CN102961438A - Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 4-8 parts of divaricate saposhnikovia root, 4-8 parts of Chinese angelica, 4-8 parts of root of largeleaf gentian, 4-8 parts of Indian buead and 4-8 parts of liquorice. The preparation method comprises the following steps of: drying the components of the raw materials, dosing according to a weight ratio, uniformly mixing, crushing into the fineness of 100-150 meshes, and performing ultraviolet irradiation and sterilization to obtain the finished product. The traditional Chinese medicine composition is simple in prescription and preparation process, low in cost, good in treatment effect, difficult to recur and small in toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind for the treatment of rheumatism of oral medication and the Chinese medicine composition of rheumatoid arthritis.
Background technology
Rheumatism and rheumatoid arthritis are a kind of common multiple stubborn diseases, belong to the traditional Chinese medical science " arthromyodynia " category.The arthromyodynia Clinical typing is main mainly with wind, cold, wet, hot four types, and wherein the kind migration person of predominant wind is migratory arthralgia, and predominant cold pain person is arthralgia aggravated by cold, and the preponderance of dampness struttuer is damp arthralgia, and section of steam win or whole body heating person are pyretic arthralgia.Modern medicine thinks, rheumatism and rheumatoid pathogenic factors except wind, cold, wet, also comprise infection, immunity, metabolism, endocrine, degeneration, heredity, tumor etc.Because rheumatism and patient with rheumatoid arthritis blood circulation are obstructed, cause muscle to lack nutrition and accelerated ageing, become stiff, severe patient muscle and blood vessel atrophy, some patients were the joint also can occur and disable depleted with viscera function.
The medicament categories for the treatment of rheumatism and rheumatoid arthritis is various at present.Wherein, western medicine has obvious toxic and side effects, is difficult to thorough healing, and drug withdrawal is recurred easily more; Herbal nature is gentle, toxic and side effects is little, good effect, but tcm prescription shows the tendency of ignoring the compatibility of drugs rule in recent years, complicated, the flavour of a drug problem on the high side of ubiquity prescription, the prescription taste of Chinese medicine is too much, complicated component, not only the pharmacy cost increases, and toxic and side effects is bigger than normal, some in addition lead to complications, therapeutic effect is not good enough.
Summary of the invention
For the problems referred to above that prior art exists, the applicant provides through Improvement, and a kind of Chinese medicine composition for the treatment of rheumatism and rheumatoid arthritis and preparation method thereof is provided.Chinese medicine composition composition formula of the present invention and preparation technology are simple, with low cost, and therapeutic effect is good, are difficult for recurrence, and toxic and side effects is little.
Technical scheme of the present invention is as follows:
A kind of Chinese medicine composition for the treatment of rheumatism and rheumatoid arthritis is prepared from by the raw material of following weight parts: 4 ~ 8 parts of Radix Saposhnikoviaes, 4 ~ 8 parts of Radix Angelicae Sinensis, 4 ~ 8 parts of Radix Gentianae Macrophyllae, 4 ~ 8 parts in Poria, 4 ~ 8 parts in Radix Glycyrrhizae.
Preferably, Chinese medicine composition of the present invention is prepared from by the raw material of following weight parts:
6 parts of Radix Saposhnikoviaes, 6 parts of Radix Angelicae Sinensis, 6 parts of Radix Gentianae Macrophyllae, 6 parts in Poria, 6 parts in Radix Glycyrrhizae.
Its further technical scheme is:
The dosage form of described Chinese medicine composition is powder.
The present invention also provides a kind of method for preparing the Chinese medicine composition of above-mentioned treatment rheumatism and rheumatoid arthritis, and step is as follows: with each raw material components oven dry, prepare burden by weight ratio, evenly mixed, be ground into fineness 100 ~ 150 orders, ultraviolet radiation disinfection obtains finished product.
Administrated method: get Chinese drug-treated group compositions 10 g, water decocts at every turn, every day sooner or later each once, one after each meal, one month is a course for the treatment of.
