CN106333987A - Health care product for enhancing immunity and preparation method thereof - Google Patents

Health care product for enhancing immunity and preparation method thereof Download PDF

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Publication number
CN106333987A
CN106333987A CN201610963279.2A CN201610963279A CN106333987A CN 106333987 A CN106333987 A CN 106333987A CN 201610963279 A CN201610963279 A CN 201610963279A CN 106333987 A CN106333987 A CN 106333987A
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China
Prior art keywords
american ginseng
health products
powder
barrenwort
capsule
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CN201610963279.2A
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Chinese (zh)
Inventor
许震
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WUHU NOKAN BIOTECHNOLOGY CO Ltd
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WUHU NOKAN BIOTECHNOLOGY CO Ltd
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Priority to CN201610963279.2A priority Critical patent/CN106333987A/en
Publication of CN106333987A publication Critical patent/CN106333987A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/424Gynostemma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a health care product for enhancing immunity and a preparation method thereof and relates to the field of health care products. On a basis of 1000 particles of the health care product for enhancing immunity, the health care product comprises 150-250 g of paecilomyces hepialid powder and 150-250 g of dry paste powder of American ginseng, epimedium herb and gynostemma pentaphyllum after extraction, filtration and concentration. The dosages of American ginseng, epimedium herb and gynostemma pentaphyllum are 200-300 g of American ginseng, 500-600 g of epimedium herb and 550-650 g of gynostemma pentaphyllum. The composition can be made into tablets, granules, hard capsules or soft capsules. The health care product aims to improve human body immunity and blood circulation and has effects of supplementing vigor and relieving fatigue.

