CN102885302B - Maca composition and preparation method thereof and preparation - Google Patents
Maca composition and preparation method thereof and preparation Download PDFInfo
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- CN102885302B CN102885302B CN201210372052.2A CN201210372052A CN102885302B CN 102885302 B CN102885302 B CN 102885302B CN 201210372052 A CN201210372052 A CN 201210372052A CN 102885302 B CN102885302 B CN 102885302B
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Abstract
The invention discloses a maca composition and a preparation method thereof and a preparation. The maca composition is obtained by using maca, cordyceps militaris and ginseng as raw materials through soaking, circular extraction, separation, concentration, drying, crushing, mixing and tabletting. The method comprises the following steps of: crushing and mixing the maca, the cordyceps militaris and the ginseng, adding water in an amount which is 4 to 10 times weight of the mixture, and soaking for 45 to 75 minutes at the temperature of between 30 and 40 DEG C; circularly extracting for 2 to 4 hours, and filtering to obtain separated liquid; and concentrating and drying the separated liquid in vacuum, and thus obtaining the maca composition. The preparation is powder, capsules, granules, tablets or pills prepared by adding pharmaceutically acceptable accessories into the medicinal composition. By adopting circular extraction in a low-temperature zone, vacuum concentration and microwave drying, active ingredients can be efficiently extracted and are difficultly damaged. The maca composition keeps original mouthfeel and aroma of the maca, the cordyceps militaris and the artificially planted ginseng, and is rich in the active ingredients of the maca, the cordyceps militaris and the artificially planted ginseng.
Description
Technical field
The invention belongs to food processing technology field, be specifically related to one and contain agate coffee, Cordyceps militaris, ginseng effective component, nutritious, mouthfeel is good agate coffee composition and method of making the same and preparation.
Background technology
Agate coffee (Maca), for Cruciferae (Cruciferae) separate row Vegetable spp (Lepidium) plant, have another name called Peruvian ginseng, maka, maca-maca, maino, ayak chichira, ayak willku etc., originate in the mountain area, Andean, South America of 3500 ~ 4500 meters of height above sea level, be mainly distributed in Puno ecotope and Peru the southeastern city of Puno at Peru middle part now.Alpine Economic Plants Inst., Yunnan Prov. Academy of Agricultural Sciences successfully introduced a fine variety agate coffee in 2003 in the more than 3000 meters region of Yunnan part height above sea level, planting technology is comparatively ripe, cultivated area progressively expands, and is mainly distributed in the ground such as Lijing, enlightening celebrating, and its quality and Peru's agate coffee quality compare favourably.Domestic also have TAXKORGAN county, Xinjiang to have plantation.The effects such as agate coffee has the fertility of raising, improves sexual function, anticancer, anti-leukocythemia, treatment climacteric metancholia.Cordyceps militaris, also referred to as northern Chinese caterpillar fungus, northern Chinese caterpillar Fungus, pupa grass or not old grass, belongs to Eumycota, Ascomycetes, Hypocreales, Clavicipitaceae, Cordyceps, is the medicinal fungi of worm, bacterium combination, is mainly grown in the northern area of China.Modern study proves, Cordyceps militaris contains cordycepin (cordycepin), cordycepic acid (PEARLITOL 25C), adenosine, Cordyceps sinensis polysaccharide, ergosterol, superoxide dismutase (SOD), selenium (Se), edible and medical value can match in excellence or beauty with traditional Cordyceps sinensis, has nourishing the lung and the kidney, hemostasis and phlegm, expansion tracheae, calmness, anti-each bacterioid, the effect such as hypotensive.Cordyceps militaris has been realized artificial cultivation, and in the artificial Cordyceps militaris of cultivating, cordycepin content is higher than tens times of Cordyceps sinensis.Ginseng " main tonifying five zang organs, peace spirit, only palpitation with fear, except perverse trend, improving eyesight, happy intelligence development ".In a nutshell, the benefiting action that absolutely proves ginseng is many-sided.Motherland's medical science thinks, the Main Function of ginseng is to reinforce vital energy.In the Su Song of the Song dynasty " Jia Youtu is through book on Chinese herbal medicine opinion ginseng ", just record so one section of word, pass on from one to another " wish is tried two people with walking, and one eats dishes without rice or wine containing ginseng one, respectively walks three or five li and is permitted, and it must not breathed heavily greatly containing ginseng person, containing person's breath freely ".Research discovery, ginseng mainly contains the materials such as saponin, peptide and amino acid, vitamin.What deserves