CN103110858B - Anti-transport-stress medicament for goats and application thereof - Google Patents
Anti-transport-stress medicament for goats and application thereof Download PDFInfo
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- CN103110858B CN103110858B CN201310035921.7A CN201310035921A CN103110858B CN 103110858 B CN103110858 B CN 103110858B CN 201310035921 A CN201310035921 A CN 201310035921A CN 103110858 B CN103110858 B CN 103110858B
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Abstract
The invention belongs to the field of animal medicine and in particular relates to a medicament for treating transport stress of animals. A Chinese medicinal composition comprises perfoliote knotweed herb, bical skullcap root, tangerine peel, hawthorn, swordlike atractylodes rhizome, coloured malt, medicated leaven, honeysuckle flowers, lotus leaves, cortex moutan, radix paeoniae rubra and gardenia. When being used with levomisole, sodium selenite and iodised salt together, the Chinese medicinal composition has an obvious effect on treating a transparent stress response of goats and can normalize each serum index timely.
Description
Technical field
The invention belongs to animal medicine field, be particularly used for the treatment of animal transport stress medicine.
Background technology
It stress be a series of nonspecific general reaction that body is subject to intense stimulus or occurs during for tense situation.From evolution viewpoint, it is the important defensive reaction of preserving individual survival, therefore can be referred to as anxiety, pressure, stress or coercive again.Cause stress stimulation be called stressor, kind is a lot.Generally speaking, every various factors that can cause Animal diseases, all can relatively regard stressor as, sums up and can be divided into non-damage and damaging two large classes.
Abrasive have physics, chemistry and biostimulation factors such as wound, burn, poisoning, infection and parasitic infestation.Non-damage stress stressor mainly comprise that spirituality stimulates, as animal hives off, weans, drives, cropping or transportation.Because stress due to transportation claims that again animal transport stress syndrome, mainly refer to animal in transportation or arrive hyperpyrexia, cough, stream clear water nasal mucus to occur after destination or the symptom such as have loose bowels.About using the research of collaborative treatment of Chinese and western medicines goat transport stress syndrome, also rare report.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition, its transport stress therapeutic effect to goat is obvious.
For achieving the above object, technical scheme of the present invention is:
Chinese medicine composition, composed of the following components by weight: Herba Polygoni cymosi 10-12 part, Radix Scutellariae 10-12 part, Pericarpium Citri Reticulatae 10-12 part, Fructus Crataegi 8-10 part, Rhizoma Atractylodis 8-10 part, Fructus Hordei Germinatus (parched) 6-8 part, six bent 6-8 parts, Flos Lonicerae 4-6 part, Folium Nelumbinis 4-6 part, Cortex Moutan 4-6 part, Radix Paeoniae Rubra 3-5 part, Fructus Gardeniae 3-5 part.
Further, described Chinese medicine composition, composed of the following components by weight: 10 parts of Herba Polygoni cymosis, 11 parts of Radix Scutellariaes, 12 parts of Pericarpium Citri Reticulataes, 9 parts of Fructus Crataegis, 9 parts of Rhizoma Atractylodis, 7 parts of Fructus Hordei Germinatus (parched)s, six 7 parts of songs, 5 parts of Flos Loniceraes, 5 parts, Folium Nelumbinis, 5 parts of Cortex Moutans, 4 parts of Radix Paeoniae Rubra, 4 parts of Fructus Gardeniaes.
Two of object of the present invention is to provide the application of above-mentioned composition, and this has applied animal transport stress provide treatment thinking by syndrome.
For achieving the above object, technical scheme of the present invention is:
The application of described Chinese medicine composition in the anti-transport stress medicine of preparation mammal.
Further, described mammal is goat.
Three of object of the present invention is the anti-transport stress medicine of goat, and it is the compositions of Chinese medicine and western medicine combination, and toxicity is low, effective.