Description

A kind of health products of strengthen immunity and preparation method thereof
Technical field
The present invention relates to health products direction is and in particular to a kind of health products of strengthen immunity and preparation method thereof.
Background technology
Resistance refers under the control of central nervous system, and each system of human body is shared out the work and help one another, close fit, protects Demonstrate,prove being normally carried out of vital movement.Wherein function of immune system is the intrusion of the extraneous pathogenic microorganism of defence, it is to avoid cause each Plant disease.This defence capability of human body is exactly resistance.Because current Western medicine cannot fast and effectively be built up resistance, therefore There is great demand to the Chinese medicine quickly effectively built up resistance in people.
Content of the invention
According to above the deficiencies in the prior art, the technical problem to be solved is to propose a kind of strengthen immunity Health products and preparation method thereof, it is therefore an objective to improve body immunity, improve blood circulation, and have supplementary energy and alleviate tired The effect of labor.
The technical solution used in the present invention is: a kind of health products of strengthen immunity, with 1000 described strengthen immunities Health products meter, comprise following material and its content: peacilomyce hepiahi bacterium powder 150-250g, American Ginseng, barrenwort and strand Blue extract, filtration, concentrate after dried cream powder 150-250g.
A kind of health products of strengthen immunity, in terms of the health products of 1000 described strengthen immunities, comprise following material And its content: peacilomyce hepiahi bacterium powder 200g, American Ginseng, barrenwort and gynostemma pentaphylla extract, filtration, concentrate after dried cream powder 200g.
In above-mentioned composition, the consumption proportion of described American Ginseng, barrenwort and gynostemma pentaphylla: American Ginseng 200-300g, excessive sheep Leaves of pulse plants 500-600g, gynostemma pentaphylla 550-650g.Described composition can be made into tablet, granule, hard capsule or soft capsule.
Peacilomyce hepiahi bacterium powder is upgrading substitute in pharmacy industry for the natural cordyceps, low price, applicable people Group extensively, has invigorating kidney yang, moistening lung, improves the health care of sleep quality, stress of releiving, and supplements energy, the effect of fatigue-relieving;Acceptable Nourishing qi and blood, anti-aging is simultaneously built up resistance, and improves physique;Build up resistance, antiallergy, mitigating brain fatigue, lifting memory Power.
American Ginseng, sweet pungent, cool in nature, nontoxic." special product research " thinks American Ginseng enter the heart, lung, kidney three warp, with help is Main, can nourishing Yin and falling fire, nourishing generate fluid;Main component is ginsenoside, effectively strengthens central functions, in antitumor, antioxygen Change, hypoglycemic is hypotensive etc., and that aspect has functions that is good.
Barrenwort, its temperature and nontoxic." Bencao Jingshu " thinks Yan Hanzhe, by mistake.Pungent to moisten kidney, sweet temperature Yiyang gas, therefore Main impotence is positive absolutely, beneficial gas power, Qiang Zhi.Pains in the penis person, liver kidney deficiency, help two warp, bitterly from only.
Gynostemma pentaphylla, cold in nature, sweet, slight bitter, return lung, spleen, the heart, kidney channel, have heat-clearing quench one's thirst, clearing lung and eliminating phlegm cough-relieving, tonifying Qi Nourishing Yin and promoting production of body fluid, the effect of mental-tranquilization controlling nocturnal emission with astringent drugs.
A kind of preparation method of the health products of strengthen immunity, methods described step includes: step one, American Ginseng, excessive sheep The leaves of pulse plants and gynostemma pentaphylla are cleaned, select, and make net medicinal material, plus 10 times amount 75% alcohol reflux extracts 2 times, 2 hours every time, filters, closes And filtrate;Step 2, to the filtrate recycling ethanol in step one, be concentrated into the clear cream that relative density is 1.30-1.35;Step 3rd, the clear cream in step 2 is dried under 70 DEG C of vacuum environments, pulverizes, sieves, prepared dried cream powder;Step 4, bat moth Paecilomyces varioti bacterium powder is crossed 80 mesh sieves and peacilomyce hepiahi bacterium fine powder is obtained;Step 5, by peacilomyce hepiahi bacterium fine powder and step 3 In dried cream powder mix 30 minutes, with 80% ethanol softwood, granulation of sieving, whole grain of sieving after drying, prepared semi-finished granules; Step 6, semi-finished granules are sent in capsule filling machine, and capsule is filled, prepared capsule.
The medicine have the advantages that the health products of strengthen immunity that the present invention provides, selected medicine is neither similar medicine Arranged side by side, be not the addition of identical drug effect, but for fatigue formed the Etiological interpretation of the cause, onset and process of an illness carry out drugs to form a prescription.Adopt in side With yin yang complementarity, the balance principle organic assembling of the cool mutual Ji of temperature, specially make according to Chinese's physique, can strengthen immunity, delay Solution fatigue.
Specific embodiment
Below by the description to embodiment, for example involved shape of each component of the specific embodiment of the present invention, structure Make, the mutual alignment between each several part and annexation, the effect of each several part and operation principle, manufacturing process and the side of operating with Method etc., is described in further detail, completeer to help those skilled in the art that the inventive concept of the present invention, technical scheme are had Whole, accurate and deep understanding.
Embodiment one,
A kind of health products of strengthen immunity, in terms of the health products of 1000 described strengthen immunities, comprise following material And its content: peacilomyce hepiahi bacterium powder 150-250g, American Ginseng, barrenwort and gynostemma pentaphylla extract, filtration, concentrate after dried cream powder 150-250g.The consumption proportion of American Ginseng, barrenwort and gynostemma pentaphylla: American Ginseng 200-300g, barrenwort 500-600g, gynostemma pentaphylla 550-650g.Described composition can be made into tablet, granule, hard capsule or soft capsule.
A kind of preparation method of the health products of strengthen immunity:
Step one, American Ginseng, barrenwort and gynostemma pentaphylla are cleaned, select, and make net medicinal material, plus 10 times amount 75% alcohol reflux Extract 2 times, 2 hours every time, filter, merging filtrate.
Step 2, in -0.065~-0.075mpa, to the filtrate recycling ethanol in step one in the environment of 60 DEG C, concentrate To the clear cream for 1.30-1.35 for the relative density, concentrate Conditions Temperature and be 60 DEG C.
Clear cream in step 3, step 2 is dried under 70 DEG C of vacuum environments, pulverizes, and crosses 80 mesh sieves, prepared dry cream Powder.
Step 4, peacilomyce hepiahi bacterium powder are crossed 80 mesh sieves and peacilomyce hepiahi bacterium fine powder are obtained.
Step 5, by peacilomyce hepiahi bacterium fine powder and step 3 dried cream powder mix 30 minutes, with 80% ethanol system Softwood, crosses 16 mesh sieves and pelletizes, be dried at 60 DEG C, cross 14 mesh sieve whole grains, prepared semi-finished granules.
Step 6, semi-finished granules are sent in capsule filling machine, No. 0 capsule filling, loading amount 0.4g, prepared capsule.Throw After light, during inner packing, outward appearance underproof packaging product is chosen in detection, and the capsule after inner packing is put in storage after quality inspection.
Embodiment two,
A kind of health products of strengthen immunity, in terms of the health products of 1000 described strengthen immunities, comprise following material And its content: peacilomyce hepiahi bacterium powder 200g, American Ginseng, barrenwort and gynostemma pentaphylla extract, filtration, concentrate after dried cream powder 200g.The consumption proportion of American Ginseng, barrenwort and gynostemma pentaphylla: American Ginseng 200-300g, barrenwort 500-600g, gynostemma pentaphylla 550- 650g.Consumption preferred 250g, 550g, 600g of American Ginseng, barrenwort and gynostemma pentaphylla.Composition can be made into tablet, granule, hard Capsule or soft capsule.Preparation method is same as above.
Embodiment three,
A kind of health products of strengthen immunity, in terms of the health products of 1000 described strengthen immunities, comprise following material And its content: peacilomyce hepiahi bacterium powder 200g, American Ginseng, barrenwort and gynostemma pentaphylla extract, filtration, concentrate after dried cream powder 200g.The consumption proportion of American Ginseng, barrenwort and gynostemma pentaphylla: American Ginseng 280g, barrenwort 540g, gynostemma pentaphylla 610g.Composition Can be made into tablet, granule, hard capsule or soft capsule.Preparation method is same as above.
Above the present invention is exemplarily described it is clear that the present invention implements is not subject to the restrictions described above, As long as employing the improvement of various unsubstantialities that method of the present invention design and technical scheme are carried out, or not improved by this Bright design and technical scheme directly apply to other occasions, all within protection scope of the present invention.The protection of the present invention Scope should be defined by the protection domain that claims are limited.

