CN103110848B - Traditional Chinese medicine composition for treating sperm-abnormality infertility - Google Patents
Traditional Chinese medicine composition for treating sperm-abnormality infertility Download PDFInfo
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- CN103110848B CN103110848B CN201310077422.4A CN201310077422A CN103110848B CN 103110848 B CN103110848 B CN 103110848B CN 201310077422 A CN201310077422 A CN 201310077422A CN 103110848 B CN103110848 B CN 103110848B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating sperm-abnormality infertility. The traditional Chinese medicine composition is prepared from the following components: kadsura interior, rubus hirsutus, raspberry, dogwood, common dodder, teasel root, honeysuckle, corn silk, eclipta alba, gecko powder and liquorice. The traditional Chinese medicine composition can be clinically used for treating the sperm-abnormality infertility.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of dysspermatism infertility.
Background technology
Male infertility is the common difficult disease ，Ju World Health Organization (WHO) statistics of andrology, and the whole world approximately has 8% the couple at child-bearing age to suffer from sterility and infertility, and sickness rate fluctuates between 5%～35%.In can not family of procreation, wife's side factor accounts for 40%～50%, and bridegroom's or husband's side factor accounts for 20%～30%, and men and women's factor accounts for 30%～40%.More than 70% male sterility etiology unknown, even in the male sterility of the known cause of disease, its pathogenesis still can not be illustrated completely, so the diagnosis and treatment of male sterility, has its particularity and complexity.Dysspermatism refers to semen volume deficiency, sperm number few (or without sperm), sperm survival rate is low, energy is weak, sperm deformity, seminal fluid are not changed the series of symptoms such as anejaculation, is man's sterile main cause after marriage.The traditional Chinese medicine composition for treating dysspermatism infertility that the present invention prepares, has obtained good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment dysspermatism infertility that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Kadsura interior ， Fructus rubi tephrodis, Fructus Rubi, Fructus Corni, Semen Cuscutae, Radix Dipsaci, Flos Lonicerae, Stigma Maydis, Herba Ecliptae, Gecko powder, Radix Glycyrrhizae is made, according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Kadsura interior 40-60 part Fructus rubi tephrodis 30-50 part, Fructus Rubi 30-50 part, Fructus Corni 25-45 part, Semen Cuscutae 25-45 part, Radix Dipsaci 15-30 part, Flos Lonicerae 15-30 part, Stigma Maydis 15-30 part, Herba Ecliptae 10-20 part, Gecko powder 6-10 part, Radix Glycyrrhizae 6-10 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of 50 parts of ， Fructus rubi tephrodis of Kadsura interior, 40 parts of Fructus Rubies, 35 parts of Fructus Corni, 35 parts of Semen Cuscutae, 25 parts of Radix Dipsacis, 25 parts of Flos Loniceraes, 25 parts of Stigma Maydis, 15 parts of Herba Ecliptaes, 8 parts, Gecko powder, 8 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Kadsura interior: hemopoietic and blood, regulating menstruation seed.For deficient qi and blood, the paralysis of limb fiber crops, rheumatic arthralgia, deficient sterile, menoxenia, the diseases such as seminal emission nebulousurine.
Fructus rubi tephrodis: sweet, sour, warm.Return liver, kidney channel.The kidney invigorating and essence nourishing, reducing urination.For polyuria, sexual impotence, sterile, early whitening of beard and hair, the diseases such as carbuncle.
Fructus Rubi: sweet, sour, flat.Return liver, kidney channel.The liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, improving eyesight.For impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, the diseases such as early whitening of beard and hair.
Fructus Corni: acid, tepor, return liver, kidney channel.Liver and kidney tonifying, convergence are admittedly de-.Cure mainly and have a dizzy spell, the cards such as deafness and tinnitus.
Semen Cuscutae: pungent, sweet, put down, return liver,kidney,spleen warp.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, Gu tire stopping leak.For soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis etc.
Radix Dipsaci: bitter, pungent, tepor.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, only metrorrhagia.For aching pain in waist and back, damage muscle labor bone, metrorrhagia, seminal emission, is with inferior disease.
Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.For carbuncle furuncle, toxic-heat and blood stasis.
