CN102905711A - 自体真皮成纤维细胞的剂量单位调配物 - Google Patents

自体真皮成纤维细胞的剂量单位调配物 Download PDF

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Publication number
CN102905711A
CN102905711A CN2011800230385A CN201180023038A CN102905711A CN 102905711 A CN102905711 A CN 102905711A CN 2011800230385 A CN2011800230385 A CN 2011800230385A CN 201180023038 A CN201180023038 A CN 201180023038A CN 102905711 A CN102905711 A CN 102905711A
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cell
cells
treatment
dose
fibroblast
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CN2011800230385A
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Chinese (zh)
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约翰·马斯洛斯基
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Fibrocell Technologies Inc
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Fibrocell Technologies Inc
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Priority to CN201710907274.2A priority Critical patent/CN107812014B/zh
Publication of CN102905711A publication Critical patent/CN102905711A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
CN2011800230385A 2010-05-07 2011-05-05 自体真皮成纤维细胞的剂量单位调配物 Pending CN102905711A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710907274.2A CN107812014B (zh) 2010-05-07 2011-05-05 自体真皮成纤维细胞的剂量单位调配物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/776,163 US8529883B2 (en) 2010-05-07 2010-05-07 Dosage unit formulations of autologous dermal fibroblasts
US12/776,163 2010-05-07
PCT/US2011/035332 WO2011140323A1 (en) 2010-05-07 2011-05-05 Dosage unit formulations of autologous dermal fibroblasts

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201710907274.2A Division CN107812014B (zh) 2010-05-07 2011-05-05 自体真皮成纤维细胞的剂量单位调配物

Publications (1)

Publication Number Publication Date
CN102905711A true CN102905711A (zh) 2013-01-30

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CN2011800230385A Pending CN102905711A (zh) 2010-05-07 2011-05-05 自体真皮成纤维细胞的剂量单位调配物
CN201710907274.2A Active CN107812014B (zh) 2010-05-07 2011-05-05 自体真皮成纤维细胞的剂量单位调配物

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Country Status (8)

Country Link
US (3) US8529883B2 (https=)
EP (1) EP2566489B1 (https=)
JP (1) JP6309268B2 (https=)
KR (1) KR102001254B1 (https=)
CN (2) CN102905711A (https=)
AU (1) AU2011248067B2 (https=)
CA (1) CA2800333C (https=)
WO (1) WO2011140323A1 (https=)

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WO2011075676A2 (en) 2009-12-18 2011-06-23 Knowlton Edward W A skin treatment and drug delivery device
US8529883B2 (en) * 2010-05-07 2013-09-10 Fibrocell Technologies, Inc. Dosage unit formulations of autologous dermal fibroblasts
US8765121B2 (en) * 2010-10-14 2014-07-01 Fibrocell Technologies, Inc. Treatment of vocal cords with autologous dermal fibroblast formulation
US11000310B2 (en) 2010-12-17 2021-05-11 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US10736653B2 (en) 2013-12-06 2020-08-11 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US10967162B2 (en) 2010-12-17 2021-04-06 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
US10702684B2 (en) 2010-12-17 2020-07-07 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
US11278309B2 (en) 2010-12-17 2022-03-22 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11103275B2 (en) 2010-12-17 2021-08-31 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11109887B2 (en) 2013-12-06 2021-09-07 Srgi Holdings, Llc Pixel array medical systems, devices and methods
CA2866563A1 (en) * 2012-03-07 2013-09-12 Fibrocell Technologies, Inc. Topical dermal formulations and methods of personalized treatment of skin
WO2013155109A1 (en) 2012-04-09 2013-10-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for generation of pluripotent and multipotent cells
US20140072611A1 (en) * 2012-09-07 2014-03-13 Fibrocell Technologies, Inc. Methods and Compositions for Treating Post-Cardial Infarction Damage
ITMI20131053A1 (it) * 2013-06-25 2014-12-26 Maria Oliva Salviati Composizione che comprende ortica
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US11229452B2 (en) 2013-12-06 2022-01-25 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11937846B2 (en) 2013-12-06 2024-03-26 Srgi Holdings Llc Pixel array medical systems, devices and methods
EP3579767B1 (en) 2014-10-02 2025-10-08 SRGI Holdings, LLC Pixel array medical systems and devices
EP3253308A4 (en) 2015-02-05 2018-10-24 SRGI Holdings LLC Pixel array medical systems, devices and methods
US11980389B2 (en) 2015-08-31 2024-05-14 Srgi Holdings Llc Handed spiral slotted scalpet array
US11751903B2 (en) 2015-08-31 2023-09-12 Srgi Holdings, Llc Pixel array medical systems, devices and methods
US11490952B2 (en) 2015-08-31 2022-11-08 Srgi Holdings, Llc Pixel array medical devices and methods
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture
WO2017100425A1 (en) * 2015-12-10 2017-06-15 Aesthetics Biomedical, Inc. Topical formulation for skin care
US11564706B2 (en) 2019-10-28 2023-01-31 Srgi Holdings, Llc Pixel array medical systems, devices and methods
WO2018217479A2 (en) 2017-05-11 2018-11-29 Srgi Holdings, Llc Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal
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US20220211767A1 (en) * 2019-04-27 2022-07-07 Figene, Llc Enhancement of fibroblast therapeutic activity by t cell modulation
US12544407B2 (en) 2019-04-28 2026-02-10 Fibrobiologics, Inc. Fibroblast cell therapy for treatment of osteoporosis
CN110075125A (zh) * 2019-05-10 2019-08-02 成都康景生物科技有限公司 一种用于治疗系统性硬化症伴随肢端硬化的脐带间充质干细胞注射液及其制备方法
AU2020387177B2 (en) 2019-11-22 2026-03-12 Cutiss Ag Methods and systems for producing skin grafts
AU2021245671A1 (en) * 2020-03-31 2022-10-20 Cell Exosome Therapeutics Inc. Cell preservation method
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Also Published As

Publication number Publication date
AU2011248067A1 (en) 2012-12-20
JP6309268B2 (ja) 2018-04-11
KR20130060212A (ko) 2013-06-07
AU2011248067B2 (en) 2015-03-12
WO2011140323A1 (en) 2011-11-10
US11554142B2 (en) 2023-01-17
CA2800333A1 (en) 2011-11-10
KR102001254B1 (ko) 2019-07-17
JP2013524856A (ja) 2013-06-20
US20230270793A1 (en) 2023-08-31
EP2566489A1 (en) 2013-03-13
EP2566489B1 (en) 2019-04-24
CN107812014A (zh) 2018-03-20
US8529883B2 (en) 2013-09-10
CN107812014B (zh) 2021-11-16
US20110274665A1 (en) 2011-11-10
US20130295061A1 (en) 2013-11-07
CA2800333C (en) 2018-10-30

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