Claims (5)

1. a kind of health products of strengthen immunity are it is characterised in that in terms of the health products of 1000 described strengthen immunities, comprise Following material and its content: peacilomyce hepiahi bacterium powder 150-250g, American Ginseng, barrenwort and gynostemma pentaphylla extract, filter, concentrate Dried cream powder 150-250g afterwards.
2. the health products of strengthen immunity according to claim 1 are it is characterised in that with 1000 described strengthen immunities Health products meter, comprise following material and its content: peacilomyce hepiahi bacterium powder 200g, American Ginseng, barrenwort and gynostemma pentaphylla carry Take, filter, concentrate after dried cream powder 200g.
3. the health products of strengthen immunity according to claim 1 are it is characterised in that described American Ginseng, barrenwort and strand The blue consumption proportion of stock: American Ginseng 200-300g, barrenwort 500-600g, gynostemma pentaphylla 550-650g.
4. strengthen immunity according to claim 1 health products it is characterised in that described composition can be made into tablet, Granule, hard capsule or soft capsule.
5. the preparation method of the health products of strengthen immunity according to claim 1 is it is characterised in that methods described step Including:
Step one, American Ginseng, barrenwort and gynostemma pentaphylla are cleaned, select, and make net medicinal material, plus 10 times amount 75% alcohol reflux extracts 2 times, 2 hours every time, filtration, merging filtrate;
Step 2, to the filtrate recycling ethanol in step one, be concentrated into the clear cream that relative density is 1.30-1.35;
Clear cream in step 3, step 2 is dried under 70 DEG C of vacuum environments, pulverizes, sieves, prepared dried cream powder;
Step 4, peacilomyce hepiahi bacterium powder are crossed 80 mesh sieves and peacilomyce hepiahi bacterium fine powder are obtained;
Step 5, the dried cream powder in peacilomyce hepiahi bacterium fine powder and step 3 is mixed 30 minutes, with 80% ethanol softwood, Sieve granulation, whole grain of sieving after being dried, prepared semi-finished granules;
Step 6, semi-finished granules are sent in capsule filling machine, and capsule is filled, prepared capsule.
CN201610963279.2A 2016-10-28 2016-10-28 Health care product for enhancing immunity and preparation method thereof Pending CN106333987A (en)

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CN106333987A true CN106333987A (en) 2017-01-18

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107279984A (en) * 2017-07-18 2017-10-24 吉林青晨药业有限公司 Technology of preparing with the gentle physical fatigue functional health product of strengthen immunity
CN107647395A (en) * 2017-10-13 2018-02-02 延边韩工坊健康制品有限公司 It is a kind of that there is health food for improving immunity function and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
肖菊芳: "草参固金胶囊生产工艺研究", 《黑龙江医药》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107279984A (en) * 2017-07-18 2017-10-24 吉林青晨药业有限公司 Technology of preparing with the gentle physical fatigue functional health product of strengthen immunity
CN107647395A (en) * 2017-10-13 2018-02-02 延边韩工坊健康制品有限公司 It is a kind of that there is health food for improving immunity function and preparation method thereof

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Application publication date: 20170118