CN103006346A - Spinal cord injury percussion apparatus - Google Patents
Spinal cord injury percussion apparatus Download PDFInfo
- Publication number
- CN103006346A CN103006346A CN2012105930402A CN201210593040A CN103006346A CN 103006346 A CN103006346 A CN 103006346A CN 2012105930402 A CN2012105930402 A CN 2012105930402A CN 201210593040 A CN201210593040 A CN 201210593040A CN 103006346 A CN103006346 A CN 103006346A
- Authority
- CN
- China
- Prior art keywords
- spinal cord
- motion platform
- line slideway
- timing belt
- knocking gear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009527 percussion Methods 0.000 title claims abstract description 19
- 208000020431 spinal cord injury Diseases 0.000 title claims abstract description 18
- 210000000278 spinal cord Anatomy 0.000 claims abstract description 63
- 230000007246 mechanism Effects 0.000 claims abstract description 62
- 238000002474 experimental method Methods 0.000 claims abstract description 35
- 238000006073 displacement reaction Methods 0.000 claims abstract description 16
- 230000006378 damage Effects 0.000 claims abstract description 15
- 238000010171 animal model Methods 0.000 claims abstract description 9
- 241001465754 Metazoa Species 0.000 claims description 14
- 230000001360 synchronised effect Effects 0.000 claims description 8
- 230000001105 regulatory effect Effects 0.000 claims description 6
- 239000003638 chemical reducing agent Substances 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 4
- 208000034656 Contusions Diseases 0.000 abstract description 5
- 230000009519 contusion Effects 0.000 abstract description 5
- 238000004088 simulation Methods 0.000 abstract description 5
- 208000027418 Wounds and injury Diseases 0.000 abstract 2
- 208000014674 injury Diseases 0.000 abstract 2
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 5
- 210000001951 dura mater Anatomy 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000002085 persistent effect Effects 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000000011 invertebrate ventral nerve cord Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
Images
Abstract
The invention discloses a ventral spinal cord injury percussion apparatus, which can perform a percussion experiment on ventral spinal cord of an experimental animal object to cause corresponding degree of injury to ventral spinal cord. The apparatus comprises an XY motion platform, a Z adjustment mechanism, a spinal cord percussion mechanism and a connecting mechanism, wherein the XY motion platform is used for fixing the experimental animal object and adjusting the experimental object on the XOY plane; the spinal percussion mechanism is fixedly mounted on the Z adjustment mechanism, and used for performing a spinal cord percussion injury experiment; and the Z adjustment mechanism is fixed on a baseplate through the connecting mechanism, and used for fixing and adjusting the position of the spinal cord percussion mechanism. According to the device, a more scientific and accurate simulation result of the spinal cord injury experiment can be obtained by using a spinal cord injury model which adopts percussion strength, percussion displacement, percussion duration and spinal cord contusion area as characterizations, and using the curve relationship between position offsets and percussion strengths at every time in the course of a single percussion as an auxiliary illustration.
Description
Technical field
The present invention relates to animal medicine experimental provision field, especially a kind of spinal cord injury percussion device is used for the ventral side of spinal cord of striking experiment animal with simulation the place ahead spinal cord injury.
Background technology
Traditional animal spinal cord damage striking experiment adopts weight (the Weight Dropping that falls usually, WD) method bump spinal cord dorsal part, concrete grammar is that the laboratory animal of anesthesia is carried out the vertebral plate posterior resection, expose but do not destroy spinal dura mater, then the weight block of a known quality is fallen in the mode of freely falling body from certain At The Height, impinge upon on the exposed spinal dura mater of animal spinal column dorsal part, cause the damage to a certain degree of dorsal part spinal cord.Because weight falls acceleration is arranged, but does not tear spinal dura mater, does not cut spinal cord, thereby belongs to dynamic load contusion type.Damage model characterizes with weight quality, the height of fall and contusion of spinal cord area.
The damage location that above-mentioned experimental technique causes is the spinal cord dorsal part, yet the Patients of Spinal majority that causes owing to reasons such as traffic accidents in the daily life is that veutro is impaired, and the weight method of falling can not well be simulated this situation.In order to remedy this deficiency, the experimental provision of the present invention's design can clash into ventral side of spinal cord, cause ventral cord damage to a certain degree, damage model characterizes by bump dynamics, bump displacement, bump persistent period and contusion of spinal cord area, and with in the knockout process each constantly position skew and the curve linear relationship of bump dynamics make aid illustration, thereby obtain more science and accurate spinal cord injury simulation experiment result.
Summary of the invention
The purpose of this invention is to provide a kind of animal spinal cord veutro damage medical experiment device, make this device can automated movement experimental subject and to the quasi experiment knocking gear, simulate afterwards ventral side of spinal cord damage striking experiment and obtain experimental data, the present invention can improve science and the accuracy of animal spinal cord injury experiment effectively.
