CN103109980A - Chinese herbal medicine feed additive capable of improving immunity, preparation method thereof and feed - Google Patents

Chinese herbal medicine feed additive capable of improving immunity, preparation method thereof and feed Download PDF

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CN103109980A
CN103109980A CN2013100686473A CN201310068647A CN103109980A CN 103109980 A CN103109980 A CN 103109980A CN 2013100686473 A CN2013100686473 A CN 2013100686473A CN 201310068647 A CN201310068647 A CN 201310068647A CN 103109980 A CN103109980 A CN 103109980A
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CN103109980B (en
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裴兰英
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Liaocheng University
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Abstract

The invention provides a Chinese herbal medicine feed additive capable of improving the immunity. The Chinese herbal medicine feed additive is characterized by comprising the following raw materials: willow herb, red-backed vegetable, Chinese yam, herba epimedii, jiaoshen yeast, caulis spatholobi, puerarin, cimicifugae foetidae, Chinese herbaceous peony, jian yeast, rheum officinale, mangnolia officinalis, cyrtomium fortunei, liquorice, radix scutellariae, honeysuckle stem, gynostemma pentaphylla, fuling, soy isoflavone, soyasaponin and additional components, wherein the additional components comprise vitamin A, vitamin B, vitamin C, chromium trichloride, huanyuan gel, xylitol and mannitol crystals according to the proportion of 0.2:0.2:0.5:0.3:1:1:1. The Chinese herbal medicine feed additive can replace antibiotics and medicines and has no toxic and side effects; the immunity of animals such as pigs, chicken and ducks can be obviously improved; relatively high economical benefits can be achieved with relatively small investment; antibiotic and chemical medicine residues are avoided; and an effective way is supplied to reducing the antibiotic residues in animal products.

Description

A kind of Chinese herbal feed additive, preparation method and feed that improves immunity
Technical field
The invention belongs to the field of fodder of livestock, relate in particular to a kind of Chinese herbal feed additive, preparation method and feed that improves immunity.
Background technology
Diarrhoea is a kind of typical multi-factor disease in Swine Production, and according to statistics, the incidence of disease of grice diarrhoea is 35%, and its indirect loss shows that again the healing Piglet Development is slow, and feed conversion rate is low, the development of serious threat pig industry.Since in May, 2006, priority eruption and prevalence porcine hyperthermia, cause large quantities of pig Mortalities throughout the country, causes great economic loss.So far, hyperpyrexia disease is Epidemics in the swinery in 22 provinces, the whole nation still, and the healthy growth of harm pig is threatening the development of pig industry.The adverse consequences that the use of antibiotic in cultivation brings is all fully realized.Many experts think in the whole nation hypoimmunity that major reason is pig in a lot of areas pandemic " porcine hyperthermias ", and premunition is low.
In mid-term in last century, the zoologist finds that the antibiotic of interpolation low dosage in feed can significantly promote the growth of livestock and poultry, and it uses in feed widely immediately.The antibiotic of kind more than 20 and the use of synthesising bacteria anti-reflecting medicine in feed of tens kinds are arranged according to statistics in the world.Fodder antibiotics promotes growth of animal in the prevention Animal diseases, improves the price of deed and has all played positive effect.But, use for a long time antibiotic can produce drug resistance, make antibiotic become invalid on the one hand, cause on the other hand antibiotic abuse, the serious harm human health; Along with the development of time, the drug-fast increase of bacterium, the problems such as medicament residue of livestock products have consisted of serious threat to health, and the negative effect that feeding antibiotic causes becomes the focus of people's perfusion.Green, pollution-free, effective antibiotic substitute products are the trend of following animal husbandry development, and this is to promoting the development of China's animal husbandry, ensure that people are healthy to have a profound significance.Add, use a large amount of antibiotic or chemicals in feed and feeding process, although bacteria resistance diarrhoea is effective like this, but invalid to virus diarrhea, and medicament residue is serious, does not meet food security and the healthy aquaculture development trend of people's growing interest.
Current, in China's feedstuff industry, along with " feed and feed addictive management rules " promulgate and execution requirements, forbid the drug abuse additive, the feed addictive selectable range is more and more less, and the probiotics of lived short long agent and health-care agent is maximum bright spot.
