CN103720800A - Anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases - Google Patents

Anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases Download PDF

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CN103720800A
CN103720800A CN201310744179.7A CN201310744179A CN103720800A CN 103720800 A CN103720800 A CN 103720800A CN 201310744179 A CN201310744179 A CN 201310744179A CN 103720800 A CN103720800 A CN 103720800A
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rheumatic diseases
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CN103720800B (en
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孟静
邹树红
宋锋
王燕
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Qingdao Municipal Hospital
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Abstract

The invention relates to an anti-inflammation and pain-relieving compound traditional Chinese medicine composition for treating rheumatism. The compound traditional Chinese medicine composition for treating rheumatic diseases is prepared from the following components, by weight, 5-15 parts of divaricate saposhnikovia root, 7-17 parts of large-leaved gentian, 10-20 parts of wooly datchmanspipe herb, 10-20 parts of lysimachia foenum-graecum, 10-20 parts of Chinese angelica, 7-17 parts of red paeony root, 15-25 parts of poria cocos, 10-20 parts of notopterygium root, 7-17 parts of radix angelicae pubescentis, 7-17 parts of cassia twig, 12-18 parts of radix clematidis, 19-29 parts of astragalus membranaceus, 25-35 parts of honeysuckle flower and 3-8 parts of liquorice. The medicines in the formula are compatible, have assistant and guide effects and are assisted together, so that the medicine has the effects of quickly diminishing swelling and relieving pain, relieving the exterior syndrome, and dispelling wind and removing dampness, can gradually improve the disease resistance of a human body, enhance the physical strength, increase the bone density and enhance the immunity, and finally achieves the effects of treating both symptoms and root causes and eradicating chronic diseases at the same time.

Description

一种治疗风湿类病症的消炎止痛复方中药组合物Anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases

技术领域technical field

本发明涉及一种治疗风湿类病症的消炎止痛复方中药组合物。The invention relates to a compound traditional Chinese medicine composition for reducing inflammation and relieving pain for treating rheumatic diseases.

背景技术Background technique

风湿类风湿关节炎、股骨头坏死、强直性脊椎炎、骨质增生、腰间盘突出、坐骨神经痛、肩周炎、静脉炎、脉管炎及各种顽固性疼痛、麻木、酸沉、肿胀、紧硬、凉冷热等均属祖国中医的痹症范围。西医认为人体免疫功能低下,中医认为人体的体质虚弱,加上外受风寒湿热等邪气的侵袭是本病发展的重要原因。受风邪重者叫行痹,特点是全身患痛遇风寒湿或阴雨天气痛处加重;遇热则缓解;受湿邪重叫着痹。特点是疼痛部位有酸沉重感,肿胀或关节有积水,呈淡黄色。从目前来说,国际医学界对风湿类风湿病的发病原因至今不明,而部分专家认为人体自身免疫功能低下,是本病发生发展的原因。现针对治疗风病类病症,西医一般使用激素类药物,已达到止痛消炎的目的,这种药物只能解表,并不治本,一旦再受风寒湿热、劳累,七情及其它原因,立即复发。病情反复发作导致病人体质更弱,病情更重。中医治疗也不过采用传统治疗方法,如用些姜、附子、川草乌、马钱子之类药物、辛燥克代过度,而长期服用会导致脾胃肝肾受损伤严重。Rheumatic rheumatoid arthritis, femoral head necrosis, ankylosing spondylitis, hyperosteogeny, lumbar disc herniation, sciatica, frozen shoulder, phlebitis, vasculitis and various intractable pain, numbness, acidity, swelling Tightness, tightness, coldness and heat, etc. all belong to the scope of arthralgia in traditional Chinese medicine. Western medicine believes that the immune function of the human body is low, while traditional Chinese medicine believes that the human body's physical weakness, coupled with the invasion of evil forces such as wind, cold, damp and heat, is an important reason for the development of this disease. Those who are severely affected by wind pathogens are called Xingbi, which is characterized by pain in the whole body that is aggravated by wind, cold and damp or cloudy and rainy weather; it is relieved by heat; It is characterized by soreness and heaviness in the painful area, swelling or fluid accumulation in the joints, which is pale yellow in color. For now, the cause of rheumatoid rheumatoid disease is still unknown in the international medical community, and some experts believe that the low immune function of the human body is the reason for the occurrence and development of this disease. Now for the treatment of rheumatic diseases, western medicine generally uses hormone drugs, which have achieved the purpose of pain relief and anti-inflammation. This kind of medicine can only relieve the symptoms, but not cure the root cause. Once it is affected by wind, cold, damp heat, fatigue, seven emotions and other reasons, it will relapse immediately. . Repeated attacks of the disease lead to weaker constitution of the patient and worse condition. Traditional Chinese medicine treatment only uses traditional treatment methods, such as ginger, aconite, chuancaowu, and nuxychonzi, and excessive pungent dryness can cause serious damage to the spleen, stomach, liver and kidneys.