In order to achieve the above object, technical solution of the present invention provides a kind of spinal cord injury percussion device, and this device comprises: XY motion platform 1, Z guiding mechanism 2, spinal cord knocking gear 3 and bindiny mechanism 4, wherein:
Described XY motion platform 1 is used for fixedly laboratory animal object, and experimental subject is regulated at the enterprising line position of XOY plane, and it comprises: X motion platform 21, Y motion platform 22, base plate 9, top maneuvering board 5, brassboard base plate 6 and brassboard 7; Described Y motion platform 22 is installed on the described base plate 9; Described X motion platform 21 is installed on the slide block of described Y motion platform 22 line slideways and is vertical with described Y motion platform 22; Described top maneuvering board 5 is installed on the slide block of described X motion platform 21 line slideways; Described brassboard base plate 6 is installed on the described top maneuvering board 5; Described brassboard 7 is embedded on the described brassboard base plate 6, and is fixed together with described brassboard base plate 6, is used for fixedly laboratory animal;
Described spinal cord knocking gear 3 is fixedly installed on the described Z guiding mechanism 2, is used for carrying out the experiment of spinal cord impact damage;
Described Z guiding mechanism 2 is fixed on the described base plate 9 by bindiny mechanism 4, is used for position fixing and the described spinal cord knocking gear 3 of adjusting.
The simulating impact experiment is carried out in apparatus of the present invention utilization directly moving electric magnet of releasing, and utilizes micrometer head mechanism to set the displacement of maximum bump, and measures in real time experimental data by micro-force sensor, linear displacement transducer, makes the spinal cord injury experiment realize quantification treatment.Spinal cord injury model characterizes by bump dynamics, bump displacement, bump persistent period and contusion of spinal cord area, and with in the knockout process each constantly position skew and the curve linear relationship of bump dynamics make aid illustration, thereby obtain more science and accurate spinal cord injury simulation experiment result.
Description of drawings
Fig. 1 is structural representation of the present invention;
Fig. 2 a and Fig. 2 b are the structural representations of XY motion platform of the present invention;
Fig. 3 is the structural representation of Z guiding mechanism of the present invention;
Fig. 4 is the structural representation of spinal cord knocking gear of the present invention.
The specific embodiment
For making the purpose, technical solutions and advantages of the present invention clearer, below in conjunction with specific embodiment, and with reference to accompanying drawing, the present invention is described in more detail.
Fig. 1 is the structural representation of the spinal cord injury percussion device that proposes of the present invention, and as shown in Figure 1, described spinal cord injury percussion device comprises: XY motion platform 1, Z guiding mechanism 2, spinal cord knocking gear 3 and bindiny mechanism 4, wherein:
Described XY motion platform 1 is used for fixedly laboratory animal object, and under the acquiescence cartesian coordinate system, experimental subject is regulated at the enterprising line position of XOY plane, it comprises: X motion platform 21, Y motion platform 22, base plate 9, top maneuvering board 5, brassboard base plate 6 and brassboard 7, shown in Fig. 2 a and Fig. 2 b;
The structure of two motion platforms of described X/Y is identical.Take the X motion platform as example, it comprises that respectively direct-drive motor and decelerator 10, motor cabinet 11, Timing Belt 12, synchronous pulley 13, Timing Belt clamp mechanism 14, bearing block 15, Timing Belt backstand 16, line slideway 17, guide rail catch 18, maneuvering board 19, limit switch fixed mechanism 20, wherein:
Described motor cabinet 11 is installed in an end of described maneuvering board 19;
Described direct-drive motor and decelerator 10 are fixed as one and are installed on the described motor cabinet 11, and the output shaft of decelerator passes the interstitial hole of motor cabinet 11;
The drivewheel of described synchronous pulley 13 is installed in the end of reducer output shaft, and the driven pulley of synchronous pulley 13 is installed on the described bearing block 15 by bearing;
The two ends of described Timing Belt 12 respectively with the gear teeth interlock of synchronous pulley 13 drivewheels and driven pulley;
Timing Belt clamps mechanism's 14 1 ends and Timing Belt 12 tight interlocks are fixed together, the other end then with the slide of line slideway 17 be connected mutually (such as passing through screw);
There is protruding key (such as square protruding key) described bearing block 15 both sides, be embedded in the groove of Timing Belt backstand 16, the opposing side of described Timing Belt backstand 16 and this groove is provided with a plurality of screwed holes (such as three), by corresponding screw rod bearing block 15 and described Timing Belt backstand 16 being linked together, and regulate the position of described bearing block 15 by screw rod with the elasticity of control Timing Belt;
Described line slideway 17 and described Timing Belt 12 parallel being installed on the described maneuvering board 19, two ends of described line slideway 17 are separately installed with guide rail catch 18, separate with line slideway to prevent straight-line guide rail slide block;
Described limit switch fixed mechanism 20 is installed on the described maneuvering board 19, and lay respectively at the two ends of described line slideway 17, limit switch then is installed on the described limit switch fixed mechanism 20 and can carries out the position adjustment, to be used for eliminating motion platform processing and alignment error.
