CN102919540A - Fermented astragalus mongholicus feed additive and application thereof - Google Patents
Fermented astragalus mongholicus feed additive and application thereof Download PDFInfo
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- CN102919540A CN102919540A CN2012104499306A CN201210449930A CN102919540A CN 102919540 A CN102919540 A CN 102919540A CN 2012104499306 A CN2012104499306 A CN 2012104499306A CN 201210449930 A CN201210449930 A CN 201210449930A CN 102919540 A CN102919540 A CN 102919540A
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- radix astragali
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Abstract
The fermented astragalus mongholicus feed additive and application thereof relates to feed additive and application of the feed additive which is added into piglet feed to feed weaned pigs. Lactobacillus acidophilus powder and streptococcus faecium powder are mixed according to the mass ration of 1-2 to 6-8. On anaerobic condition, astragalus mongholicus powder is fermented to enable astragalus mongholicus polysaccharide to be released in maximum. A fermentation process is that fermentation medium comprises astragalus mongholicus and 1% to 3% of cane sugar, the fermentation process comprises 0.2% to 0.4% of inoculum size and 30% to 40% of water, fermentation time is 5 to 7 days, and temperature is between 35 DEG C to 38 DEG C. The modern fermentation technology is utilized to ferment astragalus mongholicus, and he astragalus mongholicus polysaccharide content is 19.78% to 24.12%. Compared with original astragalus mongholicus powder, the astragalus mongholicus polysaccharide content is incrased by 467% to 591%. The fermented astragalus mongholicus feed additive has the functions of increasing piglet food consumption, improving daily gain of the piglets, improving feed utilization rate, improving piglet diarrhea and improving piglet immunity.
Description
Technical field
The present invention relates to a kind of feed addictive joint and use, be specifically related to a kind of Radix Astragali feed addictive and add the application of feeding weanling pig in the pig starter feed as feed addictive to of fermenting.
Background technology
The Chinese medicine Radix Astragali is leguminous herbaceous plant, has the effects such as invigorating qi for strengthening superficies, sharp water detumescence, pus draining and toxin expelling, myogenic.Medicinal existing more than the 2000 year history of the Radix Astragali, modern study shows, contains the various trace elements such as polysaccharide, saponin, several amino acids, sucrose, folic acid and selenium, zinc, copper in the Radix Astragali.
Astragalus polyose is one of active ingredient of the Radix Astragali, has immunoregulation effect, and it can improve the immune response ability of antigen and lymphocytic conversion ratio, and can strengthen the phagocytic activity of macrophage; To the early weaning of weanling pig stress, have obvious immunological enhancement.Add astragalus polyose and can improve the daily gain of weanling pig, reduce diarrhea rate, also improved the digestibility of weanling pig to nutriment simultaneously.But, the method for the existing processing Radix Astragali, the recovery rate of astragalus polyose is relatively low, becomes the major technique bottleneck that limits its application.Therefore, how to make the Radix Astragali produce in a large number astragalus polyose and just become the urgent problem that solves of pig industry.
Early-weaned piglets stress be one of several large problems of restriction pig industry development, at present, in existing feed addictive, the stress of baby pigs caused ablaction best results be antibiotic, antibiotic not only can be alleviated the ablactation stress of piglet, also can improve to a certain extent the daily gain of piglet.But because the antibiotic problem such as residual, with disabled.Astragalus polyose as the active ingredient of the Radix Astragali, played obvious effect at control grice diarrhoea and raising weaned piglets, and the fermentation Radix Astragali can make a large amount of release of astragalus polyose.
Summary of the invention
The purpose of this invention is to provide a kind of fermentation Radix Astragali feed addictive and application thereof, utilize modern fermentation technique that the Radix Astragali is fermented, improve the content of astragalus polyose.
The objective of the invention is to be achieved through the following technical solutions:
The present invention mixes with the mass ratio of two kinds of industrial bacterium powder (lactobacillus acidophilus bacterium powder and streptococcus fecalis bacterium powder) with 1 ~ 2:6 ~ 8, and the astragalus membranaceus powder of 60 ~ 120 mesh sieves that under anaerobic fermented discharges the astragalus polyose maximum, and zymotechnique is as follows:
Fermentation medium: the Radix Astragali, sucrose 1 ~ 3%.
Zymotechnique: inoculum concentration: 0.2 ~ 0.4%, water: 30 ~ 40%, fermentation time: 5 ~ 7 days; Temperature: 35 ~ 38 ℃.
Oxygen free condition can suppress the growth of other bacteriums effectively, can avoid lactic acid bacteria to be polluted.The sucrose that adds in the fermentation medium is raw material cheap and easy to get, is convenient to actual application.
