CN102935080A - 苯达莫司汀环多糖组合物 - Google Patents

苯达莫司汀环多糖组合物 Download PDF

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Publication number
CN102935080A
CN102935080A CN2012104076231A CN201210407623A CN102935080A CN 102935080 A CN102935080 A CN 102935080A CN 2012104076231 A CN2012104076231 A CN 2012104076231A CN 201210407623 A CN201210407623 A CN 201210407623A CN 102935080 A CN102935080 A CN 102935080A
Authority
CN
China
Prior art keywords
bendamustine
composition
cyclodextrin
sbecd
charged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012104076231A
Other languages
English (en)
Chinese (zh)
Inventor
T·波佩克
K·帕特勒
V·艾拉霍夫
G·皮奇纳斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sofitel Kaimo Pharmaceutical Co
Original Assignee
Supratek Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42631521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102935080(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Supratek Pharma Inc filed Critical Supratek Pharma Inc
Publication of CN102935080A publication Critical patent/CN102935080A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2012104076231A 2009-02-25 2010-02-24 苯达莫司汀环多糖组合物 Pending CN102935080A (zh)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US20854109P 2009-02-25 2009-02-25
US61/208,541 2009-02-25
US26994409P 2009-07-01 2009-07-01
US61/269,944 2009-07-01
US27136409P 2009-07-20 2009-07-20
US61/271,364 2009-07-20
US27929309P 2009-10-19 2009-10-19
US61/279,293 2009-10-19
US12/711,979 2010-02-24
US12/711,979 US8436032B2 (en) 2009-02-25 2010-02-24 Bendamustine cyclopolysaccharide compositions

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2010800183017A Division CN102421451B (zh) 2009-02-25 2010-02-24 苯达莫司汀环多糖组合物

Publications (1)

Publication Number Publication Date
CN102935080A true CN102935080A (zh) 2013-02-20

Family

ID=42631521

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2012104076231A Pending CN102935080A (zh) 2009-02-25 2010-02-24 苯达莫司汀环多糖组合物
CN2010800183017A Active CN102421451B (zh) 2009-02-25 2010-02-24 苯达莫司汀环多糖组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2010800183017A Active CN102421451B (zh) 2009-02-25 2010-02-24 苯达莫司汀环多糖组合物

Country Status (12)

Country Link
US (2) US8436032B2 (https=)
EP (2) EP2792369B1 (https=)
JP (1) JP5654498B2 (https=)
KR (1) KR101798951B1 (https=)
CN (2) CN102935080A (https=)
AU (1) AU2010217297A1 (https=)
CA (1) CA2753641C (https=)
ES (2) ES2525257T3 (https=)
HU (1) HUE038234T2 (https=)
NO (1) NO2792369T3 (https=)
RU (2) RU2591804C2 (https=)
WO (1) WO2010097700A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021203377A1 (zh) * 2020-04-09 2021-10-14 比卡生物科技（广州）有限公司 苯达莫司汀组合物及其用途

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WO2010097700A1 (en) 2009-02-25 2010-09-02 Supratek Pharma, Inc. Bendamustine cyclopolysaccharide compositions
PL3158991T3 (pl) 2010-01-28 2021-09-27 Eagle Pharmaceuticals, Inc. Preparaty bendamustyny
WO2011103150A2 (en) * 2010-02-18 2011-08-25 Cephalon, Inc. Lyophilized preparations of bendamustine
US20110207764A1 (en) * 2010-02-23 2011-08-25 Valery Alakhov Cyclopolysaccharide compositions
US8383663B2 (en) 2010-07-19 2013-02-26 Supratek Pharma Inc. Bendamustine anionic-catioinic cyclopolysaccharide compositions
WO2013040286A2 (en) 2011-09-18 2013-03-21 Euro-Celtique S.A. Pharmaceutical compositions
AR092790A1 (es) 2012-02-01 2015-05-06 Euro Celtique Sa Derivados bencimidazolicos del acido hidroxamico
PL2827863T3 (pl) 2012-03-20 2019-07-31 Eagle Pharmaceuticals, Inc. Ciekła kompozycja do zastosowania w sposobie leczenia stanów reagujących na bendamustynę u pacjentów wymagających obniżonych objętości do podawania
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
CA2867295C (en) 2012-03-20 2020-08-11 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
DK2925327T3 (da) * 2012-11-30 2024-03-25 Univ California Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression
ES2957541T3 (es) * 2013-08-27 2024-01-22 Vasilios Voudouris Composiciones farmacéuticas de bendamustina
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409488D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
AU2016426574B2 (en) 2016-10-11 2023-07-13 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
SG11202003098WA (en) 2017-10-05 2020-05-28 Tube Pharmaceuticals Gmbh Oral bendamustine formulations
US11730815B2 (en) * 2018-11-26 2023-08-22 Good Health, Llc Stable liquid pharmaceutical compositions comprising bendamustine
CN113365624A (zh) 2018-12-18 2021-09-07 萌蒂制药国际有限公司 用于治疗淋巴瘤或t-细胞恶性疾病的化合物
CN111557904A (zh) * 2020-04-09 2020-08-21 比卡生物科技（广州）有限公司 苯达莫司汀组合物及其用途
US20240148696A1 (en) 2022-10-25 2024-05-09 Softkemo Pharma Inc. Lyophilized bendamustine-cyclodextrin composition

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021203377A1 (zh) * 2020-04-09 2021-10-14 比卡生物科技（广州）有限公司 苯达莫司汀组合物及其用途

Also Published As

Publication number Publication date
EP2792369A1 (en) 2014-10-22
CA2753641C (en) 2014-09-16
RU2016124871A (ru) 2018-12-04
ES2675620T3 (es) 2018-07-11
EP2792369B1 (en) 2018-04-18
JP5654498B2 (ja) 2015-01-14
ES2525257T3 (es) 2014-12-19
CA2753641A1 (en) 2010-09-02
KR20120015294A (ko) 2012-02-21
EP2400987A4 (en) 2012-08-22
CN102421451B (zh) 2013-11-06
RU2591804C2 (ru) 2016-07-20
US8436032B2 (en) 2013-05-07
WO2010097700A1 (en) 2010-09-02
US8703964B2 (en) 2014-04-22
KR101798951B1 (ko) 2017-11-20
US20130190372A1 (en) 2013-07-25
US20100216858A1 (en) 2010-08-26
EP2400987A1 (en) 2012-01-04
RU2016124871A3 (https=) 2019-11-11
NO2792369T3 (https=) 2018-09-15
CN102421451A (zh) 2012-04-18
HUE038234T2 (hu) 2018-10-29
RU2011138844A (ru) 2013-04-10
EP2400987B1 (en) 2014-09-03
RU2734236C2 (ru) 2020-10-13
AU2010217297A1 (en) 2011-10-20
JP2012519657A (ja) 2012-08-30

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20170705

Address after: Quebec

Applicant after: Sofitel Kaimo Pharmaceutical Co.

Address before: Quebec

Applicant before: Supratek Pharma Inc.

RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20130220