The application of China's Chinese medicine has more and more obtained the approval of international community, its multiple medicinal material is evident in efficacy, by lot of experiments and research, finds to add the feed that is compounded with a certain amount of Chinese medicine, replace antibiotic, improving animal immunizing power has remarkable result, can effectively to anti-inflammatory and infection, guarantee the health of animal intestinal, control animal diarrhea, improve breeding performonce fo animals, after especially adding the batching of certain proportional quantity, successful is strengthened.Chinese herbal medicine acts on advantages such as extensively, can not producing drug resistance and gains great popularity with its aboundresources.The invention provides and improve a kind of Chinese herbal feed additive that improves immunity, replace antibiotic and anti-parasite medicine, avoided medicament residue and antibiotics resistance drawback.Through the literature search to prior art, still the report relevant with raising animal immunizing power of the present invention and anti-infectious Chinese herbal feed additive found at the end.
Summary of the invention
a kind of Chinese herbal feed additive that improves immunity, it is characterized in that, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
a kind of Chinese herbal feed additive that improves immunity, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 3~5 parts, Fructus Hordei Germinatus, 1~3 part of calcium monohydrogen phosphate, be 1~3 part of gustin, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 0.5~8 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme, 1~5 part, nucleotides, 1~3 part of staphylococcus lysozyme, 1~3 part of methionine, 1~2 part, folic acid, β-1~2 part of calabash radish element, 1~3 part of acidulant.
The feed that a kind of Chinese herbal feed additive that improves immunity is made, described acidulant is that acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
A kind of method that Chinese herbal feed additive that improves immunity is made is characterized in that step is as follows:
1) select commercially available micronizer;
2) take 10~30 parts of the Lythrum salicarves of respective amount according to a handling capacity of micronizer, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
Step 1, take above-mentioned each composition by said ratio, be Lythrum salicaria, red back of the body dish, Chinese yam, barrenwort, stir-baked MASSA FERMENTATA MEDICI-NALIS, reticulate millettia, the root of kudzu vine, rattletop, Chinese herbaceous peony, build song, rheum officinale, the bark of official magnolia, rhizome of cyrtomium, Radix Glycyrrhizae, the root of large-flowered skullcap, caulis lonicerae, gynostemma pentaphylla, Poria cocos, by micronizer, make superfine powder to 200 order after pulverizing stand-by; Described Lythrum salicaria, red back of the body dish are root, cauline leaf, the flower below 9wt% with dried water content, are placed in the frying pot in 130~150 ℃ of fryings 10 minutes, until till the jaundice of surface, namely take out standby;
Step 2, take isoflavones, soyasaponins and the described supplementary element of pulvis shape according to proportioning;
The pulvis that above-mentioned steps one, two is obtained mixes, and then stirs evenly, namely obtains in 60 ℃ of lower drying under reduced pressure Celsius, sterilization, packing the Chinese herbal feed additive of described raising immunity.
By above-mentioned preparation method, every part of 50 grams.
Beneficial effect:
The present invention's Chinese herbal medicine used is cheap common drug, being made into animal feed additive takes, replace the use of antibiotic and medicine, both without any side effects, can obviously improve the physique of animal again, such as piglet, chicken and duck etc. obtained higher economic benefit with lower input, also antibiotic-free and chemicals are residual, and in the animality goods, antibiotic residue provides effective way in order to reduce.The medicament that natural Chinese medicinal herb is formed can be built up health as the feed addictive feeding animals, improves immunity of organisms, to strengthening communicable disease, invasive organism and parasitic resistance and improving meat and output has remarkable effect.
Specific embodiment
Embodiment 1
Lythrum salicaria claims again water branch willow, water willow, Purple Loosestrife.The Lythraceae Lythrum.Perennial very this plant of pasture and water.1 meter left and right of plant height, stem four prismatics, upright multi-branched, leaf is to life or verticillate, lanceolar.Give birth on long spike top, and Xiao Hua is many and close, aubergine, and Xia Qiu is bloomed.Naturally plant and grow on marshland, irrigation canals and ditches limit or beach.Happiness light, moistening, draughty environment, Salt And Alkali Tolerance, growth result is better in fertile, loose soil.Complete stool can be used as medicine, and can control the diseases such as dysentery, enteritis; Another tool trauma hemostasis effect.Herb contains salicarin (Salicarin), tannin.In ash content, sodium is one times of potassium, and contains volume iron, choline 0.026%.Tannin master is the gallic acid tannin, and its content is: root 8.5%, and stem 10.5%, leaf 12% spends 13.7%, and seed also contains a large amount of tannins.Flower contains flavone compound Vitexin (Vitexin), orientin (Orientin), malvin (Malvin is Malvidin3,5-diglucoside), Cyanidin galactoside (Cyanidin3-monogalactoside), gallic acid, benzoaric acid (Ellagicacid) and a small amount of chlorogenic acid (Chlorogenicacid).Contain Vitexin (vitexin), orientin (orientin), homo-orientin (isoorientin, homoorientin), chlorogenic acid, ellagic acid and gallic acid, still contain choline, tannin and pigment.And contain a small amount of volatile oil, pectin, resin and alkaloid.
