CN103006529B - Toothpaste capable of stopping infection of decayed tooth - Google Patents
Toothpaste capable of stopping infection of decayed tooth Download PDFInfo
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- CN103006529B CN103006529B CN201210561547XA CN201210561547A CN103006529B CN 103006529 B CN103006529 B CN 103006529B CN 201210561547X A CN201210561547X A CN 201210561547XA CN 201210561547 A CN201210561547 A CN 201210561547A CN 103006529 B CN103006529 B CN 103006529B
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Abstract
The invention relates to toothpaste, which belongs to the field of daily necessities and is capable of stopping infection of a decayed tooth. The toothpaste is composed of abrasive, humectant, adhesive, surfactant, sweetening agent, other active additives, aromatic and water, and is characterized in that other active additives are powdered otolithum sciaenae, calcined native copper, magnesium sulfate, zinc oxide, calcined scale calcium, bioactive glass, S- hydroxyapatite, Beta-tricalcium phosphate and sodium borate. By taking the total weight of the toothpaste as 100%, the weight percent of the components are as follows: 7%-24% of powdered otolithum sciaenae, 0.3%-1% of calcined native copper, 1%-1.5% of magnesium sulfate, 1%-3% of zinc oxide, 0-10% of calcined scale calcium, 0-8% of bioactive glass, 0-6% of S-hydroxyapatite, 0-12% of Beta-tricalcium phosphate and 0-1% of sodium borate. The toothpaste provided by the invention has inflammation reduction, repair and analgesic effects to decayed teeth of 2 to 3 degrees, is stable in storage, can mineralize the decayed teeth of 2 to 3 degrees to be in rest state and can efficiently prevent the decayed teeth from worsening to 4-5 degrees.
Description
Technical field:
The present invention relates to the small stores field, specifically a kind of toothpaste that stops the dental caries pathological changes.
Background technology:
Existing much curative effect-type toothpaste on the market at present: hemostasis, antiallergic, preventing decayed tooth, repairing dental enamel dental caries, and the toothpaste such as enamel fissure.But they all do not have 2,3 degree dental caries is antiinflammatory, reparation, the analgesic effect of carious dentin, do not make 2,3 degree dental caries mineralisings become the pathological changes resting state, effectively stop the function of dental caries to 4,5 degree dental caries development.
Summary of the invention:
The objective of the invention is not make 2,3 degree dental caries mineralisings become the pathological changes resting state in order to overcome in prior art, effectively stop the defect of dental caries to the toothpaste of 4,5 degree dental caries development, a kind of antiinflammatory, reparation, analgesic effect had 2,3 degree dental caries is provided, stable storage, can make 2,3 degree dental caries mineralisings become the pathological changes resting state, be arrested caries, effectively stop the toothpaste of dental caries to 4,5 degree dental caries development.
The objective of the invention is to realize by following technical proposals:
Its component of toothpaste of termination dental caries pathological changes of the present invention is abrasivus, wetting agent, binding agent, surfactant, sweeting agent, other active additives, aromatic and water, the toothpaste gross weight of take is 100%, the percetage by weight of each component is: abrasivus is 7% ~ 27%, wetting agent is 20% ~ 30%, and binding agent is 0.5% ~ 1.5%, and surfactant is 1.5% ~ 2%, sweeting agent is 0.1% ~ 0.3%, other active additives 22% ~ 45%, aromatic are 0.2% ~ 1.5%, water 25% ~ 30%; It is characterized in that other active additives are Asteriscus Pseudosciaenae powder, Pyritum (calcined), magnesium sulfate, zinc oxide, forge fish scale calcium, bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate and Borax, the toothpaste gross weight of take is 100%, its consumption percetage by weight is: Asteriscus Pseudosciaenae powder 7% ~ 24%, Pyritum (calcined) 0.3% ~ 1%, magnesium sulfate 1% ~ 1.5%, zinc oxide 1% ~ 3%, forge fish scale calcium 0 ~ 10%, bioactivity glass 0 ~ 8%, S-hydroxyapatite 0 ~ 6%, bata-tricalcium phosphate 0 ~ 12%, Borax 0 ~ 1%.
In such scheme, described abrasivus is one or both in Margarita powder, nacre powder, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, silicon dioxide and aluminium hydroxide.
