CN103005445A - Compound healthcare product capable of improving immunity - Google Patents
Compound healthcare product capable of improving immunity Download PDFInfo
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- CN103005445A CN103005445A CN2012105932501A CN201210593250A CN103005445A CN 103005445 A CN103005445 A CN 103005445A CN 2012105932501 A CN2012105932501 A CN 2012105932501A CN 201210593250 A CN201210593250 A CN 201210593250A CN 103005445 A CN103005445 A CN 103005445A
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- radix astragali
- american ginseng
- matrimony vine
- health products
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Abstract
The invention relates to a compound healthcare product with a function of improving human immunity, and specifically relates to a preparation process and an application of the healthcare product. The prescription combination is carried out under the guidance of a combination rule of the traditional Chinese medicine according to the theory of the traditional Chinese medicine, and the specific prescription is as follows: 5-15 parts of cordyceps militaris, 8-20 parts of American ginseng, 15-40 parts of radix astragali and 10-25 parts of medlar. The American ginseng, the radix astragali and the medlar are extracted by using a reflux method, extract liquid is subjected to ultrasonic treatment and centrifugation, and then upper supernatant is adopted and concentrated to turn to from an extractum. The extractum is fully and uniformly mixed with the cordyceps militaris obtained by using a superfine pulverizing method and appropriate auxiliary materials to prepare granules, tablets or capsules and the like finally. All the materials adopted during the preparation of the product are medical and edible traditional Chinese medicines which are safe and nontoxic, so the compound healthcare product is suitable for long-term use and effectively make up the function limitation of a single-component cordyceps militaris healthcare product.
Description
Technical field
The invention provides a kind of complex health care product that strengthens the body immunity function that has, be specifically related to preparation technology and the purposes of these health products, belong to the medical health product technical field.
Background technology
Immune system is the defense mechanism of human body self, be human body identification and any foreign matter (virus, bacterium etc.) of eliminating external intrusion, process the ability of self cell and identification and processing vivo mutations cell and the virus infected cell of old and feeble, damage, death, sex change.Therefore improve immunity of organisms for the very important effect that is formed with that prevents and control disease, inhibition tumour.Modern medicine thinks that strengthening immunity is to change sub-health state into health status.According to World Health Organization's investigation, in worldwide, there is the crowd more than 70% to be in sub-health state.Obviously, medicine can not solve all problems, and the nutritional intervention method has become the method for an extensive use of Promote immunity systemic-function at present, and the Chinese medicine of integration of drinking and medicinal herbs class then provides the good material that replenishes and strengthen immunity of organisms for the mankind.In recent years, the mechanism of herbal polysaccharide immunoregulation effect and structure activity study have been obtained outstanding achievement, so that polysaccharide becomes the focus of immunopharmacology research.Therefore, application study and the product development of reinforcement herbal polysaccharide are imperative.
Polysaccharide is one of large biological molecule of needed by human, and the decocting method of average family can only make in the medicinal material about 1% polysaccharide molten in soup, if directly edible human body intestinal canal also is limited to the absorption of macromolecular polysaccharide wherein.So; Only have by specific extraction process, obtain in a large number the polysaccharide component in the Chinese medicine, and make the oral formulations that is easily absorbed by the body, human body can add to required polysaccharide component quickly and easily, reaches the purpose that improves function of immune system.
According to the literature, northern Chinese caterpillar Fungus, American Ginseng, the Radix Astragali and matrimony vine all contain abundant polysaccharide component, have the effect that strengthens immunity of organisms.The present invention carries out prescription according to traditional Chinese medical theory with this four flavors Chinese medicine, can strengthen original drug effect of each composition, and each composition is complemented each other, and body immunity is had significant raising effect.The raw materials used medicine of these health products is the Chinese medicine of " integration of drinking and medicinal herbs ", safety non-toxic, long-term taking can improve human body sub-health status, improve people's quality of life, has effectively remedied the effect limitation of northern Chinese caterpillar Fungus one-component health products, has potential Social benefit and economic benefit.
Summary of the invention
The invention provides a kind of compound health-care food with enhancing body immunity function and preparation method thereof.These health products can strengthen immunity, the nourishing health of human body, have simultaneously liver-kidney tonifying, nourishing yin and nourishing blood, hemostasis and phlegm concurrently, and the effect of powerful antibody generation, complement activation is detoxified, added in heat-clearing invigorating the spleen, clearing damp.
