CN102928360B - 血液分析装置和血液分析方法 - Google Patents

血液分析装置和血液分析方法 Download PDF

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Publication number
CN102928360B
CN102928360B CN201210271673.1A CN201210271673A CN102928360B CN 102928360 B CN102928360 B CN 102928360B CN 201210271673 A CN201210271673 A CN 201210271673A CN 102928360 B CN102928360 B CN 102928360B
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spectrum
standard
red blood
measure
heme
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Chinese (zh)
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CN102928360A (zh
Inventor
松居惠理子
堂胁优
辰田宽和
国弘威
丹羽明
斋藤润
中畑龙俊
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Sony Corp
Kyoto University NUC
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Sony Corp
Kyoto University NUC
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3144Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths for oxymetry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3155Measuring in two spectral ranges, e.g. UV and visible

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201210271673.1A 2011-08-08 2012-08-01 血液分析装置和血液分析方法 Expired - Fee Related CN102928360B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011-172736 2011-08-08
JP2011172736A JP5959814B2 (ja) 2011-08-08 2011-08-08 血液分析装置および血液分析方法

Publications (2)

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CN102928360A CN102928360A (zh) 2013-02-13
CN102928360B true CN102928360B (zh) 2017-06-20

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US (1) US8736824B2 (https=)
EP (1) EP2557413B1 (https=)
JP (1) JP5959814B2 (https=)
CN (1) CN102928360B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
US10640807B2 (en) 2011-12-29 2020-05-05 S.D. Sight Diagnostics Ltd Methods and systems for detecting a pathogen in a biological sample
EP2999988A4 (en) 2013-05-23 2017-01-11 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
WO2015029032A1 (en) 2013-08-26 2015-03-05 Parasight Ltd. Digital microscopy systems, methods and computer program products
ES2856261T3 (es) * 2013-10-01 2021-09-27 Fresenius Medical Care Deutschland Gmbh Método y aparatos para determinar una pérdida diaria de hierro de un paciente
JP6284145B2 (ja) * 2014-02-17 2018-02-28 国立研究開発法人産業技術総合研究所 血栓や血液の凝固の形成その成長を観察する装置
US10482595B2 (en) 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
KR102345905B1 (ko) 2015-07-30 2021-12-30 삼성전자주식회사 분광기의 반복 재현성 검증 장치 및 방법, 스펙트럼 데이터 분석 장치
US10488644B2 (en) 2015-09-17 2019-11-26 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
CA3018536A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinguishing between blood sample components
WO2017195205A1 (en) 2016-05-11 2017-11-16 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
EP3455626B1 (en) 2016-05-11 2025-08-06 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
EP3296720A1 (de) * 2016-09-14 2018-03-21 Siemens Healthcare Diagnostics Products GmbH Verfahren und system zur zuordnung einer körperflüssigkeitsprobe zu einer körperflüssigkeitsprobenklasse
IT201600103909A1 (it) * 2016-10-17 2018-04-17 Marco Flavio Michele Vismara Sistema e metodo di acquisizione, trasmissione ed elaborazione di dati ematochimici
CN111788471B (zh) 2017-11-14 2023-12-12 思迪赛特诊断有限公司 用于光学测量的样品载体
JP7257182B2 (ja) * 2019-02-27 2023-04-13 京セラ株式会社 検査装置および検査方法
