CN105998245A - Traditional Chinese medicine for improving male sexual functions, and products thereof - Google Patents
Traditional Chinese medicine for improving male sexual functions, and products thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention discloses a traditional Chinese medicine composition for improving the male sexual functions, and products thereof. The traditional Chinese medicine composition comprises, by weight, 1-50 parts of Lepidium meyenii, 1-20 parts of ginseng, 1-20 parts of raspberries, 1-20 parts of radix bardanae and 1-20 parts of Cordyceps militaris. A decoction, a pill, a dripping pill, a granule, a tablet, a hard capsule, a soft capsule, an electuary, a syrup, an oral liquid, a tea substitute, a beverage and a solid beverage made from the traditional Chinese medicine composition has a male sexual function improving effect, and can be used to treat impotence, premature ejaculation and other male sexual disfunctions. The invention also discloses various traditional Chinese medicinal products for improving the male sexual functions.
Description
Technical field
The present invention relates to Chinese medicinal formulae field, be specifically related to a kind of Chinese medicine improving male's sexual and use this Chinese medicine system
Become has the goods improving male's sexual effect.
Background technology
Along with improving constantly of national life level, increasing male begins to focus on the health problem of self, simultaneously
Between man and wife, harmony increasingly comes into one's own, and wherein affects the sexual function that a most important factor harmonious between man and wife is exactly male
Obstacle.Male sexual disorder refers in five stages of the sexual activitys such as libido, erection, sexual intercourse, orgasm, ejaculation,
Wherein certain stage or several stage or all stage occur abnormal and affect sexual activity, wherein erection disturbance (ED) and morning
Letting out is the most modal male sexual disorder.
China's male reproductive health situation faces severe situation at present, and sexual dysfunction presents the highest sickness rate, has
People's report up to 25%, but male patient shows " male chauvinism " mostly, and it was the most both treated the most very by patient
Worry, feel again to be ashamed to mention, so the few can select treatment, cause the state of an illness more serious.Sexual dysfunction patient may
Than ordinary person, his sexual life more dissatisfied, is difficult to loosen in sexual intercourse, and Regularity of sexual activity is relatively low, meanwhile, to other aspects also
Have a negative impact, such as self-confidence and sex partner relation etc., it is possible to cause worry, anxiety, the mental symptom such as dejected and depressed,
Drastically influence the quality of life of male, cause family friction humorous.
Sexual dysfunction is all the most serious strike for any one man, and this is accomplished by being strengthened by media
The dynamics of publicity, allows society focus more on the sexual function of male, pays close attention to the health of male, it is often more important that allow male patient oneself
Recognize the seriousness of sexual dysfunction, create the sexual life of harmony, harmonious family for patient.
The medicine for the treatment of male sexual disorder can be divided into two big classes at present: (1) is with viagra, Xi Aili, Ai Lida, gold
The Western medicine that Ge Wei represents, (2) Chinese patent medicine with LIUWEI DIHUANG WAN, GUIFU DIHUANG WAN, JINGUI SHENQI WAN as representative.Additionally, strength wine,
The health foods such as YEDAO LUGUI JIU also have the effect of the male's sexual that has some improvement.
Compare with the Western medicine of existing treatment male sexual disorder, the prescription improving male's sexual disclosed by the invention
Agent is based on integrally-regulated, though taking effect be not as rapid as Western medicine, but has untoward reaction long-term taking, safe and reliable, valency few, applicable
The advantages such as lattice are cheap.
With the Chinese patent medicine of existing treatment male sexual disorder and improve the health food of male's sexual and compare, the present invention
Disclosed Chinese medicinal formulae prescription is rigorous, science, by " Peru's Radix Ginseng ", " plant viagra " Lepidinm meyenii Walp and yang-tonifying drug, the same use of drugs for nourishing yin, body
Show traditional Chinese medical science tonifying both YIN and YANG, mend the double cube principle executed of row.Raw materials used be the product that sweet warm nature is flat, mild in medicine property and, it is to avoid
The damage to body of the big the driest warm product, all body constitution crowds all can use.
Summary of the invention
The present invention provides a kind of Chinese medicine improving male's sexual, and raw material is easy to get, and preparation is convenient, has and improves Male sexual merit
The effect of energy, can be used for the male sexual disorder such as sexual impotence, premature ejaculation.
