine of the present invention is theoretical according to the Chinese traditional treatment epilepsy, employing restores menstrual flow and invigorates blood circulation, eliminate the phlegm relieve dizziness, high fever, infantile convulsions, epilepsy, etc., waking up the patient from unconsciousness by dissipating phlegm, mind tranquilizing and the heart calming principle make, have whole body and the many-sided opsonic action of central nervous system, can be used for treating all types of epilepticss, manic, insomnia, depression, market application foreground is wide.
The specific embodiment
The invention will be further described with specific embodiment for the below, but be not limited to these embodiment.
Embodiment 1
1) proportioning by embodiment 1 in following table 1 takes each raw material, and is standby;
2) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio, Borax are cleaned, dried, grind to form 100 order fine powders, standby;
3) Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and Rhizoma Coptidis are placed in container, decoct with water 2 times, in decocting with water process, the consumption of water is 8 times of weight of feeding intake for the first time, decocted 1 hour, the consumption of water is 6 times of weight of feeding intake for the second time, decocted 1 hour, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 60 ℃ and are determined as 1.20 thick paste at 60 ℃;
4) with step 2) medicated powder and thick paste and the Mel mixing of step 3), make according to a conventional method pill, after the assay was approved packing.
Embodiment 2
1) proportioning by embodiment 2 in following table 1 takes each raw material, and is standby;
2) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio, Borax are cleaned, dried, grind to form 300 order fine powders, standby;
3) with the clean container that is placed in of Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and Rhizoma Coptidis, decoct with water 2 times, in decocting with water process, the consumption of water is 12 times of weight of feeding intake for the first time, decocted 3 hours, the consumption of water is 10 times of weight of feeding intake for the second time, decocted 3 hours, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 80 ℃ and are determined as 1.38 thick paste at 60 ℃;
4) with step 2) medicated powder and thick paste and the Mel mixing of step 3), make according to a conventional method capsule, after the assay was approved packing.
Embodiment 3
1) proportioning by embodiment 3 in following table 1 takes each raw material, and is standby;
2) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio, Borax are cleaned, dried, grind to form 200 order fine powders, standby;
3) Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and Rhizoma Coptidis are cleaned, be placed in container, decoct with water 2 times, in decocting with water process, the consumption of water is 10 times of weight of feeding intake for the first time, decocted 2 hours, the consumption of water is 8 times of weight of feeding intake for the second time, decocted 2 hours, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 70 ℃ and are determined as 1.30 thick paste at 60 ℃;
4) with step 2) medicated powder and thick paste and the Mel mixing of step 3), granulation agent according to a conventional method, packing after the assay was approved.
Embodiment 4
1) proportioning by embodiment 4 in following table 1 takes each raw material, and is standby;
2) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio, Borax are cleaned, dried, grind to form 100 order fine powders, standby;
3) Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and Rhizoma Coptidis are cleaned, be placed in container, decoct with water 2 times, in decocting with water process, the consumption of water is 12 times of weight of feeding intake for the first time, decocted 1 hour, the consumption of water is 10 times of weight of feeding intake for the second time, decocted 1 hour, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 80 ℃ and are determined as 1.20 thick paste at 60 ℃;
4) with step 2) medicated powder and thick paste and the Mel mixing of step 3), make according to a conventional method pill, after the assay was approved packing.
Table 1
| Raw material (g) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
| Rhizoma Arisaematis | 30 | 60 | 40 | 30 |
| Rhizoma Pinelliae | 30 | 60 | 40 | 60 |
| Hirudo | 60 | 90 | 75 | 60 |
[0068]?