Red back of the body dish has another name called kwan-yin dish, Radix Angelicae Sinensis dish, red phoenix dish, kwan-yin amaranth, red back of the body dish, gynura bicolor.Feverfew.Like being grown in dark moist place.The bottom surface of leaf is green, and the back side is aubergine, is called " red back of the body dish ".It helps reducing blood lipid, and is hypoglycemic, aid digestion, changes intestines gas.The edible wild herbs that to taste throughout the year.Modern medicine proves, red back of the body dish not only contains the abundant ferro element with hematopoiesis function, and be rich in provitamin A, red back of the body dish flavone compound and as activator manganese element of enzyme etc., long-term edible this Lay can play and enrich blood, suppress the malignancy cell, reduce the effects such as blood vessel purpura, for the needs person of enriching blood, tumor patient, be subjected to the crowd of pelvic infecton, bronchitis, arterial sclerosis puzzlement etc., can play the booster action of dietotherapy, it also has anti parasitic and antiviral effect simultaneously, strengthens the immunocompetence of human body.The cauline leaf quality softness of red back of the body dish is soft, has flavour when edible, and also the Yin Qiye look is special and the Chang Zuowei landscape plant uses, and has higher medical value.
Chinese yam, the common name Chinese yam.Herbaceos perennial, stem is overgrow, and often is with purple, and the piece root is cylindrical, and leaf is to life, and is avette or oval, flower milky, dioecism.Starch-containing and the protein of piece root.Chinese yam-medicinal part, plant name: Chinese yam (y ù), the Latin language formal name used at school: Dioscorea opposita another name: Chinese yam, triangle, RHIIZOMA DIOSCOREAE from Henan of China, Chinese yam rhizome, medicine egg, native potato, mountain potato, jade prolong.Smell: (root) is sweet, warm, flat, nontoxic.English name: nagaimo, yamaimo, Chinese yam, Japanese mountain yam, Korean yam; Compendium of Materia Medica " record, Chinese yam is because the Tang Dynasty ancestor is Li Yu, for taboo changes the potato medicine into, again because Song Yingzong is Zhao Shu, for taboo changes Chinese yam into.Chinese yam is one of composition medicine of Liuwei Dihuang Wan.[1] Chinese yam " book on Chinese herbal medicine is looked for the truth ": " enter in drugs for nourishing yin to give birth to use, entering tonifying spleen lung medicine should use by stir-bake to yellowish." " this genus food, flat though gas is warm, be the moon of tonifying spleen lung.Can moisten fur, longue meat, distinguish the flavor of sweet hold concurrently salty, again can the kidney-nourishing reinforcing yin essence.", in the research of C-II induced arthritis in rats, Chinese yam water extraction liquid can significantly suppress Cu2+ to the denaturation of gamma Globulin, shows to have antarthritic effect.Chinese yam water extraction liquid also can be eliminated urine albumen, mutant cell is had the effect that suppresses generation.Tonifying middle-Jiao and Qi: iron rod yam is planted trace element because being rich in 18 seed amino acids and more than 10, and other mineral matter, so strengthening the spleen and stomach, tonifying lung kidney, tonifying middle-Jiao and Qi, invigorating the spleen qi-restoratives are arranged, the effects such as beneficial essence, beneficial heart and tranquilizing mind of reinforcing the kidney, saying of " all kinds of diseases and ailments are reinforced the kidney, controlled to invigorating the spleen help, taste essence, treats general debility " arranged in the Li Shizhen (1518-1593 A.D.) Compendium of Material Medica.Quench one's thirst and promote the production of body fluid: this Chinese yam has the effect of the life of quenching one's thirst: the Chinese traditional treatment consumptive disease is quenched one's thirst often has the Chinese yam single to use in (diabetes) prescription, or share with other medicines, and effect is better.Health care: because bright Chinese yam is rich in multivitamin, amino acid and mineral matter, can prevent and treat Human Lipid Metabolism abnormal, and artery sclerosis, to safeguarding that the insulin normal function also has certain effect, the enhancing body immunity is arranged, beneficial heart and tranquilizing mind, rather cough Dingchuan, the health-care effect such as delay senility.Beauty treatment: Yuan Dynasty taste expert Li Gao says: " control dry skin and moisten it with this thing." Li Shizhen (1518-1593 A.D.) is write: " Chinese yam can be moistened fur." Chinese yam is to nourishes rough skin, and vigorous and graceful beauty treatment has unique curative effect.