In order to achieve the above object, the technical scheme that the present invention provides is: the described Chinese prescription improving male's sexual
It is made up of the raw material of following weight portion:
Lepidinm meyenii Walp 1~50 parts, Radix Ginseng 1~20 parts, Fructus Rubi 1~20 parts, Radix Arctii 1~20 parts, Cordyceps militaris (L.) Link. 1~20 parts.
Preferably, the parts by weight of described Lepidinm meyenii Walp are 1~20 part;It is further preferable that the parts by weight of described Lepidinm meyenii Walp be 4~
8 parts;Most preferably, the parts by weight of described Lepidinm meyenii Walp are 6 parts.
Preferably, the parts by weight of described Radix Ginseng are 1~10 part;It is further preferable that the parts by weight of described Radix Ginseng be 1~
5 parts;Most preferably, the parts by weight of described Radix Ginseng are 3 parts.
Preferably, the parts by weight of described Fructus Rubi are 1~10 part;It is further preferable that the parts by weight of described Fructus Rubi
It it is 2~6 parts;Most preferably, the parts by weight of described Fructus Rubi are 4 parts.
Preferably, the parts by weight of described Radix Arctii are 1~10 part;It is further preferable that the parts by weight of described Radix Arctii
It it is 2~6 parts;Most preferably, the parts by weight of described Radix Arctii are 4 parts.
Preferably, the parts by weight of described Cordyceps militaris (L.) Link. are 1~10 part;It is further preferable that the parts by weight of described Cordyceps militaris (L.) Link.
It it is 1~3 part;Most preferably, the parts by weight of described Cordyceps militaris (L.) Link. are 2 parts.
Preferably, described Chinese prescription is made up of the raw material of following weight portion:
Lepidinm meyenii Walp 1~20 parts, Radix Ginseng 1~10 parts, Fructus Rubi 1~10 parts, Radix Arctii 1~10 parts, Cordyceps militaris (L.) Link. 1~10 parts.
Preferably, described Chinese prescription is made up of the raw material of following weight portion:
Lepidinm meyenii Walp 4~8 parts, Radix Ginseng 1~5 parts, Fructus Rubi 2~6 parts, Radix Arctii 2~6 parts, Cordyceps militaris (L.) Link. 1~3 parts.
Preferably, described Chinese prescription is made up of the raw material of following weight portion:
Lepidinm meyenii Walp 6 parts, Radix Ginseng 3 parts, Fructus Rubi 4 parts, Radix Arctii 4 parts, Cordyceps militaris (L.) Link. 2 parts.
The invention also discloses a kind of Chinese medicine product improving male's sexual, described Chinese medicine product is by above-mentioned Chinese medicine
Prescription decocting is boiled into the decoction that agent prepares.
The invention also discloses a kind of Chinese medicine product improving male's sexual, described Chinese medicine product is (such as water with solvent
Or ethanol) extract the extractum that above-mentioned Chinese prescription obtains, or pulverize after the powder that above-mentioned Chinese prescription obtains adds adjuvant
Through existing corresponding technique prepare pill, drop pill, granule, tablet, hard capsule, soft capsule, soft extract, syrup,
Oral liquid.
Invention additionally discloses a kind of Chinese medicine product improving male's sexual, described Chinese medicine product is by Claims 1 to 4
Chinese prescription described in any one is size-reduced, decoct, concentrate, pelletize, be dried, pack after prepare alternative tea.
Invention additionally discloses a kind of Chinese medicine product improving male's sexual, described Chinese medicine product is by Claims 1 to 4
The Chinese prescription described in any one filtrate through decocting, being filtrated to get prepares through dosing, sterilizing, fill after adding water and adjuvant
Beverage, or added water and auxiliary by the extractum through decocting, filter, being concentrated to give of the Chinese prescription described in any one of Claims 1 to 4
The beverage prepared through dosing, sterilizing, fill after material.
Invention additionally discloses a kind of Chinese medicine product improving male's sexual, described Chinese medicine product is by Claims 1 to 4
Chinese prescription described in any one is after decocting, filter, concentrate, pelletize (one-step palletizing, boiling granulating or wet granulation), packaging
The solid beverage prepared.
Below in conjunction with principle, the invention will be further described:
The Chinese medicine improving male's sexual disclosed by the invention, by Lepidinm meyenii Walp, Radix Ginseng, Fructus Rubi, Radix Arctii, Cordyceps militaris (L.) Link. by closing
Suitable proportioning composition.This Chinese medicinal formulae is in strict accordance with Chinese medical theory, according to the nature and flavor of each single medicinal material, Gui Jing, effect, according to
The combination principle of " monarch, minister, help, make " is drafted.
