CN104623037A - Medicine for treating tinea manus and pedis - Google Patents

Abstract

The invention relates to a medicine for treating tinea manus and pedis. The medicine is prepared from the following raw medicinal materials in parts by weight: 9 parts of densefruit pittany root-bark, 8 parts of belvedere fruit, 6 parts of bark of Chinese corktree and 15 parts of indigowoad leaf. Clinical experiments prompt that the medicine disclosed by the invention can be safely and effectively applied to the treatment of tinea manus and pedis.

Description

A kind of medicine being used for the treatment of tinea manus and pedis

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of Chinese medicine being used for the treatment of tinea manus and pedis.

Background technology

Tinea manus and pedis refers to that dermatophytosis infringement refers between toe, toe, the infection of the palm caused by sole of the foot portion.In swimming pool and bathhouse, wear public slippers easy infection tinea pedis, the tinea manuum is often by Tinea Pedis.Pathogen is mainly trichophyton, alpha fungus and epidermophyton etc., and infection by Candida albicans is quite a few in recent years sees.

Tinea manus and pedis be betide the palm, the sole of the foot and refer to, the mycotic infection of superficial part of skin between toe.Pathogenic bacterium tinea manus and pedis mainly contains trichophyton, alpha fungus and acrothesium floccosum.

Tinea pedis popular name " tinea pedis ", is again beriberi, tinea pedis.Fungus likes the environment of damp warm, summer sky overabundant heat antiperspirant, wearing rubber overshoes, nylon sock person is hotbed that fungus provides especially; The many improvements of the state of an illness in winter, show as skin cracks.This is a kind of Contagious disease, can the bamboo telegraph because of shared washbasin, foot washing basin, foot towel, towel, slippers and bathtub.

Western medical treatment to employing antifungal medicine for external use topical therapeutic, but easily recurs after drug withdrawal.The traditional Chinese medical science thinks that tinea manus and pedis and tinea corporis and cruris are because skin surface health loses reason, and damp and hot, worm, poison is outer invades caused by skin, therefore control should heat clearing and damp drying, killing parasites for relieving itching.

Medical material present Research involved in the present invention is as follows:

Cortex Dictamni [source] this product is the dry root bark of rutaceae shaggy-fruited dittany Dictamnus dasycarpus Turcz..Spring, Qiu Erji excavate root, and removing silt and rough bark, strip root bark, dry.

[process of preparing Chinese medicine] removing impurity, cleans, slightly moistens, cut sheet, dry.[nature and flavor] are bitter, cold.

[return through] returns spleen, stomach, urinary bladder channel.[function cures mainly] heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.

[usage and dosage] 4.5 ~ 9g; Suitable amount used externally, decoct soup wash or levigation apply.

The Fructus Kochiae [source] this product is the dry mature fruit of chenopod Fructus Kochiae Kochia scoparia (L.) Schrad..To gather during fruit maturation in autumn plant, dry, lay fruit, removing impurity.[nature and flavor] are pungent, bitter, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.[usage and dosage] 8 ~ 15g.Suitable amount used externally, decocts soup fumigation and wash method.[storage] puts aeration-drying place, mothproof.

Cortex Phellodendri [source] this product is the dry bark of rutaceae wampee Phellodendron chinense Schneid. or Cortex Phellodendri Phellodendron amurense Rupr..The former practises title " Cortex Phellodendri ", and the latter practises title " Cortex Phellodendri ".After stripping bark, removing rough bark, dries.[process of preparing Chinese medicine] Cortex Phellodendri: removing impurity, spray clear water, runs through, shredding, dry.[nature and flavor] are bitter, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.[usage and dosage] 3 ~ 12g; Suitable amount used externally.[storage] puts aeration-drying place, moistureproof.

Folium Isatidis [source] this product is the dried leaves of cruciferae isatis Isatis indigotica Fort..In the summer, divide in season in autumn two and gather for 2 ~ 3 times, removing impurity, dries.[process of preparing Chinese medicine] removing impurity, slightly washes, chopping, dry.[nature and flavor] are bitter, cold.[return through] GUIXIN, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.[usage and dosage] 9 ~ 15g.[storage] puts aeration-drying place, mildew-resistant.

Summary of the invention

The present invention aims to provide a kind of medicine being used for the treatment of tinea manus and pedis, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to tinea manus and pedis treatment.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a medicine for tinea manus and pedis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Dictamni 9 parts, the Fructus Kochiae 8 parts, Cortex Phellodendri 6 parts, Folium Isatidis 15 parts.