For achieving the above object, technical scheme of the present invention is:
The anti-transport stress medicine of goat of described Chinese medicine composition, composed of the following components by weight:
Further, the anti-transport stress medicine of the goat of described Chinese medicine composition, composed of the following components by weight:
Four of object of the present invention is to provide the preparation method of said medicine, and the method is simple to operate, is applicable to large-scale production.
For achieving the above object, technical scheme of the present invention is:
The preparation method of the anti-transport stress medicine of described goat, specifically comprises the following steps:
The preparation of A Chinese medicine additive
Each component in described Chinese medicine composition is fully pulverized by formula ratio, and mixed, obtain Chinese medicine additive;
The preparation of the anti-transport stress medicine of B goat
Electrolysis multidimensional, levamisole, sodium selenite and the iodine salt of formula ratio are fully mixed with described Chinese medicine additive, obtain the anti-transport stress medicine of goat.
Four of object of the present invention is to provide a kind of feed additive, and it can treat goat transport stress syndrome, and free from extraneous odour.
For achieving the above object, technical scheme of the present invention is:
The feed additive of the anti-transport stress medicine of described goat, described feed additive by the anti-transport stress medicine of goat and normal feedstuff according to 8-10: 10000 weight ratio is mixed.
Further, described feed additive, described normal feedstuff is Semen Maydis particle, the anti-transport stress medicine of described goat and described Semen Maydis particle are mixed according to the weight ratio of 9: 10000.
Beneficial effect of the present invention is: Herba Polygoni cymosi, Perfoliate Knotweed Herb, inducing diuresis to remove edema, heat-clearing and toxic substances removing, cough-relieving.Radix Scutellariae, cures mainly epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis.Pericarpium Citri Reticulatae, the appetizing drying dampness to eliminate phlegm of regulating the flow of vital energy is controlled the spleen-stomach disease.Fructus Crataegi, has appetite promoting and the spleen strengthening, relieving asthma reduce phlegm, the effect of anti-bacteria, treatment abdominal pain diarrhea.Rhizoma Atractylodis, have drying damp and strengthening spleen, expelling wind and cold, the effect of improving eyesight.Fructus Hordei Germinatus (parched) has the effect that helps digestion, controls stomachache.Six songs, have the effect of invigorating the stomach and promoting digestion.Folium Nelumbinis, can be used for consumer edema.Cortex Moutan has nourishing YIN to lower pathogenic fire, separates the effect of speckle poison.Radix Paeoniae Rubra, has the effect of clots absorbing, pain relieving, removing heat from blood, detumescence.Fructus Gardeniae, has the effects such as hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, hemostasis, detumescence.Above-mentioned each component coupling, effective to the transport stress for the treatment of goat.Coordinate electrolysis multidimensional to use, can correct in time every Serum Indexes.
The specific embodiment
Illustrated embodiment is in order better content of the present invention to be described, but is not that content of the present invention only limits to illustrated embodiment.So those of ordinary skill in the art carry out nonessential improvement and adjustment according to foregoing invention content to embodiment, still belong to protection scope of the present invention.
The preparation of embodiment mono-Chinese medicine composition
Formula one
Chinese medicine composition, composed of the following components by weight: 10 parts of Herba Polygoni cymosis, 10 parts of Radix Scutellariaes, 10 parts of Pericarpium Citri Reticulataes, 8 parts of Fructus Crataegis, 10 parts of Rhizoma Atractylodis, 8 parts of Fructus Hordei Germinatus (parched)s, six 8 parts of songs, 6 parts of Flos Loniceraes, 6 parts, Folium Nelumbinis, 6 parts of Cortex Moutans, 5 parts of Radix Paeoniae Rubra, 5 parts of Fructus Gardeniaes.