the present invention is evil according to traditional Chinese medical science righting Eradicates theoretical, follow and replenish qi to invigorate the spleen, the positive dampness elimination fundamentum of temperature, the selection of other Chinese medicinal ingredients is after checking for many years, record and test gained, although their effect is different, but choosing of each Chinese medicine is not to be arbitrarily, the applicant is according to the proportioning of for many years each composition of test gained, it is not the raw material effect simple superposition with each composition, because may have interpromoting relation in five elements between various Chinese medicine materials, mutual reinforcement between, the multiple interactively such as mutual restraint between two drugs or the mutual-detoxication, and the applicant has selected above-mentioned raw materials accordingly according to this principle exactly, and determined the best proportioning between them, therefore, the application has significant meaning.
Other Chinese medicinal ingredients that relate to are through verifying for many years, put down in writing and test gained, although their effect is different, choosing of each Chinese medicine is not to be arbitrarily that length is limit, and does not carry out exhaustive at this;
a kind of Chinese herbal feed additive that improves immunity, it is characterized in that, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
a kind of Chinese herbal feed additive that improves immunity, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 3 parts, Fructus Hordei Germinatus, 1 part of calcium monohydrogen phosphate, be 1 part of gustin, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 5 parts of stone flours, 1 part of Potassiumiodate, 5 parts of VBTs, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme, 1~5 part, nucleotides, 1~3 part of staphylococcus lysozyme, 1~3 part of methionine, 1~2 part, folic acid, β-1~2 part of calabash radish element, 1~3 part of acidulant.
The feed that a kind of Chinese herbal feed additive that improves immunity is made, described acidulant is that acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
A kind of method that Chinese herbal feed additive that improves immunity is made is characterized in that step is as follows:
1) select commercially available micronizer;
2) take 10~30 parts of the Lythrum salicarves of respective amount according to a handling capacity of micronizer, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
Step 1, take above-mentioned each composition by said ratio, be Lythrum salicaria, red back of the body dish, Chinese yam, barrenwort, stir-baked MASSA FERMENTATA MEDICI-NALIS, reticulate millettia, the root of kudzu vine, rattletop, Chinese herbaceous peony, build song, rheum officinale, the bark of official magnolia, rhizome of cyrtomium, Radix Glycyrrhizae, the root of large-flowered skullcap, caulis lonicerae, gynostemma pentaphylla, Poria cocos, by micronizer, make superfine powder to 200 order after pulverizing stand-by; Described Lythrum salicaria, red back of the body dish are root, cauline leaf, the flower below 9wt% with dried water content, are placed in the frying pot in 130~150 ℃ of fryings 10 minutes, until till the jaundice of surface, namely take out standby;
Step 2, take isoflavones, soyasaponins and the described supplementary element of pulvis shape according to proportioning;
The pulvis that above-mentioned steps one, two is obtained mixes, and then stirs evenly, namely obtains in 60 ℃ of lower drying under reduced pressure Celsius, sterilization, packing the Chinese herbal feed additive of described raising immunity.
By above-mentioned preparation method, every part of 50 grams.
Pharmacological evaluation Comparative Examples: 1, test daily ration
(1) select a, b, c, four groups of breast complete feed for piglets of d, wherein a is premix provided by the invention; B, c, d premix is different from a premix is that micro-kind and content there are differences, and b premix is used is glycine series trace element, and c, d premix are used is inorganic microelement.
(2) above-mentioned premix is prepared respectively obtain A, B, C, four kinds of daily rations of D, wherein the daily ration of A for using premix provided by the invention to be mixed with.