Described Y motion platform 22 is installed on the described base plate 9, and parallel with the side of described base plate 9 grooves with handles;
Described X motion platform 21 is installed on the slide block of described Y motion platform 22 line slideways and is vertical with described Y motion platform 22;
Described top maneuvering board 5 is installed on the slide block of described X motion platform 21 line slideways;
The Timing Belt of described Y motion platform 22 is fixed together (such as passing through screw) by the maneuvering board 19 that its Timing Belt clamps mechanism and described X motion platform 21 simultaneously, moves along the respective straight guide rail thereby the Timing Belt of described Y motion platform 22 can drive described X motion platform 21; The Timing Belt of described X motion platform 21 then is fixed together (such as passing through screw) by the bottom that its Timing Belt clamps mechanism 14 and described top maneuvering board 5, moves along corresponding line slideway thereby the Timing Belt of described X motion platform 21 can drive described top maneuvering board 5;
Described brassboard base plate 6 is installed on the described top maneuvering board 5;
Described brassboard 7 is embedded on the described brassboard base plate 6, and four jiaos of described brassboard 7 are left screwed hole, by screw rod described brassboard 7 is fixed together with described brassboard base plate 6, is used for fixedly laboratory animal;
Described spinal cord knocking gear 3 is fixedly installed in (such as passing through bolt) on the described Z guiding mechanism 2, be used for carrying out the experiment of spinal cord impact damage, realize that spinal cord impact damage, the maximum impact damage degree of spinal cord arrange and spacing, bump displacement and bump strength Real-time Measuring amount, obtain science and accurate spinal cord injury simulation experiment result.Described Z guiding mechanism 2 is fixed on the described base plate 9 by bindiny mechanism 4, make it to fix with the relative position of XY motion platform 1, described Z guiding mechanism 2 is used for fixing and regulating the position of described spinal cord knocking gear 3, and particularly fixing and adjusting experiment spinal cord colludes sheet and the position of spinal cord tabletting end on the Z direction.
Fig. 3 is the structural representation of Z guiding mechanism of the present invention, as shown in Figure 3, described Z guiding mechanism 2 comprises: direct-drive motor and decelerator 33, Z motor cabinet 34, gear 32, tooth bar 35, tooth bar fixture 36, line slideway 31, Z track base 39, Z track base backing plate 38, two Z axis angle bar spares 37, two limit switch fixed mechanisms 40 and shells 41, wherein:
Described direct-drive motor and decelerator 33 are installed on the described Z motor cabinet 34, and its reducer output shaft and described gear 32 are connected;
Described Z motor cabinet 34 is installed in the bindiny mechanism shown in Figure 14;
Described Z track base 39 vertically is installed on the described Z motor cabinet 34, and described line slideway 31 is installed in the medial launder of described Z track base 39;
Described tooth bar fixture 36 is installed on the slide block of described line slideway 31, and described spinal cord knocking gear 3 passes described tooth bar fixture 36 by four bolts and also is fixed on the slide block of described line slideway 31;
Described tooth bar 35 is installed on the side of described tooth bar fixture 36 by the screwed hole at its two ends, and meshes together with described gear 32;
The rotation of described gear 32 moves up and down by the slide block that described tooth bar 35 drives described line slideway 31, and then drives the position adjustments that described spinal cord knocking gear 3 carries out on the Z direction;
Described two Z axis angle bar spares 37 are installed on respectively the two ends of described Z track base 39, have respectively four screwed holes on it, are used for being fixedly mounted with described shell 41;
Described Z track base backing plate 38 is installed on the two ends of described Z track base 39, is used for preventing that linear guide slide seat from skidding off;
Described two limit switch fixed mechanisms 40 are installed in respectively on the described two Z axis angle bar spares 37, lay respectively at the up and down two ends of described line slideway 31, limit switch then is installed on respectively on the corresponding limit switch fixed mechanism 40, and its position-adjustable is to eliminate processing and alignment error;
Described shell 41 is installed on the described Z motor cabinet 34.
