CN102860973B - Toothpaste for repairing damaged tooth - Google Patents
Toothpaste for repairing damaged tooth Download PDFInfo
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- CN102860973B CN102860973B CN 201210403877 CN201210403877A CN102860973B CN 102860973 B CN102860973 B CN 102860973B CN 201210403877 CN201210403877 CN 201210403877 CN 201210403877 A CN201210403877 A CN 201210403877A CN 102860973 B CN102860973 B CN 102860973B
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Abstract
The invention belongs to the field of daily necessities and discloses a tube of toothpaste for repairing a damaged tooth. The toothpaste is composed of a abrasive agent, a wet storage agent, an adhesive agent, a surface active agent, a sweetening agent, other active additive agents and an flavoring agent, the abrasive agent includes one or two of pearl powders, nacreous powders, calcium carbonate, dicalcium phosphate, calcium pyrophosphate, silica and aluminum hydroxide, wherein the content of the pearl powders is 30%-60%, the content of the nacreous powders is 30%-60%, other active additive agents include one or two or three of biological activity glass, S-hydroxyapatite, beta-tricalcium phosphate and sodium borates, and the other active additive agents include 0-15% of the biological activity glass, 0-15% of the S-hydroxyapatite, 0-15% of the beta-tricalcium phosphate and 0-2% of the sodium borates. The toothpaste for repairing the damaged tooth has the advantages that the defects in prior art are overcome, the toothpaste is multifunctional, the storage is stable, and the damaged tooth can be effectively repaired.
Description
Technical field:
The present invention relates to the small stores field, specifically is a kind of toothpaste of repairing injury of teeth.
Background technology:
Human tooth can only secondary teeth, and is at a distance of several years, very of short duration from deciduous teeth to the permanent teeth.Permanent teeth will bear the burden of chewing all one's life, and causing tooth wear because chewing, shortening, occur chase appears in tooth unavoidably, and latent splitting taken place, and crackle reaches dentin depths and dental pulp place, the root of the tooth jackknifing that has.Especially after the middle age, eat reasons such as acidic food, horizontal teeth brushing way be improper because chewing, liking, cause the wedge shaped defect of tooth easily, the dark 1-3mm that has.More than several hard tooth tissue diseases, be the main cause that causes the loss of tooth function, influence daily life.
Toothpaste is developed to the health-care hospital type by the common type that cleans the teeth, and as bioactivity glass toothpaste, strontium chloride tooth paste, antiallergic type toothpaste and all kinds of Chinese herbal toothpaste, but they do not have the effect of repairing injury of teeth.Bioactivity glass toothpaste wherein, as No. 97193085 Chinese patents and No. 200410012897 Chinese patents, though there is the sign of certain reparation injury of teeth at the initial stage, but the part of its reparation is made up of mineral entirely, poor toughness, can not be lasting, the several months will come off at most, can not really receive the effect of repairing injury of teeth.And, bioactivity glass to the repair mechanisms of bone, tooth be by with body fluid in reaction of moisture emit sodium ion, improve pH value, thereby further emit phosphorus, calcium ion, generate hydroxyapatite in bone, tooth deposition, crystallization.And toothpaste time of staying in the oral cavity is very short, and along with toothbrush in the movement that does not stop, if bioactivity glass is active low because the response time is not enough, the purpose that can not utilize the toothpaste dosage form to reach to repair injury of teeth; If adopt active high bioactivity glass, as change its component or reduce its particle diameter, owing to be added with moisture usually in the toothpaste, then active high bioactivity glass will react and approach exhaustion with water when storing.In addition, also having in the toothpaste and add pearl composition, as No. 200410061331 Chinese patents, but only is that pearl composition is used as whitening agent, without any the effect of repairing injury of teeth.
Summary of the invention:
The objective of the invention is does not have the defective of effectively repairing the toothpaste of injury of teeth in order to overcome in the prior art, provide a kind of and have multi-functionally, and stable storage can effectively be repaired the toothpaste of injury of teeth.
