CN102860460B - Coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects and production method thereof - Google Patents
Coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects and production method thereof Download PDFInfo
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Abstract
The invention discloses coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects, which is prepared by the following raw materials by weight: 10-16 parts of corns, 10-16 parts of pearl barley, 8-13 parts of black rice, 8-13 parts of oatmeal, 8-13 parts of black buckwheat, 8-13 parts of polished round-grained rice, 11-15 parts of mung beans, 5-9 parts of pumpkins, 5-9 parts of balsam pears, 5-9 parts of sweet potato, 5-8 parts of medlar, 3-5 parts of fennel and 3-5 parts of spinach roots. According to the coarse cereal, fruit and vegetable food provided by the invention, the diet structure of people with cancer is reasonably adjusted, nutrient substances are replenished, and resitsance of an organism immune system on cancer cells is enhanced.
Description
Technical field
The present invention relates to a kind of functional food, in particular to a kind of coarse cereal fruit vegetable food and method for making thereof with cancer-resisting effect, belong to health food processing technique field.
Background technology
Cancer is common frdquently encountered disease, and people's life and healthy in serious harm, because the position of pathogenesis of cancer is different, can have various cancer, as non-small cell lung cancer, cancer of the stomach, lung cancer, osteocarcinoma, cutaneum carcinoma, intestinal cancer, liver cancer etc.Cancer cell is different from normal structure and cell, not according to Normocellular metabolic rule growth, thereby becomes unfettered and controls, and being irregular ramp, so that can destroy the structure of normal structure organ and affect its function.Cancer cell is compared with normal cell, has the abnormal of structure, function and metabolism, and they have paranormal Reproductive activity, and this hyperplasia and body are not in tune.Pernicious cancer cell can infiltrate and spread towards periphery, and even diffusion transfer, to other organ, continues to increase exponentially, causes human body or life are endangered greatly.
Due to the cancer factor and endocrine variation; cancer patient usually has appetite decline, the sense of taste changes; the metabolic mechanism of each large nutriment of body interior all changes; occur Body weight loss and nutrient depletion, and nutrition exhaustion is so that occur that the cachexia of cancer is patient's the basic cause of death thereupon.In addition, the various treatment means for cancer that adopt at present, as radiotherapy, chemotherapy, operation etc., be another test to cancer patient's sick body, such as chemotherapy, likely cause strong digestive tract reaction, patient is perplexed by serious nauseating, vomiting in chemotherapy stage, almost can not take food.Even some embolic chemotherapy can directly cause that nutriment runs off at kidney and enteron aisle, causes patient's nutrition famine.According to foreign data, show that ， hospital accepts the patient of radiotherapy, chemotherapy, nearly 20%-40% dies from severe malnutrition.As can be seen here, cancer patient is very important in the nutritional support of radiotherapy or chemotherapeutic period.
Coarse cereals refer to other grains except rice and wheat, are the general names of essay kind cereal, essay kind beans and potato class; Mainly contain buckwheat, oat, barley, formal little slender bamboo wheat, rotten broomcorn millet, millet, corn, waxy corn, broad bean, pea, mung bean, black soya bean, kidney bean, red bean etc.China Shi Yige large agricultural country, coarse cereals resource is very abundant, is maximum in the world " coarse cereals kingdom ".Coarse cereals plantation is with a long history, various in style, widely distributed.According to statistics, the 2nd, the area of 2002 Nian， China buckwheats, rotten broomcorn millet and the output Yi Ju world, yield of broad bean accounts for 1/2 of Gross World Product, and mung bean, red bean output account for 1/3 of Gross World Product, are the main product states of oat, cowpea, French beans.Coarse cereals are generally acknowledged pollution-free natural pollution-free foods, have special food treatment of food therapy effect, in modern safety health food, have critical role.The rational proportion that the nutritional labelings such as the protein in coarse cereals, fat, carbohydrate, vitamin, mineral matter, cellulose meet that human body takes in, has abundant nutritive value.Traditional Chinese Medicine is thought " plain tea and simple food, good for health ".Huangdi's Internal Classics is pointed out: " supporting vital QI with five kinds of grains, assisting vital QI with five kinds of fruits, reinforcing vital QI with meats of five livestock, supplementing vital QI with five kinds of veg etables, taking the mixed foods of various natures and flavors, with replenishing vital essence and invigorating vital QI." think that diet will accomplish comprehensive supply of healthy desired nutritional, could body building, promote longevity.