| Cornu Saigae Tataricae | 30 | 60 | 45 | 60 |
| Tabanus | 30 | 60 | 45 | 30 |
| Semen Persicae | 60 | 90 | 75 | 90 |
| Eupolyphaga | 60 | 90 | 75 | 60 |
| Pheretima | 60 | 90 | 75 | 90 |
| Bombyx Batryticatus | 60 | 90 | 80 | 60 |
| Lapis Chloriti | 60 | 90 | 80 | 90 |
| Scorpio | 60 | 90 | 75 | 60 |
| Scolopendra | 90 | 180 | 135 | 90 |
| Arisaema Cum Bile | 60 | 90 | 80 | 90 |
| Radix Salviae Miltiorrhizae | 60 | 90 | 80 | 60 |
| Radix Curcumae | 60 | 90 | 80 | 90 |
| Radix Notoginseng | 30 | 60 | 50 | 30 |
| Rhizoma Zingiberis | 60 | 90 | 70 | 90 |
| Radix Polygalae | 30 | 60 | 45 | 30 |
| Rhizoma Anemones Altaicae | 60 | 90 | 75 | 90 |
| The bar halberd | 30 | 60 | 50 | 30 |
| Herba Cistanches | 30 | 60 | 50 | 60 |
| Herba Epimedii | 30 | 60 | 50 | 30 |
| Rhizoma Alismatis | 30 | 60 | 45 | 60 |
| Rhizoma Coptidis | 10 | 30 | 20 | 10 |
| Borax | 10 | 20 | 15 | 20 |
| Mel | 500 | 1000 | 750 | 500 |
Use and the therapeutic effect of medicine of the present invention are described below in conjunction with concrete case.
Case 1: Chen, female, 20 years old, after cause was hit the right side brain by basketball before 4 years, often headache and dizzy, fell in a swoon even suddenly sometimes, spit out white foams, woke up again in about 20 minutes and to come, the rear malaise of waking up, recently the morbidity interval is shorter and shorter, basically had an attack of one's old illness 1 time in every 7 days, invalid through multi-treatment, take the medicine 3 months of the embodiment of the present invention 1 on April 15th, 2007, above-mentioned symptom all disappears, and follows up a case by regular visits to have no recurrence in 2 years.
Case 2: Zhang, man, 22 years old, cause was sent out a hyperpyrexia tic before 2 years after, often random the playing of extremity, often occur evening and batter, the phenomenon of spitting out white foams in dizziness headache in bed, sometimes with bloody sputum, the human body of waking up after 20 minutes is weak all over, outbreak in about 7～10 days once, the medicine of taking the embodiment of the present invention 2 on April 12nd, 2006 after 3 months patient's state of an illness steady, drug withdrawal is followed up a case by regular visits to and was had no recurrence in 2 years.
Case 3: hair certain, the female, 12 years old, often dizzy, intelligence descended because of after hyperpyrexia twitches in 2007, the symptom of falling suddenly, be unreasonable, spit out white foams often occurred, this symptom continues general 20 minutes, the descendant that wakes up easily feels general weakness, perspires.The medicine of taking the embodiment of the present invention 3 on March 7th, 2008 is after 1 month, transference cure, the recurrence of following up a case by regular visits to that so far there are no.
Case 4: willow, the female, 10 years old, the patient because occurring paroxysmal right side numb limbs and tense tendons after viral encephalitis, twitched before 3 years.Discontinuity paroxysm right side numb limbs and tense tendons over 3 years is twitched, cyanotic lips, and body of the tongue is dark violet, is diagnosed as localized epilepsy.Through integrative therapy, the state of an illness has no improvement, and dull expression occurs, and insomnia is nervous.The medicine of taking the embodiment of the present invention 4 in January, 2010 is after 1 month, and patient right side numb limbs and tense tendons alleviates, and twitches frequency and reduces, and without nervous, it is normal that sleep recovers.After continuing to take 2 months, the patient recovers normally, and limbs without twitching, are followed up a case by regular visits to the stable nothing recurrence of conditions of patients in 2 years without numb.
Case 5: Liu, the female, 11 years old, two hand-tight holding appearred before year a year and a half without reason, cyanotic lips, pale complexion is spat out white foams, and syncope was revived after 1～3 minute, as ordinary person.Seizure frequency once is increased to an outbreak in month for several times gradually by an outbreak in month.Begin to take the medicine of the embodiment of the present invention 1 in August, 2011, after two weeks, above-mentioned symptom all disappears, and for consolidating curative effect, continues to take 2 first quarter moons, follows up a case by regular visits to not recurrence.