Stigma Maydis: sweet, light, flat.Return kidney, liver, gallbladder meridian.Inducing diuresis to remove edema, liver heat removing function of gallbladder promoting.Clinical in edema, dribbling urination, jaundice, cholecystitis, cholelithiasis, hypertension, diabetes, galactostasis etc.Diuretic medicine, diuretics with the action of eliminating dampness.
Herba Ecliptae: sweet, sour, cool.Return liver, kidney channel.Liver and kidney tonifying, cooling blood for hemostasis.Cure mainly deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair, spits blood, have blood in stool, and traumatic hemorrhage etc.
Gecko: salty, flat.Return lung, kidney channel.Kidney tonifying tonifying the lung, Dingchuan antitussive.For deficiency of both the lung and kidney asthma and cough, cough due to consumptive disease, spitting of blood, impotence due to deficiency of the kidney, seminal emission, frequent micturition, quenches one's thirst etc.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Kadsura interior of the present invention has the effect of regulating menstruation seed, for monarch drug ， Fructus rubi tephrodis has the kidney invigorating, benefit essence, supporing yang effect, Fructus Rubi has liver and kidney tonifying, the effect of controlling nocturnal emission with astringent drugs reducing urination, two medicines are ministerial drug, Fructus Corni liver and kidney tonifying, Semen Cuscutae the kidney invigorating and essence nourishing, Radix Dipsaci bone and muscle strengthening, Flos Lonicerae heat-clearing and toxic substances removing, Stigma Maydis inducing diuresis to remove edema, Herba Ecliptae liver and kidney tonifying, Gecko powder kidney tonifying tonifying the lung, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, compatibility is used, and reaches the object for the treatment of dysspermatism infertility.
Chinese medicine composition of the present invention is used in 2007 to 2010 clinical observation dysspermatism infertility disease 55 routine patients, and clinical report is as follows:
1, physical data
In 55 routine patients, age 22-41 year, average 27.9 years old, course of disease 1-10a, average 5.2a.Be after marriage more than matrimonial cohabitation 1a, sexual life is normal, does not take any contraceptives and does not educate, and all get rid of wife's side Infertile factors, and seminal fluid conventional analysis has the male sterility patient of 1 or 1 above Indexes Abnormality.
2, diagnostic criteria
With reference to < < traditional Chinese medical science disease diagnoses and treatment standard > > and < < new Chinese medicine guideline of clinical investigations > >, formulate:
Primary symptom: sterile, libido is indifferent, sperm is rare, and sperm motility is low, and motility of sperm is low, and dead, teratospermia increases.Inferior disease: soreness of the waist and knees, nocturia increases, and pale tongue with thin fur is white, a little less than deep-thready pulse.Above primary symptom " sterile " must possess, have concurrently all the other every in 1 and time disease 2, diagnosable.Lab testing: main manifestations is that semen quality is abnormal.
3, Therapeutic Method
3.1 prescriptions: Kadsura interior 50g ， Fructus rubi tephrodis 40g, Fructus Rubi 40g, Fructus Corni 35g, Semen Cuscutae 35g, Radix Dipsaci 25g, Flos Lonicerae 25g, Stigma Maydis 25g, Herba Ecliptae 15g, Gecko powder 8g, Radix Glycyrrhizae 8g.
3.2 preparation methoies: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose every day 2 times, 90 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 check the > with diagnosis handbook > with reference to WHO < < infertile couples standard:
Cure: spouse becomes pregnant or seminal fluid detects indices recovery normally;
Effective: though do not become pregnant, sperm concentration > 20 * 10 after treating 3 months
9/ L, motility of sperm a level+b level > 50% or a level > 25%, motility rate > 60%;
Effective: to treat sperm concentration, sperm motility rate, motility of sperm after 3 months and have at least 1 to improve > 30%;
Invalid: after treatment, clinical symptoms, sign and seminal fluid routine examination indices are without obvious change.
4.2 results: in 55 routine patients, cure 32 examples (58.2%), effective 13 examples (23.7%), effective 8 examples (14.5%), invalid 2 examples (3.6%), total effective rate is 96.4%.