The traditional Chinese medical science is thought, American Ginseng: cold in nature, and sweet and slightly bitter taste, cool in nature, the thoughts of returning home, lung, kidney channel, the function that have boosting qi and nourishing yin, the clear fire of deficiency type, promotes the production of body fluid to quench thirst is monarch drug in a prescription.The Radix Astragali: it is sweet to distinguish the flavor of, and tonifying middle-Jiao and Qi warm in nature is ministerial drug, share the merit that can strengthen its tonifying middle-Jiao and Qi with American Ginseng.Though American Ginseng and Radix Astragali nature and flavor are anti-, function is similar, and mutual reinforcement between is for using.In addition, also there is bibliographical information fever and chills medicine compatibility to complement each other.Northern Chinese caterpillar Fungus: property is flat, and it is sweet to distinguish the flavor of, and has kidney-tonifying health-care, immunological regulation, prevents liver fibrosis, the effect of hemostasis and phlegm, expansion tracheae, calmness, cancer-resisting.Matrimony vine: it is sweet to distinguish the flavor of, and property is flat returns liver, kidney, lung channel, have filling liver kidney benefit vital essence, make eye bright calm the nerves, the effect of hard muscles and bones, the diseases such as, soreness and weakness of waist and knees sallow to liver-kidney Yin deficiency, the deficiency of blood have significant curative effect.Matrimony vine is similar with northern Chinese caterpillar Fungus, the mutual reinforcement between mutual-assistance.The present invention makes up four traditional Chinese medicine by a certain percentage, meets the combination principle of Chinese medicine, can make the drug effect of each composition produce good synergy.
Preparation method of the present invention is as follows:
Prescription forms:
Northern Chinese caterpillar Fungus 5-15 part, American Ginseng 8-20 part, Radix Astragali 15-40 part, matrimony vine 10-25 part.
Concrete steps are:
(1) utilize micronizer that northern Chinese caterpillar Fungus is pulverized, cross the 60-100 mesh sieve, for subsequent use.Matrimony vine, the Radix Astragali and American Ginseng are placed in the container, use distilled water immersion 1 hour, for subsequent use.
(2) extract concentrated: use matrimony vine, the Radix Astragali and American Ginseng after circumfluence method will be soaked under 90 ℃, to extract, by Orthogonal Experiment and Design the consumption of distilled water (for 8-12 times of extracting the raw medicinal material gross weight), extraction time (1-3 hour) and extraction time (1-3 time) be optimized.With extracting liquid filtering, merging filtrate is got the upper strata settled solution after ultrasonic, centrifugal, and clarified solution is concentrated into the medicinal extract that relative density is 1.20-2.10 (70 ℃), collects medicinal extract, and is for subsequent use.
(3) with northern Chinese caterpillar Fungus fine powder, different types of vitamin and amino acid, and suitable pharmaceutic adjuvant (such as filler, disintegrant etc.) is added to softwood processed in the medicinal extract, (12-24 order) granulation of sieving, drying, sieve (12-24 order) whole grain.
(4) the direct packing of granule that step (3) is made namely gets the granule of these health products.
(5) carry out compressing tablet after adding the auxiliary materials such as suitable lubricant, outer disintegrant in the particle that makes to step (3), compacting obtains can carrying out dressing behind the plain sheet and prepares sugar coated tablet or Film coated tablets.
(6) add the auxiliary materials such as suitable glidant, lubricant in the particle that makes to step (3), pour into capsule material and polishing, be these health products hard capsule.
The specific embodiment
Embodiment 1
(1) with the northern Chinese caterpillar Fungus ultramicro grinding, cross 100 mesh sieves, it is for subsequent use to get 5g medicinal powder.Matrimony vine 15g, Radix Astragali 20g, American Ginseng 10g are placed clean container, use distilled water immersion 1 hour, for subsequent use.
(2) extraction is concentrated: use matrimony vine, the Radix Astragali and American Ginseng after circumfluence method will be soaked to extract under 90 ℃ temperature, the consumption of distilled water is 8 times of extraction raw medicinal material gross weight, and extraction time is 2 hours, extraction time 2 times; Filter, merging filtrate, filtrate is concentrated into the medicinal extract that relative density is 1.70 (70 ℃), collects medicinal extract, and is for subsequent use.
(3) northern Chinese caterpillar Fungus fine powder, an amount of VE, folic acid, Taurine, starch, dextrin are added to softwood processed in the medicinal extract, cross 18 mesh sieves and granulate, 60 ℃ of dryings 1 hour are crossed the whole grain of 16 mesh sieves.
(4) above-mentioned particle is packed in the bag and sealing is the granule of these health products.
Embodiment 2
(1) with the northern Chinese caterpillar Fungus ultramicro grinding, cross 100 mesh sieves, it is for subsequent use to get 3g medicinal powder.Matrimony vine 10g, Radix Astragali 15g, American Ginseng 10g are placed clean container, use distilled water immersion 1 hour, for subsequent use.
