CN102895150A

CN102895150A - Trichosanthes kirilowii maxim toothpaste

Info

Publication number: CN102895150A
Application number: CN2012103758040A
Authority: CN
Inventors: 刘鹏; 马伟红; 阮雨婷; 余彬倩
Original assignee: Zhejiang Normal University CJNU
Current assignee: Zhejiang Normal University CJNU
Priority date: 2012-09-29
Filing date: 2012-09-29
Publication date: 2013-01-30

Abstract

The invention belongs to daily necessities, and in particular relates to trichosanthes kirilowii maxim toothpaste. The toothpaste is characterized by comprising the following components in percentage by weight: 20 to 25 percent of trichosanthes kirilowii maxim skin extract, 0.1 to 0.6 percent of sorbic acid, 0.1 to 0.3 percent of saccharin, 0.5 to 1.5 percent of carboxymethyl cellulose, 15 to 20 percent of glycerol, 30 to 40 percent of calcium hydrogen phosphate dihydrate, 2 to 3 percent of lauryl sodium sulfonate, 0.3 to 0.8 percent of essence, and the balance of distilled water. The toothpaste has an obvious sterilization effect, meets the requirements for oral health care, has the advantages of resisting cancers, moistening lung, eliminating phlegm, lowering fire and relieving sore throat, does not have toxic or side effect, and is low in manufacturing cost.

Description

Fructus Trichosanthis toothpaste

Technical field

The invention belongs to the daily living article field, be specifically related to a kind of Fructus Trichosanthis toothpaste.

Background technology

At present, along with growth in the living standard, people are also improving day by day to the requirement of oral hygiene.Toothpaste is as dental care products indispensable in people's daily life, only there is the function of cleaning oral cavity, tooth-whitening can not satisfy people far away to the demand of oral hygiene, therefore, various medicated toothpaste with medical health care function arise at the historic moment, existing medicated toothpaste is too numerous to enumerate, Various Functions adds medicine and prevents and treats oral disease, and has a kind of trend that other medical health care functions have become the toothpaste development concurrently in toothpaste.

Fructus Trichosanthis is Cucurbitaceae snake gourd plant, contains saponin, organic acid, fatty oil, saccharide etc. in its fruit, and its effective active composition has antibiotic, anticancer pharmacological action, and its sweet in the mouth, cold in nature, and the effects such as lung moistening is eliminated the phlegm, pathogenic fire reducing sore-throat relieving, promoting the circulation of QI the chest stuffiness relieving are arranged.The adaptability of Fructus Trichosanthis is very strong, and is distributed more widely in China, but the development and use degree is very low, compares with other Chinese herbal medicine with similar medicinal effects, cheap, has good development prospect.

Summary of the invention

For the problems referred to above, the purpose of this invention is to provide a kind ofly to keeping the oral hygiene successful, have other health cares concurrently, the Fructus Trichosanthis toothpaste that cost of manufacture is lower.

The objective of the invention is to realize as follows: a kind of Fructus Trichosanthis toothpaste is characterized in that containing following component (percentage by weight): fruit-rind of Chinese trichosanthes extracting solution 20%～25%, sorbic acid 0.1%～0.6%, glucide 0.1%～0.3%, carboxymethyl cellulose 0.5%～1.5%, glycerol 15%～20%, dicalcium phosphate dehydrate 30%～40%, sodium lauryl sulfonate 2%～3%, essence 0.3%～0.8%, distilled water add to 100%.

Described fruit-rind of Chinese trichosanthes extracting solution manufacture method may further comprise the steps: (1) is put into drying baker with the fruit-rind of Chinese trichosanthes and is dried to constant weight in 60 ℃, pulverizes and cross 30 mesh sieves by pulverizer; (2) get fruit-rind of Chinese trichosanthes dried powder, ratio with every gram fruit-rind of Chinese trichosanthes powder 6mL adds alcoholic solution, reflux, extract, 4 hours, filtration under diminished pressure after refluxing, obtain the fruit-rind of Chinese trichosanthes and extract mixed liquor, with distilled water the fruit-rind of Chinese trichosanthes is extracted the mixed liquor dilution in the ratio of 1:2 again, ethanol is wherein removed in the fruit-rind of Chinese trichosanthes mixed liquor distillation after then will diluting, and can make fruit-rind of Chinese trichosanthes extracting solution.