发明内容Contents of the invention

本发明要解决的技术问题是如何克服现有技术的上述缺陷,提供一种治疗风湿类病症的消炎止痛复方中药组合物。The technical problem to be solved by the present invention is how to overcome the above-mentioned defects of the prior art, and provide a compound Chinese medicine composition of anti-inflammatory and pain-relieving for treating rheumatic diseases.

为解决上述技术问题,本治疗风湿类病症的消炎止痛复方中药组合物由以下组分按照所示重量份比例范围配制,防风5~15份、秦艽7~17份、寻骨风10~20份、追地风10~20份、当归10~20份、赤芍7~17份、茯苓15~25份、羌活10~20份、独活7~17份、桂枝7~17份、威灵仙12~18份、黄芪19~29份、银花25~35份、甘草3~8份。In order to solve the above-mentioned technical problems, the anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases is prepared from the following components according to the range of weight parts shown: 5-15 parts of Fangfeng, 7-17 parts of Gentiana chinensis, and 10-20 parts of Xugufeng . 12-18 parts, 19-29 parts of astragalus, 25-35 parts of silver flower, 3-8 parts of licorice.

作为优选配比范围,所述中药组合物由以下组分按照所示重量份比例范围配制,防风9~11份、秦艽11~13份、寻骨风14~16份、追地风14~16份、当归14~16份、赤芍11~13份、茯苓19~21份、羌活14~16份、独活11~13份、桂枝11~13份、威灵仙14~16份、黄芪23~25份、银花29~31份、甘草5~7份。As a preferred proportioning range, the traditional Chinese medicine composition is prepared from the following components according to the proportion range shown in parts by weight: 9-11 parts of Fangfeng, 11-13 parts of Gentiana chinensis, 14-16 parts of Xugufeng, 14-14 parts of Zuidifeng 16 parts, Angelica 14-16 parts, Radix Paeoniae Rubra 11-13 parts, Poria cocos 19-21 parts, Notopterygium 14-16 parts, Duhuo 11-13 parts, Guizhi 11-13 parts, Clematis 14-16 parts, Astragalus 23-25 parts, Yinhua 29-31 parts, licorice 5-7 parts.

作为优选配比,所述中药组合物由以下组分按照所示重量份比例配制,防风15份、秦艽7份、寻骨风20份、追地风10份、当归20份、赤芍7份、茯苓25份、羌活10份、独活17份、桂枝7份、威灵仙18份、黄芪19份、银花35份、甘草3份。As a preferred proportion, the traditional Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 15 parts of Fangfeng, 7 parts of Gentiana chinensis, 20 parts of Xugufeng, 10 parts of Zhuidifeng, 20 parts of Angelica sinensis, 7 parts of Radix Paeoniae Rubra 25 parts of Poria, 10 parts of Notopterygium, 17 parts of Duhuo, 7 parts of Guizhi, 18 parts of Clematis, 19 parts of Astragalus, 35 parts of Silver Flower, and 3 parts of Licorice.

作为优选配比,所述中药组合物由以下组分按照所示重量份比例配制,中药组合物由以下组分按照所示重量份比例范围配制,防风5份、秦艽17份、寻骨风10份、追地风20份、当归10份、赤芍17份、茯苓15份、羌活20份、独活7份、桂枝17份、威灵仙12份、黄芪29份、银花25份、甘草8份。As a preferred proportioning ratio, the Chinese medicine composition is prepared from the following components according to the proportions shown in parts by weight, and the Chinese medicine composition is prepared from the following components according to the proportions shown in parts by weight: 5 parts of Fangfeng, 17 parts of Gentiana chinensis, 17 parts of Xugufeng 10 parts, 20 parts of chasing wind, 10 parts of angelica, 17 parts of red peony root, 15 parts of Poria cocos, 20 parts of notopterygium, 7 parts of duhuo, 17 parts of cassia twig, 12 parts of clematis, 29 parts of astragalus, 25 parts of silver flower, 8 parts of licorice.

作为进一步优选配比,所述中药组合物由以下组分按照所示重量份比例配制,防风11份、秦艽11份、寻骨风16份、追地风14份、当归16份、赤芍11份、茯苓19份、羌活14份、独活13份、桂枝11份、威灵仙14份、黄芪23份、银花31份、甘草5份。As a further preferred proportion, the traditional Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 11 parts of Fangfeng, 11 parts of Gentiana chinensis, 16 parts of Xugufeng, 14 parts of Zhuidifeng, 16 parts of Angelica sinensis, and Radix Paeoniae Rubra 11 parts, Poria cocos 19 parts, Notopterygium 14 parts, Duhuo 13 parts, Guizhi 11 parts, Clematis 14 parts, Astragalus 23 parts, Silver Flower 31 parts, Licorice 5 parts.

