CN106267086A - A kind of Chinese medicine preparation treating primary glaucoma - Google Patents

A kind of Chinese medicine preparation treating primary glaucoma Download PDF

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CN106267086A
CN106267086A CN201610802677.6A CN201610802677A CN106267086A CN 106267086 A CN106267086 A CN 106267086A CN 201610802677 A CN201610802677 A CN 201610802677A CN 106267086 A CN106267086 A CN 106267086A
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herba
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刘珣
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Abstract

The invention discloses a kind of Chinese medicine preparation treating primary glaucoma, be made up of Nux Prinsepiae, Cortex Acanthopancis, Herba Cayatiae Japonicae, Herba Lactucae Indicae, Radix Actinidiae Polygamae, Fructus Atriplicis Sibiricae, Herba Violae, Herba Ixeritis chinensis, Herba Taxilli, the Radix Aucklandiae, Fructus Mori, Gueldenstaedtia verna, Rhizoma Zingiberis and Radix Glycyrrhizae Preparata.The present invention is by multi-medicament scientific compatibility, to adapt to the treatment requirement of the complicated state of an illness, there is wind dispelling heat radiation, nourishing the liver to improve visual acuity, liver and kidney tonifying, dissipating blood stasis for subsidence of swelling, the effect of warming spleen and stomach for dispelling cold, it is possible to effectively reduce and maintain intraocular pressure, control optic atrophy, recover optic nerve and visual function, improve antioxidant ability of organism, improve ocular circulation, to reach to improve the purpose of patient's vision, evident in efficacy, treating both the principal and secondary aspects of a disease, have no side effect, non-relapse after healing.