Major Nutrient level such as the following table of A, B, C, four groups of daily rations of D:
Table 1
Figure BSA00000860886700071
Figure BSA00000860886700081
2, piglet grouping and feeding and management
Test is carried out on P1, P2, P3 three pig farms, and totally 42 of P1 pig farm piglets are divided into T1, two processed group of T2, and 21 every group, 3 repetitions of every processing, each natural feeding circle is 1 repetition, 7, every circle.Raise in the semi-hermetic type pig house, use respectively above-mentioned A, two kinds of diet feedings of B 33 days.Totally 72 of P2 pig farm piglets are divided into T1, two processed group of T2, and 36 every group, 3 repetitions of every processing, each repeats 12.Raise in the semi-hermetic type pig house, use respectively above-mentioned A, two kinds of diet feedings of C 10 days.Totally 96 of P3 pig farm piglets are divided into T1, two processed group of T2, and 48 every group, 3 repetitions of every processing, each repeats 16.Raise in the semi-hermetic type pig house, use respectively above-mentioned A, two kinds of diet feedings of D 14 days.Piglet free choice feeding and drinking-water, health in cleaning sterilization every day house is rinsed water fountain.By normal immune programme for children immunity.Every day by special messenger's observed and recorded test piglet search for food, grow, the situations such as diarrhoea and daily behavior.
3, index detects
Daily gain, feed intake and feedstuff-meat ratio: when on-test and off-test respectively at morning 8:00 weigh on an empty stomach; Carry out ramming material when weighing, the statistics feed intake; Calculate average daily gain and the feedstuff-meat ratio of experimental period piglet.
4, data are processed
Test data employing SPSS10.0 statistical software adds up, and carries out variance analysis and Duncan ' s multiple ratio.The significance level of difference is set: P<0.05 is significant difference, and P<0.01 is that difference is extremely remarkable.
5, result
Production performance: P1, P2, P3 pig farm is at piglet stage feed respectively A, B, C, four kinds of daily rations of D, on the weaned piglets impact as following table:
Table 2
? T1 (A daily ration) T2 (B daily ration) T1/T2
Initial weight (kg) 7.85 7.2 -
Number (head) 21 20 (one of Deaths) -
Search for food day (kg) 1.03 1.03 -
Daily gain (g) 540 a 470 b +14.89%
Feedstuff-meat ratio 1.92∶1 a 2.21∶1 b -13.12%
Table 3
? T1 (A daily ration) T2 (C daily ration) T1/T2
Initial weight (kg) 6.35 6.35 -
Number (head) 36 36 -
Search for food day (g) 268.7 239.7 +12.10%
Daily gain (g) 243 a 196.4 b +23.73%
Feedstuff-meat ratio 1.11∶1 a 1.22∶1 b -9.02%
Table 4
? T1 (A daily ration) T2 (D daily ration) T1/T2
Initial weight (kg) 6.36 6.36 -
Number (head) 48 48 -
Daily gain (g) 230 a 200 b +15%
Feedstuff-meat ratio 1.56∶1 a 1.73∶1 b -10.9%
Annotate: the same person of colleague's shoulder marking-up parent phase, difference is not remarkable; Difference person's significant difference (P<0.05).
The daily gain of different disposal group, feed intake, feedstuff-meat ratio show: in the piglet stage, added the daily ration A group of premix of the present invention and compared with feed daily ration B, C, D group, daily gain and feedstuff-meat ratio all significantly improve (P<0.05).A daily ration group is compared with B daily ration group, and daily gain can improve 14.89%, and feedstuff-meat ratio can reduce by 13.12%; A daily ration group is compared with C daily ration group, and daily gain can improve 12.10%, and feedstuff-meat ratio can reduce by 9.02%; A daily ration group is compared with D daily ration group, and daily gain can improve 15%, and feedstuff-meat ratio can reduce by 10.9%.
Show through pharmacological testing: be made into animal feed additive and take, replace the use of antibiotic and medicine, both without any side effects, can obviously improve the physique of animal again, such as piglet, chicken and duck etc., obtain higher economic benefit with lower input, go back antibiotic-free and chemicals is residual, in the animality goods, antibiotic residue provides effective way in order to reduce.
The raw material of this product all takes full advantage of the resource of artificial growth, and its raw material resources abundance is guaranteed, and production cost is low, efficient is high, economic benefit, social benefit are remarkable.
Embodiment 2
a kind of Chinese herbal feed additive that improves immunity, it is characterized in that, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
a kind of Chinese herbal feed additive that improves immunity, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 3 parts, Fructus Hordei Germinatus, 1 part of calcium monohydrogen phosphate, be 1 part of gustin, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 5 parts of stone flours, 1 part of Potassiumiodate, 5 parts of VBTs, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme, 1~5 part, nucleotides, 1~3 part of staphylococcus lysozyme, 1~3 part of methionine, 1~2 part, folic acid, β-1~2 part of calabash radish element, 1~3 part of acidulant.