Case 6: Zhao, the man, 36 years old, suffered from the epilepsy medical history 13 years, be the complexity epilepsy, the outbreak of psychomotor type, the outbreak cycle is the longest 14 months, and the shortest one month is several times, through the many-sided treatment of hospital, poor effect.Long-term taking phenytoin Sodium, clonazepam, but that symptom is failed is controlled.Because patient's course of disease is longer, the state of an illness is complicated, takes in a large number Western medicine and has caused very large side effect to patient body, so take the medicine of the embodiment of the present invention 3 since in August, 2010, irritated insomnia hour, sleep, diet is good, only in one month in the middle of petit mal once, continued to take 2 months, conditions of patients is steady, and not recurrence is followed up a case by regular visits to so far in drug withdrawal.
Case 7: Ma, the man, 48 years old, the patient had 8 years because the paroxysmal left limb is numb.Patient's dim complexion, dull expression, left limb is dumb, and self-induction is numb, insomnia, cardiopalmus.Successively take the multi-medicament treatment, the state of an illness has no improvement, and dull expression, and insomnia is nervous, and the trend of increasing the weight of is arranged in recent years.Be diagnosed as stagnation of QI abundant expectoration type epilepsy.Take medicine of the present invention after 1 month in January, 2012, patient's left limb numbness alleviates to some extent, twitches and reduces, insomnia, nervous sx↓.Continued to take 1 month, the patient recovers normally to have rosy cheeks, and limbs are twitched without numbness, drug withdrawal.The recurrence of following up a case by regular visits to that so far there are no.
Case 8: Pan, the man, 29 years old, the patient fell in a swoon after screaming suddenly before 5 years, and this phenomenon occurs after 3 months again, and orthocolosis clonicity is simultaneously twitched, attaches most importance to the right side, gnathospasma, cyanotic lips turns on eyeball, topples over to the left, and coolness of extremities is breathed irregular.Show effect over 5 years without certain rule, reduce in the length of one's sleep, overwork, flu generally all can be had an attack of one's old illness in the situations such as anger.Hospital diagnosis is epilepsy, once takes multiple antiepileptic poor effect, and increases the weight of gradually.The medicine of taking the embodiment of the present invention 4 in October, 2009 is after 1 month, and the conditions of patients reaction is good, and epilepsy is not shown effect.Continued to take 2 months, and though work is tired, do not bring out epilepsy, memory, reagency are clearly better before treating.Continue to take drug withdrawal after 3 months.Follow up a case by regular visits to and had no recurrence in 2 years.
Claims (7)
1. medicine for the treatment of epileptics, it is characterized in that: it is mainly made by the raw material of following weight portion: 30～60 parts of Rhizoma Arisaematis, 30～60 parts of Rhizoma Pinelliae, 60～90 parts of Hirudos, 30～60 parts of Cornu Saigae Tataricae, 30～60 parts of Tabanuss, 60～90 parts, Semen Persicae, 60～90 parts of eupolyphaga, 60～90 parts of Pheretimas, 60～90 parts of Bombyx Batryticatus, 60～90 parts of Lapis Chloriti, 60～90 parts of Scorpios, 90～180 parts of Scolopendras, 60～90 parts of Arisaema Cum Bile, 60～90 parts of Radix Salviae Miltiorrhizaes, 60～90 parts of Radix Curcumaes, 30～60 parts, Radix Notoginseng, 60～90 parts of Rhizoma Zingiberiss, 30～60 parts of Radix Polygalaes, 60～90 parts of Rhizoma Anemones Altaicaes, 30～60 parts of bar halberds, 30～60 parts of Herba Cistanches, 30～60 parts of Herba Epimedii, 30～60 parts of Rhizoma Alismatis, 10～30 parts of Rhizoma Coptidis, 10～20 parts of Boraxs, 500～1000 parts of Mel.