Description

A kind of Chinese medicine preparation treating primary glaucoma
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation treating primary glaucoma.
Background technology
Glaucoma is to cause excavation of optic disc, defect of visual field owing to intraocular pressure increases, and may finally cause blind serious ocular Sick.Normal intraocular tension, at 10-21mmHg, is pathological phenomenon more than 24mmHg.Intraocular pressure increases can cause visual function damage, and optic disc goes out The biggest and deep depression, Glaucomatous typical case seen from the visual field changes.It is more long that intraocular pressure increases the persistent period, and visual function damage is the tightest Weight.
Glaucoma is divided into constitutional, Secondary cases and congenital three classes clinically.Common with constitutional.According to statistics, China is sent out Sick rate is 0.89-2.6%, and blind rate reaches 19.62%.The morbidity of primary glaucoma, anatomical factors is fundamental cause, but emotion Unstable, overwork, be risk factor with transition between at the moment etc..Doctor trained in Western medicine operation and the myosis Drug therapy of using more, but up to now Can not make recovered once again by the optic nerve of organic lesion and visual function.At present, the Chinese medicine for the treatment of primary glaucoma is few, And there is the deficiencies such as curative effect is inconspicuous, toxic and side effects is big, easy recurrence.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, it is provided that a kind of compatibility is reasonable, evident in efficacy, have no side effect, be difficult to The Chinese medicine preparation of the treatment primary glaucoma of recurrence.
It is an object of the invention to be achieved through the following technical solutions:
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 3-8 part, Cortex Acanthopancis 10-20 part, Herba Cayatiae Japonicae 15-25 part, Herba Lactucae Indicae 10-15 part, Radix Actinidiae Polygamae 10-20 part, Fructus Atriplicis Sibiricae 6-10 part, pale reddish brown Fourth 10-20 part, Herba Ixeritis chinensis 8-12 part, Herba Taxilli 5-10 part, Radix Aucklandiae 3-7 part, Fructus Mori 10-15 part, Gueldenstaedtia verna 8-12 part, Rhizoma Zingiberis 3-7 part, Radix Glycyrrhizae Preparata 10-20 part.
Preferably, a kind of Chinese medicine preparation treating primary glaucoma, it is made up of the raw material of following weight portion: Nux Prinsepiae 5 parts, Cortex Acanthopancis 15 parts, Herba Cayatiae Japonicae 20 parts, Herba Lactucae Indicae 13 parts, Radix Actinidiae Polygamae 15 parts, Fructus Atriplicis Sibiricae 8 parts, Herba Violae 15 parts, mountain bitter Mai 10 parts, Herba Taxilli 8 parts, the Radix Aucklandiae 5 parts, Fructus Mori 13 parts, Gueldenstaedtia verna 10 parts, Rhizoma Zingiberis 5 parts, Radix Glycyrrhizae Preparata 15 parts.
The preparation method of the Chinese medicine preparation that the present invention treats primary glaucoma is as follows:
(1) weigh the crude drug of formula ratio and join in marmite, adding cold water to not having medical material and soaking 1 hour, so Continue little fire after burning extremely boiling in rear to decoct slowly 30 minutes, filter to obtain 1 filtrate；
(2) in marmite, add about 800ml cold water again, continue to burn to boiling, after slow fire decocts 30 minutes, filter 2 filtrates；
(3) 1 filtrate and 2 filtrates being merged, heating is concentrated into 400ml.
The present invention treats usage and the consumption of the Chinese medicine preparation of primary glaucoma: decocting is administered orally, and a side is potion, one Potion, twice on the one, respectively takes 200ml in 1 hour after meal sooner or later.Within 10 days, being 1 course for the treatment of, general 2-5 can cure the course for the treatment of.
The pharmacology of each raw material is as follows:
Nux Prinsepiae: sweet in the mouth, cold in nature.Return liver, the heart, spleen, lung meridian.Wind and heat eliminating, nourishing the liver to improve visual acuity, calm the nerves.Main conjunctival congestion and swelling pain, dim Photophobia, the rotten many tears of the corner of the eyes, uneasy sleeping at night
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.Return liver, kidney channel.Wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, inducing diuresis to remove edema.For Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, tinea pedis.
Herba Cayatiae Japonicae: bitter in the mouth, acid, cold in nature.GUIXIN, liver, stomach warp.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Carbuncle, furuncle, mumps, red Poison, rheumatalgia, jaundice, dysentery, hematuria, nebulousurine.
Herba Lactucae Indicae: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, stomach invigorating.For appendicitis, tonsillitis, furuncle toxic swelling, Dyspepsia does not disappears, postnatal blood stasis.
Radix Actinidiae Polygamae: acrid in the mouth, property is put down.Return bladder, stomach, large intestine channel.Dispelling wind to relieve the exterior syndrome pain relieving.Control and violate outside ailment said due to cold or exposure, attack tooth body, Dental pain, local swelling, or take out and take along sample sense.Or ailment said due to cold or exposure bundle table, stiffness along the spinal column pain, there is contracture sense, occur together heat, aversion to cold, thin fur arteries and veins Floating.
Fructus Atriplicis Sibiricae: bitter in the mouth, pungent, property is put down.Return Liver Channel.Suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Having a headache for dizziness due to hyperactivity of liver-YANG, stagnation of liver-QI is coerced Bitterly, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the disease such as skin pruritus.
Herba Violae: bitter in the mouth, pungent, cold in nature.GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Cure mainly jaundice, dysentery, mammary gland Traumatic injury, carbuncle, venom etc. are controlled in inflammation, conjunctival congestion and swelling pain, pharyngitis external application.