The objective of the invention is to realize by following technical proposals:
Its composition of the toothpaste of reparation injury of teeth of the present invention is made up of abrasivus, wetting agent, binding agent, surfactant, sweeting agent, other active additives and aromatic, be 100% in the toothpaste gross weight, the percetage by weight of each component is: abrasivus is 30% ~ 60%, wetting agent is 20% ~ 50%, binding agent is 0.5% ~ 1.5%, and surfactant is 2% ~ 3%, and sweeting agent is 0.1% ~ 0.3%, other active additives 8% ~ 15%, aromatic are 0 ~ 1%; It is characterized in that abrasivus is one or both in Margarita powder, nacre powder, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, silicon dioxide and the aluminium hydroxide, be 100% in the toothpaste gross weight, its consumption percetage by weight is: Margarita powder 30% ~ 60%, nacre powder 30% ~ 60%, calcium carbonate 0 ~ 20%, calcium hydrogen phosphate 0 ~ 20%, calcium pyrophosphate 0 ~ 20%, silicon dioxide 0 ~ 20%, aluminium hydroxide 0 ~ 20%; Other active additives are one or both or three kinds in bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate and the Borax, be 100% in the toothpaste gross weight, its consumption percetage by weight is: bioactivity glass 0 ~ 15%, S-hydroxyapatite 0 ~ 15%, bata-tricalcium phosphate 0 ~ 15%, Borax 0 ~ 2%.
In the such scheme, described wetting agent is one or both in glycerol, sorbitol and the Polyethylene Glycol.
In the such scheme, described binding agent is sodium carboxymethyl cellulose, xanthan gum, chondrus ocellatus Holmes or sodium alginate.
In the such scheme, described surfactant is sodium lauryl sulfate.
In the such scheme, described sweeting agent is saccharin sodium or xylitol.
In the such scheme, described aromatic is pennyroyal spice, citrus spice or Herba Menthae Rotundifoliae material.
In the such scheme, the toothpaste of described reparation injury of teeth has water in the composition, is 100% in the toothpaste gross weight, and its consumption percetage by weight is 0 ~ 35%.
The present invention is a kind of Margarita, nacre toothpaste with dental-filling function, has damaged, the effects such as tooth conceals and splits, odontoseisis, desensitization, anti-inflammation hemostasia, preventing decayed tooth of the neck of repairing portion.Nacre is the nacreous layer in the concha Anodonta seu Cristaria, and the nacre deposition that is both the secretion of pearl culturing clam outer embrane epidermis cell forms, and composition and the clinical efficacy of nacre and Margarita are basic identical.Because Margarita, nacre have organic-inorganic hybrid nanometer flaggy shape structure, calcium carbonate sandwich one layer thickness is several protein layers to tens nano thickness, has very high hardness and tenacity.Contain 16 seed amino acids, vitamin and tens kinds of trace element in the protein layer, calcareous structure and the human body with protein layer that Margarita, nacre have is quite similar.
Add Margarita or nacre in the formulation of tooth-paste of the present invention, bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate and Borax, they have synergism, synergism as cement, sand, reinforcing bar, cytothesis function in conjunction with dentin self, can be rapidly at tooth defect place growing nano flaggy shape crystal, wherein, Margarita or nacre play bonding and toughness reinforcing effect, similar cement, bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate provide mineral, similar sand, Borax plays potentiation, similar reinforcing bar.
Experiment shows that life-time service toothpaste of the present invention is more than three months, and the growth of tooth defect place has the nano-plates layered crystal of 0.2 ~ 1.2mm thickness.Service time is more long, and crystal growth is more thick, with dentin, cementum consubstantiality, and the same white with tooth of color, tough and tensile intensity and tooth zero difference.The crystal repair layer of growth is as the reinforced concrete combination, and existing hardness toughness can not rupture again.Toothpaste stable storage of the present invention is to the human body no side effects.
Therefore, the present invention has overcome the defective of prior art, provides a kind of and has had multi-functionally, and stable storage can effectively be repaired the toothpaste of injury of teeth.
The specific embodiment:
Be described in further detail the present invention below in conjunction with embodiment, but the present invention is not limited only to described embodiment.
Embodiment one
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 30%, sorbitol 20%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, Margarita powder 30%, calcium carbonate 9.4%, bioactivity glass 8%, saccharin sodium 0.1%.
The toothpaste application experiment of the reparation injury of teeth of this example: certain man, 56 years old, the engineer, totally three neck portions are damaged side by side for upper left jaw the one the second premolarss and first molar, are dark type, and the caloric stimulation of chance pain is arranged, the time root of the tooth inflammation arranged.Use toothpaste January, symptom takes a turn for the better 70%, symptom takes a turn for the better after March, pain reduces 90%, and the nanostructured flaggy shape white mineralising crystal that the damaged place's growth one deck 0.3mm of neck portion is thick uses toothpaste after four months, tooth pain, allergy all disappear, neck portion is damaged, can fully recover after a plurality of months with toothpaste, no longer recurrence.
Embodiment two
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 6%, bioactivity glass 6%, S-hydroxyapatite 4%, Borax 1%, pennyroyal spice 1%, saccharin sodium 0.3%, deionized water 28.7%.