Because coarse cereals are generally acknowledged pollution-free natural pollution-free foods, there is special food treatment of food therapy effect, therefore by experimental study, develop a kind of coarse cereal fruit vegetable food with cancer-resisting effect, this seems necessary.
Summary of the invention
The object of the invention is to by various coarse cereals, fruits and vegetables and consumption are screened and prescription, a kind of coarse cereal fruit vegetable food and method for making thereof with cancer-resisting effect is provided.Unexpectedly, coarse cereal fruit vegetable food of the present invention can not only reach the object of reasonable adjustment cancer patient dietary structure, and in extra-nutrition material, strengthened the resistance of body immune system to cancer cell, both can be used as cancer patient's nutritional health food, also can be by often eating the object that reaches pre-anti-cancer.
First bright object of this law is achieved in that
A coarse cereal fruit vegetable food for cancer-resisting effect, is prepared from by the raw material that comprises following ratio of weight and number: corn 10-16 part, seed of Job's tears 10-16 part, black rice 8-13 part, oatmeal 8-13 part, black buckwheat 8-13 part, polished rice 8-13 part, mung bean 11-15 part, pumpkin 5-9 part, balsam pear 5-9 part, Ipomoea batatas 5-9 part, matrimony vine 5-8 part, fennel seeds 3-5 part, Radix spinach 3-5 part.
Second object of the present invention is test like this:
A method for making for above-mentioned coarse cereal fruit vegetable food, comprises the steps:
(1) be soaked in 12-20min in 20-30 ℃ of water after getting respectively the decortication of corn, black buckwheat, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, pulverize, cross 60-80 mesh sieve, standby;
(2) get the seed of Job's tears, remove cot, put in preheating frying container, with slow fire heating, fry to surperficial micro-yellow, slightly heave, during tool fragrance, take out and pulverize, cross 60-80 mesh sieve, standby;
(3) get respectively black rice, oatmeal, polished rice and be soaked in 12-20min in 20-30 ℃ of water, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, 145-160 ℃ of frying 10-20min, microwave bulking 5-10min, pulverizes, and crosses 60-80 mesh sieve, standby;
(4) get mung bean, be soaked in 20-40min in 35-45 ℃ of water, after taking-up, put into boiling water and boil 15-20min, well-done mung bean is drained away the water, be placed in steamer and cook 10-15min to the thorough slaking of mung bean, then send in dryer, with the 80-100 ℃ of dry 2-4h that dries, to mung bean moisture be 5%-7%, pulverized 60-80 mesh sieve, standby;
(5) get pumpkin respectively, sweet potato washing is clean, peeling stripping and slicing, put into water and soak 25-30min, then at-30 ℃, carry out quick-frozen vacuum drying, the quick-frozen time is 1.5-2h, when vacuum reaches 5Pa, takes out, and pulverizes 60-80 mesh sieve, standby;
(6) getting balsam pear cleans, dry, section, every thickness is 0.1～0.2 centimetre, under the sunlight of 20 ℃～30 ℃ of temperature, shines 2～3 hours, make balsam pear contained humidity be removed 10%～20%, balsam pear slice after Exposure to Sunlight is put into dryer, with the 80-90 ℃ of dry 5-9h that dries, to balsam pear contained humidity be lower than 5%, pulverized 60-80 mesh sieve, standby;
(7) get respectively matrimony vine, fennel seeds, Radix spinach, the baking oven inner drying 15-30min of 90-100 ℃, pulverized 60-80 mesh sieve, standby;
(8) material powder after above-mentioned processing is mixed, be directly prepared into coarse cereal fruit vegetable food; Or the material powder after above-mentioned processing is mixed, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food after thickener.