Fig. 4 is the structural representation of spinal cord knocking gear 3 of the present invention, as shown in Figure 4, described spinal cord knocking gear 3 comprises: knocking gear fixing head 50, the straight moving electric magnet 64 of releasing, electric magnet holder 65, micrometer head 71, micrometer head holder 70, spacing holding screw 68, displacement transducer 69, miniature line slideway 59, micro-force sensor 57, force transducer seat 56, banking stop 66, spacing pole socket 53, gag lever post 51, gag lever post tightening part 52, gag lever post fixture 54, limit spring 67, Z axis Connection Block 55, experiment slide rail 63, experiment slide bar 58, spinal cord tabletting 61, spinal cord colludes sheet 60, holding screw 62, wherein:
In order to make described spinal cord knocking gear 3 and described Z guiding mechanism 2 keep certain interval, four bolts of described knocking gear fixing head 50 usefulness pass the described Z axis Connection Block 55 that is positioned at described knocking gear fixing head 50 rear sides, and the described tooth bar fixture 36 of described Z guiding mechanism 2, finally be fixed on the slide block of line slideway 31 of described Z guiding mechanism 2;
The described straight moving electric magnet 64 of releasing is installed in described knocking gear fixing head 50 lower-left sides by described electric magnet holder 65, and its upper end contacts with the lower end of described banking stop 66 just;
Described miniature line slideway 59 is installed on the lower right side of described knocking gear fixing head 50, and two miniature linear slider are installed on it, and described force transducer seat 56 is installed on the linear slider of upside, and described experiment slide bar 58 is installed on the linear slider of downside;
Between the lower end of described force transducer seat 56, described force transducer seat 56 and the described experiment slide bar 58 described micro-force sensor 57 is installed, the upper end of described force transducer seat 56 is equipped with banking stop 66;
Described displacement transducer 69 is installed in described knocking gear fixing head 50 upper left sides, is positioned at described straight moving electric magnet 64 upper ends of releasing, and described banking stop 66 is fixed together with the sliding bar of described displacement transducer 69;
Described spacing pole socket 53 is installed in the upper right side of described knocking gear fixing head 50, and described gag lever post 51 is embedded in the chute of described spacing pole socket 53;
Described gag lever post tightening part 52, gag lever post fixture 54 are installed on respectively the up and down two ends of described spacing pole socket 53;
One end of described limit spring 67 is fixed on the described gag lever post tightening part 52, the other end is fixed on the described gag lever post 51, is used for control gag lever post 53 and resets;
Described spacing holding screw 68 is installed in the screwed hole of described gag lever post tightening part 52;
Described micrometer head 71 is installed on the top, upper right side of described knocking gear fixing head 50 by described micrometer head holder 70;
Described experiment slide rail 63 is installed in the lower central of described knocking gear fixing head 50;
Described spinal cord tabletting 61 is installed on the side of described experiment slide rail 63 by described holding screw 62;
Described spinal cord colludes sheet 60 and is installed on the described experiment slide bar 58 by described holding screw 62, and its position-adjustable is to eliminate alignment error.
Described bindiny mechanism 4 comprises carrier base 8 and support 72, shown in Fig. 2 (b).Wherein, described carrier base 8 is installed in the rear end of described base plate 9, and is adjacent with described X, Y motion platform; Described support 72 is installed on the described carrier base 8, and the Z motor cabinet 34 of described Z guiding mechanism 3 is installed in the end trough of described support 72 upsides, thereby described Z guiding mechanism 3 and described spinal cord knocking gear 2 are fixed on the described support 72.
The specific works process of spinal cord injury percussion device of the present invention is: during straight moving release electric magnet 64 energising, its output shaft is upwards released fast, and promotion banking stop 66 drives the force transducer seat 56 that is connected with the line slideway upper slider then; Because the micro-force sensor 57 that colludes installation on bar and the force transducer seat 56 of the experiment slide bar 58 that is connected with the line slideway lower slider contacts, thereby experiment slide bar 58 also and then upwards slides in experiment slide rail 63, and then the spinal cord that experiment slide rail 63 lower ends are installed colludes sheet 60 and moves upward fast, the veutro that colludes the experimental subject (animal spinal cord) between the sheet 60 to being positioned over spinal cord tabletting 61 and spinal cord forms bump, and can obtain spinal cord bump data by the signal that reads micro-force sensor 57; When bump occurs, banking stop 66 makes progress fast moving until contact with gag lever post 53, the maximum moving displacement of banking stop 66 is determined by the lower end position of gag lever post 53, and by regulating the upper-lower position of micrometer head 71 adjustable limit bars 53, be the lower end of gag lever post 53 and the distance between the banking stop 66, the lower end position of gag lever post 53 screws spacing holding screw 68 after regulating and finishing, and micrometer head is stressed during with the elimination striking experiment, the protection micrometer head; And the existence of limit spring 67 so that gag lever post 53 can reset; In addition, displacement transducer 69 sliding bar ends are fixed together by screw thread and banking stop 66, thereby measure the real-time displacement that spinal cord knocking gear 3 terminal spinal cords collude sheet 60 by the displacement of measuring banking stop 66; Simultaneously, collude the control that sheet 60 and spinal cord tabletting 61 can realize the spinal cord bump is dampened area by the spinal cord of selecting different size.