作为进一步优选配比,所述中药组合物由以下组分按照所示重量份比例配制,防风9份、秦艽13份、寻骨风14份、追地风16份、当归14份、赤芍13份、茯苓21份、羌活16份、独活11份、桂枝13份、威灵仙16份、黄芪25份、银花29份、甘草7份。As a further preferred proportion, the Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 9 parts of Fangfeng, 13 parts of Gentiana chinensis, 14 parts of Xugufeng, 16 parts of Zhuidifeng, 14 parts of Angelica sinensis, and Radix Paeoniae Rubra 13 parts, Poria cocos 21 parts, Notopterygium 16 parts, Duhuo 11 parts, Guizhi 13 parts, Clematis 16 parts, Astragalus 25 parts, Silver Flower 29 parts, Licorice 7 parts.

作为最佳配比,所述中药组合物由以下组分按照所示重量份比例配制,防风10份、秦艽12份、寻骨风15份、追地风15份、当归15份、赤芍12份、茯苓20份、羌活15份、独活12份、桂枝12份、威灵仙15份、黄芪24份、银花30份、甘草6份。As the optimal ratio, the Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 10 parts of Fangfeng, 12 parts of Gentiana chinensis, 15 parts of Xugufeng, 15 parts of Zhuidifeng, 15 parts of Angelica sinensis, and 12 parts of Radix Paeoniae Rubra. 20 parts of Poria cocos, 15 parts of Notopterygium, 12 parts of Duhuo, 12 parts of Guizhi, 15 parts of Clematis, 24 parts of Astragalus, 30 parts of Silver Flower, and 6 parts of Licorice.

作为优选配方量,所述中药组合物每付配方为,防风10g、秦艽12g、寻骨风15g、追地风15g、当归15g、赤芍12g、茯苓20g、羌活15g、独活12g、桂枝12g、威灵仙15g、黄芪24g、银花30g、甘草6g。As a preferred formula quantity, each formula of the Chinese medicine composition is: Fangfeng 10g, Gentiana 12g, Xugufeng 15g, Zuidifeng 15g, Angelica 15g, Radix Paeoniae Rubra 12g, Poria cocos 20g, Notopterygium 15g, Duhuo 12g, Guizhi 12g , Clematis 15g, Astragalus 24g, Silver Flower 30g, Licorice 6g.

本治疗风湿类病症的消炎止痛复方中药组合物剂型为汤剂,其制备方法为,按上述的重量份比例或配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂。The dosage form of the anti-inflammatory and pain-relieving compound traditional Chinese medicine composition for treating rheumatic diseases is decoction, and its preparation method is as follows: each component is measured according to the above-mentioned weight ratio or formula, each component is pulverized and ground, and then passed through a 100-200 mesh sieve, To obtain mixed powder, add vinegar to the mixed powder and fry it to dryness, add water to decoct for 3-5 hours, filter to get medicinal soup, and obtain the decoction of anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases.

药理分析Pharmacological analysis

防风:味辛、甘,性微温;膀胱、肺、脾、肝经;祛风解表、胜湿止痛、解痉、止痒。Fangfeng: pungent, sweet, slightly warm in nature; bladder, lung, spleen, liver meridians; expelling wind and relieving exterior syndrome, eliminating dampness and relieving pain, relieving spasm, and relieving itching.

秦艽:味辛、苦,性微寒;归胃、肝、胆经;袪风湿、舒筋络、清虚热、清湿热,用于风湿痹痛、中风不遂、筋脉拘挛、骨节酸痛、日晡潮热、小儿疳积发热、湿热黄疸。Gentiana chinensis: pungent in taste, bitter, slightly cold in nature; returns stomach, liver, gallbladder meridian; eliminates rheumatism, relaxes tendons and collaterals, clears deficiency-heat, clears damp-heat, and is used for rheumatism arthralgia, apoplexy, spasm of tendons, arthralgia, day-to-day Morning hot flashes, malnutrition fever in children, damp heat jaundice.

寻骨风:味辛、苦,性平;归肝、胃经;祛风除湿,活血通络,止痛,主风湿痹痛、肢体麻木、筋骨拘挛、脘腹疼痛、跌打伤痛、外伤出血、乳痈及多种化脓性感染、腹痛,疟疾。Xungufeng: pungent, bitter, neutral in nature; returns to the liver and stomach meridians; expelling wind and dampness, promoting blood circulation and dredging collaterals, relieving pain, mainly governing rheumatic arthralgia, numbness of limbs, spasms of muscles and bones, abdominal pain, bruises, traumatic bleeding , breast carbuncle and a variety of suppurative infections, abdominal pain, malaria.

追地风:味辛、涩,性温;归膀胱、肾经;祛风除湿,行气止痛,用于风湿痹痛,腰肌劳损。Chasing ground wind: acrid in the mouth, puckery, warm in nature; Return bladder, kidney meridian; Expelling wind and removing dampness, promoting the flow of qi and relieving pain, used for rheumatic arthralgia, lumbar muscle strain.

当归:性温,味甘、辛,归肝、心、脾经;补血活血,调经止痛,润肠通便;用于血虚萎黄、眩晕心悸、月经不调、经闭痛经、虚寒腹痛、肠燥便秘、风湿痹痛、跌扑损伤和痈疽疮疡等症。Angelica: warm in nature, sweet in taste, pungent, returns to liver, heart, spleen meridian; nourishes blood and activates blood, regulates menstruation and relieves pain, moistens bowel and relieves constipation; used for blood deficiency and chlorosis, dizziness and palpitations, irregular menstruation, amenorrhea dysmenorrhea, abdominal pain due to deficiency and cold, Intestinal dryness and constipation, rheumatic arthralgia, injury from falls, and carbuncle sores and other diseases.

