CN103012344B - 从洛伐他汀结晶母液中回收洛伐他汀的方法 - Google Patents
从洛伐他汀结晶母液中回收洛伐他汀的方法 Download PDFInfo
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- CN103012344B CN103012344B CN201110295637.4A CN201110295637A CN103012344B CN 103012344 B CN103012344 B CN 103012344B CN 201110295637 A CN201110295637 A CN 201110295637A CN 103012344 B CN103012344 B CN 103012344B
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- lovastatin
- solution
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- crystalline mother
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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Priority Applications (1)
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CN201110295637.4A CN103012344B (zh) | 2011-09-28 | 2011-09-28 | 从洛伐他汀结晶母液中回收洛伐他汀的方法 |
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CN201110295637.4A CN103012344B (zh) | 2011-09-28 | 2011-09-28 | 从洛伐他汀结晶母液中回收洛伐他汀的方法 |
Publications (2)
Publication Number | Publication Date |
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CN103012344A CN103012344A (zh) | 2013-04-03 |
CN103012344B true CN103012344B (zh) | 2014-11-12 |
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CN201110295637.4A Expired - Fee Related CN103012344B (zh) | 2011-09-28 | 2011-09-28 | 从洛伐他汀结晶母液中回收洛伐他汀的方法 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104341377B (zh) * | 2013-08-05 | 2016-10-19 | 北大方正集团有限公司 | 从洛伐他汀结晶母液中回收洛伐他汀的方法 |
CN108239056B (zh) * | 2016-12-26 | 2020-06-23 | 北大方正集团有限公司 | 一种从美伐他汀结晶母液中回收美伐他汀的方法 |
CN108976190B (zh) * | 2017-12-21 | 2020-09-04 | 北大方正集团有限公司 | 一种从洛伐他汀结晶母液中回收洛伐他汀的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0033536A2 (en) * | 1980-02-04 | 1981-08-12 | Merck & Co. Inc. | 6(R)-(2-(8'-etherified-hydroxy-2',6'-dimethylpolyhydro-naphthyl-1')-ethyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones, the hydroxy acid form of said pyranones, the salts of said acid form, process for preparing the same and an antihypercholesterolemic pharmaceutical composition containing the same |
WO1997020834A1 (en) * | 1995-12-06 | 1997-06-12 | Antibiotic Co. | Method of production of lovastatin |
WO2000063411A1 (en) * | 1999-04-16 | 2000-10-26 | Biotika A.S. | Process of isolation of lovastatin from fermentation broth |
CN1583736A (zh) * | 2004-06-03 | 2005-02-23 | 山东鲁抗医药股份有限公司 | 洛伐他汀的提取精制方法 |
-
2011
- 2011-09-28 CN CN201110295637.4A patent/CN103012344B/zh not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0033536A2 (en) * | 1980-02-04 | 1981-08-12 | Merck & Co. Inc. | 6(R)-(2-(8'-etherified-hydroxy-2',6'-dimethylpolyhydro-naphthyl-1')-ethyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones, the hydroxy acid form of said pyranones, the salts of said acid form, process for preparing the same and an antihypercholesterolemic pharmaceutical composition containing the same |
WO1997020834A1 (en) * | 1995-12-06 | 1997-06-12 | Antibiotic Co. | Method of production of lovastatin |
WO2000063411A1 (en) * | 1999-04-16 | 2000-10-26 | Biotika A.S. | Process of isolation of lovastatin from fermentation broth |
CN1583736A (zh) * | 2004-06-03 | 2005-02-23 | 山东鲁抗医药股份有限公司 | 洛伐他汀的提取精制方法 |
Non-Patent Citations (2)
Title |
---|
洛伐他汀母液回收工艺研究;王健 等;《河北工业科技》;20090930;第26卷(第5期);第394-395页 * |
王健 等.洛伐他汀母液回收工艺研究.《河北工业科技》.2009,第26卷(第5期), * |
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CN103012344A (zh) | 2013-04-03 |
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Address after: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee after: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee after: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. Patentee after: PKU HEALTHCARE INDUSTRY Group Address before: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: Peking University International Hospital Group Chongqing Daxin Pharmaceutical Co.,Ltd. Patentee before: Pku Healthcare Industry Group Co.,Ltd. |
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Effective date of registration: 20221014 Address after: 3007, Hengqin international financial center building, No. 58, Huajin street, Hengqin new area, Zhuhai, Guangdong 519031 Patentee after: New founder holdings development Co.,Ltd. Patentee after: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. Patentee after: Peking University Medical Management Co.,Ltd. Address before: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: CHONGQING DAXIN PHARMACEUTICAL Co.,Ltd. Patentee before: PKU HEALTHCARE INDUSTRY Group |
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Granted publication date: 20141112 |