In such scheme, described wetting agent is one or both in glycerol, sorbitol and Polyethylene Glycol.
In such scheme, described binding agent is sodium carboxymethyl cellulose, xanthan gum, chondrus ocellatus Holmes or sodium alginate.
In such scheme, described surfactant is sodium lauryl sulfate.
In such scheme, described sweeting agent is saccharin sodium or xylitol.
In such scheme, described aromatic is one or both in eugenol, pennyroyal spice, citrus spice and Herba Menthae Rotundifoliae material.
The present invention is added with the Chinese medicines such as Asteriscus Pseudosciaenae, fish scale, Pyritum, Margarita in toothpaste, in the books such as " Practical Chinese medicinal dictionary " " Chinese medicine voluminous dictionary " of ancient medical book " Kaibao Bencao " Compendium of Material Medica " the medical center bun is wanted " " detailed outline is picked up any lost article from the road " and publication in modern age, the medical value of Asteriscus Pseudosciaenae, fish scale, Pyritum, Margarita powder is discussed.
Asteriscus Pseudosciaenae: sweet in the mouth, property are salty, nontoxic, and fossil is treating stranguria, detumescence, for stranguria caused by urinary stone, dysuria, otalgia suppurate, rhinitis, sinusitis with purulent discharge.Pulverizing is used.
Fish scale: sweet in the mouth, salty, flat, nontoxic, hemostasis, anal fistula, treatment skin ulcer, innominate toxic swelling, tonifying the kidney to consolidate the essence, leukemia.Forge use.
Pyritum: nature and flavor, suffering, flat, nontoxic, function cures mainly: dissipating blood stasis, synthetism, pain relieving, for tumbling and swelling, injured bone, forge use.Pyritum (calcined) is called again the vinegar Pyritum.
Margarita: nature and flavor, sweet, salty, cold, nontoxic, tranquilizing mind, yin nourishing relieve dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, removing toxic substances and promoting granulation, control that palpitation with fear, swollen, epilepsy seized with terror, infantile convulsion are twitched, dysphoria with smothery sensation is quenched one's thirst, sore throat, aphtha, order life cataracta, skin infection do not close up for a long time.Pulverizing is used.
Modern medicine research shows in Asteriscus Pseudosciaenae, Margarita and contains aminoacid that a large amount of human bodies can not synthesize and the somatomedin (Asteriscus Pseudosciaenae, Margarita, bone, tooth are all the biomineralization product) of bone, and four to form essence very close.Its biomineralization product is all to be subjected to its contained amino acid regulating and controlling, in toothpaste, adds the Chinese medicines such as Asteriscus Pseudosciaenae, fish scale, Pyritum, Margarita to suppressing 2,3 degree dental caries to 4,5 degree dental caries development, and kills the dental caries bacterium, and antiinflammatory, pain relieving, reparation dentin play a crucial role.
Toothpaste of the present invention is to the dental caries pain symptom, but as because eating supercool overheated diet ache, pain that dental caries causes because of the cold tooth cavity of food embedding, kowtowing the equal pain relievings such as pain, spontaneous pain, dark wedge-shaped defect pain.Can repair simultaneously cementum and absorb, remove odontoseisis, repair darker tooth fine fisssure, recover masticatory function.Experiment shows, after toothpaste of the present invention is used 6 months, can make the interior soft dentin of 2,3 degree cavities in a tooth repair into the dentin of hard crystallization light, the dental caries bacterial plaque can not be assembled, and becomes the arrested caries dummy, no longer pain, effectively stop dental caries to the serious dental caries development of 4,5 degree (referring to suffer from tooth for residual crown, undesirable root, easily fall tooth), reach and do not lose tooth, keep dermal tooth, extend tooth service life more than 10 years or 20 years.Toothpaste of the present invention is to the human body no side effects.
Therefore, the present invention has overcome the defect of prior art, and the toothpaste provided has 2,3 degree dental caries antiinflammatory, reparation, analgesic effect, stable storage, can make 2,3 degree mineralization of decayed tooth become the pathological changes resting state, namely arrested caries, effectively stop dental caries to 4,5 degree dental caries development.Even if 5 degree dental caries, also can mineralising become arrested caries.
The specific embodiment:
Below in conjunction with embodiment, be described in further detail the present invention, but the present invention is not limited only to described embodiment.