赤芍:味苦,微寒;归肝经;清热凉血,活血祛瘀,行瘀、止痛、凉血、消肿。Radix Paeoniae Rubra: Bitter in the mouth, be slightly cold; Return Liver Meridian; Clear away heat and cool blood, promote blood circulation and remove blood stasis, promote blood stasis, relieve pain, cool blood, detumescence.

茯苓:味甘、淡,性平。归心经、肺经、脾经、肾经。小便不利;水肿胀满;痰饮咳逆;呕吐;脾虚食少;泄泻;心悸不安;失眠健忘;遗精白浊。Poria cocos: sweet in taste, light in taste, flat in nature. Guixin Channel, Lung Channel, Spleen Channel, Kidney Channel. Difficulty urinating; edema and fullness; phlegm and fluid retention and cough; vomiting; spleen deficiency and lack of food; diarrhea; palpitations and restlessness; insomnia and forgetfulness;

羌活:味苦,微寒。归肝经。功能主治:清热凉血,散瘀止痛。用于温毒发斑,吐血衄血,目赤肿痛,肝郁胁痛,经闭痛经,症瘕腹痛,跌扑损伤,痈肿疮疡。Notopterygium: bitter in taste, slightly cold. Return liver channel. Functions and indications: clearing away heat and cooling blood, dissipating blood stasis and relieving pain. It is used for warming and poisoning spots, vomiting blood and epistaxis, conjunctival congestion and swelling pain, liver depression and hypochondriac pain, amenorrhea dysmenorrhea, abdominal pain in the abdomen, injury from falls, carbuncle sores.

独活:味辛、苦,微温;归肝、肾、膀胱经;祛风胜湿,散寒止痛,用于风寒湿痹、腰膝疼痛、少阴伏风头痛、头痛齿痛。Independence Liver: pungent in the mouth, bitter, tepor; Return liver, kidney, urinary bladder meridian; Expelling wind and dampness, dispersing cold and relieving pain, used for anemofrigid-damp arthralgia, waist and knee pain, Shaoyin volt wind headache, headache and toothache.

桂枝:味辛、甘,性温;归膀胱、心、肺经;发汗解肌、温经通络。Cinnamomum twig: spicy, sweet, warm in nature; returns to bladder, heart, and lung meridian; sweats and relieves muscles, warms meridian and dredges collaterals.

威灵仙:味苦,温,无毒;归膀胱经;辛散善走,性温通利能通行十二经,即可驱在表之风又能化在里之湿,通经达络,可导可宣为痛风之要药。Clematis: Bitter, warm, non-toxic; belongs to the bladder meridian; pungent and easy to walk, warm in nature and beneficial to the twelve meridians, can dispel the wind on the surface and dissolve the dampness in the inside, dredge the meridian and reach the collaterals, and can be cured Dao can be declared as the key medicine for gout.

黄芪:味苦,性寒,归肺、胆、脾、大肠、小肠经;具有清热燥湿、泻火解毒、止血和安胎等功效;临床应用表明黄芩抗菌效果比黄连还好,而且不产生抗药性。Astragalus: Bitter in taste, cold in nature, it returns to the lung, gallbladder, spleen, large intestine, and small intestine meridian; it has the effects of clearing away heat and dampness, purging fire and detoxification, hemostasis and anti-abortion; clinical application shows that the antibacterial effect of Scutellaria baicalensis is better than that of Coptis chinensis, and it does not produce drug resistance.

银花:味甘,性寒;归肺、心、胃经;清热解毒,凉散风热,用于痈肿疔疮,喉痹,丹毒,热血毒痢,风热感冒,温病发热。Silver Flower: sweet in the mouth, cold in nature; Return lung, heart, stomach meridian; Heat-clearing and toxic substances removing, dispelling wind-heat, is used for carbuncle furuncle, sore throat, erysipelas, toxic dysentery due to pyretic blood, wind-heat cold, febrile disease heating.

甘草:味甘,性平;入脾、胃、肺经;补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药,用于脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性。Licorice root: sweet in taste, flat in nature; enters the spleen, stomach, and lung meridian; invigorates the spleen and replenishes qi, clears heat and detoxifies, eliminates phlegm and relieves cough, relieves spasm and relieves pain, harmonizes various medicines, used for weak spleen and stomach, fatigue, palpitation, shortness of breath, cough with excessive phlegm, Convulsion and acute pain in the abdomen and limbs, carbuncle and sore, relieve drug toxicity and potency.