Analysis and research to fruit-rind of Chinese trichosanthes extract chemical composition show, extract by benzene, can prove and contain triterpene saponin in the extract, and triterpene saponin has the effect of antiinflammatory, anti-blood stasis.Get fruit-rind of Chinese trichosanthes extract and strong sulfuric acid response, generate glaucous chemical compound with the anthrone condensation again, confirm to have oligosaccharide in the extracting solution, oligosaccharide then can not cause dental caries, is conducive to keep oral hygiene.Use GB siderotil development process, confirm to have sterol in the extracting solution, sterol then has certain inhibitory action to tumor.Record several amino acids such as containing serine, cystine, lysine, Aspartic Acid with amino-acid analyzer, and aminoacid can improve immunity, have good eliminate the phlegm, antitumaous effect.Survey fruit-rind of Chinese trichosanthes extract to colibacillary fungistatic effect with the Oxford agar diffusion method, compare inhibition zone result such as following table with ethanol:

By contrast in the upper table as can be known, there is obvious fungistatic effect in fruit-rind of Chinese trichosanthes extract, and the fungistatic effect of fruit-rind of Chinese trichosanthes extract is greater than the fungistatic effect of ethanol.

The above results shows, not only bactericidal effect is obvious for Fructus Trichosanthis toothpaste take fruit-rind of Chinese trichosanthes extract as effective adding ingredient, when satisfying the needs of people to oral health care, also have anticancer, lung moistening is eliminated the phlegm, the pathogenic fire reducing sore-throat relieving, have no side effect, the advantage such as low cost of manufacture.

The specific embodiment

The invention will be further described below in conjunction with embodiment.

Embodiment 1, gets fruit-rind of Chinese trichosanthes extracting solution extracting solution 23kg, dicalcium phosphate dehydrate 36kg, and glycerol 18kg, carboxymethyl cellulose 1.1kg, sorbic acid 0.4kg, sodium lauryl sulfonate 2.6kg,, glucide 0.22kg, essence 0.6kg, distilled water 18.08kg adds up to 100kg.Sorbic acid (antiseptic), glucide, sodium lauryl sulfonate (foaming agent) are dissolved in the fruit-rind of Chinese trichosanthes extracting solution in advance.Again carboxymethyl cellulose (thickening agent) is distributed under high-speed stirred in the glycerol (wetting agent), and mixes with before solution, to uniform state, suitable to there not being obvious granule to exist in the vacuum high-speed stirred.Add dalcium biphosphate (abrasivus), splash into essence high-speed stirred 25 minutes under vacuum state, finish that the vacuum requirement of mastic reaches more than the 0.096MPa before cream processed, finished product is made in fill after finishing.

Embodiment 2, get fruit-rind of Chinese trichosanthes extracting solution extracting solution 20kg, dicalcium phosphate dehydrate 30kg, and glycerol 15kg, carboxymethyl cellulose 0.5kg, sorbic acid 0.1kg, sodium lauryl sulfonate 2.0kg,, glucide 0.1kg, essence 0.3kg, distilled water 32kg adds up to 100kg.After each component weighing is good, make finished product by embodiment 1 identical method.

Embodiment 3, get fruit-rind of Chinese trichosanthes extracting solution extracting solution 25kg, dicalcium phosphate dehydrate 40kg, and glycerol 20kg, carboxymethyl cellulose 1.5kg, sorbic acid 0.6kg, sodium lauryl sulfonate 3.0kg,, glucide 0.3kg, essence 0.8kg, distilled water 8.8kg adds up to 100kg.After each component weighing is good, make finished product by embodiment 1 identical method.

Claims

1. Fructus Trichosanthis toothpaste, it is characterized in that containing following component (percentage by weight): fruit-rind of Chinese trichosanthes extracting solution 20%～25%, sorbic acid 0.1%～0.6%, glucide 0.1%～0.3%, carboxymethyl cellulose 0.5%～1.5%, glycerol 15%～20%, dicalcium phosphate dehydrate 30%～40%, sodium lauryl sulfonate 2%～3%, essence 0.3%～0.8%, distilled water add to 100%.

2. Fructus Trichosanthis toothpaste according to claim 1 is characterized in that described fruit-rind of Chinese trichosanthes extracting solution manufacture method may further comprise the steps: (1) is put into drying baker with the fruit-rind of Chinese trichosanthes and is dried to constant weight in 60 ℃, pulverizes and cross 30 mesh sieves by pulverizer; (2) get fruit-rind of Chinese trichosanthes dried powder, ratio with every gram fruit-rind of Chinese trichosanthes powder 6mL adds alcoholic solution, reflux, extract, 4 hours, filtration under diminished pressure after refluxing, obtain the fruit-rind of Chinese trichosanthes and extract mixed liquor, with distilled water the fruit-rind of Chinese trichosanthes is extracted the mixed liquor dilution in the ratio of 1:2 again, ethanol is wherein removed in the fruit-rind of Chinese trichosanthes mixed liquor distillation after then will diluting, and can make fruit-rind of Chinese trichosanthes extracting solution.