CN102988648A - Medicine for treating gastrointestinal diseases - Google Patents

Abstract

The invention discloses a medicine for treating gastrointestinal diseases. The medicine is prepared through mixing Radix Codonopsis, fried Rhizoma Atractylodis Macrocephalae, Poria cocos, Pinellia Tuber, cortex magnoliae officinalis, Radix Aucklandiae, Fructus Aurantii, Rhizoma Corydalis, Cortex Moutan, Atractylodes lancea, prepared rehmannia root, Achyranthes bidentata, Himalayan Teasel Root, Eucommia ulmoides, Rhizoma Alismatis, Cornus officinalis, Chinese Taxillus Twig and Wrinkled Gianthyssop according to certain proportions. The medicine has the efficacies of spleen invigorating, kidney tonifying, qi moving, stomach harmonizing and pain relieving. The medicine has good curative effects on functional gastrointestinal diseases comprising gastritis, gastric ulcer, duodenal ulcer, duodenitis and the like, and accompanied psychiatric symptoms comprising insomnias, dysphoria and the like, and the effective rates can reach above 98%. The medicine has the advantages of no toxic side effects to human bodies, simple making method, and low cost, can be consumed by general patients, and is an ideal medicine for treating the functional gastrointestinal diseases.

Description

A kind of medicine for the treatment of gastrointestinal disease

Technical field

The present invention relates to a kind of medicine for the treatment of gastrointestinal disease, belong to the field of Chinese medicines.

Background technology

Gastrointestinal disease is common, the frequently-occurring disease of digestive system, its kind is more, as, acute and chronic gastritis, Stomach duodenum ulcer, duodenitis etc., the factors such as many, improper diet irregular due to personal lifestyle occur for it, and feelings will is unsuccessful cause gastrointestinal dysfunction and cause.Clinical main manifestations is anorexia, feel sick and vomiting, stomachache, flatulence, stomachache, abdominal distention, diarrhoea, constipation, have blood in stool, the gastrointestinal symptom such as haematemesis, simultaneously can be accompanied by spiritual aspect symptom, as, insomnia, irritated etc., having a strong impact on people's physical and mental health.Gastrointestinal disease is in the majority with chronic disease, obstinate, and prolonged and repeated outbreak has the possibility that canceration occurs.At present, be used for the treatment of gastrointestinal disease in, western drug is all more, but applicable disease scope is less mostly, and Western medicine also the ubiquity side effect is large, cure the symptoms, not the disease, more after the easy defective of recurrence, there is the unconspicuous deficiency of curative effect mostly in Chinese medicine.Therefore, the medicine of applied widely, the treating both the principal and secondary aspects of a disease of research and development and eutherapeutic treatment gastrointestinal disease seems very necessary.

Summary of the invention

Purpose of the present invention is exactly for above-mentioned disease, and a kind of applied widely, treating both the principal and secondary aspects of a disease and curative effect medicine preferably is provided.

Medicine of the present invention is that the crude drug by following weight parts is mixed:

Radix Codonopsis 25-35 part, Rhizoma Atractylodis Macrocephalae (parched) 25-35 part, Poria 25-35 part,

Rhizoma Pinelliae 25-50 part, Cortex Magnoliae Officinalis 25-35 part, Radix Aucklandiae 15-25 part,

Fructus Aurantii 15-25 part, Rhizoma Corydalis 15-25 part, Cortex Moutan 25-35 part,

Rhizoma Atractylodis 35-45 part, Radix Rehmanniae Preparata 25-35 part, Radix Achyranthis Bidentatae 25-35 part,

Radix Dipsaci 25-35 part, Cortex Eucommiae 25-35 part, Rhizoma Alismatis 25-35 part,

Fructus Corni 25-35 part, Herba Taxilli 25-35 part, Herba Pogostemonis 25-35 part.

In this medicine, the preferred weight proportioning of each crude drug is:

30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts, Poria,

35 parts of the Rhizoma Pinelliaes, 30 parts of Cortex Magnoliae Officinalis, 20 parts of the Radix Aucklandiae,

20 parts of Fructus Aurantiis, 20 parts of Rhizoma Corydalis, 30 parts of Cortex Moutans,

40 parts of Rhizoma Atractylodis, 30 parts, Radix Rehmanniae Preparata, 30 parts of Radix Achyranthis Bidentataes,

30 parts of Radix Dipsaci, 30 parts of the Cortexs Eucommiae, 30 parts of Rhizoma Alismatis,

30 parts of Fructus Corni, 30 parts of Herba Taxillis, 30 parts of Herba Pogostemoniss.