Embodiment mono-
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 1.8%, Margarita powder 7%, Asteriscus Pseudosciaenae powder 20%, forge fish scale calcium 10%, calcium carbonate 7%, magnesium sulfate 1%, zinc oxide 2%, Pyritum (calcined) 0.5%, Borax 1%, eugenol 0.3%, pennyroyal spice 1.2%, saccharin sodium 0.2%, deionized water 27.1%.
The toothpaste application experiment of the termination dental caries pathological changes of this example: certain female, the east office worker of business office of large subbranch of Chengdu industrial and commercial bank, 35 years old, on 3 years front lefts, ranked first the nearly lingual surface of grinding one's teeth in sleep circular cavity is arranged, be 3 degree dental caries, feel to eat supercool overheated food and ache, pain during the food impaction tooth cavity.The large shape in the young end of cavity, through with after 3, this toothpaste, ache and obviously reduce, pain reduces, and uses 6 afterwards namely 6 months the time when toothpaste, eats cold and hot diet and does not ache, food impaction tooth cavity imperception, can pain yet, by probe, to detect and suffer from tooth without pain in 7.5 months, surface forms the mineralising reparative dentin, quality is hard, smooth, light, formed the arrested caries mineralized layer.By 2 years, follow the trail of to pay a return visit and know that dental caries does not recur.2,3 degree dental caries are stopped to 4,5 degree dental caries development.
Embodiment bis-
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 1.8%, nanometer Margarita powder 20%, Asteriscus Pseudosciaenae powder 7%, forge fish scale calcium 10%, calcium hydrogen phosphate 7%, magnesium sulfate 1.5%, zinc oxide 3%, Pyritum (calcined) 0.5%, eugenol 0.2%, citrus spice 1%, saccharin sodium 0.2%, deionized water 26.8%.
The toothpaste application experiment of the termination dental caries pathological changes of this example: certain man, 40 years old, the Chengdu aluminum alloy doors and windows were decorated the sales manager of factory, and upper left row's wisdom teeth jaw closes face darker cavity, and 3 degree dental caries, have and ache, pain during the cold tooth cavity of food embedding, dental caries suffer from 3 years.After with 3, this toothpaste, being 3 months, the disappearance of aching, pain symptom obviously reduces.It is, after 6 months, to eat cold and hot diet and do not ache that toothpaste is used 6, and food is rare caulked tooth cavity also, even the caulked tooth cavity is gargled with tea namely tear-away, can not produce pain.Use toothpaste after 8 months, detect and suffer from tooth without pain through probe, the dental caries surface forms the mineralising reparative dentin, and former softening dentin crystallizes into the hard light of quality, forms the arrested caries mineralized layer.Do not have bacterial plaque to assemble, 3 degree dental caries are stopped to 4,5 degree dental caries development, by 2 years, follow the trail of to pay a return visit and know that dental caries does not recur.
Embodiment tri-
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 15%, sorbitol 5%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 1.8%, Asteriscus Pseudosciaenae powder 24%, bata-tricalcium phosphate 8%, S-hydroxyapatite 6%, calcium hydrogen phosphate 7%, magnesium sulfate 1%, zinc oxide 2%, Pyritum (calcined) 0.5%, pennyroyal spice 1.1%, saccharin sodium 0.2%, deionized water 27.4%.
The toothpaste application experiment of the termination dental caries pathological changes of this example: certain female, 53 years old, Chengdu the 3rd project manager of construction engineering corporation, found before 3 years that upper right ranked second that front tooth lip side is upper outside a duck eye, 2-3 degree dental caries, feel to breathe out the cold wind tooth and ache, eat also pain of Superheat Food, through with this toothpaste, being three months, drink the minimizing of aching of cold and hot diet, breathe out cold wind pain and obviously reduce, toothpaste with 6 namely 6 months, ache, pain disappears entirely.Use toothpaste after 7 months, detect and suffer from tooth without pain through probe, the dental caries surface has formed the mineralising reparative dentin, and former softening dentin crystallizes into the arrested caries mineralized layer of the hard light of quality.Do not have bacterial plaque to assemble, 2,3 degree dental caries are stopped to 4,5 degree dental caries development, by 2 years, follow the trail of to pay a return visit and know that dental caries does not recur.