5, model case
5.1 Liu, 34 years old, within 2 years after marriage, do not educate, its wife is healthy.Conscious libido is indifferent, and the soreness of waist is easily tired.Semen efamination: the about 1.5ml of semen volume, liquefaction in 30 minutes, pH value 7.8, sperm concentration 1.8 * 10
9/ L, activity ratio 0.30, abnormal rate 0.50, energy a level 0.03, b level 0.12; Leukocyte 2-5/HP.Be diagnosed as infertility.Take the Chinese medicine composition that the present invention treats dysspermatism infertility and treat, treat after 1 course for the treatment of the about 3ml of semen volume, sperm concentration 83 * 10
9/ L, activity ratio 0.65, abnormal rate 0.30, energy a level 0.28, b level 0.34, all diseases all disappear, continue to take 1 month, and its wife is conceived.
5.2 grandsons, 28 years old, marry and do not educate for 5 years.The wife's side is healthy, through gynecologial examination without abnormality.Readme soreness of the waist and knees, weak, to be off one's feed, libido is indifferent, checks that meeting color white light is white, extremities being not warm, light red tongue, tongue is white, deep,thready and forceless pulse.Andrology's inspection, external genitalia official grows normally, and testis, epididymis are without enlargement tenderness, and bilateral spermatic vein is without varicose.Semen analysis checks: sperm sum 1.6 * 10
9/ L, semen volume 3.5ml, sperm motility 30%, motility of sperm a level and b level 15%, c level is 50%, 1.2 hours semen liquefaction time.Taken the Chinese medicine composition that the present invention treats dysspermatism infertility, 1 course for the treatment of, symptom disappears substantially.Semen analysis checks: semen volume 4.5ml, sperm sum 86 * 10
9/ L, sperm motility 0.73, energy a level, b level 40%, semen liquefaction time 30min, disease obtains recovery from illness, continues to take 2 months, and its wife is conceived.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine composition for the treatment of dysspermatism infertility, and it is to be made by following raw material medicaments: Kadsura interior 40g ， Fructus rubi tephrodis 30g, Fructus Rubi 30g, Fructus Corni 25g, Semen Cuscutae 25g, Radix Dipsaci 15g, Flos Lonicerae 15g, Stigma Maydis 15g, Herba Ecliptae 10g, Gecko powder 6g, Radix Glycyrrhizae 6g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of dysspermatism infertility, and it is to be made by following raw material medicaments: Kadsura interior 50g ， Fructus rubi tephrodis 40g, Fructus Rubi 40g, Fructus Corni 35g, Semen Cuscutae 35g, Radix Dipsaci 25g, Flos Lonicerae 25g, Stigma Maydis 25g, Herba Ecliptae 15g, Gecko powder 8g, Radix Glycyrrhizae 8g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of dysspermatism infertility, and it is to be made by following raw material medicaments: Kadsura interior 60g ， Fructus rubi tephrodis 50g, Fructus Rubi 50g, Fructus Corni 45g, Semen Cuscutae 45g, Radix Dipsaci 30g, Flos Lonicerae 30g, Stigma Maydis 30g, Herba Ecliptae 20g, Gecko powder 10g, Radix Glycyrrhizae 10g.
Claims (2)
1. treat a Chinese medicine composition for dysspermatism infertility, it is characterized in that being made by following raw material medicaments:
Kadsura interior 40-60 part ， Fructus rubi tephrodis 30-50 part, Fructus Rubi 30-50 part, Fructus Corni 25-45 part, Semen Cuscutae 25-45 part, Radix Dipsaci 15-30 part, Flos Lonicerae 15-30 part, Stigma Maydis 15-30 part, Herba Ecliptae 10-20 part, Gecko powder 6-10 part, Radix Glycyrrhizae 6-10 part.
2. Chinese medicine composition according to claim 1, its feature is being made by following raw material medicaments:
40 parts of 50 parts of ， Fructus rubi tephrodis of Kadsura interior, 40 parts of Fructus Rubies, 35 parts of Fructus Corni, 35 parts of Semen Cuscutae, 25 parts of Radix Dipsacis, 25 parts of Flos Loniceraes, 25 parts of Stigma Maydis, 15 parts of Herba Ecliptaes, 8 parts, Gecko powder, 8 parts, Radix Glycyrrhizae.
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| CN103877213B (en) * | 2014-04-13 | 2015-07-29 | 施维华 | A kind of Chinese medicine preparation for the treatment of male sterility |
| CN105495386A (en) * | 2015-02-13 | 2016-04-20 | 王学兵 | Blood nourishing and essence enriching medicated food and preparation method thereof |
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