to be explained is, peptide and amino acid are the parts of protein, and protein is one of the mankind's seven large nutritional factors, are the main components that forms human body and even all living things.Therefore say that amino acid and peptide matters are vital to human body.The amino acid that ginseng is contained, tentatively finds, reaches more than 10 and plants.As arginine, asparatate, threonine, serine, glutamic acid, lysine, proline, methionine, glycine, valine, methionine, alanine, phenylalanine etc.In this numerous amino acid, with lysine, methionine, valine, human body is become importantly, they are to form the essential amino acid of human body, meanwhile, be again human body self can not be synthetic amino acid, can only from ingesta, absorb.The traditional Chinese medical science is thought " qi being the governor of blood, blood being the material foundation of QI ", and qi and blood is interdependent, basic each other.Gold dollar Lee doctor Dong Yuan says: " with ginseng, for the person of enriching blood, lid blood is not spontaneous, and the medicine that must must give birth to yang-energy is raw, and sun is raw cloudy long, and blood is prosperous." modern pharmacology also confirms, ginseng energy hematopoietic stimulation function is vigorous.Jing-Yue Complete Works is loaded with two instrument cream, and ginseng for medicinal use, cultivated land are endured cream, and the beneficial gas of two one of medicines, enriches blood for one, complements each other, and brings out the best in each other, and has good benefiting qi for promoting production of blood effect.In addition, the prescription of enriching blood that nourishes blood that ginseng tonic bolus, Renshen Guipi Wan, Bazhen Pills etc. are conventional, has play the same tune on different musical instruments wonderful.Therefore, the diseases such as the lusterless complexion that causes for blood system loss, pale lips, dizzy, lustrelessness of the nails, numb in every limb, small and weak pulse, ginseng is desirable qi-supplementing, blood-engendering medicine.The holy product that ancient medicine is considered as ginseng to promote longevity, current era, some body-building in fashionable market are anti-ageing, medication of prolonging life, as ginseng royal jelly, natural nutrition mouth pond liquid---and the best, Shouwuyishoudan, the long-lived cream of cave heaven, tonic semifluid extract of ten ingredients, ginseng antler medical liquor etc., all be unable to do without ginseng.Chinese scholars studies confirm that, ginseng has the function of the cell ageing of preventing.It has ribonucleic acid, DNA and the synthetic effect of protein of promotion, can strengthen the immunocompetence of body, improves the metaboilic level of body.Therefore, old and feeble and improve the elderly's dizziness, tinnitus cerebri, the symptom such as forgetful, tired for opposing, all there is good effect.Hyperlipemia, blood viscosity increase, and are that disease of old people occurs, the key factor of development.Ginseng can reduce the meeting amount of blood cholesterol and triglycerides, and can suppress platelet aggregation and HDL is increased, thereby plays prevention and delay atherosclerotic good action.Therefore,, for diseases of old people such as hyperlipidemia, coronary heart diseases and angina pectoris, myocardial infarctions, there is certain therapeutic action.It can alleviate in varying degrees or eliminate giddy that this class disease causes, headache, uncomfortable in chest, breathe hard, the symptom such as precordialgia.In prior art, Alpine Economic Plants Inst., Yunnan Prov. Academy of Agricultural Sciences utilizes agate coffee to develop a kind of agate coffee health products, after being mixed by proportioning by raw materials such as agate coffee, rhodiola root, Radix Angelicae Sinensis, make, there is adjusting immunity of human body, improve sexual function, enrich blood adjust blood, anti-oxidant, the effect such as delay senility.Cordyceps militaris is to be usually also used as drug use, or after extracting, makes capsule and take.The inventor considers using agate coffee as carrier, agate coffee, Cordyceps militaris are combined with artificial growth ginseng, form a kind of novel compressing tablet food, can improve the scope of application of agate coffee, Cordyceps militaris, artificial growth ginseng, be very favorable for the exploitation of agate coffee, Cordyceps militaris, artificial growth ginseng.
Summary of the invention
The first object of the present invention is to provide a kind of agate coffee composition that contains agate coffee, Cordyceps militaris, artificial growth ginseng effective component, and the second object is to provide the preparation method of described agate coffee composition, and the 3rd object is to provide the preparation of described agate coffee composition.
The first object of the present invention is achieved in that described agate coffee composition is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains.