Use: the Radix Astragali that will ferment adds the weanling pig of feeding in the pig starter feed as feed addictive to 0.10 ~ 0.50% addition, thereby reaches the effect of raising weaned piglets and autoimmunity.
The present invention utilizes modern fermentation technique that the Radix Astragali is fermented, and the astragalus polyose content of fermentation formulation of astragalus root is 19.78 ~ 24.12%, compares with the former powder of the Radix Astragali, has increased by 467 ~ 591%.The effect that fermentation formulation of astragalus root of the present invention has to be increased the piglet feed intake, improve the piglet daily gain, improve efficiency of feed utilization, improve grice diarrhoea and improve pigling immunity.
The specific embodiment
Below in conjunction with embodiment the technical solution of the present invention is further explained explanation.
The experimental design of adopting single factor experiment and orthogonal test to combine is optimized factor inoculum concentration, water content, the fermentation time of impact fermentation take final astragalus polyose burst size as standard.Wherein the level of inoculum concentration design is 0.2%, 0.4%, 1.0%, 1.5%, 2.0%, 3.0% in the single factor experiment, and the level of water content design is 20%, 30%, 40%, 50%, 60%, 70%, and the level of fermentation time design is 3d, 5d, 7d, 9d; Orthogonal is the experimental design of Three factors-levels.Every group of test all designs 3 repetitions.The optimal conditions of fermentation of determining the Radix Isatidis powder is: water content is 35%, and inoculum concentration is 0.2%, and fermentation time is 6d, and concrete fermentation step is as follows:
The fermented and cultured that is comprised of the Radix Astragali, 2% sucrose that 20 g are prepared places 30min under the uviol lamp based in the plastic packaging bag, and is for subsequent use.Lactobacillus acidophilus bacterium powder is mixed with the ratio of 2:8 with streptococcus fecalis bacterium powder, according to 0.2%(V/m) inoculum concentration under anaerobic access respectively in the fermentation medium, water content is 35%, with vacuum packing machine the plastic packaging bag is vacuumized plastic packaging, fermentation time is 6 days, is constant temperature culture under 37 ℃ the condition in temperature.60 ℃ of oven dry, measuring Polysaccharide from Scutellaria Baicalensis content is 23.23%, compares with the former powder of the Radix Astragali, has increased by 509% after the fermentation.
Add the above-mentioned fermentation Radix Astragali to the weanling pig of feeding in the pig starter feed as feed addictive with 0.25% addition, wherein:
The average daily ingestion amount 519g of control group piglet, average daily gain 244g, feedstuff-meat ratio 2.12, diarrhea rate 0.18%;
The average daily ingestion amount 555g of the former powder group of the Radix Astragali, average daily gain 290g, feedstuff-meat ratio 1.91, diarrhea rate 0.12%;
The average daily ingestion amount 563g of fermentation Radix Astragali group, average daily gain 309g, feedstuff-meat ratio 1.82, diarrhea rate 0.05%.
This shows that the fermentation formulation of astragalus root is best to the action effect that improves piglet daily gain, raising efficiency of feed utilization and reduction diarrhea rate.
Immunoglobulin content in the control group piglet blood (ug/ml): IgA 28.60, and IgM 14.99, and IgG 179.30;
Immunoglobulin content (ug/ml) in the former powder group of the Radix Astragali blood: IgA 26.98, and IgM 15.23, and IgG 168.37;
Immunoglobulin content (ug/ml) in the fermentation Radix Astragali group blood: IgA 31.46, and IgM 15.48, and IgG 248.13.
Immune factor content (pg/ml) in the control group piglet blood: IL-2 114.57, and IL-4 115.60, TNF-α 81.99;
Immune factor content (pg/ml) in the former powder group of the Radix Astragali blood: IL-2 107.39, and IL-4 112.70, TNF-α 79.96;
Immune factor content (pg/ml) in the fermentation Radix Astragali group blood: IL-2 112.14, and IL-4 151.28, TNF-α 77.91;
This shows that the fermentation formulation of astragalus root has the effect that increases main immunoglobulin and partial immunity cytokine content in the weanling pig blood, thereby has strengthened the resistance against diseases of weanling pig.
Claims (6)
1. fermentation Radix Astragali feed addictive is characterized in that the described fermentation Radix Astragali ferments in accordance with the following steps to form: lactobacillus acidophilus bacterium powder mixed with the mass ratio of streptococcus fecalis bacterium powder with 1 ~ 2:6 ~ 8, and the astragalus membranaceus powder that under anaerobic ferments, zymotechnique is as follows:
Fermentation medium: the Radix Astragali, sucrose 1 ~ 3%;
Zymotechnique: inoculum concentration: 0.2 ~ 0.4%, water: 30 ~ 40%, fermentation time: 5 ~ 7 days; Temperature: 35 ~ 38 ℃.