The technique effect that the present invention is useful is:
Disadvantage for existing rheumatism and the existence of rheumatoid arthritis treatment method, be that the western medicine toxic and side effects is large, easily recurrence, the treatment by Chinese herbs prescription is complicated, flavour of a drug are on the high side, curative effect is not good enough, the inventor is according to Compound Cormpatibility Law of Traditional Chinese Medical Science, on the basis of original treatment rheumatism and rheumatoid arthritis Chinese medicine recipe " Radix Angelicae Pubescentis et Herba Taxilli Decoction " and " Ledebouriellae Decoction ", choose the Same Chinese Herbal Medicine composition that plays the primary treatment effect in the two, " go different depositing together ", " abbreviation " only comprised Chinese medicine of the five flavours (Radix Saposhnikoviae, Radix Angelicae Sinensis, Radix Gentianae Macrophyllae, Poria, Radix Glycyrrhizae) compositions.This Chinese medicine composition composition formula and preparation technology are simple, have not only kept the effect of simplifying front former compound recipe promoting blood circulation to remove obstruction in the collateral, expelling wind and removing dampness, Shujin analgesia, and have greatly reduced the pharmacy cost, therapeutic effect is good, be difficult for recurrence, toxic and side effects is little, the risk of having avoided flavour of a drug too much easily to lead to complications; Clinical efficacy shows that Chinese medicine composition mean treatment effective percentage of the present invention reaches 100%.
The specific embodiment
Below in conjunction with embodiment, the embodiment that the present invention is concrete is described.
Embodiment 1
The present embodiment Chinese medicine composition is prepared from by the raw material of following weight parts: 4 parts of Radix Saposhnikoviaes, 5 parts of Radix Angelicae Sinensis, 7 parts of Radix Gentianae Macrophyllae, 5 parts in Poria, 5 parts in Radix Glycyrrhizae.
Preparation method: with above-mentioned each raw material components oven dry, prepare burden by weight ratio, mix homogeneously is ground to 100 orders with grinder with compound, and Burdick lamp illumination-based disinfection 2 h obtain the powder finished product.
Above-mentioned each component drug is as shown in table 1 by weight.
Embodiment 2
Each component drug is as shown in table 1 by weight.
Preparation method: with above-mentioned each raw material components oven dry, prepare burden by weight ratio, mix homogeneously is ground to 120 orders with grinder with compound, and Burdick lamp illumination-based disinfection 2 h obtain the powder finished product.
Embodiment 3
Each component drug is as shown in table 1 by weight.
Preparation method: with above-mentioned each raw material components oven dry, prepare burden by weight ratio, mix homogeneously is ground to 140 orders with grinder with compound, and Burdick lamp illumination-based disinfection 2 h obtain the powder finished product.
Embodiment 4
Each component drug is as shown in table 1 by weight.
Preparation method: with above-mentioned each raw material components oven dry, prepare burden by weight ratio, mix homogeneously is ground to 140 orders with grinder with compound, and Burdick lamp illumination-based disinfection 2 h obtain the powder finished product.
Embodiment 5
Each component drug is as shown in table 1 by weight.
Preparation method: with above-mentioned each raw material components oven dry, prepare burden by weight ratio, mix homogeneously is ground to 150 orders with grinder with compound, and Burdick lamp illumination-based disinfection 2 h obtain the powder finished product.
Table 1
Clinical effectiveness
1. patient's overview
Chinese medicine composition of the present invention is used for the treatment of 50 routine rheumatism and patient with rheumatoid arthritis, male 35 examples wherein, women 15 examples; Age reckling 35 years old, the maximum 71 years old; The course of disease is the shortest 5 months, and is the longest 20 years.
The diagnostic criteria that American Rheumatism Association formulates in 1987 is adopted in the diagnosis of rheumatism and rheumatoid arthritis:
(1) refuses to budge continuous 1 hour (every day) at least 6 weeks of the course of disease morning at least;
(2) 3 or 3 above arthroncuss are arranged, continued at least 6 weeks;
(3) wrist, the palm refer to, nearly articulations digitorum manus swelling, continued at least 6 weeks;
(4) symmetry arthroncus;
(5) subcutaneous rheumatoid nodules is arranged;
(6) positive (titre＞1:20) of rheumatoid factor;
(7) detecting the confirmation finger-joint through x-ray changes;
Meeting above-mentioned 4 or 4 above persons can make a definite diagnosis.
Above-mentioned 50 routine patients are divided into 5 groups, every group of 10 patients, each organizes 7 of male patients, women patient 3
Name, the age random distribution.
2. treat respectively above-mentioned 5 groups of patients with embodiment 1 ~ embodiment 5 made finished products, administrated method such as front institute
State, treat continuously two courses for the treatment of.