The toothpaste application experiment of the reparation injury of teeth of this example: certain man, 70 years old, the doctor, totally two of first, second premolarss of upper right jaw all have neck portion deficient, the caloric stimulation pain are arranged, masticatory atonia.After 2 months, pain reduces 95% with toothpaste, had normal mastication.After 5 months, the flaggy shape white mineralising crystal that the damaged place's growth one deck 0.5mm of neck portion is thick is eaten any caloric stimulation not bitterly, and is chewed hard food oil Deep-fried peanuts, beef with toothpaste.
Embodiment three
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 15%, sorbitol 5%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 3%, nacre powder 30%, bata-tricalcium phosphate 4.7%, bioactivity glass 4.7%, Borax 1.5%, saccharin sodium 0.1%, deionized water 35%.
The toothpaste application experiment of the reparation injury of teeth of this example: certain woman, 55 years old, accounting, upper left jaw second premolars and first molar all are that neck portion is damaged, for dark type, near dental pulp, also have odentoschim, caloric stimulation pain, tip of a root inflammation sometimes.Behind 2 first quarter moons of toothpaste, the nanostructured flaggy shape white mineralising crystal that the damaged place's growth one deck 0.3mm of neck portion is thick, the pain of tooth has disappeared.Continue to use toothpaste, damaged place crystal constantly thickens again, and symptom no longer recurs.
Embodiment four
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 2%, Margarita powder 30%, calcium carbonate 8%, bioactivity glass 8%, Borax 2%, Herba Menthae Rotundifoliae essence 1%, saccharin sodium 0.2%, deionized water 27.8%.
Embodiment five
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 28.3%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, Margarita powder 60%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment six
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 28.3%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 60%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment seven
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 33.3%, Polyethylene Glycol 5%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 20%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment eight
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 33.3%, sorbitol 5%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium hydrogen phosphate 20%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment nine
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 33.3%, sorbitol 5%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium pyrophosphate 20%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment ten
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 33.3%, sorbitol 5%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, silicon dioxide 20%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment 11
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 33.3%, sorbitol 5%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, aluminium hydroxide 20%, bioactivity glass 8%, Borax 1%, saccharin sodium 0.2%.
Embodiment 12
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 34.3%, sorbitol 8%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 10%, bioactivity glass 15%, saccharin sodium 0.2%.
Embodiment 13
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 34.3%, sorbitol 8%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 10%, S-hydroxyapatite 15%, saccharin sodium 0.2%.
Embodiment 14
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 34.3%, sorbitol 8%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 10%, bata-tricalcium phosphate 15%, xylitol 0.2%.
Embodiment 15
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, xanthan gum 1.5%, sodium lauryl sulfate 2%, nacre powder 40%, calcium carbonate 6%, bioactivity glass 6%, S-hydroxyapatite 4%, Borax 1%, citrus spice 1%, saccharin sodium 0.3%, deionized water 18.2%.
Embodiment 16
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, chondrus ocellatus Holmes 1.5%, sodium lauryl sulfate 2%, Margarita powder 40%, calcium hydrogen phosphate 6%, bioactivity glass 6%, S-hydroxyapatite 4%, Borax 1%, pennyroyal spice 1%, saccharin sodium 0.3%, deionized water 18.2%.
Embodiment 17
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium alginate 1%, sodium lauryl sulfate 2%, nacre powder 30%, calcium pyrophosphate 6%, bioactivity glass 6%, bata-tricalcium phosphate 6%, Borax 1%, citrus spice 1%, saccharin sodium 0.2%, deionized water 26.8%.
Embodiment 18
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium alginate 1%, sodium lauryl sulfate 2%, nacre powder 30%, silicon dioxide 6%, bioactivity glass 6%, bata-tricalcium phosphate 6%, Borax 1%, citrus spice 1%, saccharin sodium 0.2%, deionized water 26.8%.
Embodiment 19
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium alginate 1%, sodium lauryl sulfate 2%, nacre powder 30%, aluminium hydroxide 6%, bioactivity glass 6%, bata-tricalcium phosphate 6%, Borax 1%, citrus spice 1%, saccharin sodium 0.2%, deionized water 26.8%.
Embodiment 20
The toothpaste of the reparation injury of teeth of this example is formed (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium alginate 1%, sodium lauryl sulfate 2%, nacre powder 30%, calcium carbonate 6%, S-hydroxyapatite 8%, bata-tricalcium phosphate 6%, Borax 1%, pennyroyal spice 1%, saccharin sodium 0.2%, deionized water 24.8%.
