CN107837124A - A kind of animal model with spinal cord damnification beating device and its operating method - Google Patents

A kind of animal model with spinal cord damnification beating device and its operating method Download PDF

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Publication number
CN107837124A
CN107837124A CN201711278541.0A CN201711278541A CN107837124A CN 107837124 A CN107837124 A CN 107837124A CN 201711278541 A CN201711278541 A CN 201711278541A CN 107837124 A CN107837124 A CN 107837124A
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CN
China
Prior art keywords
striking bar
clamping device
striking
displacement sensor
bar clamping
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711278541.0A
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Chinese (zh)
Inventor
胡建中
吕红斌
姜力元
章敏
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Xiangya Hospital of Central South University
Original Assignee
Xiangya Hospital of Central South University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xiangya Hospital of Central South University filed Critical Xiangya Hospital of Central South University
Priority to CN201711278541.0A priority Critical patent/CN107837124A/en
Publication of CN107837124A publication Critical patent/CN107837124A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D1/00Surgical instruments for veterinary use

Abstract

The invention discloses a kind of animal model with spinal cord damnification beating device and its operating method including base, XY slide units, first handle, second handle, striking bar, pilot hole, the first striking bar clamping device, the second striking bar clamping device, magnetostrictive displacement sensor, suspension block, screw mandrel slide unit, connecting rod, arc support and control box.There is arc support on base, screw mandrel slide unit and XY slide units, the first striking bar clamping device is connected by connecting rod on screw mandrel slide unit, arc support vertical direction has magnetostrictive displacement sensor, magnetostrictive displacement sensor bottom position is fixed with the second striking bar clamping device on arc support, experimental subjects fixing device is fixed with XY slide units, first striking bar clamping device, the second striking bar clamping device, screw mandrel slide unit, magnetostrictive displacement sensor are connected by cable connector with control box.The present invention can effectively avoid two-hit, and can measure the landing track of striking bar, and the degree of accuracy is high.