Formula two
Chinese medicine composition, composed of the following components by weight: 12 parts of Herba Polygoni cymosis, 12 parts of Radix Scutellariaes, 12 parts of Pericarpium Citri Reticulataes, 10 parts of Fructus Crataegis, 8 parts of Rhizoma Atractylodis, 6 parts of Fructus Hordei Germinatus (parched)s, six 6 parts of songs, 4 parts of Flos Loniceraes, 4 parts, Folium Nelumbinis, 4 parts of Cortex Moutans, 3 parts of Radix Paeoniae Rubra, 3 parts of Fructus Gardeniaes.
Formula three
Described Chinese medicine composition, composed of the following components by weight: 15 parts of Herba Polygoni cymosis, 15 parts of Radix Scutellariaes, 15 parts of Pericarpium Citri Reticulataes, 14 parts of Fructus Crataegis, 14 parts of Rhizoma Atractylodis, 12 parts of Fructus Hordei Germinatus (parched)s, six 12 parts of songs, 10 parts of Flos Loniceraes, 10 parts, Folium Nelumbinis, 10 parts of Cortex Moutans, 9 parts of Radix Paeoniae Rubra, 9 parts of Fructus Gardeniaes.
The preparation of the embodiment anti-transport stress medicine of bis-goats and feed additive
One, electrolysis multidimensional
Electrolysis multidimensional comprises vitamin A (iu) 11023000, vitamin D3 (iu) 1653450, vitamin E (iu) 5512, vitamin K (milligram) 4409, vitamin B2 (milligram) 1102, vitamin B1 (milligram) 551, folic acid (milligram) 276, Acidum Pantothenicum (milligram) 8812, potassium %1.0, sodium %0.75 and vitamin B12 (milligram) 20.
Two, the anti-transport stress pharmaceutical formulation of goat
The anti-transport stress medicine of goat of described Chinese medicine composition, composed of the following components by weight:
Three, the anti-transport stress medicine of goat
The preparation of A Chinese medicine additive
Each component of described Chinese medicine composition composition formula three is fully pulverized by formula ratio, and mixed, obtain Chinese medicine additive;
The preparation of the anti-transport stress medicine of B goat
Electrolysis multidimensional, levamisole, sodium selenite and the iodine salt in the anti-transport stress pharmaceutical formulation of goat, mentioned are fully mixed with described Chinese medicine additive, obtain the anti-transport stress medicine of goat.
Four, feed additive
The anti-transport stress medicine of described goat stirring and evenly mixing by 8.3022kg, adds stirring and evenly mixing in 91.6978kg Semen Maydis particle, obtains feed additive.
The application of embodiment tri-feed additives
One, experiment grouping
1 experimental group
Be chosen at 30 goats that occur transport stress reaction in transportation, the feedstuff of freely ingesting and containing feed additive prepared by embodiment bis-.The mass percent of the feed additive adding in described feedstuff is 1%.
2 matched groups
Be chosen at 30 goats that occur transport stress reaction in transportation, edible normal diet.
Two, index detects
Blood sample acquisition method Baoding of standing, strength venous blood collection, blood sample is taked behind 7 days, administration after respectively at first 1 day of administration, administration for 15 days.Every each blood sampling 3-5ml, separation of serum is put-20 ℃ of refrigerators, does Biochemical Indices In Serum check, in 4d, completes.
Biochemical investigation method Physiological-biochemical Parameters send laboratory, the People's Hospital, Rongchang County to detect.
The serum glucose of experimental group and matched group goat, serum cortisol, blood urea nitrogen assay are in Table 1.From table 1, test group serum glucose, serum cortisol, blood urea nitrogen average are tending towards declining, and through t check, have utmost point significant difference (P < 0.01) with matched group.
The variation of table 1 serum glucose, serum cortisol, blood urea nitrogen etc.
Inorganic P, Cl in serum
-, Na
+, K
+the result of variations of content is in Table 2.Inorganic P, Cl in test group lowlenthal serum
-, Na
+, K
+average obviously raises, and through t check, there were significant differences (P < 0.05) with matched group.