Above-described specific embodiment; purpose of the present invention, technical scheme and beneficial effect are further described; institute is understood that; the above only is specific embodiments of the invention; be not limited to the present invention; within the spirit and principles in the present invention all, any modification of making, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. a spinal cord injury percussion device is characterized in that, this device comprises: XY motion platform (1), Z guiding mechanism (2), spinal cord knocking gear (3) and bindiny mechanism (4), wherein:
Described XY motion platform (1) is used for fixedly laboratory animal object, and experimental subject regulated at the enterprising line position of XOY plane, it comprises: X motion platform (21), Y motion platform (22), base plate (9), top maneuvering board (5), brassboard base plate (6) and brassboard (7); Described Y motion platform (22) is installed on the described base plate (9); Described X motion platform (21) is installed on the slide block of described Y motion platform (22) line slideway and is vertical with described Y motion platform (22); Described top maneuvering board (5) is installed on the slide block of described X motion platform (21) line slideway; Described brassboard base plate (6) is installed on the described top maneuvering board (5); Described brassboard (7) is embedded on the described brassboard base plate (6), and is fixed together with described brassboard base plate (6), is used for fixedly laboratory animal;
Described spinal cord knocking gear (3) is fixedly installed on the described Z guiding mechanism (2), is used for carrying out the experiment of spinal cord impact damage;
Described Z guiding mechanism (2) is fixed on the described base plate (9) by bindiny mechanism (4), is used for position fixing and the described spinal cord knocking gear of adjusting (3).
2. device according to claim 1, it is characterized in that, described X motion platform (21) is identical with the structure of Y motion platform (22), include direct-drive motor and decelerator (10), motor cabinet (11), Timing Belt (12), synchronous pulley (13), bearing block (15), Timing Belt backstand (16), line slideway (17), guide rail catch (18), maneuvering board (19), limit switch fixed mechanism (20), wherein:
Described motor cabinet (11) is installed in an end of described maneuvering board (19);
Described direct-drive motor and decelerator (10) are fixed as one and are installed on the described motor cabinet (11), and the output shaft of decelerator passes the interstitial hole of motor cabinet (11);
The drivewheel of described synchronous pulley (13) is installed in the end of reducer output shaft, and the driven pulley of synchronous pulley (13) is installed on the described bearing block (15) by bearing;
The two ends of described Timing Belt (12) respectively with the gear teeth interlock of synchronous pulley (13) drivewheel and driven pulley;
There is protruding key described bearing block (15) both sides, are embedded in the groove of Timing Belt backstand (16), and are fixed together by the opposing side of screw rod and this groove of described Timing Belt backstand (16);
Described line slideway (17) is parallel with described Timing Belt (12) to be installed on the described maneuvering board (19), two ends of described line slideway (17) are separately installed with guide rail catch (18), separate with line slideway to prevent straight-line guide rail slide block;
Described limit switch fixed mechanism (20) is installed on the described maneuvering board (19), and lay respectively at the two ends of described line slideway (17), limit switch then is installed on described limit switch fixed mechanism (20) upward and can carries out the position adjustment, to be used for eliminating motion platform processing and alignment error.
3. device according to claim 2, it is characterized in that, described X motion platform (21) and Y motion platform (22) comprise that also Timing Belt clamps mechanism (14), one end and Timing Belt (12) closely interlock are fixed together, and the other end is connected mutually with the slide of line slideway (17).
4. device according to claim 3, it is characterized in that, the Timing Belt of described Y motion platform (22) is fixed together by the maneuvering board (19) that its Timing Belt clamps mechanism and described X motion platform (21), moves along the respective straight guide rail thereby the Timing Belt of described Y motion platform (22) can drive described X motion platform (21); The Timing Belt of described X motion platform (21) then is fixed together with the bottom of described top maneuvering board (5) by its Timing Belt clamping mechanism (14), moves along corresponding line slideway thereby the Timing Belt of described X motion platform (21) can drive described top maneuvering board (5).