Claims (7)
1.
A kind of toothpaste of repairing injury of teeth, its composition is made up of abrasivus, wetting agent, binding agent, surfactant, sweeting agent, other active additives and aromatic, be 100% in the toothpaste gross weight, the percetage by weight of each component is: abrasivus is 30% ~ 60%, and wetting agent is 20% ~ 50%, and binding agent is 0.5% ~ 1.5%, surfactant is 2% ~ 3%, sweeting agent is 0.1% ~ 0.3%, and other active additives 8% ~ 15%, aromatic are 0 ~ 1%; It is characterized in that abrasivus is a kind of in Margarita powder or the nacre powder, or add a kind of in calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, silicon dioxide and the aluminium hydroxide, be 100% in the toothpaste gross weight, its consumption percetage by weight is: Margarita powder 30% ~ 60%, nacre powder 30% ~ 60%, calcium carbonate 0 ~ 20%, calcium hydrogen phosphate 0 ~ 20%, calcium pyrophosphate 0 ~ 20%, silicon dioxide 0 ~ 20%, aluminium hydroxide 0 ~ 20%; Other active additives are one or both or three kinds in bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate and the Borax, be 100% in the toothpaste gross weight, its consumption percetage by weight is: bioactivity glass 0 ~ 15%, S-hydroxyapatite 0 ~ 15%, bata-tricalcium phosphate 0 ~ 15%, Borax 0 ~ 2%.
2.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that described wetting agent is one or both in glycerol, sorbitol and the Polyethylene Glycol.
3.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that described binding agent is sodium carboxymethyl cellulose, xanthan gum, chondrus ocellatus Holmes or sodium alginate.
4.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that described surfactant is sodium lauryl sulfate.
5.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that described sweeting agent is saccharin sodium or xylitol.
6.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that described aromatic is pennyroyal spice, citrus spice or Herba Menthae Rotundifoliae material.
7.
The toothpaste of reparation injury of teeth according to claim 1 is characterized in that in the described toothpaste component water being arranged, and is 100% in the toothpaste gross weight, and its consumption percetage by weight is 0 ~ 35%.
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| CN 201210403877 CN102860973B (en) | 2012-10-22 | 2012-10-22 | Toothpaste for repairing damaged tooth |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104013539A (en) * | 2014-03-20 | 2014-09-03 | 胡方 | Preparation method of bone repair toothpaste agent inducing gene expression |
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| CN104013993B (en) * | 2014-03-20 | 2015-10-07 | 胡方 | A kind of preparation method with the bone biological restoration preparation of inducible gene expression |
| CN104083309A (en) * | 2014-03-26 | 2014-10-08 | 邢建国 | Chinese medicinal toothpaste with yin nourishing, kidney tonifying, tooth strengthening, bactericidal, anti-inflammatory, analgesic and astringent effects |
| CN104800139A (en) * | 2015-03-02 | 2015-07-29 | 兰柳生 | Whitening toothpaste |
| CN105125587B (en) * | 2015-09-25 | 2019-02-22 | 北京刷新活力健康科技有限公司 | A kind of permanent tooth brilliant white multiple-effect dental care object and its application |
| CN105477019B (en) * | 2015-11-23 | 2019-08-30 | 北京刷新活力健康科技有限公司 | A kind of bioactive minerals powder oral health effervescent tablet and the preparation method and application thereof |
| CN107235634A (en) * | 2017-07-06 | 2017-10-10 | 江西草珊瑚口腔护理用品有限公司 | A kind of biological activated glass ceramic material and preparation method thereof and a kind of toothpaste |
| CN108403453A (en) * | 2018-05-29 | 2018-08-17 | 中国科学院化学研究所 | A kind of toothpaste containing phosphosilicate glass |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1743027A (en) * | 2004-09-02 | 2006-03-08 | 深圳市清华源兴生物医药科技有限公司 | Silver-contained oral-cavity cleaning article |
| CN101259161B (en) * | 2007-03-08 | 2011-06-22 | 宁波立华制药有限公司 | Production technology of cream for treating toothache and odontitis |
| US20090324516A1 (en) * | 2008-06-27 | 2009-12-31 | Muscle Dave P | Composition and Method for Enhancing Flouride Uptake Using Bioactive Glass |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013539A (en) * | 2014-03-20 | 2014-09-03 | 胡方 | Preparation method of bone repair toothpaste agent inducing gene expression |
| CN104013539B (en) * | 2014-03-20 | 2016-07-06 | 胡方 | A kind of preparation method of the Bone Defect Repari toothpaste unguentum with inducible gene expression |
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