The second object of the present invention be achieved in that comprise that raw material is prepared, soaked, circulation is extracted, separate, concentrated and dry, specifically comprise:
A, raw material are prepared: pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves, get by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng;
B, immersion: in mixed material, adding weight ratio is the water of 4～10 times, soaks 45 ~ 75min at 30 ~ 40 DEG C;
C, circulation are extracted: the raw material after immersion obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations;
D, separation: after extracting liquid filtering, obtain parting liquid;
E, concentrate drying: parting liquid to relative density 1.0 ~ 1.3, obtains agate coffee composition at 30 ~ 45 DEG C of Vacuum Concentrations after 40 ~ 50 DEG C of dry 45 ~ 75min.
The present invention's the 3rd object is achieved in that described agate coffee composite preparation is that described pharmaceutical composition adds pharmaceutically acceptable auxiliary material to make powder, capsule, granule, tablet or pill.
The present invention extracts jointly with agate coffee, Cordyceps militaris and artificial growth ginseng mixed material, and the agate coffee sheet of preparation is tablet.Described agate coffee is the agate coffee of processing through completing; Described Cordyceps militaris is the Cordyceps militaris of processing through completing; Described artificial growth ginseng is the artificial growth ginseng of processing through completing.Utilize modern extraction technique, the extraction that circulates in low-temperature region, Vacuum Concentration and microwave drying, not only make the active ingredient energy high efficiency extraction of agate coffee, Cordyceps militaris and ginseng out, and active ingredient is also difficult for being damaged.Evidence: agate coffee sheet of the present invention has retained original mouthfeel and the fragrance of agate coffee, Cordyceps militaris, artificial growth ginseng, and the active component that contains abundant agate coffee and Cordyceps militaris, artificial growth ginseng.
Brief description of the drawings
Fig. 1 is process chart of the present invention.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, but never in any form the present invention is limited, and any conversion or the improvement done based on training centre of the present invention, all fall into protection scope of the present invention.
As shown in Figure 1, agate coffee composition of the present invention is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains.
The method of agate coffee composition of the present invention, comprises raw material preparation, immersion, circulation extraction, separates, concentrates and be dried, and specifically comprises:
It is that pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves that described raw material is prepared, and gets by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng; Described immersion is to be the water of 4～10 times by adding weight ratio in mixed material, soaks 45 ~ 75min at 30 ~ 40 DEG C; Described circulation extraction is that the raw material after soaking obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations; Described separation is after extracting liquid filtering, to obtain parting liquid; Described concentrate drying be parting liquid at 30 ~ 45 DEG C of Vacuum Concentrations to relative density 1.0 ~ 1.3, after 40 ~ 50 DEG C of dry 45 ~ 75min agate coffee composition.
Described raw material preparation process agate coffee, Cordyceps militaris, ginseng are artificial growth, described 1 ~ 3 part of 5 ~ 7 parts of agate coffees, Cordyceps militaris, 1 ~ 3 part of ginseng.
Described soaking step soaking temperature is 30 ~ 40 DEG C; Be preferably 35 DEG C.
It is 50 ~ 70 DEG C that temperature is extracted in described circulation extraction step circulation; Be preferably 60 DEG C.
Described separating step is separated into extract natural sedimentation 2 ~ 3h and obtains parting liquid.
Described separating step is separated into after extract natural sedimentation 2 ~ 3h, and supernatant is separated to obtain to parting liquid at 10000 ~ 40000r/min high speed centrifugation; Rotating speed is preferably 34000 ~ 36000r/min.
Described concentrate drying step Vacuum Concentration temperature is 30 ~ 50 DEG C; Be preferably 40 DEG C.
Described concentrate drying step is dry is in 45 DEG C of microwave dryings or freeze drying, and be 50 ~ 70min drying time; Be preferably 60min.
Described composite preparation is that described pharmaceutical composition adds pharmaceutically acceptable auxiliary material to make powder, capsule, granule, tablet or pill.
Operation principle of the present invention:
The present invention utilizes modern extraction technique, and the extraction that circulates in low-temperature region, Vacuum Concentration and microwave drying not only make the active ingredient energy high efficiency extraction of agate coffee, Cordyceps militaris and artificial growth ginseng out, and active ingredient are also difficult for being damaged.
Embodiment 1:
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 mesh sieves, 60 kilograms of agate coffees, 20 kilograms of Cordyceps militaris, 20 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 4 water, at 30 DEG C, soaks 45min; Raw material after immersion obtains extract after 2h is extracted in 50 DEG C of circulations; Extracting liquid filtering separates, and parting liquid is at 30 DEG C of Vacuum Concentrations to relative density 1.0, and concentrate obtains objective composition at 40 DEG C of microwave drying 45min.