2. fermentation Radix Astragali feed addictive according to claim 1 is characterized in that described astragalus membranaceus powder crosses 60 ~ 120 mesh sieves.
3. fermentation Radix Astragali feed addictive according to claim 1 is characterized in that described zymotechnique is as follows:
Fermentation medium: the Radix Astragali, sucrose 2%;
Zymotechnique: inoculum concentration: 0.2%, water: 35%, fermentation time: 6 days, temperature: 37 ℃.
4. the described fermentation Radix Astragali of claim 1 feed addictive adds the application of feeding weanling pig in the pig starter feed to as feed addictive.
5. the application of fermentation Radix Astragali feed addictive according to claim 4 is characterized in that described addition is 0.10-0.50%.
6. the application of fermentation Radix Astragali feed addictive according to claim 4 is characterized in that described addition is 0.25%.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104770575A (en) * | 2015-04-17 | 2015-07-15 | 河南牧业经济学院 | Astragalus membranaceus micro-ecologic preparation as well as preparation method and application thereof |
| CN104872396A (en) * | 2015-06-18 | 2015-09-02 | 湖北工业大学 | Method for preparing feed raw material by using corn steep liquor as substrate and fermenting astragalus membranaceus with lactobacillus rhamnosus |
| CN104886350A (en) * | 2015-06-08 | 2015-09-09 | 河南惠通天下生物工程有限公司 | Chinese herbal medicine microorganism fermentation preparation, as well as preparation method and using method thereof |
| CN106173212A (en) * | 2016-06-28 | 2016-12-07 | 淮北普成饲料有限公司 | A kind of concentrated feed additive agent and preparation technology thereof |
| CN110122691A (en) * | 2019-05-28 | 2019-08-16 | 常熟市金牧药业有限公司 | Composite premixed feed for pigs |
| CN115316566A (en) * | 2022-08-30 | 2022-11-11 | 中国水产科学研究院黑龙江水产研究所 | Additive for carp feed and use method of additive |
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| CN101116473A (en) * | 2006-08-01 | 2008-02-06 | 济南亿民动物药业有限公司 | Method for preparing glycolysis Chinese herbal medicine preparations for feed |
| CN101683124A (en) * | 2008-09-28 | 2010-03-31 | 天津生机集团股份有限公司 | Method for producing poultry and livestock feed additive by fermentation of astragalus root dregs |
| CN102232998A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Micro-ecological traditional Chinese medicine preparation for enhancing immunity of livestock and poultry, and preparation method thereof |
| CN102356822A (en) * | 2011-09-28 | 2012-02-22 | 蔡廷贵 | Fermented traditional Chinese medicine feed additive for pigs and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101116473A (en) * | 2006-08-01 | 2008-02-06 | 济南亿民动物药业有限公司 | Method for preparing glycolysis Chinese herbal medicine preparations for feed |
| CN101683124A (en) * | 2008-09-28 | 2010-03-31 | 天津生机集团股份有限公司 | Method for producing poultry and livestock feed additive by fermentation of astragalus root dregs |
| CN102232998A (en) * | 2011-04-15 | 2011-11-09 | 北京康华远景科技有限公司 | Micro-ecological traditional Chinese medicine preparation for enhancing immunity of livestock and poultry, and preparation method thereof |
| CN102356822A (en) * | 2011-09-28 | 2012-02-22 | 蔡廷贵 | Fermented traditional Chinese medicine feed additive for pigs and preparation method thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104770575A (en) * | 2015-04-17 | 2015-07-15 | 河南牧业经济学院 | Astragalus membranaceus micro-ecologic preparation as well as preparation method and application thereof |
| CN104770575B (en) * | 2015-04-17 | 2018-01-12 | 河南牧业经济学院 | A kind of Radix Astragali probiotics and its preparation method and application |
| CN104886350A (en) * | 2015-06-08 | 2015-09-09 | 河南惠通天下生物工程有限公司 | Chinese herbal medicine microorganism fermentation preparation, as well as preparation method and using method thereof |
| CN104872396A (en) * | 2015-06-18 | 2015-09-02 | 湖北工业大学 | Method for preparing feed raw material by using corn steep liquor as substrate and fermenting astragalus membranaceus with lactobacillus rhamnosus |
| CN106173212A (en) * | 2016-06-28 | 2016-12-07 | 淮北普成饲料有限公司 | A kind of concentrated feed additive agent and preparation technology thereof |
| CN110122691A (en) * | 2019-05-28 | 2019-08-16 | 常熟市金牧药业有限公司 | Composite premixed feed for pigs |
| CN115316566A (en) * | 2022-08-30 | 2022-11-11 | 中国水产科学研究院黑龙江水产研究所 | Additive for carp feed and use method of additive |
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Application publication date: 20130213 |