2. the medicine for the treatment of epileptics according to claim 1, it is characterized in that: the weight portion of each raw material is: 40 parts of Rhizoma Arisaematis, 40 parts of Rhizoma Pinelliae, 75 parts of Hirudos, 45 parts of Cornu Saigae Tataricae, 45 parts of Tabanuss, 75 parts, Semen Persicae, 75 parts of eupolyphaga, 75 parts of Pheretimas, 80 parts of Bombyx Batryticatus, 80 parts of Lapis Chloriti, 75 parts of Scorpios, 135 parts of Scolopendras, 80 parts of Arisaema Cum Bile, 80 parts of Radix Salviae Miltiorrhizaes, 80 parts of Radix Curcumaes, 50 parts, Radix Notoginseng, 70 parts of Rhizoma Zingiberiss, 45 parts of Radix Polygalaes, 75 parts of Rhizoma Anemones Altaicaes, 50 parts of halberds of bar, 50 parts of Herba Cistanches, 50 parts of Herba Epimedii, 45 parts of Rhizoma Alismatis, 20 parts of Rhizoma Coptidis, 15 parts of Boraxs, 750 parts of Mel.
3. the medicine for the treatment of epileptics according to claim 1, it is characterized in that: the dosage form of this medicine is pill, granule or capsule.
4. the preparation method of the medicine for the treatment of epileptics claimed in claim 1 is characterized in that: comprise the following steps:
1) Rhizoma Arisaematis, Rhizoma Pinelliae, Hirudo, Cornu Saigae Tataricae, Tabanus, Scolopendra, Scorpio, the Borax of formula ratio are cleaned, dried, grind to form fine powder, standby;
2) Semen Persicae, eupolyphaga, Pheretima, Bombyx Batryticatus, Lapis Chloriti, Arisaema Cum Bile, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Notoginseng, Rhizoma Zingiberis, Radix Polygalae, Rhizoma Anemones Altaicae, bar halberd, Herba Cistanches, Herba Epimedii, Rhizoma Alismatis and the Rhizoma Coptidis with formula ratio is placed in container, decoct with water 2 times, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density in 60～80 ℃ and are determined as 1.20～1.38 thick paste at 60 ℃;
3) with medicated powder and the step 2 of step 1)) thick paste and Mel mixing, make as required different preparations.
5. the preparation method of the medicine for the treatment of epileptics according to claim 4, is characterized in that: step 1) in, raw material is ground to 100～300 orders.
6. the preparation method of the medicine for the treatment of epileptics according to claim 4, it is characterized in that: step 2) in, in decocting with water process, the consumption of water is 8～12 times of weight of feeding intake for the first time, decocted 1～3 hour, the consumption of water is 6～10 times of weight of feeding intake for the second time, decocts 1～3 hour.
7. the preparation method of the medicine for the treatment of epileptics according to claim 4, it is characterized in that: in step 3), the dosage form of described preparation is pill, granule or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310035860.4A CN103120788B (en) | 2012-11-29 | 2013-01-30 | Medicine for treating epilepsy and preparation method thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104975020A CN102949697A (en) | 2012-11-29 | 2012-11-29 | Medicine for treating epilepsy and preparation method thereof |
| CN201210497502.0 | 2012-11-29 | ||
| CN201310035860.4A CN103120788B (en) | 2012-11-29 | 2013-01-30 | Medicine for treating epilepsy and preparation method thereof |
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| CN103120788A true CN103120788A (en) | 2013-05-29 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1994439A (en) * | 2006-12-13 | 2007-07-11 | 谷瑞起 | Medicament for treating epilepsy |
| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
-
2012
- 2012-11-29 CN CN2012104975020A patent/CN102949697A/en active Pending
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1994439A (en) * | 2006-12-13 | 2007-07-11 | 谷瑞起 | Medicament for treating epilepsy |
| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 朱欧鸰等: "单纯中药治疗癫痫病的研究进展", 《世界中西医结合杂志》, vol. 5, no. 3, 31 December 2010 (2010-12-31), pages 272 - 275 * |
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| Publication number | Publication date |
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| CN102949697A (en) | 2013-03-06 |
| CN103120788B (en) | 2014-04-30 |
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