Radix Ginseng: monarch drug.Slightly warm in nature, sweet in the mouth, micro-hardship.Strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid and nourishes blood, benefit of calming the nerves
Intelligence.Radix Ginseng has the strong effect of obvious tonification, and the traditional Chinese medical science is thought, gas is sun, and blood is cloudy, ginseng qi-tonifying, it is simply that YANG invigorating, Gu Rencan
Having with yang-tonifying drug more and share, the traditional Chinese medical science uses Radix Ginseng tonifying YANG, treatment impotence due to deficiency of the kidney, the example of hyposexuality to have it from ancient times.Lepidinm meyenii Walp: minister
Medicine.Fatigue alleviating, strengthens energy, muscle power, enhancing immunity, improves sexual function, improves fertility, endocrine regulation system.Cover
Basin: adjuvant drug.Warm in nature, sweet in the mouth, acid.Supplementing the kidney to control the nocturnal reducing urination, nourishing the liver to improve visual acuity.Cordyceps militaris (L.) Link.: make medicine.Property flat, sweet in the mouth.Radix Arctii: make
Medicine.Cold in nature, bitter in the mouth.Cordyceps militaris (L.) Link., Radix Arctii can stabilize the property of Radix Ginseng, Lepidinm meyenii Walp, the temperature of Fructus Rubi, heat in we, play harmonizing drug
The effect of property.
Whole reasonable recipe, rigorous, the medicine of multiple dosage form, alternative tea, beverage, solid beverage can be prepared as, raw material is easy
, preparation technology is relatively easy, and cost can be controlled.
Detailed description of the invention
In order to make those skilled in the art be more fully understood that technical scheme, below by specific embodiment
The present invention is described in further detail.
The Chinese prescription improving male's sexual disclosed by the invention is made up of the raw material of following weight portion:
Lepidinm meyenii Walp 1~50 parts, Radix Ginseng 1~20 parts, Fructus Rubi 1~20 parts, Radix Arctii 1~20 parts, Cordyceps militaris (L.) Link. 1~20 parts.
The decoction be made up through certain technique of above-mentioned raw materials, pill, drop pill, granule, tablet, hard capsule, soft capsule
Agent, soft extract, syrup, tincture, oral liquid, alternative tea, beverage, solid beverage are respectively provided with heat clearing away of driving away summer heat, supplementing QI for promoting the production of body fluid, spleen invigorating
The effect help digestion, detoxified, basic reason is that this Chinese medicinal formulae is to draft in strict accordance with Chinese medical theory, plurality of raw materials therein
Medicine can reach " mutual reinforcement between ", the effect of " making mutually ".
With specific embodiment, technical solution of the present invention is described below, but protection scope of the present invention is not by following example
Restriction.
The decoction of embodiment 1 present invention
Take Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1~20 grams
(Lepidinm meyenii Walp, Radix Ginseng, Radix Arctii shave), adds suitable quantity of water and soaks 0.5 hour, and boiling with soft fire 1 hour filters, obtains decoction.
The alternative tea of embodiment 2 present invention
Take Lepidinm meyenii Walp 1~20 grams, Radix Ginseng 1~10 grams, Fructus Rubi 1~10 grams, Radix Arctii 1~10 grams, Cordyceps militaris (L.) Link. 1~10 grams,
It is respectively crushed into the coarse granule of 10~14 mesh, mixing, coarse granule is loaded teabag filter bag, every packed 6g, sealing, obtains alternative
Tea.
The hard capsule of embodiment 3 present invention
Take Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1~20 grams
(Lepidinm meyenii Walp, Radix Ginseng, Radix Arctii shave), adds 15 times amount soak by water 2 times, each 1 hour (keeping micro-boiling 1 hour), and decocting liquid filters,
Merging 2 filtrates, being concentrated into relative density is 1.15 (80 DEG C of heat are surveyed), obtains runny plaste;Runny plaste adds suitable amount of sucrose powder, mixing, system
Grain (14 mesh sieve), dries 3 hours in 80 DEG C, obtains granule;Granule is loaded capsule shells, every capsule dress 0.3g, obtains hard capsule.
The tablet of embodiment 4 present invention
Take Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1~20 grams
(Lepidinm meyenii Walp, Radix Ginseng, Radix Arctii shave), adds 20 times amount water soaking 0.5 hour, heated and boiled 1 hour, filters, and filtrate is concentrated into
Relative density is 1.10 (80 DEG C of heat are surveyed), obtains runny plaste;Runny plaste adds suitable amount of sucrose powder, maltodextrin, mixing, (16 mesh of pelletizing
Sieve), gained granule dries 4 hours in 75 DEG C, is pressed into element sheet (every tablet weight 0.5 gram), film coating, obtains tablet.