Herba Ixeritis chinensis: acrid in the mouth, hardship, cold nature.Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, removing heat from blood, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing. For acute appendicitis, lung abscess high heat, cough vomiting bloody pus, pyretic toxicity skin ulcer furuncle, furuncle pain is swollen, chest and abdomen pain, appendicitis, enteritis, dysentery, puerperal abdomen Bitterly, dysmenorrhea.
Herba Taxilli: bitter in the mouth, sweet, property is put down.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive.Main soreness of waist and knee joint, muscle The atrophic debility of bones is weak, and limbs are hemiplegia, rheumatic arthralgia, and head mistake is dizzy, frequent fetal movement, metrostaxis.For rheumatic arthralgia, soreness of the waist and knees, muscle Bone is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement, hypertension.
The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature.Promoting the circulation of QI to relieve pain, intestinal stasis relieving in tune.Cure mainly born of the same parents and coerce distension foot, abdominal distention, tell and have loose bowels, Weight after dysentery.
Fructus Mori: sweet in the mouth, property is put down.Return liver, kidney, heart channel.Nourishing YIN and benefiting blood, promotes the production of body fluid, intestine moistening.Main deficiency of the liver and kindey and blood deficiency damage of essence Have a dizzy spell, soreness of waist tinnitus, early whitening of beard and hair, insomnia and dreamful sleep, Tianjin wound is thirsty, quenches one's thirst, dryness of the intestine constipation
Gueldenstaedtia verna: sweet in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.For carbuncle furuncle, scrofula, erysipelas, conjunctival congestion swells Bitterly, jaundice, enteritis, dysentery, venom.
Rhizoma Zingiberis: acrid in the mouth, property heat.Return spleen, stomach, lung meridian.Warming spleen and stomach for dispelling cold i.e. blood circulation promoting, after clothes, gastrointestinal has warming sense； Arresting vomiting by invigorating the stomach；By sympathetic activation, blood pressure is made to increase.Function is cold relieving warming middle-JIAO, recuperating depleted YANG.It is mainly used in stomachache of vomiting and diarrhoea, limb Cold faint pulse, cold fluid-retention coughs, stomachache with cool feeling, the disease such as arthralgia due to cold-dampnes.
Radix Glycyrrhizae Preparata: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, the mediation property of medicine.
In the present invention, Nux Prinsepiae is monarch, wind and heat eliminating, nourishing the liver to improve visual acuity, effectively reduces and maintains intraocular pressure；Cortex Acanthopancis, Herba Cayatiae Japonicae, Herba Lactucae Indicae and Radix Actinidiae Polygamae are minister, and expelling wind and removing dampness, liver and kidney tonifying, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling improve ocular circulation, carry High antioxidant ability of organism；Fructus Atriplicis Sibiricae, Herba Violae, Herba Ixeritis chinensis and Herba Taxilli are assistant, and suppressing the hyperactive liver improving eyesight, removing heat from blood detumescence, blood stasis dispelling are only Bitterly, notable intraocular pressure of alleviating raises the distending pain of the head and eyes caused；The Radix Aucklandiae, Fructus Mori, Gueldenstaedtia verna, Rhizoma Zingiberis and Radix Glycyrrhizae Preparata are for making, and dissipating blood stasis disappears Swollen, disinfecting pain relieving, warming spleen and stomach for dispelling cold, coordinating the actions of various ingredients in a prescription, draw all medicine liters and reach eyes, recover optic nerve and visual function.Above compatibility of drugs Use, reach to treat the purpose of primary glaucoma.
The present invention treats the Chinese medicine preparation of primary glaucoma, by multi-medicament scientific compatibility, to adapt to the complicated state of an illness Treatment requirement, has wind dispelling heat radiation, nourishing the liver to improve visual acuity, liver and kidney tonifying, dissipating blood stasis for subsidence of swelling, the effect of warming spleen and stomach for dispelling cold, it is possible to effectively reduce With maintenance intraocular pressure, control optic atrophy, recover optic nerve and visual function, improve antioxidant ability of organism, improve ocular blood Circulation, to reach to improve the purpose of patient's vision, evident in efficacy, treating both the principal and secondary aspects of a disease, has no side effect, non-relapse after healing.
Detailed description of the invention
The present invention is explained further below in conjunction with embodiment, but the present invention is not done any type of limit by embodiment Fixed.
Embodiment 1
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 8 parts, five Cortex Acanthopanacis Radicis 20 parts, Herba Cayatiae Japonicae 25 parts, Herba Lactucae Indicae 10 parts, Radix Actinidiae Polygamae 10 parts, Fructus Atriplicis Sibiricae 6 parts, Herba Violae 20 parts, Herba Ixeritis chinensis 8 parts, Herba Taxilli 5 parts, the Radix Aucklandiae 3 parts, Fructus Mori 15 parts, Gueldenstaedtia verna 12 parts, Rhizoma Zingiberis 3 parts, Radix Glycyrrhizae Preparata 10 parts.
The preparation method of the Chinese medicine preparation that the present invention treats primary glaucoma is as follows:
(1) weigh the crude drug of formula ratio and join in marmite, adding cold water to not having medical material and soaking 1 hour, so Continue little fire after burning extremely boiling in rear to decoct slowly 30 minutes, filter to obtain 1 filtrate；
(2) in marmite, add about 800ml cold water again, continue to burn to boiling, after slow fire decocts 30 minutes, filter 2 filtrates；
(3) 1 filtrate and 2 filtrates being merged, heating is concentrated into 400ml.
The present invention treats usage and the consumption of the Chinese medicine preparation of primary glaucoma: decocting is administered orally, and a side is potion, one Potion, twice on the one, respectively takes 200ml in 1 hour after meal sooner or later.It within 10 days, it was 1 course for the treatment of.