Embodiment 2
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 50 mesh sieves, 70 kilograms of agate coffees, 20 kilograms of Cordyceps militaris, 10 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 6 water, at 40 DEG C, soaks 75min; Raw material after immersion obtains extract after circulating at 70 DEG C and extracting 4h; Extracting liquid filtering separates, and parting liquid is at 45 DEG C of Vacuum Concentrations to relative density 1.3, and concentrate obtains objective composition at 50 DEG C of freeze drying 75min.
Embodiment 3
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 60 mesh sieves, 60 kilograms of agate coffees, 20 kilograms of Cordyceps militaris, 20 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 8 water, at 35 DEG C, soaks 60min; Raw material after immersion obtains extract after circulating at 60 DEG C and extracting 3h; Extracting liquid filtering separates, and parting liquid is at 35 DEG C of Vacuum Concentrations to relative density 1.3, and concentrate obtains objective composition at 45 DEG C of microwave drying 60min.
Embodiment 4
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 70 mesh sieves, 80 kilograms of agate coffees, 10 kilograms of Cordyceps militaris, 10 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 6 water, soaks 45min at 30 DEG C; Raw material after immersion obtains extract after 2h is extracted in 50 DEG C of circulations; After extract natural sedimentation 2h, obtain parting liquid, parting liquid is at 30 DEG C of Vacuum Concentrations to relative density 1.2, and concentrate obtains objective composition at 40 DEG C of freeze drying 45min.
Embodiment 5
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 80 mesh sieves, 70 kilograms of agate coffees, 15 kilograms of Cordyceps militaris, 15 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 8 water, soaks 75min at 40 DEG C; Raw material after immersion obtains extract after 4h is extracted in 70 DEG C of circulations; After extract natural sedimentation 3h, obtain parting liquid, parting liquid is at 45 DEG C of Vacuum Concentrations to relative density 1.0, and concentrate obtains objective composition at 50 DEG C of microwave drying 75min.
Embodiment 6
Agate coffee, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 mesh sieves, 70 kilograms of agate coffees, 10 kilograms of Cordyceps militaris, 20 kilograms of mixing of artificial growth ginseng; In mixed material, adding weight ratio is 7 water, soaks 60min at 35 DEG C; Raw material after immersion obtains extract after 3h is extracted in 60 DEG C of circulations; After extract natural sedimentation 2.5h, obtain parting liquid, parting liquid is at 40 DEG C of Vacuum Concentrations to relative density 1.2, and concentrate obtains objective composition at 45 DEG C of freeze drying 60min.
Embodiment 7
Get any one pharmaceutical composition in embodiment 1 ~ 6, add pharmaceutically acceptable auxiliary material, packing is powder.
Embodiment 8
Get any one pharmaceutical composition in embodiment 1 ~ 6, add pharmaceutically acceptable auxiliary material, through granulating, drying, be filled in capsule, obtain capsule.
Embodiment 9
Get any one pharmaceutical composition in embodiment 1 ~ 6, add pharmaceutically acceptable auxiliary material, through granulating, drying, obtain granule.
Embodiment 10
Get any one pharmaceutical composition in embodiment 1 ~ 6, add pharmaceutically acceptable auxiliary material, through granulation, compressing tablet, obtain tablet.
Embodiment 11
Get any one pharmaceutical composition in embodiment 1 ~ 6, add pharmaceutically acceptable auxiliary material, pill, oven dry, obtain pill.
Claims (6)
1. an agate coffee composition, is characterized in that described agate coffee composition is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains; Its preparation method comprises raw material preparation, immersion, circulation extraction, separates, concentrates and be dried, and is specially:
A, raw material are prepared: pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves, get by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng;
B, immersion: in mixed material, adding weight ratio is the water of 4 ~ 10 times, soaks 45 ~ 75min at 30 ~ 40 DEG C;
C, circulation are extracted: the raw material after immersion obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations;
D, separation: after extracting liquid filtering, obtain parting liquid;
E, concentrate drying: parting liquid to relative density 1.0 ~ 1.3, obtains agate coffee composition at 30 ~ 45 DEG C of Vacuum Concentrations after 40 ~ 50 DEG C of dry 45 ~ 75min.