3. criterion of therapeutical effect
In conjunction with clinical symptoms, the sign of rheumatism and rheumatoid arthritis, and with reference to " traditional Chinese medical science disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine implemented in 1994, draft as follows:
Stiff disappearance in recovery from illness---morning, the pain and swelling phenomenon disappears, and joint function recovery is without any sequela;
Stiff disappearance in produce effects---morning, pain and swelling disappears substantially, and function of joint is obviously improved, and can take part in the work;
Take a turn for the better---stiff alleviation in morning, pain takes a turn for the better, and arthroncus alleviates, and can participate in suitable physical work;
Invalid---arthritic symptom, sign are all without obviously improving.
4. therapeutic effect
5 groups of patients' curative effect statistical result is referring to table 1.
As shown in Table 1, with traditional Chinese medicine composition for treating rheumatism of the present invention and patient with rheumatoid arthritis 50 examples, 50 examples all effectively, none invalid patient, 5 groups of patient's average effectiveness levels reach 100%, have no any untoward reaction, above-mentioned recovery from illness patient proves that in the phenomenon of following up a case by regular visits to that no case was recurrence in half a year Chinese medicine composition of the present invention has good curative effect.
Embodiment 1 ~ embodiment 5 related each raw material are the commercially available prod.
Above-described only is preferred implementation of the present invention, the invention is not restricted to above embodiment.Be appreciated that other improvement and variation that those skilled in the art directly derive or associate under the prerequisite that does not break away from basic conception of the present invention, all should think to be included within protection scope of the present invention.
Claims (4)
1. a Chinese medicine composition for the treatment of rheumatism and rheumatoid arthritis is characterized in that being prepared from by the raw material of following weight parts: 4 ~ 8 parts of Radix Saposhnikoviaes, 4 ~ 8 parts of Radix Angelicae Sinensis, 4 ~ 8 parts of Radix Gentianae Macrophyllae, 4 ~ 8 parts in Poria, 4 ~ 8 parts in Radix Glycyrrhizae.
2. the Chinese medicine composition of described treatment rheumatism and rheumatoid arthritis according to claim 1 is characterized in that being prepared from by the raw material of following weight parts: 6 parts of Radix Saposhnikoviaes, 6 parts of Radix Angelicae Sinensis, 6 parts of Radix Gentianae Macrophyllae, 6 parts in Poria, 6 parts in Radix Glycyrrhizae.
3. the Chinese medicine composition of each described treatment rheumatism and rheumatoid arthritis according to claim 1 ~ 2, the dosage form that it is characterized in that described Chinese medicine composition is powder.
4. the preparation method of the Chinese medicine composition of the described treatment rheumatism of claim 3 and rheumatoid arthritis is characterized in that step is as follows:, prepare burden by weight ratio each raw material components oven dry, evenly mixed, be ground into fineness 100 ~ 150 orders, the irradiation under ultraviolet ray sterilization obtains finished product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720800A (en) * | 2013-12-30 | 2014-04-16 | 青岛市市立医院 | Inflammation-diminishing pain-relieving compound traditional Chinese medicinal composition for treating rheumatic diseases |
| CN108785396A (en) * | 2017-04-26 | 2018-11-13 | 上海健康医学院 | A kind of Chinese medicine composition and preparation method thereof for treating rheumatism and rheumatoid arthritis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861187A (en) * | 2006-04-05 | 2006-11-15 | 刘少华 | Medicated wine for treating rheumatosis and osteoarthropathy |
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- 2012-11-14 CN CN201210454946.6A patent/CN102961438B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861187A (en) * | 2006-04-05 | 2006-11-15 | 刘少华 | Medicated wine for treating rheumatosis and osteoarthropathy |
Non-Patent Citations (1)
| Title |
|---|
| 王立忠: "《痹证辨治用药》", 《中国中医药报》, 13 December 2006 (2006-12-13), pages 006 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103720800A (en) * | 2013-12-30 | 2014-04-16 | 青岛市市立医院 | Inflammation-diminishing pain-relieving compound traditional Chinese medicinal composition for treating rheumatic diseases |
| CN103720800B (en) * | 2013-12-30 | 2016-02-03 | 青岛市市立医院 | A kind of anti-inflammatory analgetic compound traditional Chinese medicine composite for the treatment of rheumatism disease disease |
| CN108785396A (en) * | 2017-04-26 | 2018-11-13 | 上海健康医学院 | A kind of Chinese medicine composition and preparation method thereof for treating rheumatism and rheumatoid arthritis |
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| CN102961438B (en) | 2014-12-03 |
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