本发明一种治疗风湿类病症的消炎止痛复方中药组合物以防风、秦艽、寻骨风、追地风为君药,以当归、赤芍、茯苓、羌活、独活为臣药,以桂枝、威灵仙、黄芪、银花、甘草为佐使药配制而成;方中诸药配伍、君臣协力、佐使共辅,使得本药具有快速消肿止痛的作用,先解其表,并以祛风除湿为目的,能够逐步提高人体抗病能力,增强体力,增加骨密度,增加免疫力的效果,最终达完成标本兼治、双管齐下根除顽疾。An anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases of the present invention uses Fangfeng, Gentiana chinensis, Xugufeng and Zhuidifeng as monarch drugs; Clematis, astragalus, silver flower, and licorice are formulated as adjuvant medicines; the compatibility of all the medicines in the prescription, the cooperation of monarchs and ministers, and the adjuvant and envoy make this medicine have the effect of quickly reducing swelling and relieving pain. The purpose of expelling wind and dampness can gradually improve the human body's disease resistance, enhance physical strength, increase bone density, and increase immunity, and finally achieve the goal of treating both symptoms and root causes and eradicating stubborn diseases with a two-pronged approach.

具体实施方式Detailed ways

实施例1:按防风15g、秦艽7g、寻骨风20g、追地风10g、当归20g、赤芍7g、茯苓25g、羌活10g、独活17g、桂枝7g、威灵仙18g、黄芪19g、银花35g、甘草3g的配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂A。Example 1: Press Fangfeng 15g, Gentiana chinensis 7g, Xugufeng 20g, Zhuidifeng 10g, Angelica 20g, Chishao 7g, Poria cocos 25g, Notopterygium 10g, Duhuo 17g, Guizhi 7g, Clematis 18g, Astragalus 19g, silver The formula of flower 35g and licorice 3g measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water to decoct for 3-5 hours, filter Take the medicine decoction to obtain the decoction A of the anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases.

实施例2:按防风5g、秦艽17g、寻骨风10g、追地风20g、当归10g、赤芍17g、茯苓15g、羌活20g、独活7g、桂枝17g、威灵仙12g、黄芪29g、银花25g、甘草8g的配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂B。Example 2: Press Fangfeng 5g, Gentiana chinensis 17g, Xugufeng 10g, Zhuidifeng 20g, Angelica 10g, Chishao 17g, Poria 15g, Notopterygium 20g, Duhuo 7g, Guizhi 17g, Clematis 12g, Astragalus 29g, silver The formula of flower 25g and licorice 8g measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water to decoct for 3-5 hours, filter Take the medicine decoction to get the decoction B of the anti-inflammatory and pain-relieving compound traditional Chinese medicine composition for treating rheumatic diseases.

实施例3:按防风11g、秦艽11g、寻骨风16g、追地风14g、当归16g、赤芍11g、茯苓19g、羌活14g、独活13g、桂枝11g、威灵仙14g、黄芪23g、银花31g、甘草5g的配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂C。Example 3: Press Fangfeng 11g, Gentiana chinensis 11g, Xugufeng 16g, Zhuidifeng 14g, Angelica 16g, Chishao 11g, Poria cocos 19g, Notopterygium 14g, Duhuo 13g, Guizhi 11g, Clematis 14g, Astragalus 23g, silver The formula of flower 31g and licorice 5g measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water to decoct for 3-5 hours, filter Take the medicine decoction to get the anti-inflammatory and pain-relieving compound Chinese medicine composition decoction C for the treatment of rheumatic diseases.

实施例4:按防风9g、秦艽13g、寻骨风14g、追地风16g、当归14g、赤芍13g、茯苓21g、羌活16g、独活11g、桂枝13g、威灵仙16g、黄芪25g、银花29g、甘草7g的配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂D。Example 4: Press Fangfeng 9g, Gentiana 13g, Xugufeng 14g, Zhuidifeng 16g, Angelica 14g, Chishao 13g, Poria cocos 21g, Notopterygium 16g, Duhuo 11g, Guizhi 13g, Clematis 16g, Astragalus 25g, silver The formula of flower 29g and licorice 7g measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water to decoct for 3-5 hours, filter Take the medicine decoction to obtain the decoction D of the anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases.

实施例5:按防风10g、秦艽12g、寻骨风15g、追地风15g、当归15g、赤芍12g、茯苓20g、羌活15g、独活12g、桂枝12g、威灵仙15g、黄芪24g、银花30g、甘草6g的配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂E。Example 5: Press Fangfeng 10g, Gentiana chinensis 12g, Xugufeng 15g, Zhuidifeng 15g, Angelica 15g, Chishao 12g, Poria cocos 20g, Notopterygium 15g, Duhuo 12g, Guizhi 12g, Clematis 15g, Astragalus 24g, silver The formula of flower 30g and licorice 6g measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water to decoct for 3-5 hours, filter Take the medicine decoction to get the anti-inflammatory and pain-relieving compound Chinese medicine composition decoction E for treating rheumatic diseases.

其中,实施例5制备的治疗风湿类病症的消炎止痛复方中药组合物汤剂E临床应用效果最佳,故为实施例5最佳实施例。Among them, the anti-inflammatory and analgesic compound Chinese medicine composition decoction E prepared in Example 5 for the treatment of rheumatic diseases has the best clinical application effect, so it is the best example of Example 5.