2. an agate coffee composition, is characterized in that described agate coffee composition is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains; Its preparation method comprises raw material preparation, immersion, circulation extraction, separates, concentrates and be dried, and is specially:
A, raw material are prepared: pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves, get by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng;
B, immersion: in mixed material, adding weight ratio is the water of 4 ~ 10 times, soaks 45 ~ 75min at 30 ~ 40 DEG C;
C, circulation are extracted: the raw material after immersion obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations;
D, separation: extract natural sedimentation 2 ~ 3h obtains parting liquid;
E, concentrate drying: parting liquid to relative density 1.0 ~ 1.3, obtains agate coffee composition at 30 ~ 45 DEG C of Vacuum Concentrations after 40 ~ 50 DEG C of dry 45 ~ 75min.
3. an agate coffee composition, is characterized in that described agate coffee composition is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains; Its preparation method comprises raw material preparation, immersion, circulation extraction, separates, concentrates and be dried, and is specially:
A, raw material are prepared: pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves, get by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng;
B, immersion: in mixed material, adding weight ratio is the water of 4 ~ 10 times, soaks 45 ~ 75min at 30 ~ 40 DEG C;
C, circulation are extracted: the raw material after immersion obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations;
D, separation: after extract natural sedimentation 2 ~ 3h, supernatant is separated to obtain to parting liquid at 10000 ~ 40000r/min high speed centrifugation;
E, concentrate drying: parting liquid to relative density 1.0 ~ 1.3, obtains agate coffee composition at 30 ~ 45 DEG C of Vacuum Concentrations after 40 ~ 50 DEG C of dry 45 ~ 75min.
4. according to the agate coffee composition described in claim 1,2 or 3, it is characterized in that dry described in E step is 45 DEG C of microwave dryings, be 50 ~ 70min drying time.
5. an agate coffee composition, is characterized in that described agate coffee composition is taking agate coffee, Cordyceps militaris and ginseng as raw material, after immersion, circulation are extracted, separate, concentrate, are dried, pulverize, are mixed, obtains; Its preparation method comprises raw material preparation, immersion, circulation extraction, separates, concentrates and be dried, and is specially:
A, raw material are prepared: pueraria root powder, Cordyceps militaris, ginseng pulverate are broken to and can cross 40 ~ 60 mesh sieves, get by weight 6 ~ 8 parts of agate coffees, 1 ~ 2 part of Cordyceps militaris, 1 ~ 2 part of mixing of ginseng;
B, immersion: in mixed material, adding weight ratio is the water of 4 ~ 10 times, soaks 45 ~ 75min at 30 ~ 40 DEG C;
C, circulation are extracted: the raw material after immersion obtains extract after 2 ~ 4h is extracted in 50 ~ 70 DEG C of circulations;
D, separation: after extracting liquid filtering, obtain parting liquid;
E, concentrate drying: parting liquid to relative density 1.0 ~ 1.3, obtains agate coffee composition at 30 ~ 45 DEG C of Vacuum Concentrations after freeze drying 50 ~ 70min.
6. a preparation of being made up of the agate coffee composition described in claim 1,2,3 or 5, is characterized in that described preparation is that described agate coffee composition adds pharmaceutically acceptable auxiliary material to make powder, capsule, granule, tablet or pill.
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| CN102599513A (en) * | 2012-03-26 | 2012-07-25 | 张丽琴 | Health food containing maca and Cordyceps sinensis |
| CN102613555A (en) * | 2012-03-30 | 2012-08-01 | 石药集团中奇制药技术（石家庄）有限公司 | Maca powder and ginseng composition and preparation method thereof |
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| CN1390476A (en) * | 2002-07-30 | 2003-01-15 | 杨亚军 | Health-care food and its preparing process |
| DE202008005965U1 (en) * | 2008-04-30 | 2008-12-11 | Metsälä, Pertti | food composition |
| CN101401651A (en) * | 2008-10-20 | 2009-04-08 | 宋福兴 | Culinary Chinese medicinal composition |
| CN102551066A (en) * | 2012-03-26 | 2012-07-11 | 张丽琴 | Health-care food containing maca, cordyceps and truffle |
| CN102599513A (en) * | 2012-03-26 | 2012-07-25 | 张丽琴 | Health food containing maca and Cordyceps sinensis |
| CN102613555A (en) * | 2012-03-30 | 2012-08-01 | 石药集团中奇制药技术（石家庄）有限公司 | Maca powder and ginseng composition and preparation method thereof |
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