Preferably, the method for making of above-mentioned coarse cereal fruit vegetable food, wherein in step (3), the power of microwave bulking is 1500-2000W.
Compared with prior art, the coarse cereal fruit vegetable food the present invention relates to can not only reach the object of reasonable adjustment cancer patient dietary structure, and in extra-nutrition material, strengthened the resistance of body immune system to cancer cell, both can be used as cancer patient's nutritional health food, also can be by often eating the object that reaches pre-anti-cancer.Table 1 by effect test example can be found out, compare with control group, test group all has significant difference to the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, especially compare with model control group, the present invention raise with coarse cereal fruit vegetable feeding experiment group aspect the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, have utmost point significant difference (
p< 0.01), with the positive controls of basal feed, compare and there is significant difference with raising (
p< 0.05).This is indicating that coarse cereal fruit vegetable food of the present invention can fiting chemical treatment reach anticancer function very effectively.
The specific embodiment
Form is described in further detail foregoing of the present invention again by the following examples, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following embodiment, all technology realizing based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1
Composition of raw materials: 15 kilograms of corns, 13.5 kilograms of the seeds of Job's tears, 10.3 kilograms of black rices, 10.2 kilograms of oatmeals, 11 kilograms, black buckwheat, 12.5 kilograms of polished rices, 13.8 kilograms, mung bean, 7.5 kilograms, pumpkin, 6.8 kilograms, balsam pear, 8.2 kilograms, Ipomoea batatas, 6 kilograms of matrimony vines, 4.1 kilograms of fennel seeds, 4 kilograms of Radix spinach.
Processing step:
(1) be soaked in 15min in 20-30 ℃ of water after taking respectively the decortication of corn, black buckwheat, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, pulverize, cross 80 mesh sieves, standby;
(2) take the seed of Job's tears, remove cot, put in preheating frying container, with slow fire heating, fry to surperficial micro-yellow, slightly heave, during tool fragrance, take out and pulverize, cross 80 mesh sieves, standby;
(3) take respectively black rice, oatmeal, polished rice and be soaked in 15min in 20-30 ℃ of water, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, 150 ℃ of left and right frying 10-20min, microwave bulking 8min, pulverizes, and crosses 80 mesh sieves, standby;
(4) take mung bean, be soaked in 30min in 35-45 ℃ of water, after taking-up, put into boiling water and boil 15min, well-done mung bean is drained away the water, be placed in steamer and cook 10-15min to the thorough slaking of mung bean, then send in dryer, with the 80-100 ℃ of dry 2-4h that dries, to mung bean moisture be 5%-7%, pulverized 80 mesh sieves, standby;
(5) take pumpkin respectively, sweet potato washing is clean, peeling stripping and slicing, put into water and soak 25-30min, then at-30 ℃, carry out quick-frozen vacuum drying, the quick-frozen time is 1.5-2h, when vacuum reaches 5Pa, takes out, and pulverizes 80 mesh sieves, standby;
(6) taking balsam pear cleans, dry, section, every thickness is 0.2 centimetre, under the sunlight of 20 ℃～30 ℃ of temperature, shines 2～3 hours, make balsam pear contained humidity be removed 10%～20%, balsam pear slice after Exposure to Sunlight is put into dryer, with 90 ℃ of dry 5-9h that dry, to balsam pear contained humidity be lower than 5%, pulverized 80 mesh sieves, standby;
(7) take respectively matrimony vine, fennel seeds, Radix spinach, the baking oven inner drying 25min of 90-100 ℃, pulverized 80 mesh sieves, standby;
(8) material powder after above-mentioned processing is mixed, be directly prepared into coarse cereal fruit vegetable food, as noodles; Or the material powder after above-mentioned processing is mixed, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food after thickener, as the nutrient breakfast that can reconstitute.