Description

A kind of animal model with spinal cord damnification beating device and its operating method
Technical field
The invention belongs to medicine technology field, is related to a kind of animal model with spinal cord damnification beating device and its operating method, tool Say body, be related to a kind of measurable animal model with spinal cord damnification beating device of strike degree and its operating method.
Background technology
Spinal cord injury (spinal cord injury, SCI) is a kind of serious wound, and its incidence of disease is increasing year by year, The treatment and rehabilitation of spinal cord injury are current medical field a great problems, and reason is that the pathophysiological mechanism after SCI is extremely complex, right Its understanding is also insufficient.In order to preferably study the mechanism of spinal cord injury, pathological change, for effectively treatment provide according to According to establishing a standard, preferable experimental model has great importance.
The standard of clinical similarities, Modulatory character and repeatability frequently as preferable SCI animal models.Have at present a variety of Spinal cord injury model, including spinal cord impact-model, spinal compression model, spinal cord mechanical strain model, ischemia of spinal cord model, spinal cord are horizontal Disconnected model, thecal puncture model, the property absorbed spinal cord injury model.Wherein weight falls impact-model due to the physiology in damage It is acute spinal cord injury the most frequently used at present closer to the spinal cord injury of people in terms of the Pathological Physiology of reaction and secondary injury One of animal model.
At present, the beating device of domestic design has that hitting dynamics theoretical value is difficult to verify, Impulse time can not be determined accurately The deficiencies of.Therefore, a kind of measurable animal model with spinal cord damnification beating device of strike degree is badly in need of in this area.
The content of the invention
The purpose of the present invention is to overcome deficiency of the prior art, there is provided a kind of animal model with spinal cord damnification beating device and its Operating method, the measurable animal model with spinal cord damnification beating device strong operability of the strike degree, can not only effectively be avoided secondary Strike, and the landing track of striking bar can be measured, obtain strike degree of the striking bar to spinal cord.
Its technical scheme is as follows:
A kind of animal model with spinal cord damnification beating device, including base 19, XY slide units 2, first handle 1, second handle 3, beat Hit rod 5, pilot hole 13, the first striking bar clamping device 7, the second striking bar clamping device 16, magnetostrictive displacement sensor 10, Suspension block 8, screw mandrel slide unit 12, connecting rod 15, arc support 11 and control box 18;
The base 19 is provided with arc support 11, screw mandrel slide unit 12 and XY slide units 2;
The screw mandrel slide unit 12 is connected by the striking bar clamping device 7 of connecting rod 15 and first, and can be in vertical side To moving up and down, the first striking bar clamping device 7 is used to clamp striking bar 5 to level altitude and discharge, the striking bar 5 Top be fixed with the suspension block 8 of the magnetostrictive displacement sensor 10;
The vertical direction of arc support 11 is provided with magnetostrictive displacement sensor 10, the magnetostrictive displacement sensor Second striking bar clamping device 16 is fixed on the arc support 11 by 10 bottom position, the second striking bar clamping dress Put 16 and once hit for striking bar 5 and terminate to clamp striking bar 5 afterwards;
Experimental subjects fixing device 4 is fixed with the XY slide units 2, the experimental subjects fixing device 4 passes through described One handle 1, the adjusting position of second handle 3;
The first striking bar clamping device 7, the second striking bar clamping device 16, screw mandrel slide unit 12, magnetostrictive displacement Sensor 10 is connected by cable connector with control box 18.
Further, the first striking bar clamping device includes the first steering wheel 6 and the first fixture 9.
Further, the second striking bar clamping device includes the second steering wheel 17 and the second fixture 14.
Further, the striking bar 5 passes through the free-falling of pilot hole 13.
The operating method of animal model with spinal cord damnification beating device of the present invention, comprises the following steps:
Step 1. switches on power, and now power supply indicator is bright, and system enters init state;
Step 2. takes out striking bar, passes through pilot hole below striking bar, passes through button control the first striking bar clamping device Clamp striking bar top;
Experimental subjects is fixed on XY slide units by step 3. with experimental subjects fixing device, adjusts the first-hand of XY slide units Handle, second handle, the hit position of experimental subjects is set to be in the underface of striking bar;
Step 4. control box controls screw mandrel slide unit, drives striking bar to rise to setting height;
Step 5. control box controls the first striking bar clamping device release striking bar, striking bar free-falling, controls simultaneously The displacement information that box collection magnetostrictive displacement sensor is obtained by the suspension block being fixed in striking bar, obtains striking bar Real time position;
Step 6. control box is after striking bar whereabouts, the strike of control the second striking bar gripping means grips bounce-back Rod.
Step 7. removes experimental subjects, takes out striking bar, deenergization, arranges cleaning equipment, complete experiment.
Beneficial effects of the present invention:
A kind of measurable animal model with spinal cord damnification beating device of strike degree of the present invention, realized and beaten by screw mandrel slide unit The regulation of the i.e. hitting dynamics of height is hit, measures the fall trajectory of striking bar in real time by magnetostrictive displacement sensor, and according to The situation of fall trajectory, striking bar gripping means grips striking bar is controlled before second strike by control box, is being kept away While exempting from two-hit, strike degree can also be drawn according to striking bar fall trajectory.Due to being hit using gravity type, therefore It is versatile easy to spread;Automatic mode of operation, the random error that operating personnel bring is avoided, test repeatability is good, accurate Exactness is high.
Brief description of the drawings
Fig. 1 is the structural representation of animal model with spinal cord damnification beating device of the present invention.
Embodiment
Technical scheme is described in more detail with reference to the accompanying drawings and detailed description.
Reference picture 1, a kind of animal model with spinal cord damnification beating device, including base 19, XY slide units 2, first handle 1, second Handle 3, striking bar 5, pilot hole 13, the first striking bar clamping device 7, the second striking bar clamping device 16, magnetostrictive displacement Sensor 10, suspension block 8, screw mandrel slide unit 12, connecting rod 15, arc support 11 and control box 18;
The base 19 is provided with arc support 11, screw mandrel slide unit 12 and XY slide units 2;
The screw mandrel slide unit 12 is connected by the striking bar clamping device 7 of connecting rod 15 and first, and can be in vertical side To moving up and down, the first striking bar clamping device 7 is used to clamp striking bar 5 to level altitude and discharge, the striking bar 5 Top be fixed with the suspension block 8 of the magnetostrictive displacement sensor 10;
The vertical direction of arc support 11 is provided with magnetostrictive displacement sensor 10, the magnetostrictive displacement sensor Second striking bar clamping device 16 is fixed on the arc support 11 by 10 bottom position, the second striking bar clamping dress Put 16 and once hit for striking bar 5 and terminate to clamp striking bar 5 afterwards;
Experimental subjects fixing device 4 is fixed with the XY slide units 2, the experimental subjects fixing device 4 passes through described One handle 1, the adjusting position of second handle 3;
The first striking bar clamping device 7, the second striking bar clamping device 16, screw mandrel slide unit 12, magnetostrictive displacement Sensor 10 is connected by cable connector with control box 18.
The first striking bar clamping device includes the first steering wheel 6 and the first fixture 9.
The second striking bar clamping device includes the second steering wheel 17 and the second fixture 14.
The striking bar 5 passes through the free-falling of pilot hole 13.
The experimental subjects fixing device 4 of the present invention is fixed on XY slide units 2, can be by rotating first handle 1, second-hand Handle 3 adjusts front and rear, the position of left and right.
The suspension block 8 of magneto strictive sensor 10 is fixed with the striking bar 5 of the present invention, the position of suspension block 8 is exactly to beat The position of rod 5 is hit, the track that suspension block 8 moves is exactly the track that striking bar 5 moves.
The screw mandrel slide unit 12 of the present invention connects the first striking bar clamping device 7, and the first striking bar clamping device 7, which clamps, to be beaten The top of rod 5 is hit, moving up and down for screw mandrel slide unit 12 can drive the upper-lower position of striking bar 5 to move.
The present invention devises computer terminal host computer, and the host computer mainly completes Information Collecting & Processing and control, is used for Strike height is set;Control the first striking bar clamping device 7, clamping striking bar 5 and release striking bar 5;Gather magnetostriction position The data of displacement sensor 10, show the strike track of striking bar 5;Automatically determine the second striking bar clamping device 16 clamping striking bar 5 time;According to strike degree of the strike trajectory calculation striking bar 5 of striking bar 5 to experimental subjects.
The animal model with spinal cord damnification beating device of the present invention in a particular application, comprises the following steps:Step 1. connects electricity Source, now power supply indicator is bright, and system enters init state;
Step 2. takes out striking bar, passes through pilot hole below striking bar, passes through button control the first striking bar clamping device Clamp striking bar top;
Experimental subjects is fixed on XY slide units by step 3. with experimental subjects fixing device, adjusts the first-hand of XY slide units Handle, second handle, the hit position of experimental subjects is set to be in the underface of striking bar;
Step 4. control box controls screw mandrel slide unit, drives striking bar to rise to setting height;
Step 5. control box controls the first striking bar clamping device release striking bar, striking bar free-falling, controls simultaneously The displacement information that box collection magnetostrictive displacement sensor is obtained by the suspension block being fixed in striking bar, obtains striking bar Real time position;
Step 6. control box is after striking bar whereabouts, the strike of control the second striking bar gripping means grips bounce-back Rod.
Step 7. removes experimental subjects, takes out striking bar, deenergization, arranges cleaning equipment, complete experiment.
The foregoing is only a preferred embodiment of the present invention, protection scope of the present invention not limited to this, any ripe Those skilled in the art are known in the technical scope of present disclosure, the letter for the technical scheme that can be become apparent to Altered or equivalence replacement are each fallen within protection scope of the present invention.