临床资料clinical information

对400例患者进行治疗观察,以证明本发明的药物对各类风湿类风湿疼痛的患者都有独到疗效,400 routine patients are treated and observed, to prove that the medicine of the present invention has a unique curative effect on patients with various types of rheumatic rheumatoid pain,

Figure BDA0000449329390000071
Figure BDA0000449329390000071

全部病例患者临床观察未见任何不良反应。No adverse reaction was found in clinical observation of all cases and patients.

综上所述,本发明一种治疗风湿类病症的消炎止痛复方中药组合物是有效且安全的药物。To sum up, the anti-inflammatory and analgesic compound traditional Chinese medicine composition of the present invention is an effective and safe medicine for treating rheumatic diseases.

典型病例:Typical cases:

病例1:孙某,男,70岁,2009年初诊全身关节肿痛,辗转北京、上海治疗半年病愈加重,四肢关节强直,长期不能行走,失去劳动能力。X线片显示双侧骶髂关节破坏,髋关节间隙明显变窄,诊断为风湿顽痹,服用本实施例5制得的治疗风湿类病症的消炎止痛复方中药组合物汤剂E一个月的治疗,关节肿痛渐消、功能恢复,生活自理,跟踪调查,停药2年未见复发。Case 1: Mr. Sun, male, 70 years old, was first diagnosed with joint swelling and pain all over his body in 2009. After being treated in Beijing and Shanghai for half a year, his condition worsened. X-ray film shows bilateral sacroiliac joint destruction, hip joint space obviously narrows, and is diagnosed as rheumatic impediment, takes the anti-inflammatory analgesic compound Chinese medicine composition decoction E of treating rheumatic diseases that the present embodiment 5 makes one month's treatment , joint swelling and pain gradually disappeared, functional recovery, self-care, follow-up investigation, drug withdrawal 2 years without recurrence.

病例2:郭某,女,63岁,教师,患类风湿关节炎5年之久,长期服用激素药及止痛药,病情日渐加重,且出现全身及面部浮肿,全身关节肿痛,双手骨关节畸形,双肘,膝关节强直,生活完全失理,服用本实施例5制得的治疗风湿类病症的消炎止痛复方中药组合物汤剂E六个月,关节肿痛基本消失,功能改善,可从事正常工作,停药后随访,至今未复发。Case 2: Guo, female, 63 years old, a teacher, has suffered from rheumatoid arthritis for 5 years. She has been taking hormone drugs and painkillers for a long time. Deformity, both elbows, ankylosis of the knee joints, and life is completely unreasonable. After taking the anti-inflammatory and analgesic compound Chinese medicine composition decoction E for the treatment of rheumatic diseases prepared in this embodiment 5 for six months, the joint swelling and pain basically disappeared, and the function improved. Engaged in normal work, follow-up after drug withdrawal, no recurrence so far.

病例3:张某,男,65岁,农民,因外伤而出现膝关节疼痛,关节红肿,经医院化验诊断为类风湿性关节炎,常服用消炎痛、强的松等药物疗效欠佳,服用本实施例5制得的治疗风湿类病症的消炎止痛复方中药组合物汤剂E一个月双下肢由冷变温,精神良好,随访现能下地干活。Case 3: Zhang, male, 65 years old, a farmer, suffered knee joint pain and joint swelling due to trauma, and was diagnosed as rheumatoid arthritis by hospital tests. The anti-inflammatory and analgesic compound Chinese medicine composition decoction E prepared in Example 5 for the treatment of rheumatic diseases changed from cold to warm in one month, and he was in good spirits, and he was able to work in the field after follow-up.

病例4:徐某,女,42岁,工人,经医院诊断为患风湿类风湿关节炎,肢关节肿痛,僵硬,双手指变形,无法合拢,手指无法正常工作,服用本实施例5制得的治疗风湿类病症的消炎止痛复方中药组合物汤剂E,经过两个月的治疗,症状明显减轻,手指可以像正常人一样完全合拢,并且能参加工作,跟踪随访,无复发。Case 4: Xu, female, 42 years old, worker, was diagnosed as suffering from rheumatic rheumatoid arthritis through the hospital, extremity and joint swelling and pain, stiffness, both fingers deformed, unable to close, and fingers could not work normally. After two months of treatment, the anti-inflammatory and analgesic compound Chinese medicine composition decoction E for treating rheumatic diseases, the symptoms were significantly relieved, the fingers could be completely closed like normal people, and they could participate in work, and there was no recurrence during follow-up.

上述实施方式旨在举例说明本发明可为本领域专业技术人员实现或使用,对上述实施方式进行修改对本领域的专业技术人员来说将是显而易见的,故本发明包括但不限于上述实施方式,任何符合本权利要求书或说明书描述,符合与本文所公开的原理和新颖性、创造性特点的方法、工艺、产品,均落入本发明的保护范围之内。The above embodiments are intended to illustrate that the present invention can be implemented or used by those skilled in the art. It will be obvious to those skilled in the art to modify the above embodiments, so the present invention includes but is not limited to the above embodiments. Any method, process, or product that conforms to the claims or the description of the specification, and conforms to the principles, novelty, and creative features disclosed herein falls within the protection scope of the present invention.