The feed that a kind of Chinese herbal feed additive that improves immunity is made, described acidulant is that acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
A kind of method that Chinese herbal feed additive that improves immunity is made is characterized in that step is as follows:
1) select commercially available micronizer;
2) take 10~30 parts of the Lythrum salicarves of respective amount according to a handling capacity of micronizer, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
Step 1, take above-mentioned each composition by said ratio, be Lythrum salicaria, red back of the body dish, Chinese yam, barrenwort, stir-baked MASSA FERMENTATA MEDICI-NALIS, reticulate millettia, the root of kudzu vine, rattletop, Chinese herbaceous peony, build song, rheum officinale, the bark of official magnolia, rhizome of cyrtomium, Radix Glycyrrhizae, the root of large-flowered skullcap, caulis lonicerae, gynostemma pentaphylla, Poria cocos, by micronizer, make superfine powder to 200 order after pulverizing stand-by; Described Lythrum salicaria, red back of the body dish are root, cauline leaf, the flower below 9wt% with dried water content, are placed in the frying pot in 130~150 ℃ of fryings 10 minutes, until till the jaundice of surface, namely take out standby;
Step 2, take isoflavones, soyasaponins and the described supplementary element of pulvis shape according to proportioning;
The pulvis that above-mentioned steps one, two is obtained mixes, and then stirs evenly, namely obtains in 60 ℃ of lower drying under reduced pressure Celsius, sterilization, packing the Chinese herbal feed additive of described raising immunity.
By above-mentioned preparation method, every part of 50 grams.
Additive product in the embodiment of the present invention 2 and conventional feed additive (additive of Henan chemical industry in morning feed addictive factory is selected in this experiment) are compared test, and test arrangement is specific as follows:
Materials and methods
1, experimental animal
Selecting body weight is 9kg (± 0.5kg) Du * length * Dasanyuan hybridization market pig.
Date of test, place
On January 2nd, 2012 is to January 27 in cooperation pig farm, Shandong.
2, experimental design and daily ration
The single-factor design is adopted in this test, with 60 body weight 9kg (± 0.5kg) Du * length * Dasanyuan is hybridized market pig and is divided at random 2 processed group, 3 repetitions of each processed group, each repeats 10 pigs.Additive, the test group of control group fed Henan chemical industry in morning feed addictive factory embodiment 1 product of feeding continues 25 days.
3, feeding and management
Feed intake, add the feedings and managements such as water, dosing, epidemic prevention according to the normal schedule in this pig farm.
4, testing index
Measure diarrhea rate, the death rate, daily gain and feedstuff-meat ratio index.
5, result of the test
Result of the test sees the following form 1:
Table 5
Project Control group Test group
Diarrhoeal diseases incidence (%) 6.72±0.79 3.87±0.64
The death rate (%) 5.48±1.69 4.58±0.96
Daily gain (g) 539±28.62 584±35.12
Feedstuff-meat ratio 1.45 ± 0.061.36 ± 0.04
As seen, the diarrhoeal diseases incidence has descended 2.85%; Death rate test group has descended 0.9% than control group; The daily gain test group has improved 45g than control group; The feedstuff-meat ratio test group has reduced by 0.09 than control group.
Show through pharmacological testing: be made into animal feed additive and take, replace the use of antibiotic and medicine, both without any side effects, can obviously improve the physique of animal again, such as piglet, chicken and duck etc., obtain higher economic benefit with lower input, go back antibiotic-free and chemicals is residual, in the animality goods, antibiotic residue provides effective way in order to reduce.
The raw material of this product all takes full advantage of the resource of artificial growth, and its raw material resources abundance is guaranteed, and production cost is low, efficient is high, economic benefit, social benefit are remarkable.
Embodiment 3
a kind of Chinese herbal feed additive that improves immunity, it is characterized in that, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
a kind of Chinese herbal feed additive that improves immunity, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 3 parts, Fructus Hordei Germinatus, 1 part of calcium monohydrogen phosphate, be 1 part of gustin, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10 parts of Lythrum salicarves, 10 parts of red back of the body dishes, 5 parts of Chinese yams, 15 parts of barrenwort, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10 parts of reticulate millettias, 10 parts of the roots of kudzu vine, 10 parts of rattletops, 10 parts of Chinese herbaceous peonies, build bent 4 parts, 4 parts of rheum officinales, 2 parts of the barks of official magnolia, 2 parts of rhizome of cyrtomium, 3 parts, Radix Glycyrrhizae, 5 parts of the roots of large-flowered skullcap, 5 parts of caulis loniceraes, 2 parts of gynostemma pentaphylla, 2 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100 parts of corns, 50 parts, wheat bran, 30 parts of palm kernel meals, 1 part of fish meal, 5 parts of salt, 5 parts of stone flours, 1 part of Potassiumiodate, 5 parts of VBTs, 0.5 part of lysozyme.
the feed that a kind of Chinese herbal feed additive that improves immunity is made, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme, 1~5 part, nucleotides, 1~3 part of staphylococcus lysozyme, 1~3 part of methionine, 1~2 part, folic acid, β-1~2 part of calabash radish element, 1~3 part of acidulant.