Inventor, according to the Couple herbs had the deep influence of a scholarly family, understands the main idea that ancient books and records are discussed, and in conjunction with modern medicine to dermopathic pathological study, sums up the present invention, in order to treat tinea manus and pedis.Cortex Dictamni heat clearing and damp drying in side; Fructus Kochiae bitter cold, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, its active component is that the antianaphylaxis pruritus effect of momordin is stronger; Cortex Phellodendri, heat clearing and damp drying, killing parasites for relieving itching, has stronger sensitivity to staphylococcus aureus etc., and bactericidal effect is obvious; Folium Isatidis, bitter in the mouth is cold in nature, heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.All medicines share, and reach effect of heat-clearing and toxic substances removing, dampness removing to stop itchin.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Inventor collects qualified tinea manus and pedis patient 100 example, is divided into 2 groups at random.Treatment group 50 example, man 26 example, female 24 example, age 18-65 year, 35.5 years old mean age, the course of disease 1 month-10 years; Matched group 50 example, man 26 example, female 24 example, age 16-69 year, 32.5 years old mean age, the course of disease 0.5 month-8 years.There is not significant difference, P>0.05 in two groups of sexes, age, courses of disease, has comparability.

1.1 inclusion criteria

(1) in age 16-70 year, men and women does not limit;

(2) patient of tinea manus and pedis is diagnosed as through clinical and mycology microscopy;

(3) patient of this experiment of voluntary participation.

1.2 exclusion standard

(1) gestation and women breast-feeding their children;

(2) to 1% imidazolium nitrate health emulsifiable paste or Chinese herbs decoction allergy sufferers;

Oral or 1 week interior local topical antifungal drug person in (3) 1 months;

(4) immunosuppressant person and diabetics is used.

2, research method

2.1 Therapeutic Method

The tincture that the present invention obtains according to specific embodiment 1 is smeared in treatment group affected part, and after cleaning affected part every day, outer painting is also gently rubbed, 3 times/d.

1% Miconazole Nitrate Cream (trade name: daktarin, Xian-Janssen Pharmaceutical Ltd. produces) is smeared in matched group affected part, and after cleaning affected part every day, outer painting is also gently rubbed, 3 times/d.

All treat 2 weeks for two groups, stop observation post administration 1 week.

2.2 statistical method

Adopt SPSS18.0 statistics software data processing.

3, therapeutic outcome

3.1 criterion of therapeutical effect

By 4 grades of rating methods, recovery from illness: erythra disappears completely, gargalesthesia disappears, negative fungal examination; Effective: deflorescence >=60 %, gargalesthesia obviously alleviates, negative fungal examination; Effective: deflorescence 20% ~ 60%, gargalesthesia alleviates, negative fungal examination or the positive; Invalid: deflorescence <20% or continue to increase the weight of, the same or aggravation of gargalesthesia, fungus microscope examination is positive.

3.2 liang of group curative effects

After treating 2 weeks, treatment group is fully recovered 22 people, effective 18 people, effective 9 people, invalid 1 people, and total effective rate is 98%, after drug withdrawal 1 week, and do not have the case recurred, relapse rate is 0; Matched group is fully recovered 10 people, effective 12 people, effective 19 people, invalid 9 people, and total effective rate is 82%, after drug withdrawal 1 week, and matched group recurrence 6 example, relapse rate is 12%.Two groups of effective percentage compare with relapse rate and there is significant difference, P<0.05, and the curative effect for the treatment of group is better than matched group, and relapse rate is lower than matched group.

Visible, the medicine that the present invention obtains can safe and effective treatment tinea manus and pedis, has good medical science promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Cortex Dictamni 9 grams, the Fructus Kochiae 8 grams, Cortex Phellodendri 6 grams, Folium Isatidis 15 grams; Add 8 times amount 95% ethanol, soak 24 hours, filter; Decompression recycling ethanol is concentrated into 80ml, obtains tincture of the present invention.

Be used for the treatment of tinea manus and pedis.Be applied to affected part, every day 2-4 time.

Claims (1)

1. be used for the treatment of a medicine for tinea manus and pedis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Dictamni 9 parts, the Fructus Kochiae 8 parts, Cortex Phellodendri 6 parts, Folium Isatidis 15 parts.