The water-honeyed pill of embodiment 5 present invention
Take Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1~20
Gram, it being respectively crushed into powder (crossing 80 mesh sieves), mixing, every 100 grams of powder refined honeys 75 grams add appropriate water pill, in 70 DEG C of bakings
6 hours, obtain water-honeyed pill.
The oral liquid of embodiment 6 present invention
Take Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1~20 grams
(Lepidinm meyenii Walp, Radix Ginseng, Radix Arctii shave), adds 15 times amount water soaking 0.5 hour, heated and boiled 1 hour, filters, and filtering residue adds 10 again
Times amount water boil 0.5 hour, filters, and merges secondary filtrate, is condensed into runny plaste, adds certain density simple syrup in right amount, stirs evenly,
Cooling, adds water to 2000 milliliters, stirs evenly, and stands, and filters, embedding, obtains oral liquid.
The beverage of embodiment 7 present invention
Take Lepidinm meyenii Walp 4~8 kilograms, Radix Ginseng 1~5 kilograms, Fructus Rubi 2~6 kilograms, Radix Arctii 2~6 kilograms, Cordyceps militaris (L.) Link. 1~3
Kilogram (Lepidinm meyenii Walp, Radix Ginseng, Radix Arctii shave), adds 20 times amount water soaking 0.5 hour, heated and boiled 1 hour, filters, and filtrate adds
Enter suitable quantity of water, white sugar, mixing, it is configured to 1000 liters, sterilizing, fill, obtain beverage.
The drug efficacy study result of embodiment 8 present invention
1 experiment material
1.1 test medicine and positive control drug
Test medicine: Lepidinm meyenii Walp 1~50 grams, Radix Ginseng 1~20 grams, Fructus Rubi 1~20 grams, Radix Arctii 1~20 grams, Cordyceps militaris (L.) Link. 1
~20 grams, Lepidinm meyenii Walp breaks into fine powder (cross 80 mesh sieves), and remaining 4 taste adds 7 times amount water soaking 0.5 hour, decocts that (boiled meter 1 hour
Time), filtering, filtering residue adds 5 times amount soak by water 1 hour (timing of having boiled) again, filters, merging filtrate, is concentrated into appropriate, adds Lepidinm meyenii Walp
Powder, mixing, weigh, record weight, standby.
Test medicine is equivalent to crude drug amount 0.64g crude drug/ml, by the clinical first Affiliated Hospital center of Hunan University of Traditional Chinese Medicine
Laboratory provides.Day for human beings usual amounts is 34g/ day.
Positive control drug Sildenafil citrate tablets, pfizer inc produces, specification: 0.1g, authentication code: state
Medicine quasi-word H20020528, lot number: L22968.Day for human beings usual amounts is 0.1g.
1.2 laboratory animal
ICR mice, SPF level, male 40, age in days 48-52 days, female 120, age in days 48-52 days.By Hunan Si Laike
Jing Da laboratory animal company limited provides, the quality certification number: No.43004700016184.Credit number: SCXK (Hunan) 2011-
0003。
1.3 instrument and equipment
AY-120 electronic analytical balance, Japan's Shimadzu;DJ-10002 electronic balance, the limited public affairs of Foochow China will scientific instrument
Department.
2 experimental techniques
2.1 packet
40 male mices are randomly divided into blank group, Sildenafil citrate tablets group, test medicine 2 times, 1 multiple dose group altogether
4 groups, often group 10.
2.2 be administered
Each experimental group gavage every day 1 time, test medicine group gives different medicinal liquid gavages, ground, positive controls gavage west that
The distilled water of the capacity such as non-solution, blank group gavage.Every day 1 time, continuous 21 days.
2.3 index observing
30min after last is administered, takes female mice by 3:1 and mates with male mice, is placed in dark indoor observation, and record is each
Number of copulations in the copulation incubation period (i.e. mating the time to first time copulation) of male Mus and 20min.
2.4 statistical method
Measurement data withRepresent, use and between the statistical procedure group in EXCEL, compare t inspection, it is judged that be poor between group
Different significance.
3 experimental results (are shown in Table 1)
Comparing with matched group, sldenafil group and test medicine 2 multiple dose group mice number of copulations substantially increase, and difference has
Statistics is had to anticipate (P < 0.05 or P < 0.01).