5. device according to claim 1, it is characterized in that, described Z guiding mechanism (2) comprising: direct-drive motor and decelerator (33), Z motor cabinet (34), gear (32), tooth bar (35), tooth bar fixture (36), line slideway (31), Z track base (39), two Z axis angle bar spares (37), two limit switch fixed mechanisms (40) and shell (41), wherein:
Described direct-drive motor and decelerator (33) are installed on the described Z motor cabinet (34), and its reducer output shaft and described gear (32) are connected;
Described Z motor cabinet (34) is installed in the described bindiny mechanism (4);
Described Z track base (39) vertically is installed on the described Z motor cabinet (34), and described line slideway (31) is installed in the medial launder of described Z track base (39);
Described tooth bar fixture (36) is installed on the slide block of described line slideway (31);
Described tooth bar (35) is installed on the side of described tooth bar fixture (36), and meshes together with described gear (32);
The rotation of described gear (32) moves up and down by the slide block that described tooth bar (35) drives described line slideway (31), and then drives described spinal cord knocking gear (3) and carry out position adjustments on the Z direction;
Described two Z axis angle bar spares (37) are installed on respectively the two ends of described Z track base (39);
Described two limit switch fixed mechanisms (40) are installed in respectively on the described two Z axis angle bar spares (37), lay respectively at the up and down two ends of described line slideway (31), limit switch then is installed on respectively on the corresponding limit switch fixed mechanism (40), and its position-adjustable is to eliminate processing and alignment error;
Described shell (41) is installed on the described Z motor cabinet (34).
6. device according to claim 5, it is characterized in that, described Z guiding mechanism (2) also comprises Z track base backing plate (38), and described Z track base backing plate (38) is installed on the two ends of described Z track base (39), is used for preventing that linear guide slide seat from skidding off.
7. device according to claim 1, it is characterized in that, described spinal cord knocking gear (3) comprising: knocking gear fixing head (50), the straight moving electric magnet (64) of releasing, electric magnet holder (65), micrometer head (71), micrometer head holder (70), spacing holding screw (68), displacement transducer (69), miniature line slideway (59), micro-force sensor (57), force transducer seat (56), banking stop (66), spacing pole socket (53), gag lever post (51), gag lever post tightening part (52), gag lever post fixture (54), limit spring (67), Z axis Connection Block (55), experiment slide rail (63), experiment slide bar (58), spinal cord tabletting (61), holding screw (62), wherein:
Described knocking gear fixing head (50) passes the Z axis Connection Block (55) that is positioned at described knocking gear fixing head (50) rear side, the tooth bar fixture (36) of described Z guiding mechanism (2) by bolt, finally is fixed on the slide block of line slideway (31) of described Z guiding mechanism (2);
The described straight moving electric magnet (64) of releasing is installed in described knocking gear fixing head (50) lower-left side by described electric magnet holder (65), and its upper end contacts with the lower end of described banking stop (66) just;
Described miniature line slideway (59) is installed on the lower right side of described knocking gear fixing head (50), two miniature linear slider are installed on it, described force transducer seat (56) is installed on the linear slider of upside, described experiment slide bar (58) is installed on the linear slider of downside;
Between the lower end of described force transducer seat (56), described force transducer seat (56) and the described experiment slide bar (58) described micro-force sensor (57) is installed, the upper end of described force transducer seat (56) is equipped with banking stop (66);
Described displacement transducer (69) is installed in described knocking gear fixing head (50) upper left side, be positioned at described straight moving electric magnet (64) upper end of releasing, described banking stop (66) is fixed together with the sliding bar of described displacement transducer (69);
Described spacing pole socket (53) is installed in the upper right side of described knocking gear fixing head (50), and described gag lever post (51) is embedded in the chute of described spacing pole socket (53);
Described gag lever post tightening part (52), gag lever post fixture (54) are installed on respectively the up and down two ends of described spacing pole socket (53);
One end of described limit spring (67) is fixed on the described gag lever post tightening part (52), and the other end is fixed on the described gag lever post (51), is used for control gag lever post (53) and resets;
Described spacing holding screw (68) is installed in the screwed hole of described gag lever post tightening part (52);
Described micrometer head (71) is installed on the top, upper right side of described knocking gear fixing head (50) by described micrometer head holder (70);
Described experiment slide rail (63) is installed in the lower central of described knocking gear fixing head (50);
Described spinal cord tabletting (61) is installed on the side of described experiment slide rail (63) by described holding screw (62).
8. device according to claim 7, it is characterized in that, described spinal cord knocking gear (3) comprises that also spinal cord colludes sheet (60), described spinal cord colludes sheet (60) and is installed on the described experiment slide bar (58) by described holding screw (62), and its position-adjustable is to eliminate alignment error.
9. device according to claim 1, it is characterized in that described bindiny mechanism (4) comprises carrier base (8) and support (72), wherein, described carrier base (8) is installed in the rear end of described base plate (9), and is adjacent with described X, Y motion platform; Described support (72) is installed on the described carrier base (8).