Embodiment tetra-
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 15%, sorbitol 5%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 1.8%, nacre powder 18%, Asteriscus Pseudosciaenae powder 8%, bata-tricalcium phosphate 12%, calcium carbonate 7%, magnesium sulfate 1.5%, zinc oxide 1%, Pyritum (calcined) 1%, eugenol 0.3%, pennyroyal spice 1%, saccharin sodium 0.2%, deionized water 27.2%.
The toothpaste application experiment of the termination dental caries pathological changes of this example: certain man, 68 years old, the peace engineer of fire engineering company in Chengdu, lower-left ranked second premolars and before 4 years, found that the lingual surface cervical region has a linear cavity, the sensation odontoseisis, masticatory atonia, have pain.Through using this toothpaste after 3 March, had normal mastication, odontoseisis takes a turn for the better, and pain reduces, and toothpaste is 6 months with 6, and odontoseisis, pain symptom have disappeared entirely.Use toothpaste after 7 months, detect and suffer from tooth without pain through probe, the dental caries surface has formed the mineralising reparative dentin, and former softening dentin crystallizes into the arrested caries mineralized layer of the hard light of quality.Do not have bacterial plaque to assemble, more can be to 4,5 degree dental caries development.
Embodiment five
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, sodium carboxymethyl cellulose 1%, sodium lauryl sulfate 1.8%, Margarita powder 12%, Asteriscus Pseudosciaenae powder 12%, forge fish scale calcium 7%, calcium hydrogen phosphate 7%, bioactivity glass 8%, magnesium sulfate 1%, zinc oxide 1%, Pyritum (calcined) 0.3%, Herba Menthae Rotundifoliae material 1%, saccharin sodium 0.2%, deionized water 27.7%.
Embodiment six
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 30%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 2%, nacre powder 15%, Asteriscus Pseudosciaenae powder 10%, forge fish scale calcium 7%, calcium pyrophosphate 7.5%, magnesium sulfate 1%, zinc oxide 1%, Pyritum (calcined) 0.3%, eugenol 0.3%, pennyroyal spice 0.2%, saccharin sodium 0.2%, deionized water 25%.
Embodiment seven
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 20%, Polyethylene Glycol 5%, sodium carboxymethyl cellulose 1.5%, sodium lauryl sulfate 1.5%, nacre powder 10%, silicon dioxide 9.2%, Asteriscus Pseudosciaenae powder 10%, forge fish scale calcium 10%, magnesium sulfate 1%, zinc oxide 1%, Pyritum (calcined) 0.5%, pennyroyal spice 0.2%, saccharin sodium 0.1%, deionized water 30%.
Embodiment eight
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 20%, sodium carboxymethyl cellulose 0.5%, sodium lauryl sulfate 1.5%, nacre powder 10%, aluminium hydroxide 5%, Asteriscus Pseudosciaenae powder 20%, forge fish scale calcium 10%, magnesium sulfate 1.5%, zinc oxide 3%, Pyritum (calcined) 0.5%, eugenol 0.3%, xylitol 0.3%, deionized water 27.4%.
Embodiment nine
Glycerol 10%, sorbitol 10%, sodium alginate 0.5%, sodium lauryl sulfate 1.5%, Margarita powder 7.7%, Asteriscus Pseudosciaenae powder 20%, forge fish scale calcium 8%, bata-tricalcium phosphate 12%, magnesium sulfate 1.5%, zinc oxide 3%, Pyritum (calcined) 0.5%, eugenol 0.2%, saccharin sodium 0.1%, deionized water 25%.
Embodiment ten
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, xanthan gum 1%, sodium lauryl sulfate 1.8%, nacre powder 10%, calcium carbonate 5%, Asteriscus Pseudosciaenae powder 15%, forge fish scale calcium 10%, magnesium sulfate 1.5%, zinc oxide 3%, bioactivity glass 5%, Pyritum (calcined) 0.5%, eugenol 0.1%, pennyroyal spice 1%, saccharin sodium 0.2%, deionized water 25.9%.
Embodiment 11
The toothpaste of the termination dental caries pathological changes of this example forms (percetage by weight) by following component:
Glycerol 10%, sorbitol 10%, chondrus ocellatus Holmes 1%, sodium lauryl sulfate 1.8%, Margarita powder 10%, calcium carbonate 5%, Asteriscus Pseudosciaenae powder 20%, forge fish scale calcium 10%, magnesium sulfate 1%, zinc oxide 3%, Pyritum (calcined) 0.5%, eugenol 0.1%, pennyroyal spice 1%, saccharin sodium 0.2%, deionized water 26.4%.