When medicine of the present invention prepared, proportioning was ground into smalls with each crude drug mixing in accordance with regulations, companion and even, and packing is made as powder or loads and is capsule, can Mel be also binding agent, is pill with raw material medicamental pulverata and Mel mixing manufacture.Instructions of taking: every day 3 times, one after each meal contains crude drug 3-6g in each taking dose, and 10 days is a course for the treatment of.The light and onset patient of the state of an illness need take one to two course for the treatment of, and sick of a specified duration and patient with severe symptoms need be used in conjunction three to six courses for the treatment of, and good therapeutic effect can be arranged.

Theory of Chinese medical science is thought, " the kidney being the origin of congenital constitution, the spleen being the foundation of acquired constitution ", " healthy energy deposit in, heresy can not be done ".The present invention is take the strengthening spleen, tonifying kidney medicine as main, and assistant is take the promoting the circulation of QI to relieve pain medicine as auxiliary, in the hope for the treatment of both the principal and secondary aspects of a disease types of functionality gastrointestinal disease.In the present invention's formula, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Radix Dipsaci, the Cortex Eucommiae have the effect of kidney and spleen invigorating QI invigorating, to think monarch drug, be equipped with Poria, Radix Rehmanniae Preparata, Herba Taxilli, Fructus Corni, to strengthen strengthening spleen, tonifying kidney, promote that the body transporting is ministerial drug, and with the Radix Aucklandiae, Fructus Aurantii, Cortex Magnoliae Officinalis, Rhizoma Corydalis promoting the circulation of QI to relieve pain, with the Rhizoma Pinelliae, Rhizoma Atractylodis are drying damp and strengthening spleen, altogether as adjuvant drug, Poria, Radix Achyranthis Bidentatae are returned through for making medicine with priming take Rhizoma Alismatis, Herba Pogostemonis, Cortex Moutan eliminating dampness by diuresis spleen invigorating.All medicines share, and can gather altogether the effect of strengthening spleen, tonifying kidney, relieving QI stagnancy in the stomach pain relieving, the treatment of suitable types of functionality gastrointestinal disease.

Medicine of the present invention all has good therapeutic effect to mental symptoms such as the functional gastrointestinal disorders such as gastritis, Stomach duodenum ulcer, duodenitis and the insomnia of following, agitations.Through selection, 173 routine functional gastrointestinal disorder patient clinicals are observed, concrete outcome is as follows:

(1) physical data: accept altogether 173 routine functional gastrointestinal patients for medical treatment, male 80 examples wherein, female's 93 examples are age 6-72 one full year of life, 43.2 one full year of life of mean age, short number day of the course of disease, the longest 20 years.

(2) diagnostic criteria:

Gastrointestinal disease mostly is chronic disease, on the pathology course of disease, mostly is due to irregular, the improper diet of life, often begins with the mucosa inflammation, is developed to gradually mucosal erosion, even perforation.On symptom, take dyspepsia and pain as principal character and can be with hemorrhage, as, the symptom such as spit blood, have blood in stool, even cause anemia, become thin and weak and sickly.But the clinical manifestation of various concrete diseases has again difference.

Gastritis: dyspepsia, inappetence, flatulence, stomachache, belch acid regurgitation, day are suffered from not having flavor, emaciation and sallow complexion.

Gastric ulcer: except with the gastritis symptom, also with the regular pain of stomach, nausea and vomiting, stool often have haematemesis etc. with black, idol.

Duodenitis: dyspepsia, the regular pain of stomach hypogastric region, the time with diarrhoea etc.

Duodenal ulcer: the pain increased, and often diarrhoea, defecate often with black.

Except having above-mentioned symptom, all patients all further make a definite diagnosis with gastroscope or stomach barium meal.

(3) Therapeutic Method:

Use powder, capsule or the pill of medicine of the present invention according to patient's practical situation, every day 3 times, one after each meal contains crude drug 3-6g in each taking dose, and 10 days is a course for the treatment of.The lighter and onset person use one to two course for the treatment of, and for a long time sick and patient with severe symptoms was used in conjunction for three to six courses for the treatment of.All patients of period in a medicine all cut out other drug, and advise the patient to avoid tea, cigarette, wine and edible peracid food.

(4) efficacy assessment standard:

Cure: clinical symptoms all disappears;

Produce effects: clinical symptoms obviously alleviates;

Effectively: clinical symptoms is alleviated to some extent, is alleviated, but obvious not;

Invalid: as to use continuously six courses for the treatment of, do not reach effective standard person.

All patients all need further to make a definite diagnosis with gastroscope or stomach barium meal.