(2) extraction is concentrated: use matrimony vine, the Radix Astragali, American Ginseng after circumfluence method will be soaked to extract under 90 ℃ temperature, the consumption of distilled water is 10 times of extraction raw medicinal material gross weight, and extraction time is 2 hours, extraction time 3 times; Filter, merging filtrate, filtrate is concentrated into the medicinal extract that relative density is 2.10 (70 ℃), collects medicinal extract, and is for subsequent use.
(3) with the northern Chinese caterpillar Fungus fine powder,, an amount of VE, folic acid, Taurine, starch, sucrose add softwood processed in the medicinal extract, crosses 18 mesh sieves and granulate, 60 ℃ of dryings 1 hour are crossed the whole grain of 16 mesh sieves.
(4) add an amount of dolomol, talcum powder, microcrystalline cellulose in the particle of step 3 gained, compacting gets final product in flakes.
Embodiment 3
(1) with the northern Chinese caterpillar Fungus ultramicro grinding, cross 80 mesh sieves, it is for subsequent use to get 6g medicinal powder.Matrimony vine 15g, Radix Astragali 25g, American Ginseng 15g are placed clean container, use distilled water immersion 1 hour, for subsequent use.
(2) extraction is concentrated: use matrimony vine, the Radix Astragali and American Ginseng after circumfluence method will be soaked to extract under 90 ℃ temperature, the consumption of distilled water is 10 times of extraction raw medicinal material gross weight, and extraction time is 2 hours, extraction time 3 times; Filter, merging filtrate, filtrate is concentrated into the medicinal extract that relative density is 1.70 (70 ℃), collects medicinal extract, and is for subsequent use.
(3) northern Chinese caterpillar Fungus fine powder, an amount of VE, folic acid, Taurine, starch are added softwood processed in the medicinal extract, cross 24 mesh sieves and granulate, 60 ℃ of dryings 1 hour are crossed the whole grain of 24 mesh sieves.
(4) add an amount of talcum powder in the particle of step 3 gained, by the capsule filling machine can, the capsule of filling with good polishes in sanding machine, rejects damaged capsule, and packing namely gets the hard capsule of these health products.
The above only is preferred embodiment of the present invention, is not that the present invention is done any restriction, every according to the invention technical spirit to any simple modification and change that above embodiment does, all belong in the protection domain of technical solution of the present invention.
Claims (7)
1. the invention provides a kind of complex health care product that improves the body immunity function that has, it is characterized in that mainly being made by ratio of weight and the number of copies by following Chinese medicine: northern Chinese caterpillar Fungus 5-15 part, American Ginseng 8-20 part, Radix Astragali 15-40 part, matrimony vine 10-25 part.
2. described according to claim 1, these health products are characterised in that the composition and ratio of preferred Chinese medicine is: northern Chinese caterpillar Fungus 7-12 part, American Ginseng 10-15 part, Radix Astragali 25-30 part, matrimony vine 15-20 part.
3. described with claim 2 according to claim 1, this formulation with the health products that strengthen the body immunity function can be granule, tablet or capsule etc.
4. described with claim 3 according to claim 1, concrete preparation method's step of these health products is as follows:
(1) utilize micronizer that northern Chinese caterpillar Fungus is pulverized, cross the 60-100 mesh sieve, for subsequent use.Matrimony vine, the Radix Astragali and American Ginseng are placed in the container, use distilled water immersion 1 hour, for subsequent use.
(2) extract concentrated: use matrimony vine, the Radix Astragali and American Ginseng after circumfluence method will be soaked under 90 ℃, to extract, by Orthogonal Experiment and Design the consumption of distilled water (for 8-12 times of extracting the raw medicinal material gross weight), extraction time (1-3 hour) and extraction time (1-3 time) be optimized.With extracting liquid filtering, merging filtrate is got the upper strata settled solution after ultrasonic, centrifugal, and clarified solution is concentrated into the medicinal extract that relative density is 1.20-2.10 (70 ℃), collects medicinal extract, and is for subsequent use.
(3) northern Chinese caterpillar Fungus fine powder and suitable auxiliary material (such as filler, disintegrant etc.) are added to softwood processed in the medicinal extract, sieve (12-24 order) granulates, drying, and sieve (12-24 order) whole grain namely gets granule.Add in the particle and can be pressed into tablet behind the auxiliary material such as lubricant or can prepares capsule etc.
5. described according to claim 4, can add a small amount of different types of vitamin and amino acid in these health products as complementary nutritional labeling.