The present invention stops the toothpaste of dental caries pathological changes and follows up a case by regular visits to through tracking, 2-3 degree dental caries example 58 examples wherein, general use ache sx↓ or disappearance in 3-4 month, 7-8 menstruation probe detected and suffered from tooth without pain, and the dental caries surface has formed the mineralising reparative dentin, and former softening dentin crystallizes into the arrested caries mineralized layer of the hard light of quality, do not have bacterial plaque to assemble, effectively stop to 4,5 degree dental caries development, comprehensive effective percentage reaches more than 95%, and wherein embodiment 1-4 is typical case.
Claims (7)
1. toothpaste that stops the dental caries pathological changes, its component is abrasivus, wetting agent, binding agent, surfactant, sweeting agent, other active additives, aromatic and water, the toothpaste gross weight of take is 100%, and the percetage by weight of each component is: abrasivus is 7% ~ 27%, and wetting agent is 20% ~ 30%, binding agent is 0.5% ~ 1.5%, surfactant is 1.5% ~ 2%, and sweeting agent is 0.1% ~ 0.3%, other active additives 22% ~ 45%, aromatic is 0.2% ~ 1.5%, water 25% ~ 30%; It is characterized in that other active additives are Asteriscus Pseudosciaenae powder, Pyritum (calcined), magnesium sulfate, zinc oxide, forge fish scale calcium, bioactivity glass, S-hydroxyapatite, bata-tricalcium phosphate and Borax, the toothpaste gross weight of take is 100%, its consumption percetage by weight is: Asteriscus Pseudosciaenae powder 7% ~ 24%, Pyritum (calcined) 0.3% ~ 1%, magnesium sulfate 1% ~ 1.5%, zinc oxide 1% ~ 3%, forge fish scale calcium 0 ~ 10%, bioactivity glass 0 ~ 8%, S-hydroxyapatite 0 ~ 6%, bata-tricalcium phosphate 0 ~ 12%, Borax 0 ~ 1%.
2. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described abrasivus is one or both in nacre powder, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, silicon dioxide and aluminium hydroxide.
3. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described wetting agent is one or both in glycerol, sorbitol and Polyethylene Glycol.
4. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described binding agent is sodium carboxymethyl cellulose, xanthan gum or sodium alginate.
5. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described surfactant is sodium lauryl sulfate.
6. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described sweeting agent is saccharin sodium or xylitol.
7. the toothpaste of termination dental caries pathological changes according to claim 1, is characterized in that described aromatic is one or both in eugenol, pennyroyal spice, citrus spice and Herba Menthae Rotundifoliae material.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210561547XA CN103006529B (en) | 2012-12-22 | 2012-12-22 | Toothpaste capable of stopping infection of decayed tooth |
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| CN201210561547XA CN103006529B (en) | 2012-12-22 | 2012-12-22 | Toothpaste capable of stopping infection of decayed tooth |
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| CN103006529B true CN103006529B (en) | 2013-11-27 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US11826447B2 (en) | 2016-05-10 | 2023-11-28 | Colgate-Palmolive Company | Alginate dentifrice compositions and methods of making thereof |
| CN107049828A (en) * | 2017-06-22 | 2017-08-18 | 缪来耿 | A kind of anti-caries toothpaste and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196234A (en) * | 1998-03-19 | 1998-10-21 | 王素艳 | Aloes active toothpaste and producing technology thereof |
| CN1899261A (en) * | 2006-07-26 | 2007-01-24 | 广州立白企业集团有限公司 | Composition and its use in oral nursing |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196234A (en) * | 1998-03-19 | 1998-10-21 | 王素艳 | Aloes active toothpaste and producing technology thereof |
| CN1899261A (en) * | 2006-07-26 | 2007-01-24 | 广州立白企业集团有限公司 | Composition and its use in oral nursing |
Non-Patent Citations (1)
| Title |
|---|
| 赵婷，高昂，巩江，程亮，李娜，王明，张新刚，曹梦晔，倪士峰.《鱼脑石药学研究概况》.《辽宁中医药大学学报》.2011,第13卷(第9期),第82-84页. * |
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