10. device according to claim 9, it is characterized in that, the Z motor cabinet (34) of described Z guiding mechanism (3) is installed in the end trough of described support (72) upside, thereby described Z guiding mechanism (3) and described spinal cord knocking gear (2) are fixed on the described support (72).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210593040.2A CN103006346B (en) | 2012-12-31 | 2012-12-31 | Spinal cord injury percussion apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210593040.2A CN103006346B (en) | 2012-12-31 | 2012-12-31 | Spinal cord injury percussion apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103006346A true CN103006346A (en) | 2013-04-03 |
| CN103006346B CN103006346B (en) | 2015-04-01 |
Family
ID=47955822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210593040.2A Active CN103006346B (en) | 2012-12-31 | 2012-12-31 | Spinal cord injury percussion apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103006346B (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103505300A (en) * | 2013-09-29 | 2014-01-15 | 四川大学华西医院 | Rat acceleration and deceleration brain trauma striking system |
| CN103989536A (en) * | 2014-04-24 | 2014-08-20 | 中国人民解放军第四军医大学 | Precision mouse spinal cord clamping injury clamp and clamping injury force adjusting method |
| CN104257437A (en) * | 2014-10-20 | 2015-01-07 | 谢杨 | Animal spinal cord injury modeling device |
| CN105796204A (en) * | 2016-05-23 | 2016-07-27 | 戴睿武 | Multifunctional experimental animal impacting machine |
| CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
| CN107837124A (en) * | 2017-12-06 | 2018-03-27 | 中南大学湘雅医院 | A kind of animal model with spinal cord damnification beating device and its operating method |
| CN109009538A (en) * | 2018-08-16 | 2018-12-18 | 新乡医学院第附属医院 | A kind of spinal cord injury simulated experiment percussion device |
| CN109106464A (en) * | 2018-08-14 | 2019-01-01 | 中国人民解放军第四军医大学 | A kind of device and fixed mechanism being used to prepare spinal cord injury experimental model |
| CN109730800A (en) * | 2019-03-15 | 2019-05-10 | 河南医学高等专科学校 | Micro slow positioning injection device is used in a kind of experiment of rat brain |
| CN110680542A (en) * | 2019-08-22 | 2020-01-14 | 无锡市中医医院 | Spinal cord injury striking device |
| CN115024851A (en) * | 2022-08-01 | 2022-09-09 | 暨南大学 | Automatic change spinal cord injury animal model preparation facilities |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185589A (en) * | 2007-12-04 | 2008-05-28 | 中山大学 | Novel electric-controlled multi-use spinal cord beating device |
| CN201112370Y (en) * | 2007-10-12 | 2008-09-10 | 深圳市大族精密机电有限公司 | Two-dimensional motion platform |
| CN101485597A (en) * | 2009-03-03 | 2009-07-22 | 姜树东 | Injury striker for ventral side of spinal cord |
| CN201328880Y (en) * | 2008-11-17 | 2009-10-21 | 徐帆 | Simple model preparer for animals with spinal cord injuries |
| CN201542752U (en) * | 2009-12-15 | 2010-08-11 | 双卫兵 | Experimental facility used for preparing spinal cord injury animal model |
| JP2011005239A (en) * | 2009-05-29 | 2011-01-13 | Atsuki Ijiri | Ventral neck decompression in dog, and implant to be used in ventral neck decompression |
| CN202105043U (en) * | 2011-05-30 | 2012-01-11 | 中国人民解放军第三军医大学 | Device for building spinal cord injury or muscle contusion and laceration animal models |
-
2012
- 2012-12-31 CN CN201210593040.2A patent/CN103006346B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201112370Y (en) * | 2007-10-12 | 2008-09-10 | 深圳市大族精密机电有限公司 | Two-dimensional motion platform |
| CN101185589A (en) * | 2007-12-04 | 2008-05-28 | 中山大学 | Novel electric-controlled multi-use spinal cord beating device |
| CN201328880Y (en) * | 2008-11-17 | 2009-10-21 | 徐帆 | Simple model preparer for animals with spinal cord injuries |
| CN101485597A (en) * | 2009-03-03 | 2009-07-22 | 姜树东 | Injury striker for ventral side of spinal cord |
| JP2011005239A (en) * | 2009-05-29 | 2011-01-13 | Atsuki Ijiri | Ventral neck decompression in dog, and implant to be used in ventral neck decompression |
| CN201542752U (en) * | 2009-12-15 | 2010-08-11 | 双卫兵 | Experimental facility used for preparing spinal cord injury animal model |
| CN202105043U (en) * | 2011-05-30 | 2012-01-11 | 中国人民解放军第三军医大学 | Device for building spinal cord injury or muscle contusion and laceration animal models |
Non-Patent Citations (2)
| Title |
|---|