The feed that a kind of Chinese herbal feed additive that improves immunity is made, described acidulant is that acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
A kind of method that Chinese herbal feed additive that improves immunity is made is characterized in that step is as follows:
1) select commercially available micronizer;
2) take 10~30 parts of the Lythrum salicarves of respective amount according to a handling capacity of micronizer, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
Step 1, take above-mentioned each composition by said ratio, be Lythrum salicaria, red back of the body dish, Chinese yam, barrenwort, stir-baked MASSA FERMENTATA MEDICI-NALIS, reticulate millettia, the root of kudzu vine, rattletop, Chinese herbaceous peony, build song, rheum officinale, the bark of official magnolia, rhizome of cyrtomium, Radix Glycyrrhizae, the root of large-flowered skullcap, caulis lonicerae, gynostemma pentaphylla, Poria cocos, by micronizer, make superfine powder to 200 order after pulverizing stand-by; Described Lythrum salicaria, red back of the body dish are root, cauline leaf, the flower below 9wt% with dried water content, are placed in the frying pot in 130~150 ℃ of fryings 10 minutes, until till the jaundice of surface, namely take out standby;
Step 2, take isoflavones, soyasaponins and the described supplementary element of pulvis shape according to proportioning;
The pulvis that above-mentioned steps one, two is obtained mixes, and then stirs evenly, namely obtains in 60 ℃ of lower drying under reduced pressure Celsius, sterilization, packing the Chinese herbal feed additive of described raising immunity.
By above-mentioned preparation method, every part of 50 grams.
Additive product in the embodiment of the present invention 3 and conventional feed additive (additive of Henan chemical industry in morning feed addictive factory is selected in this experiment) are compared test, and test arrangement is specific as follows:
Materials and methods
1, experimental animal
Selecting body weight is 9kg (± 0.5kg) Du * length * Dasanyuan hybridization market pig.
Date of test, place
On January 2nd, 2012 is to January 27 in cooperation pig farm, Shandong Province.
2, experimental design and daily ration
The single-factor design is adopted in this test, with 60 body weight 9kg (± 0.5kg) Du * length * Dasanyuan is hybridized market pig and is divided at random 2 processed group, 3 repetitions of each processed group, each repeats 10 pigs.Additive, the test group of control group fed Henan chemical industry in morning feed addictive factory embodiment 1 product of feeding continues 25 days.
3, feeding and management
Feed intake, add the feedings and managements such as water, dosing, epidemic prevention according to the normal schedule in this pig farm.
4, testing index
Measure diarrhea rate, the death rate, daily gain and feedstuff-meat ratio index.
5, result of the test
Result of the test sees the following form 1:
Table 6
Project Control group Test group
Diarrhoeal diseases incidence (%) 6.73±0.79 3.87±0.64
The death rate (%) 5.49±1.69 4.58±0.96
Daily gain (g) 539±28.62 584±35.12
Feedstuff-meat ratio 1.45 ± 0.061.36 ± 0.04
As seen, the diarrhoeal diseases incidence has descended 2.85%; Death rate test group has descended 0.9% than control group; The daily gain test group has improved 45g than control group; The feedstuff-meat ratio test group has reduced by 0.09 than control group.
Show through pharmacological testing: be made into animal feed additive and take, replace the use of antibiotic and medicine, both without any side effects, can obviously improve the physique of animal again, such as piglet, chicken and duck etc., obtain higher economic benefit with lower input, go back antibiotic-free and chemicals is residual, in the animality goods, antibiotic residue provides effective way in order to reduce.
This explanation be that the number range that relates in embodiment is all through the many experiments gained, each point can be realized, is not confined to end points or terminal point, length is limit, and does not enumerate at this.