Embodiment 2
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 7 parts, five Cortex Acanthopanacis Radicis 18 parts, Herba Cayatiae Japonicae 23 parts, Herba Lactucae Indicae 12 parts, Radix Actinidiae Polygamae 13 parts, Fructus Atriplicis Sibiricae 7 parts, Herba Violae 18 parts, Herba Ixeritis chinensis 9 parts, Herba Taxilli 6 parts, the Radix Aucklandiae 4 parts, Fructus Mori 14 parts, Gueldenstaedtia verna 11 parts, Rhizoma Zingiberis 4 parts, Radix Glycyrrhizae Preparata 12 parts.
Remaining is with embodiment 1.
Embodiment 3
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 5 parts, five Cortex Acanthopanacis Radicis 15 parts, Herba Cayatiae Japonicae 20 parts, Herba Lactucae Indicae 13 parts, Radix Actinidiae Polygamae 15 parts, Fructus Atriplicis Sibiricae 8 parts, Herba Violae 15 parts, Herba Ixeritis chinensis 10 Part, Herba Taxilli 8 parts, the Radix Aucklandiae 5 parts, Fructus Mori 13 parts, Gueldenstaedtia verna 10 parts, Rhizoma Zingiberis 5 parts, Radix Glycyrrhizae Preparata 15 parts.
Remaining is with embodiment 1.
Embodiment 4
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 4 parts, five Cortex Acanthopanacis Radicis 13 parts, Herba Cayatiae Japonicae 18 parts, Herba Lactucae Indicae 14 parts, Radix Actinidiae Polygamae 18 parts, Fructus Atriplicis Sibiricae 9 parts, Herba Violae 13 parts, Herba Ixeritis chinensis 11 Part, Herba Taxilli 9 parts, the Radix Aucklandiae 6 parts, Fructus Mori 12 parts, Gueldenstaedtia verna 9 parts, Rhizoma Zingiberis 6 parts, Radix Glycyrrhizae Preparata 17 parts.
Remaining is with embodiment 1.
Embodiment 5
A kind of Chinese medicine preparation treating primary glaucoma, is made up of the raw material of following weight portion: Nux Prinsepiae 3 parts, five Cortex Acanthopanacis Radicis 10 parts, Herba Cayatiae Japonicae 15 parts, Herba Lactucae Indicae 15 parts, Radix Actinidiae Polygamae 20 parts, Fructus Atriplicis Sibiricae 10 parts, Herba Violae 10 parts, Herba Ixeritis chinensis 12 Part, Herba Taxilli 10 parts, the Radix Aucklandiae 7 parts, Fructus Mori 10 parts, Gueldenstaedtia verna 8 parts, Rhizoma Zingiberis 7 parts, Radix Glycyrrhizae Preparata 20 parts.
Remaining is with embodiment 1.
Clinical data:
Physical data: clinical observation clinical diagnosis is Endothelium in Patients with Primary Glaucoma 60 example, is randomly divided into two groups；Treatment group 30 Example, the maleest 14 examples, female 16 example, age 30-65 year, 47.2 ± 17.3 years old mean age；Matched group 30 example, the maleest 15 examples, Female 15 example, age 28-68 year, 48.1 ± 18.5 years old mean age.2 groups of physical data comparing difference not statistically significant (P ＞ 0.05), there is comparability.
Diagnostic criteria: intraocular pressure between 25-55mmHg, cardinal symptom: optic atrophy, platycoria, eyeball congestion, eye Swollen and with headache, reading difficulty.
Discharge standard: the secondary glaucoma caused by a variety of causes；It is associated with severe corneal, iris pathological changes person；Glaucoma Postoperative generation severe complication, such as ciliary block glaucoma, anterior chamber's massive hemorrhage, postoperative anterior cham ber intraocularlenses etc.；Age is big less than 18 years old In the patient of 75 years old；Gestation and women breast-feeding their children；It is associated with the severe primary diseases such as liver, kidney, hemopoietic system, hormonal system And psychotic；The patient taken medicine on time the most on request；The patient followed up a case by regular visits to can not be carried out on request.
Therapeutic Method: treatment group takes the Chinese medicine preparation of the present invention, potion on the one, and twice on the one, 1 hour after meal sooner or later each Take 200ml.Within 10 days, it was 1 course for the treatment of, shares 4 courses for the treatment of of medicine.Matched group takes ATP20mg, VB11 sheet, methycobal 500 μ G, three times a day.Within 10 days, it was 1 course for the treatment of, shares 4 courses for the treatment of of medicine.
Treatment criterion: reference " Chinese medicine Clinical Researches of New Drugs guideline " (National Drug Administration. the traditional Chinese medical science Medicine Clinical Researches of New Drugs guideline [M]. Beijing: China Medical Science Press, 2002:5) formulate:
Cure: vision reaches 1.0 or improves more than 5 row, and intraocular pressure controls at below 21mmHg, each clinical symptom disappearance；
Effective: vision improves more than 3 row, intraocular pressure controls at below 21mmHg, each clinical symptom disappearance；
Effective: vision improves more than 1-3 row, intraocular pressure reduces more than 5mmHg, and each clinical symptoms has alleviated；
Invalid: vision and intraocular pressure have no that significant change, each clinical symptoms the most all do not improve.
Cure rate=(curing/total number of cases) × 100%.
Total effective rate=[(cure+effective+effectively)/total number of cases] × 100%.
Statistical method: using SPSS17.0 statistical software to carry out statistical analysis, measurement data is with mean ± standard deviation (x ° ± s) represents, uses t inspection, and the comparison of enumeration data rate uses χ2Inspection.
Therapeutic outcome: the therapeutic outcome for the treatment of group and matched group is shown in Table 1.
The therapeutic outcome after Chinese medicine preparation of the present invention applied by table 1
Compare with matched group, P ＜ 0.05.
As shown in Table 1, treatment group cures 16 examples, effective 8 examples, effective 5 examples, invalid 1 example, and cure rate is 53.3%, always has Efficiency is 96.7%；Matched group cures 6 examples, effective 5 examples, effective 6 examples, invalid 13 examples, and cure rate is 20.0%, and total effective rate is 56.7%.2 groups of cure rates and total effective rate comparing difference statistically significant (P ＜ 0.05), treatment group curative effect is better than matched group.
In treatment clinical course, the vital sign (blood pressure, heart rate, body temperature, breathing) of patient, physical examination, blood biochemical Analysis, electrocardiogram and routine urinalysis Non Apparent Abnormality during treating.