CN110648755A (zh) * 2019-09-10 2020-01-03 云南博亚医院有限公司 一种血液透析质量评估及管理系统
AU2020370212B2 (en) 2019-10-22 2025-09-25 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
CN114787625B (zh) 2019-12-12 2026-01-13 思迪赛特诊断有限公司 检测血液样品中的血小板
JP7677972B2 (ja) 2019-12-12 2025-05-15 エス.ディー.サイト ダイアグノスティックス リミテッド カラー血液スミア画像の人工的な生成
BR112022011312A2 (pt) 2019-12-12 2022-08-23 S D Sight Diagnostics Ltd Análise de um analito disposto dentro de um meio
CN111110175B (zh) * 2019-12-31 2023-04-07 深圳开立生物医疗科技股份有限公司 一种内窥镜光源及其调光方法、装置和内窥镜系统
JP7292434B2 (ja) * 2020-01-21 2023-06-16 株式会社エビデント 赤血球分化モニタリング装置および赤血球分化モニタリング方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1769892A (zh) * 2005-09-30 2006-05-10 中国人民解放军军事医学科学院野战输血研究所 一种监测血液保质期的方法
CN101876629A (zh) * 2008-12-19 2010-11-03 霍夫曼-拉罗奇有限公司 用于确定血样溶血的方法和装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376828A (en) * 1981-08-20 1983-03-15 Miles Laboratories, Inc. Bilirubin test kit
US5589932A (en) 1995-02-08 1996-12-31 University Of South Florida Spectrophotometric method and apparatus for the characterization of blood and blood types
JPH09281101A (ja) * 1996-04-18 1997-10-31 Matsushita Electric Ind Co Ltd 検尿装置とこれを用いた排泄機器
US7157282B2 (en) 1996-06-12 2007-01-02 Spectromedical Inc. Quality control material for reagentless measurement of analytes
US6662031B1 (en) * 1998-05-18 2003-12-09 Abbott Laboratoies Method and device for the noninvasive determination of hemoglobin and hematocrit
CA2245422A1 (en) * 1998-07-14 2000-01-14 Ortho-Clinical Diagnostics, Inc. Improved analyzer throughput featuring through-the-tip analysis
JP2003508144A (ja) 1999-09-08 2003-03-04 オプトク・アクチボラゲット ヘモグロビン及び酸素飽和度を複合測定するための方法及び装置
US7449339B2 (en) * 1999-11-23 2008-11-11 Nir Diagnostics Inc. Spectroscopic method and apparatus for total hemoglobin measurement
US20050037505A1 (en) * 2000-05-11 2005-02-17 James Samsoondar Spectroscopic method and apparatus for analyte measurement
US7109038B2 (en) * 2002-06-13 2006-09-19 The Johns Hopkins University Occult blood detection in biological samples by laser desorption and matrix-assisted laser desorption/ionization mass spectrometry for biomedical applications
JP3868379B2 (ja) * 2003-02-20 2007-01-17 独立行政法人科学技術振興機構 交互吸着膜を利用したビリルビンセンサー
CA2460898A1 (en) 2004-03-09 2005-09-09 James Samsoondar Apparatus and method for combining in vivo and in vitro testing
JP2005333978A (ja) * 2004-04-27 2005-12-08 Asahi Kasei Pharma Kk ビリルビン測定方法
EP2645086A3 (en) 2006-03-16 2014-03-12 Sysmex Corporation Sample analyzer
SE533103C2 (sv) * 2008-04-01 2010-06-29 Tommy Forsell Blodviskositetsanalys
GB2461246A (en) * 2008-04-21 2009-12-30 Amc Amsterdam Dating a sample of a body fluid using optical spectroscopy
JP2011172736A (ja) 2010-02-24 2011-09-08 Univ Of Tokyo 貼着装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1769892A (zh) * 2005-09-30 2006-05-10 中国人民解放军军事医学科学院野战输血研究所 一种监测血液保质期的方法
CN101876629A (zh) * 2008-12-19 2010-11-03 霍夫曼-拉罗奇有限公司 用于确定血样溶血的方法和装置

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JP2013036832A (ja) 2013-02-21
EP2557413B1 (en) 2019-10-02
EP2557413A3 (en) 2013-05-29
US8736824B2 (en) 2014-05-27
JP5959814B2 (ja) 2016-08-02
EP2557413A2 (en) 2013-02-13
CN102928360A (zh) 2013-02-13
US20130038860A1 (en) 2013-02-14

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