It should be noted that at last: above embodiment only in order to technical scheme of the present invention to be described, is not intended to limit; Although with reference to previous embodiment, the present invention is had been described in detail, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme that aforementioned each embodiment puts down in writing, and perhaps part technical characterictic wherein is equal to replacement; And these modifications or replacement do not make the essence of appropriate technical solution break away from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (7)

1. Chinese herbal feed additive that improves immunity, it is characterized in that, its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins.10 parts of supplementary elements, described supplementary element are vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, and each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
2. a kind of Chinese herbal feed additive that improves immunity as described in claim 1, it is characterized in that: its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 3~5 parts, Fructus Hordei Germinatus, 1~3 part of calcium monohydrogen phosphate, be 1~3 part of gustin, 0.15 part of isoflavones, 1.5 parts of soyasaponins.10 parts of supplementary elements, described supplementary element are vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, and each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
3. the feed made of a kind of Chinese herbal feed additive that improves immunity as described in claim 1, it is characterized in that: its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins.10 parts of supplementary elements, described supplementary element are vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, and each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1;
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 0.5~8 part of lysozyme.
4. the feed made of a kind of Chinese herbal feed additive that improves immunity as described in claim 1, it is characterized in that: its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme.
5. a kind of described in claim 1-4 improves the feed that the Chinese herbal feed additive of immunity is made, it is characterized in that: its constituent and parts by weight are: 10~30 parts of Lythrum salicarves, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1,
100~300 parts of corns, 50~150 parts, wheat bran, 30~50 parts of palm kernel meals, 1~50 part of fish meal, 5~10 parts of salt, 5~10 parts of stone flours, 1~5 part of Potassiumiodate, 5~10 parts of VBTs, 0.5~8 part of lysozyme, 1~5 part, nucleotides, 1~3 part of staphylococcus lysozyme, 1~3 part of methionine, 1~2 part, folic acid, β-1~2 part of calabash radish element, 1~3 part of acidulant.
6. the feed made of a kind of Chinese herbal feed additive that improves immunity as described in claim 5, it is characterized in that: described acidulant is that acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
7. a kind of Chinese herbal feed additive that improves immunity method of making as described in claim 1 is characterized in that step is as follows:
1) select commercially available micronizer;
2) take 10~30 parts of the Lythrum salicarves of respective amount according to a handling capacity of micronizer, 10~20 parts of red back of the body dishes, 5~10 parts of Chinese yams, 15~35 parts of barrenwort, 10~20 parts of stir-baked MASSA FERMENTATA MEDICI-NALISs, 10~20 parts of reticulate millettias, 10~20 parts of the roots of kudzu vine, 10~15 parts of rattletops, 10~15 parts of Chinese herbaceous peonies, build bent 4~8 parts, 4~8 parts of rheum officinales, 2~5 parts of the barks of official magnolia, 2~5 parts of rhizome of cyrtomium, 3~10 parts, Radix Glycyrrhizae, 5~8 parts of the roots of large-flowered skullcap, 5~8 parts of caulis loniceraes, 2~5 parts of gynostemma pentaphylla, 2~5 parts, Poria cocos, 0.15 part of isoflavones, 1.5 parts of soyasaponins, 10 parts of supplementary elements, described supplementary element is vitamin A, Cobastab, vitamin C, chromium trichloride, yellow first glue, xylitol, crystallization of mannitol, each part proportioning of described supplementary element is 0.2: 0.2: 0.5: 0.3: 1: 1: 1.
Step 1, take above-mentioned each composition by said ratio, be Lythrum salicaria, red back of the body dish, Chinese yam, barrenwort, stir-baked MASSA FERMENTATA MEDICI-NALIS, reticulate millettia, the root of kudzu vine, rattletop, Chinese herbaceous peony, build song, rheum officinale, the bark of official magnolia, rhizome of cyrtomium, Radix Glycyrrhizae, the root of large-flowered skullcap, caulis lonicerae, gynostemma pentaphylla, Poria cocos, by micronizer, make superfine powder to 200 order after pulverizing stand-by; Described Lythrum salicaria, red back of the body dish are root, cauline leaf, the flower below 9wt% with dried water content, are placed in the frying pot in 130~150 ℃ of fryings 10 minutes, until till the jaundice of surface, namely take out standby;
Step 2, take isoflavones, soyasaponins and the described supplementary element of pulvis shape according to proportioning;
The pulvis that above-mentioned steps one, two is obtained mixes, and then stirs evenly, namely obtains in 60 ℃ of lower drying under reduced pressure Celsius, sterilization, packing the Chinese herbal feed additive of described raising immunity.
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