Claims (2)

1. the Chinese medicine preparation treating primary glaucoma, it is characterised in that be made up of the raw material of following weight portion: Rui Core 3-8 part, Cortex Acanthopancis 10-20 part, Herba Cayatiae Japonicae 15-25 part, Herba Lactucae Indicae 10-15 part, Radix Actinidiae Polygamae 10-20 part, Fructus Atriplicis Sibiricae 6-10 Part, Herba Violae 10-20 part, Herba Ixeritis chinensis 8-12 part, Herba Taxilli 5-10 part, Radix Aucklandiae 3-7 part, Fructus Mori 10-15 part, Gueldenstaedtia verna 8- 12 parts, Rhizoma Zingiberis 3-7 part, Radix Glycyrrhizae Preparata 10-20 part.
Chinese medicine preparation the most according to claim 1, it is characterised in that be made up of the raw material of following weight portion: Nux Prinsepiae 5 Part, Cortex Acanthopancis 15 parts, Herba Cayatiae Japonicae 20 parts, Herba Lactucae Indicae 13 parts, Radix Actinidiae Polygamae 15 parts, Fructus Atriplicis Sibiricae 8 parts, Herba Violae 15 parts, mountain hardship Mai 10 parts, Herba Taxilli 8 parts, the Radix Aucklandiae 5 parts, Fructus Mori 13 parts, Gueldenstaedtia verna 10 parts, Rhizoma Zingiberis 5 parts, Radix Glycyrrhizae Preparata 15 parts.
CN201610802677.6A 2016-08-28 2016-08-28 A kind of Chinese medicine preparation treating primary glaucoma Pending CN106267086A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106728358A (en) * 2017-02-16 2017-05-31 牡丹江医学院 A kind of Chinese medicine composition of promotion wound healing after operation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105055936A (en) * 2015-07-27 2015-11-18 朱爱菊 Traditional Chinese medicine for treating primary angle closed glaucoma and preparation method of traditional Chinese medicine
CN105560375A (en) * 2014-10-30 2016-05-11 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine for treating primary glaucoma
CN105616695A (en) * 2014-10-30 2016-06-01 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine composition for treating primary glaucoma

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105560375A (en) * 2014-10-30 2016-05-11 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine for treating primary glaucoma
CN105616695A (en) * 2014-10-30 2016-06-01 青岛信立德中药技术研究开发有限公司 Traditional Chinese medicine composition for treating primary glaucoma
CN105055936A (en) * 2015-07-27 2015-11-18 朱爱菊 Traditional Chinese medicine for treating primary angle closed glaucoma and preparation method of traditional Chinese medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张俊庭主编: "《中医奇方妙治真传》", 30 June 1994, 中医古籍出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106728358A (en) * 2017-02-16 2017-05-31 牡丹江医学院 A kind of Chinese medicine composition of promotion wound healing after operation

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