Claims (5)

  1. A kind of 1. animal model with spinal cord damnification beating device, it is characterised in that:Including base (19), XY slide units (2), first handle (1), second handle (3), striking bar (5), pilot hole (13), the first striking bar clamping device (7), the second striking bar clamping device (16), magnetostrictive displacement sensor (10), suspension block (8), screw mandrel slide unit (12), connecting rod (15), arc support (11) and Control box (18);
    The base (19) is provided with arc support (11), screw mandrel slide unit (12) and XY slide units (2);
    The screw mandrel slide unit (12) is connected by the connecting rod (15) and the first striking bar clamping device (7), and can be vertical Direction moves up and down, and the first striking bar clamping device (7) is used to clamp striking bar (5) to level altitude and discharge, described The suspension block (8) of the magnetostrictive displacement sensor (10) is fixed with the top of striking bar (5);
    Arc support (11) vertical direction is provided with magnetostrictive displacement sensor (10), the magnetostrictive displacement sensor (10) the second striking bar clamping device (16) is fixed on the arc support (11) by bottom position, second striking bar Clamping device (16) is once hit for striking bar (5) to be terminated to clamp striking bar (5) afterwards;
    Experimental subjects fixing device (4) is fixed with the XY slide units (2), the experimental subjects fixing device (4) is by described First handle (1), second handle (3) adjusting position;
    The first striking bar clamping device (7), the second striking bar clamping device (16), screw mandrel slide unit (12), magnetostriction position Displacement sensor (10) is connected by cable connector with control box (18).
  2. 2. animal model with spinal cord damnification beating device according to claim 1, it is characterised in that:The first striking bar clamping Device includes the first steering wheel (6) and the first fixture (9).
  3. 3. animal model with spinal cord damnification beating device according to claim 1, it is characterised in that:The second striking bar clamping Device includes the second steering wheel (17) and the second fixture (14).
  4. 4. animal model with spinal cord damnification beating device according to claim 1, it is characterised in that:The striking bar (5) passes through Pilot hole (13) free-falling.
  5. 5. the operating method of animal model with spinal cord damnification beating device described in claim 1, it is characterised in that:Comprise the following steps:
    Step 1. switches on power, and now power supply indicator is bright, and system enters init state;
    Step 2. takes out striking bar, passes through pilot hole below striking bar, passes through button control the first striking bar gripping apparatus grips Firmly striking bar top;
    Experimental subjects is fixed on XY slide units by step 3. with experimental subjects fixing device, adjusts the first handle of XY slide units, the Two handles, the hit position of experimental subjects is set to be in the underface of striking bar;
    Step 4. control box controls screw mandrel slide unit, drives striking bar to rise to setting height;
    Step 5. control box controls the first striking bar clamping device release striking bar, striking bar free-falling, while control box is adopted The displacement information that collection magnetostrictive displacement sensor is obtained by the suspension block being fixed in striking bar, obtains the real-time of striking bar Position;
    Step 6. control box is after striking bar whereabouts, the striking bar of control the second striking bar gripping means grips bounce-back;
    Step 7. removes experimental subjects, takes out striking bar, deenergization, arranges cleaning equipment, complete experiment.
CN201711278541.0A 2017-12-06 2017-12-06 A kind of animal model with spinal cord damnification beating device and its operating method Pending CN107837124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711278541.0A CN107837124A (en) 2017-12-06 2017-12-06 A kind of animal model with spinal cord damnification beating device and its operating method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711278541.0A CN107837124A (en) 2017-12-06 2017-12-06 A kind of animal model with spinal cord damnification beating device and its operating method

Publications (1)

Publication Number Publication Date
CN107837124A true CN107837124A (en) 2018-03-27

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109717982A (en) * 2019-03-15 2019-05-07 河南医学高等专科学校 A kind of percussion device causing the damage of minitype animal experiment brainpan
CN110169839A (en) * 2019-05-29 2019-08-27 上海塔望智能科技有限公司 A kind of animal spinal cord injury test macro

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406409A (en) * 2008-11-05 2009-04-15 成都医学院 Digital type instrument for manufacturing animal model with spinal cord damnification
CN101779987A (en) * 2010-03-16 2010-07-21 胡建中 Acute spinal cord injury animal model modeling impactor
CN102379752A (en) * 2011-08-22 2012-03-21 中南大学湘雅医院 Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model
CN103006346A (en) * 2012-12-31 2013-04-03 中国科学院自动化研究所 Spinal cord injury percussion apparatus
CN104764393A (en) * 2015-03-27 2015-07-08 扬州工业职业技术学院 High-precision magnetostrictive displacement sensor
CN208481515U (en) * 2017-12-06 2019-02-12 中南大学湘雅医院 A kind of animal model with spinal cord damnification beating device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101406409A (en) * 2008-11-05 2009-04-15 成都医学院 Digital type instrument for manufacturing animal model with spinal cord damnification
CN101779987A (en) * 2010-03-16 2010-07-21 胡建中 Acute spinal cord injury animal model modeling impactor
CN102379752A (en) * 2011-08-22 2012-03-21 中南大学湘雅医院 Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model
CN103006346A (en) * 2012-12-31 2013-04-03 中国科学院自动化研究所 Spinal cord injury percussion apparatus
CN104764393A (en) * 2015-03-27 2015-07-08 扬州工业职业技术学院 High-precision magnetostrictive displacement sensor
CN208481515U (en) * 2017-12-06 2019-02-12 中南大学湘雅医院 A kind of animal model with spinal cord damnification beating device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109717982A (en) * 2019-03-15 2019-05-07 河南医学高等专科学校 A kind of percussion device causing the damage of minitype animal experiment brainpan
CN109717982B (en) * 2019-03-15 2020-07-24 河南医学高等专科学校 Striking device for causing brain injury of small experimental animal
CN110169839A (en) * 2019-05-29 2019-08-27 上海塔望智能科技有限公司 A kind of animal spinal cord injury test macro

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