Inorganic P, Cl in table 2 serum
-, Na
+, K
+the variation of content
The lymphocytic variation of T: test group is with matched group comparison, 7 days difference extremely significantly (P < 0.01) after the administration of T lymphocyte percentage, take medicine latter 7 days with take medicine latter 15 days significant differences (P < 0.05).The results are shown in Table 3.
The impact of table 3 on T lymphocyte percentage
%, sky
(*:P<0.01;**P<0.05)
The variation of total serum protein, albumin, globulin and albumins/globulins ratio: test group total serum protein average rises, and compares significant difference (P < 0.05) with matched group; The variation of serum globulin is consistent with total serum protein.Test group albumins/globulins ratio is on a declining curve, compares significant difference (P < 0.05) with matched group.The results are shown in Table 4.
The impact of table 4 total serum protein, albumin globulin and albumins/globulins ratio
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement technical scheme of the present invention, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of claim scope of the present invention.
Claims (8)
1. for the Chinese medicine composition of the anti-transport stress of goat, it is characterized in that, composed of the following components by weight: Herba Polygoni cymosi 10-12 part, Radix Scutellariae 10-12 part, Pericarpium Citri Reticulatae 10-12 part, Fructus Crataegi 8-10 part, Rhizoma Atractylodis 8-10 part, Fructus Hordei Germinatus (parched) 6-8 part, six bent 6-8 parts, Flos Lonicerae 4-6 part, Folium Nelumbinis 4-6 part, Cortex Moutan 4-6 part, Radix Paeoniae Rubra 3-5 part, Fructus Gardeniae 3-5 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, composed of the following components by weight: 10 parts of Herba Polygoni cymosis, 11 parts of Radix Scutellariaes, 12 parts of Pericarpium Citri Reticulataes, 9 parts of Fructus Crataegis, 9 parts of Rhizoma Atractylodis, 7 parts of Fructus Hordei Germinatus (parched)s, six 7 parts of songs, 5 parts of Flos Loniceraes, 5 parts, Folium Nelumbinis, 5 parts of Cortex Moutans, 4 parts of Radix Paeoniae Rubra, 4 parts of Fructus Gardeniaes.
3. the application of the Chinese medicine composition described in claim 1 or 2 in the anti-transport stress medicine of preparation goat.
4. the anti-transport stress medicine of goat that contains the Chinese medicine composition described in claim 1 or 2, is characterized in that, composed of the following components by weight:
5. the anti-transport stress medicine of the goat of Chinese medicine composition according to claim 4, is characterized in that, composed of the following components by weight:
6. the preparation method of the anti-transport stress medicine of goat claimed in claim 4, is characterized in that, comprises the following steps:
The preparation of A Chinese medicine additive
Each component in described Chinese medicine composition is fully pulverized by formula ratio, and mixed, obtain Chinese medicine additive;
The preparation of the anti-transport stress medicine of B goat
Electrolysis multidimensional, levamisole, sodium selenite and the iodine salt of formula ratio are fully mixed with described Chinese medicine additive, obtain the anti-transport stress medicine of goat.
7. the feed additive that contains the anti-transport stress medicine of goat claimed in claim 4, is characterized in that: described feed additive is mixed according to the weight ratio of 8-10:10000 by the anti-transport stress medicine of goat and normal feedstuff.
8. feed additive according to claim 7, is characterized in that: described normal feedstuff is Semen Maydis particle, and the anti-transport stress medicine of described goat and described Semen Maydis particle are mixed according to the weight ratio of 9:10000.
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CN105796811A (en) * | 2016-05-13 | 2016-07-27 | 云阳县林翔畜禽养殖专业合作社 | Traditional Chinese medicine formula for improving goat immunity and application method |
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CN1895291A (en) * | 2006-06-09 | 2007-01-17 | 陈永丽 | Nano-Chinese medicinal biological product and its preparation |
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