Claims (9)

1.一种治疗风湿类病症的消炎止痛复方中药组合物,其特征是:由以下组分按照所示重量份比例范围配制,防风5~15份、秦艽7~17份、寻骨风10~20份、追地风10~20份、当归10~20份、赤芍7~17份、茯苓15~25份、羌活10~20份、独活7~17份、桂枝7~17份、威灵仙12~18份、黄芪19~29份、银花25~35份、甘草3~8份。1. An anti-inflammatory and analgesic compound traditional Chinese medicine composition for treating rheumatic diseases, characterized in that: it is prepared from the following components according to the proportions shown in parts by weight: 5-15 parts of Fangfeng, 7-17 parts of Gentiana chinensis, 10-10 parts of Xugufeng 20 parts, 10-20 parts of chasing ground wind, 10-20 parts of angelica, 7-17 parts of red peony root, 15-25 parts of Poria cocos, 10-20 parts of notopterygium, 7-17 parts of duhuo, 7-17 parts of cassia twig, Lingxian 12-18 parts, Astragalus 19-29 parts, Silver Flower 25-35 parts, Licorice 3-8 parts. 2.根据权利要求1所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例范围配制,防风9~11份、秦艽11~13份、寻骨风14~16份、追地风14~16份、当归14~16份、赤芍11~13份、茯苓19~21份、羌活14~16份、独活11~13份、桂枝11~13份、威灵仙14~16份、黄芪23~25份、银花29~31份、甘草5~7份。2. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 1, characterized in that: said Chinese medicine composition is prepared from the following components according to the proportions shown in parts by weight, 9-11 parts of Fangfeng, Gentiana 11-13 parts, Xun Gu Feng 14-16 parts, Zhui Di Feng 14-16 parts, Angelica 14-16 parts, Radix Paeoniae Rubra 11-13 parts, Poria cocos 19-21 parts, Notopterygium 14-16 parts, Du Huo 11-13 parts 11-13 parts of Guizhi, 14-16 parts of Clematis, 23-25 parts of Astragalus, 29-31 parts of Silver Flower, and 5-7 parts of Licorice. 3.根据权利要求1所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例配制,防风15份、秦艽7份、寻骨风20份、追地风10份、当归20份、赤芍7份、茯苓25份、羌活10份、独活17份、桂枝7份、威灵仙18份、黄芪19份、银花35份、甘草3份。3. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 1, characterized in that: said Chinese medicine composition is prepared according to the proportions by weight of the following components, 15 parts of Fangfeng, 7 parts of Gentiana, 20 parts of Xugufeng, 10 parts of Zhuifeng, 20 parts of Angelica, 7 parts of Radix Paeoniae Rubra, 25 parts of Poria cocos, 10 parts of Qianghuo, 17 parts of Duhuo, 7 parts of Guizhi, 18 parts of Clematis, 19 parts of Astragalus, Yinhua 35 parts, 3 parts of licorice. 4.根据权利要求1所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例配制,中药组合物由以下组分按照所示重量份比例范围配制,防风5份、秦艽17份、寻骨风10份、追地风20份、当归10份、赤芍17份、茯苓15份、羌活20份、独活7份、桂枝17份、威灵仙12份、黄芪29份、银花25份、甘草8份。4. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 1, characterized in that: said Chinese medicine composition is prepared from the following components according to the proportions shown in parts by weight, and the Chinese medicine composition is prepared from the following components according to The ratio range of weight parts shown is prepared, Fangfeng 5 parts, Gentiana 17 parts, Xugufeng 10 parts, Zhuidifeng 20 parts, Angelica 10 parts, Radix Paeoniae Rubra 17 parts, Poria cocos 15 parts, Notopterygium 20 parts, Duhuo 7 parts, Gui Branch 17, Clematis 12, Astragalus 29, Silver Flower 25, Licorice 8. 5.根据权利要求2所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例配制,防风11份、秦艽11份、寻骨风16份、追地风14份、当归16份、赤芍11份、茯苓19份、羌活14份、独活13份、桂枝11份、威灵仙14份、黄芪23份、银花31份、甘草5份。5. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 2, characterized in that: said Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 11 parts of Fangfeng, 11 parts of Gentiana, Xugufeng 16 parts, Zhui Difeng 14 parts, Angelica 16 parts, Radix Paeoniae Rubra 11 parts, Poria cocos 19 parts, Notopterygium 14 parts, Duhuo 13 parts, Guizhi 11 parts, Clematis 14 parts, Astragalus 23 parts, Silver Flower 31 parts, 5 parts of licorice. 6.根据权利要求2所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例配制,防风9份、秦艽13份、寻骨风14份、追地风16份、当归14份、赤芍13份、茯苓21份、羌活16份、独活11份、桂枝13份、威灵仙16份、黄芪25份、银花29份、甘草7份。6. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 2, characterized in that: said Chinese medicine composition is prepared from the following components according to the proportions by weight shown, 9 parts of Fangfeng, 13 parts of Gentiana, Xugufeng 14 parts, Zhui Difeng 16 parts, Angelica 14 parts, Radix Paeoniae Rubra 13 parts, Poria cocos 21 parts, Notopterygium 16 parts, Duhuo 11 parts, Guizhi 13 parts, Clematis 16 parts, Astragalus 25 parts, Silver Flower 29 parts, 7 parts of licorice. 7.根据权利要求2所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物由以下组分按照所示重量份比例配制,防风10份、秦艽12份、寻骨风15份、追地风15份、当归15份、赤芍12份、茯苓20份、羌活15份、独活12份、桂枝12份、威灵仙15份、黄芪24份、银花30份、甘草6份。7. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 2, characterized in that: said Chinese medicine composition is prepared from the following components according to the proportions shown in parts by weight, 10 parts of Fangfeng, 12 parts of Gentiana, Xugufeng 15 parts, Zhui Difeng 15 parts, Angelica 15 parts, Radix Paeoniae Rubra 12 parts, Poria cocos 20 parts, Notopterygium 15 parts, Duhuo 12 parts, Guizhi 12 parts, Clematis 15 parts, Astragalus 24 parts, Silver Flower 30 parts, 6 parts of licorice. 8.根据权利要求2所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物每付配方为,防风10g、秦艽12g、寻骨风15g、追地风15g、当归15g、赤芍12g、茯苓20g、羌活15g、独活12g、桂枝12g、威灵仙15g、黄芪24g、银花30g、甘草6g。8. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 2, characterized in that: each formula of the Chinese medicine composition is Fangfeng 10g, Gentiana chinensis 12g, Xugufeng 15g, Zuidifeng 15g , Angelica 15g, Radix Paeoniae Rubra 12g, Poria 20g, Notopterygium 15g, Duhuo 12g, Guizhi 12g, Clematis 15g, Astragalus 24g, Silver Flower 30g, Licorice 6g. 9.根据权利要求1所述的治疗风湿类病症的消炎止痛复方中药组合物,其特征是:所述中药组合物剂型为汤剂,其制备方法为,按权利要求1至8任一所述的重量份比例或配方量取各组分,将各组分粉碎研磨后过100~200目筛,得混合粉末,向该混合粉末中加醋炒干,再加水煎制3~5h,过滤取药汤,即得本治疗风湿类病症的消炎止痛复方中药组合物汤剂。9. The anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases according to claim 1, characterized in that: the dosage form of the Chinese medicine composition is a decoction, and its preparation method is as described in any one of claims 1 to 8. The weight ratio or formula measures each component, crushes and grinds each component and passes through a 100-200 mesh sieve to obtain a mixed powder. Add vinegar to the mixed powder and fry it dry, add water and decoct it for 3-5 hours, filter and take Medicinal decoction, that is, the decoction of the anti-inflammatory and analgesic compound Chinese medicine composition for treating rheumatic diseases.
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CN103735756A (en) * 2014-01-10 2014-04-23 张其波 Traditional Chinese medicinal prescription for treating low back and leg pain
CN104127588A (en) * 2014-08-19 2014-11-05 太仓优活生物技术有限公司 Chinese herbal medicine capable of reliving pain
CN105213968A (en) * 2015-10-08 2016-01-06 山东健科生物技术有限公司 A kind of foot bath preparation being used for the treatment of hysteromyoma and preparation method thereof