The impact of embodiment 2 coarse cereal fruit vegetable food of the present invention on the growth of people's lung cancer A549 cell transplanted tumor in nude mice
(1) preparation of coarse cereal fruit vegetable feed
Coarse cereal powder composition: the mixed material powder being prepared from according to the composition and engineering of embodiment 1.
Basal feed: commercially available conventional test mouse feed, the content of protein wherein, fat, minerals and vitamins is to guarantee that growing of growing animal is necessary.
Coarse cereal fruit vegetable feed: made by 77.5% basal feed and 22.5% coarse cereal powder by weight percentage.
(2) preparation of people's lung cancer Nude Mouse Model
50 of SPF level BALB/c-nu mouse, 6 week age, body weight l8g-20 g.The lung cancer cell line A549 cell in growth period of taking the logarithm, with aseptic PBS, adjusting A549 cell concentration is 3 * 10
7/ mL, at BALB/c-nu mouse back subcutaneous vaccination A549 cell 0.1ml, treats that subcutaneous transplantation knurl volume reaches 75 mm
3during left and right (about lOd), model manufacturing success.
(3) grouping and administration
By knurl volume and mice with tumor body weight homeostatic principle, be divided into following three groups, 15 every group, and raise with corresponding feed:
Model control group: freely drink water, raise with basal feed.
Positive controls: freely drink water, raise with basal feed, lumbar injection 15mg/kg oxaliplatin simultaneously, the next day administration 1 time, amount to 8 times.
Test group: freely drink water, raise with coarse cereal fruit vegetable feed, lumbar injection 15mg/kg oxaliplatin simultaneously, the next day administration 1 time, amount to 8 times.
After last administration 48 h, mouse is put to death in dislocation, and excision transplantable tumor, takes knurl weight.Heavy inhibiting rate (%) IR=(1-experimental group knurl weight-average value/model control group knurl weight-average value) * 100% of knurl.The medicine that relatively embodies weighing by knurl suppresses the impact of knurl growth on people's lung cancer A549 cell nude mice.
(4) test results and analysis
Result of the test shows (referring to table 1): compare with control group, test group all has significant difference to the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, especially compare with model control group, the present invention raise with coarse cereal fruit vegetable feeding experiment group aspect the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, have utmost point significant difference (
p< 0.01), with the positive controls of basal feed, compare and there is significant difference with raising (
p< 0.05).This is indicating that coarse cereal fruit vegetable food of the present invention can fiting chemical treatment reach anticancer function very effectively.
The impact of table 1 coarse cereal fruit vegetable feed on the growth of people's lung cancer A549 cell transplanted tumor in nude mice
| Group | Knurl weight/mg | Average tumour inhibiting rate/% |
| Model control group | 378.5±61.3 | ? |
| Positive controls | 210.3±89.8 * | 44.4 |
| Test group | ? 151.4±54.9 **$ | 60.0 |
With model control group comparison,
* p< 0.05,
* p< 0.01;
With positive controls comparison,
$ p< 0.05.