6. described according to claim 4, the auxiliary material that relates among the present invention can be the pharmaceutic adjuvant of the required all kinds of preparation granule, Tablet and Capsula agent.
7. described with claim 4 according to claim 3, the tablet of these health products can be plain sheet, sugar coated tablet or Film coated tablets.
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Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103211220A (en) * | 2013-04-25 | 2013-07-24 | 福建永生活力生物工程有限公司 | Health food with function of enhancing immunity and preparation method thereof |
CN103494197A (en) * | 2013-10-09 | 2014-01-08 | 吉林省现代中药工程研究中心有限公司 | Health-care food with functions of enhancing immunity and assisting to reduce blood sugar and preparation method of food |
CN104886703A (en) * | 2015-05-07 | 2015-09-09 | 马超锋 | Plant beverage containing artificially cultivated cordyceps sinensis, astragalus membranaceus and fruits of Chinese wolfberries and formula and manufacturing method |
CN106509780A (en) * | 2015-09-15 | 2017-03-22 | 哈尔滨灵椿味道食品开发有限公司 | Chinese magnoliavine fruit soup blend for invigorating spleen-stomach and replenishing qi and preparation method of Chinese magnoliavine fruit soup blend |
CN106857928A (en) * | 2017-01-09 | 2017-06-20 | 烟台新时代健康产业有限公司 | A kind of health protection tea of clearing heat and promoting diuresis and preparation method thereof |
CN108837037A (en) * | 2018-04-18 | 2018-11-20 | 北华大学 | A kind of composition and preparation method thereof with strengthen immunity function |
CN109105734A (en) * | 2018-08-17 | 2019-01-01 | 葛强 | A kind of novel herbal paste production method |
CN109200215A (en) * | 2018-10-25 | 2019-01-15 | 湖南博隽生物医药有限公司 | A kind of peritoneal dialysis solution and preparation method thereof |
CN109259226A (en) * | 2018-10-23 | 2019-01-25 | 宕昌县福江源药业科技有限责任公司 | A kind of health care product prescription added with Radix Astragali |
CN111357908A (en) * | 2020-03-11 | 2020-07-03 | 山西大学 | Preparation method of astragalus membranaceus composite solid beverage capable of improving immunity |
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CN1133733A (en) * | 1995-04-19 | 1996-10-23 | 马胜山 | Process for preparing cordyceps American ginseng |
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CN1133733A (en) * | 1995-04-19 | 1996-10-23 | 马胜山 | Process for preparing cordyceps American ginseng |
KR20080056651A (en) * | 2006-12-18 | 2008-06-23 | 박용진 | A composition comprising the processed extract of panax quinquefolium l. for the prevention and treatment of cancer |
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Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103211220A (en) * | 2013-04-25 | 2013-07-24 | 福建永生活力生物工程有限公司 | Health food with function of enhancing immunity and preparation method thereof |
CN103494197A (en) * | 2013-10-09 | 2014-01-08 | 吉林省现代中药工程研究中心有限公司 | Health-care food with functions of enhancing immunity and assisting to reduce blood sugar and preparation method of food |
CN104886703A (en) * | 2015-05-07 | 2015-09-09 | 马超锋 | Plant beverage containing artificially cultivated cordyceps sinensis, astragalus membranaceus and fruits of Chinese wolfberries and formula and manufacturing method |
CN106509780A (en) * | 2015-09-15 | 2017-03-22 | 哈尔滨灵椿味道食品开发有限公司 | Chinese magnoliavine fruit soup blend for invigorating spleen-stomach and replenishing qi and preparation method of Chinese magnoliavine fruit soup blend |
CN106857928A (en) * | 2017-01-09 | 2017-06-20 | 烟台新时代健康产业有限公司 | A kind of health protection tea of clearing heat and promoting diuresis and preparation method thereof |
CN108837037A (en) * | 2018-04-18 | 2018-11-20 | 北华大学 | A kind of composition and preparation method thereof with strengthen immunity function |
CN109105734A (en) * | 2018-08-17 | 2019-01-01 | 葛强 | A kind of novel herbal paste production method |
CN109259226A (en) * | 2018-10-23 | 2019-01-25 | 宕昌县福江源药业科技有限责任公司 | A kind of health care product prescription added with Radix Astragali |
CN109200215A (en) * | 2018-10-25 | 2019-01-15 | 湖南博隽生物医药有限公司 | A kind of peritoneal dialysis solution and preparation method thereof |
CN111357908A (en) * | 2020-03-11 | 2020-07-03 | 山西大学 | Preparation method of astragalus membranaceus composite solid beverage capable of improving immunity |
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Application publication date: 20130403 |