4 conclusions
Test medicine 2 multiple dose (8.84g/kg) has the effect improving sexual function, but test medicine 1 multiple dose is invalid.
Table 1 improves sexual function food to mice number of copulations and preclinical impact
Note: compare with matched group: * P < 0.05, * * P < 0.01.
Claims (10)
1. the Chinese prescription improving male's sexual, it is characterised in that described Chinese prescription is by the raw material of following weight portion
Composition:
Lepidinm meyenii Walp 1~50 parts, Radix Ginseng 1~20 parts, Fructus Rubi 1~20 parts, Radix Arctii 1~20 parts, Cordyceps militaris (L.) Link. 1~20 parts.
The Chinese prescription improving male's sexual the most according to claim 1, it is characterised in that described Chinese prescription by with
The raw material composition of lower weight portion:
Lepidinm meyenii Walp 1~20 parts, Radix Ginseng 1~10 parts, Fructus Rubi 1~10 parts, Radix Arctii 1~10 parts, Cordyceps militaris (L.) Link. 1~10 parts.
The Chinese prescription improving male's sexual the most according to claim 2, it is characterised in that described Chinese prescription by with
The raw material composition of lower weight portion:
Lepidinm meyenii Walp 4~8 parts, Radix Ginseng 1~5 parts, Fructus Rubi 2~6 parts, Radix Arctii 2~6 parts, Cordyceps militaris (L.) Link. 1~3 parts.
The Chinese prescription improving male's sexual the most according to claim 3, it is characterised in that described Chinese prescription by with
The raw material composition of lower weight portion:
Lepidinm meyenii Walp 6 parts, Radix Ginseng 3 parts, Fructus Rubi 4 parts, Radix Arctii 4 parts, Cordyceps militaris (L.) Link. 2 parts.
5. according to the Chinese prescription improving male's sexual described in any one of Claims 1 to 4, it is characterised in that in described
Medicine prescription make decoction, pill, drop pill, granule, tablet, hard capsule, soft capsule, soft extract, syrup, oral liquid or
Beverage.
6. the Chinese medicine product improving male's sexual, it is characterised in that described Chinese medicine product is to be appointed by Claims 1 to 4
One described Chinese prescription decocting is boiled into the decoction that agent prepares.
7. the Chinese medicine product improving male's sexual, it is characterised in that described Chinese medicine product is to extract right with solvent to want
Seek the extractum that the Chinese prescription described in 1~4 any one obtains, or the Chinese prescription that pulverizing is described in any one of Claims 1 to 4 obtains
The powder that arrives add pill that adjuvant prepares, drop pill, granule, tablet, hard capsule, soft capsule, soft extract, syrup,
Oral liquid.
8. the Chinese medicine product improving male's sexual, it is characterised in that described Chinese medicine product is to be appointed by Claims 1 to 4
One described Chinese prescription is size-reduced, decoct, concentrate, pelletize, be dried, pack after the alternative tea for preparing.
9. the Chinese medicine product improving male's sexual, it is characterised in that described Chinese medicine product is to be appointed by Claims 1 to 4
The drink that one described Chinese prescription filtrate through decocting, being filtrated to get prepares through dosing, sterilizing, fill after adding water and adjuvant
Material, or added water and adjuvant by the extractum through decocting, filter, being concentrated to give of the Chinese prescription described in any one of Claims 1 to 4
The beverage prepared by dosing, sterilizing, fill.
10. the Chinese medicine product improving male's sexual, it is characterised in that described Chinese medicine product is to be appointed by Claims 1 to 4
The solid beverage that one described Chinese prescription prepares after decocting, filter, concentrate, pelletize, packing.
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Cited By (4)
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CN107496705A (en) * | 2017-10-11 | 2017-12-22 | 湖南橘色科技有限责任公司 | A kind of ginseng oyster cream and preparation method thereof |
CN108514110A (en) * | 2018-06-27 | 2018-09-11 | 天津活力达生物科技有限公司 | A kind of composition of the raspberry of Cordyceps militaris containing ginseng and its application |
CN108634316A (en) * | 2018-05-24 | 2018-10-12 | 哈福科技(武汉)集团有限公司 | A kind of functional food and preparation method thereof improving sexual function |
CN113170845A (en) * | 2021-05-13 | 2021-07-27 | 山东译青春生物科技有限公司 | Food formula for improving male energy and preparation method thereof |
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