(5) therapeutic outcome:

Disease	Number of cases	Cure	Produce effects	Effectively	Invalid	Total effective rate
							Chronic gastritis	98	80	9	6	3	97％
Gastric ulcer	17	16	1	0	0	100％
							Duodenitis	32	29	1	1	1	97％
Duodenal ulcer	26	23	2	1	0	100％
							Add up to	173	148	13	8	4	98％

After above-mentioned patient takes medicine of the present invention, follow the mental symptom such as insomnia, agitation of gastrointestinal disease also disappear thereupon or alleviate.In above-mentioned healing patient following up a case by regular visits to after three months, the Relapse rate phenomenon does not all appear.

In a word, in this clinical trial, use Drug therapy gastrointestinal disease 173 examples of the present invention, result is cured 148 examples, produce effects 13 examples, and effective 8 examples, total effective rate reaches 98%.

Model case:

1, Dong Linxia, female, 42 years old, the Hancheng City Xincheng District people of Shaanxi Province, the Hancheng City staff of Government Office.Suffered from gastropathy nearly 20 years, the People's Hospital is diagnosed as chronic gastritis through Hancheng City, and with mental symptoms such as insomnia, agitations, in many ways seeks medical advice invalid, took continuously drug powder of the present invention to cure after six courses for the treatment of in 16 days February in 2009, and in high spirits.

2, Guo Qing, female, 18 years old, Shaanxi Province's Hancheng City gold people from city, Hancheng City Xiangshan Middle School Students.Suffered from gastropathy 3 years, the People's Hospital is diagnosed as chronic gastritis through Hancheng City, took medicine capsule of the present invention and cure after three courses for the treatment of in 10 days March in 2010, so far without recurrence.

3, Chen Yilin: man, 48 years old, peasant, strong people from village in the Hancheng City Xi Zhuan south of a town, Shaanxi Province.Suffer from Stomach duodenum ulcer for many years, xerostomia, bitter taste, nervous agitation, fullness in the chest, frequent micturition, take bolus of drug of the present invention from April 28th, 2009 and cure after 4 courses for the treatment of throughout the year, so far without recurrence.

4, recklessly charge: man, 40 years old, the Shan Xiangshan miner people of Hancheng mineral bureau of coal group.Have a stomach-ache flatulence, constipation for many years, and mine administrative bureau hospital is diagnosed as chronic gastritis through the Hancheng, rises on June 15th, 2009 and takes course for the treatment of of capsule of the present invention, and symptom all disappears.

5, Hu Sirong: man, 46 years old, the Shan Xiangshan miner people of Hancheng mineral bureau of coal group.Suffer from gastropathy for many years, stomachache, flatulence, constipation, mineral bureau is diagnosed as gastric ulcer through the Hancheng, rises on January 28th, 2010 and takes three courses for the treatment of of drug powder of the present invention, and symptom all disappears.

6, Zhang Huilan, female, 49 years old, Hancheng City Xi Zhuan town, Shaanxi Province Xi Zhuan people from village.Suffer from gastropathy, constipation, xerostomia, bitter taste, liver spleen dampness are large, and healthcare hospital for women ﹠ children is diagnosed as gastritis ulcerosa through Hancheng City, take course for the treatment of of bolus of drug of the present invention from 28 days March in 2011, and symptom all disappears.

7, Liu Min: the female, 29 years old, the cadre, the staff is done in Shaanxi Province's Hancheng City new city family planning.Gastropathy, does not feel like a meal at fullness in the chest, and liver spleen dampness is large, frequent micturition, and the second the People's Hospital is diagnosed as chronic gastritis through Hancheng City, takes medicine capsule of the present invention from May 10th, 2010 and cures four courses for the treatment of.

8, model space: man, 18 years old, student, Hancheng City slab bridge town, Shaanxi Province slab bridge people from village.Just rush down, dyspepsia, inappetence, transporting is unable, the People's Hospital is diagnosed as duodenitis through Hancheng City, takes medicine capsule of the present invention from October 6th, 2010 and cures two courses for the treatment of.

Medicine of the present invention has no side effect to human body, and manufacture method is simple, and medicine is with low cost, for extensive patients can bear, is a kind of ideal medicament for the treatment of functional gastrointestinal disorder.

The specific embodiment

The below narrates three embodiment of the present invention:

Embodiment 1

Weighting raw materials Radix Codonopsis 28kg, Rhizoma Atractylodis Macrocephalae (parched) 32kg, Poria 28kg, Rhizoma Pinelliae 45kg, Cortex Magnoliae Officinalis 28kg, Radix Aucklandiae 24kg, Fructus Aurantii 16kg, Rhizoma Corydalis 24kg, Cortex Moutan 26kg, Rhizoma Atractylodis 44kg, Radix Rehmanniae Preparata 28kg, Radix Achyranthis Bidentatae 32kg, Radix Dipsaci 28kg, Cortex Eucommiae 32kg, Rhizoma Alismatis 28kg, Fructus Corni 32kg, Herba Taxilli 28kg, Herba Pogostemonis 32kg.