Claims (1)
1. a coarse cereal fruit vegetable food with cancer-resisting effect, is characterized in that being prepared from by the raw material that comprises following ratio of weight and number: corn 10-16 part, seed of Job's tears 10-16 part, black rice 8-13 part, oatmeal 8-13 part, black buckwheat 8-13 part, polished rice 8-13 part, mung bean 11-15 part, pumpkin 5-9 part, balsam pear 5-9 part, Ipomoea batatas 5-9 part, matrimony vine 5-8 part, fennel seeds 3-5 part, Radix spinach 3-5 part;
The method for making of described coarse cereal fruit vegetable food, comprises the steps:
(1) be soaked in 12-20min in 20-30 ℃ of water after getting respectively the decortication of corn, black buckwheat, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, pulverize, cross 60-80 mesh sieve, standby;
(2) get the seed of Job's tears, remove cot, put in preheating frying container, with slow fire heating, fry to surperficial micro-yellow, slightly heave, during tool fragrance, take out and pulverize, cross 60-80 mesh sieve, standby;
(3) get respectively black rice, oatmeal, polished rice and be soaked in 12-20min in 20-30 ℃ of water, be placed in steamer and cook, proceed to the baking oven inner drying of 70-75 ℃, 145-160 ℃ of frying 10-20min, microwave bulking 5-10min, pulverizes, and crosses 60-80 mesh sieve, standby;
(4) get mung bean, be soaked in 20-40min in 35-45 ℃ of water, after taking-up, put into boiling water and boil 15-20min, well-done mung bean is drained away the water, be placed in steamer and cook 10-15min to the thorough slaking of mung bean, then send in dryer, with the 80-100 ℃ of dry 2-4h that dries, to mung bean moisture be 5%-7%, pulverized 60-80 mesh sieve, standby;
(5) get pumpkin respectively, sweet potato washing is clean, peeling stripping and slicing, put into water and soak 25-30min, then at-30 ℃, carry out quick-frozen vacuum drying, the quick-frozen time is 1.5-2h, when vacuum reaches 5Pa, takes out, and pulverizes 60-80 mesh sieve, standby;
(6) getting balsam pear cleans, dry, section, every thickness is 0.1～0.2 centimetre, under the sunlight of 20 ℃～30 ℃ of temperature, shines 2～3 hours, make balsam pear contained humidity be removed 10%～20%, balsam pear slice after Exposure to Sunlight is put into dryer, with the 80-90 ℃ of dry 5-9h that dries, to balsam pear contained humidity be lower than 5%, pulverized 60-80 mesh sieve, standby;
(7) get respectively matrimony vine, fennel seeds, Radix spinach, the baking oven inner drying 15-30min of 90-100 ℃, pulverized 60-80 mesh sieve, standby;
(8) material powder after above-mentioned processing is mixed, be directly prepared into coarse cereal fruit vegetable food; Or the material powder after above-mentioned processing is mixed, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food after thickener.
2. coarse cereal fruit vegetable food according to claim 1, is characterized in that: in step (3), the power of microwave bulking is 1500-2000W.
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| CN103380886A (en) * | 2013-06-17 | 2013-11-06 | 丁邦友 | Pumpkin-sweet potato-mung bean cake and processing method |
| CN103549302A (en) * | 2013-11-01 | 2014-02-05 | 合肥市财锦食品有限公司 | Immunity-improving health-care coarse cereals and preparation method thereof |
| CN103549303A (en) * | 2013-11-01 | 2014-02-05 | 合肥市财锦食品有限公司 | Compound health-care green bean and pearl barley coarse cereals and preparation method thereof |
| CN106136038A (en) * | 2016-06-30 | 2016-11-23 | 武汉枫阳生物科技有限公司 | A kind of grain rice meal replacement powder |
| CN107752011A (en) * | 2017-11-02 | 2018-03-06 | 孙沈平 | A kind of food compositions and application thereof |
| CN108497277A (en) * | 2018-01-27 | 2018-09-07 | 江西永昇制药股份有限公司 | Compound fruit and vegetable anticancer nutritional meal formula |
| CN109156718A (en) * | 2018-09-23 | 2019-01-08 | 李红光 | A kind of coarse food |
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| CN101543274A (en) * | 2009-04-16 | 2009-09-30 | 张昌才 | Crop rice and its preparation method |
| CN102696968A (en) * | 2012-06-25 | 2012-10-03 | 吉林大学 | Miscellaneous grain and miscellaneous bean instant noodles for children and preparation method of same |
| CN102715406A (en) * | 2012-07-17 | 2012-10-10 | 安徽燕之坊食品有限公司 | Coarse cereal full-nutrient food and preparation method thereof |
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