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CN101530566A (en) * 2008-03-10 2009-09-16 王林祥 Drug for treating rheumatism and rheumatoid disease
CN102961438A (en) * 2012-11-14 2013-03-13 无锡力盟生物科技有限公司 Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and preparation method thereof

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WO2003059370A1 (en) * 2002-01-18 2003-07-24 Pangenomics Co., Ltd. Crude drug compositions for treating or preventing arthritic diseases and the preparation process
CA2569836A1 (en) * 2004-06-09 2005-12-22 Shenzhen Qianrenren Sci. & Tech. Development Co., Ltd. Herbal compositions for prevention and treatment of rheumatic and inflammatory diseases and method of preparing the same
CN101530566A (en) * 2008-03-10 2009-09-16 王林祥 Drug for treating rheumatism and rheumatoid disease
CN101401846A (en) * 2008-11-09 2009-04-08 刘爱玲 Bi-syndrome treating Chinese medicine preparation
CN102961438A (en) * 2012-11-14 2013-03-13 无锡力盟生物科技有限公司 Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103735756A (en) * 2014-01-10 2014-04-23 张其波 Traditional Chinese medicinal prescription for treating low back and leg pain
CN104127588A (en) * 2014-08-19 2014-11-05 太仓优活生物技术有限公司 Chinese herbal medicine capable of reliving pain
CN105213968A (en) * 2015-10-08 2016-01-06 山东健科生物技术有限公司 A kind of foot bath preparation being used for the treatment of hysteromyoma and preparation method thereof

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