Preparation method: each crude drug mixing of above-mentioned weight is ground into smalls, crosses 300 mesh sieves, companion and even packs and is made as powder.

Instructions of taking: take after mixing it with water after meal every day 3 times, each serving using crude drug powder 6g, 10 days is a course for the treatment of.

Implementation column 2

Weighting raw materials Radix Codonopsis 34kg, Rhizoma Atractylodis Macrocephalae (parched) 26kg, Poria 34kg, Rhizoma Pinelliae 30kg, Cortex Magnoliae Officinalis 34kg, Radix Aucklandiae 18kg, Fructus Aurantii 22kg, Rhizoma Corydalis 18kg, Cortex Moutan 32kg, Rhizoma Atractylodis 38kg, Radix Rehmanniae Preparata 34kg, Radix Achyranthis Bidentatae 26kg, Radix Dipsaci 34kg, Cortex Eucommiae 26kg, Rhizoma Alismatis 34kg, Fructus Corni 26kg, Herba Taxilli 34kg, Herba Pogostemonis 26kg.

Preparation method: each crude drug mixing of above-mentioned weight is ground into smalls, crosses 200 mesh sieves, companion and even is made as capsule.

Instructions of taking: every day 3 times, one after each meal contains crude drug 4g in each taking dose, and 10 days is a course for the treatment of.

Embodiment 3

Weighting raw materials Radix Codonopsis 30kg, Rhizoma Atractylodis Macrocephalae (parched) 30kg, Poria 30kg, Rhizoma Pinelliae 35kg, Cortex Magnoliae Officinalis 30kg, Radix Aucklandiae 20kg, Fructus Aurantii 20kg, Rhizoma Corydalis 20kg, Cortex Moutan 30kg, Rhizoma Atractylodis 40kg, Radix Rehmanniae Preparata 30kg, Radix Achyranthis Bidentatae 30kg, Radix Dipsaci 30kg, Cortex Eucommiae 30kg, Rhizoma Alismatis 30kg, Fructus Corni 30kg, Herba Taxilli 30kg, Herba Pogostemonis 30kg.

Preparation method: each crude drug of above-mentioned weight is mixed being ground into smalls, crosses 200 mesh sieves, the companion and evenly after and the Mel mixing manufacture be pill.

Instructions of taking: every day 3 times, one after each meal contains crude drug 5g in each taking dose, and 10 days is a course for the treatment of.

Claims (2)

1. a medicine for the treatment of gastrointestinal disease, is characterized in that, it is that crude drug by following weight parts is mixed:

Radix Codonopsis 25-35 part, Rhizoma Atractylodis Macrocephalae (parched) 25-35 part, Poria 25-35 part,

Rhizoma Pinelliae 25-50 part, Cortex Magnoliae Officinalis 25-35 part, Radix Aucklandiae 15-25 part,

Fructus Aurantii 15-25 part, Rhizoma Corydalis 15-25 part, Cortex Moutan 25-35 part,

Rhizoma Atractylodis 35-45 part, Radix Rehmanniae Preparata 25-35 part, Radix Achyranthis Bidentatae 25-35 part,

Radix Dipsaci 25-35 part, Cortex Eucommiae 25-35 part, Rhizoma Alismatis 25-35 part,

Fructus Corni 25-35 part, Herba Taxilli 25-35 part, Herba Pogostemonis 25-35 part.

2. the medicine for the treatment of gastrointestinal disease according to claim 1, is characterized in that, the weight proportion of each crude drug is:

30 parts of Radix Codonopsis, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts, Poria,

35 parts of the Rhizoma Pinelliaes, 30 parts of Cortex Magnoliae Officinalis, 20 parts of the Radix Aucklandiae,

20 parts of Fructus Aurantiis, 20 parts of Rhizoma Corydalis, 30 parts of Cortex Moutans,

40 parts of Rhizoma Atractylodis, 30 parts, Radix Rehmanniae Preparata, 30 parts of Radix Achyranthis Bidentataes,

30 parts of Radix Dipsaci, 30 parts of the Cortexs Eucommiae, 30 parts of Rhizoma Alismatis,

30 parts of Fructus Corni, 30 parts of Herba Taxillis, 30 parts of Herba Pogostemoniss.