| KHAN ET AL: "" Animal models of spinal cord contusion injuries"", 《LABORATORY ANIMAL SCIENCE》 * |
| 姜树东 等: ""实验用脊髓腹侧损伤撞击器的设计及应用"", 《中国组织工程研究》 * |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103505300A (en) * | 2013-09-29 | 2014-01-15 | 四川大学华西医院 | Rat acceleration and deceleration brain trauma striking system |
| CN103989536A (en) * | 2014-04-24 | 2014-08-20 | 中国人民解放军第四军医大学 | Precision mouse spinal cord clamping injury clamp and clamping injury force adjusting method |
| CN104257437A (en) * | 2014-10-20 | 2015-01-07 | 谢杨 | Animal spinal cord injury modeling device |
| CN104257437B (en) * | 2014-10-20 | 2016-01-06 | 谢杨 | A kind of animal spinal cord damage modeling device |
| CN105796204A (en) * | 2016-05-23 | 2016-07-27 | 戴睿武 | Multifunctional experimental animal impacting machine |
| CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
| CN107837124A (en) * | 2017-12-06 | 2018-03-27 | 中南大学湘雅医院 | A kind of animal model with spinal cord damnification beating device and its operating method |
| CN109106464A (en) * | 2018-08-14 | 2019-01-01 | 中国人民解放军第四军医大学 | A kind of device and fixed mechanism being used to prepare spinal cord injury experimental model |
| CN109106464B (en) * | 2018-08-14 | 2023-09-29 | 中国人民解放军第四军医大学 | Device and fixing mechanism for preparing spinal cord injury experimental model |
| CN109009538A (en) * | 2018-08-16 | 2018-12-18 | 新乡医学院第附属医院 | A kind of spinal cord injury simulated experiment percussion device |
| CN109730800A (en) * | 2019-03-15 | 2019-05-10 | 河南医学高等专科学校 | Micro slow positioning injection device is used in a kind of experiment of rat brain |
| CN109730800B (en) * | 2019-03-15 | 2021-02-23 | 河南医学高等专科学校 | Slow injection device that fixes a position of trace for rat brain experiments |
| CN110680542A (en) * | 2019-08-22 | 2020-01-14 | 无锡市中医医院 | Spinal cord injury striking device |
| CN115024851A (en) * | 2022-08-01 | 2022-09-09 | 暨南大学 | Automatic change spinal cord injury animal model preparation facilities |
| CN115024851B (en) * | 2022-08-01 | 2023-10-20 | 暨南大学 | Automatic spinal cord injury animal model preparation device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103006346B (en) | 2015-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103006346A (en) | Spinal cord injury percussion apparatus | |
| CN203595593U (en) | Novel case drop hammer impact testing machine | |
| CN101059413B (en) | Impact absorption tester | |
| CN103263306B (en) | Device for modeling craniocerebral impact injuries of small animals | |
| CN104257437B (en) | A kind of animal spinal cord damage modeling device | |
| CN105723204A (en) | Falling weight deflectometer | |
| CN103971567B (en) | Spinal biomechanicses simulation testing instrument | |
| CN203502315U (en) | Electric power fitting abrasion testing machine | |
| CN211696870U (en) | Impact test stand | |
| CN203354857U (en) | Stretching trainer for training leg flexibility | |
| CN218036190U (en) | Impact testing machine | |
| CN201036686Y (en) | Dual electric motor ball outputting direction control device | |
| CN205262454U (en) | Be used for a dull and stereotyped amount of deflection measuring placer and dull and stereotyped amount of deflection measurement system | |
| CN202351000U (en) | Vehicle transportation platform for collision test of cylinder on side surface of vehicle | |
| CN104634671A (en) | Bilaterally adjustable measuring device for impact testing machine | |
| CN203241306U (en) | Suspended bidirectional adjustable instant force measuring device | |
| CN104361881A (en) | Automatic vibrating playing machine of piano | |
| CN208622262U (en) | A kind of production of modularization elevator sample plate frame and hanging wire instructional device | |
| CN203561563U (en) | Device for testing falling intensity of lead-acid storage battery | |
| CN202366964U (en) | Brake device of steel material dimension control machine | |
| CN103141214A (en) | Calibration test stand for performances of grain loss monitoring sensor of combined harvester | |
| CN103852024A (en) | Visual inspection training platform of gap and jump between machine cover and fender | |
| CN111773028A (en) | Intelligent lower limb active and passive compensation type lateral balance rehabilitation training device | |
| CN208329868U (en) | A kind of architectural engineering fence easy to use | |
| CN110680542A (en) | Spinal cord injury striking device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |