CN102860460A - Coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects and production method thereof - Google Patents

Coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects and production method thereof Download PDF

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Publication number
CN102860460A
CN102860460A CN2012103935079A CN201210393507A CN102860460A CN 102860460 A CN102860460 A CN 102860460A CN 2012103935079 A CN2012103935079 A CN 2012103935079A CN 201210393507 A CN201210393507 A CN 201210393507A CN 102860460 A CN102860460 A CN 102860460A
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coarse cereal
cancer
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vegetable food
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CN102860460B (en
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张丽琍
祁斌
吴雷
张超
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Anhui Yanzhifang Food Co Ltd
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Anhui Yanzhifang Food Co Ltd
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Abstract

The invention discloses coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects, which is prepared by the following raw materials by weight: 10-16 parts of corns, 10-16 parts of pearl barley, 8-13 parts of black rice, 8-13 parts of oatmeal, 8-13 parts of black buckwheat, 8-13 parts of polished round-grained rice, 11-15 parts of mung beans, 5-9 parts of pumpkins, 5-9 parts of balsam pears, 5-9 parts of sweet potato, 5-8 parts of medlar, 3-5 parts of fennel and 3-5 parts of spinach roots. According to the coarse cereal, fruit and vegetable food provided by the invention, the diet structure of people with cancer is reasonably adjusted, nutrient substances are replenished, and resitsance of an organism immune system on cancer cells is enhanced.

Description

A kind of coarse cereal fruit vegetable food and method for making thereof with cancer-resisting effect
Technical field
The present invention relates to a kind of functional food, in particular to a kind of coarse cereal fruit vegetable food and method for making thereof with cancer-resisting effect, belong to health food processing technique field.
Background technology
Cancer is common frdquently encountered disease, and people's life and healthy in serious harm, because the position of pathogenesis of cancer is different, various cancer can be arranged, such as non-small cell lung cancer, cancer of the stomach, lung cancer, osteocarcinoma, cutaneum carcinoma, intestinal cancer, liver cancer etc.Cancer cell is different from normal structure and cell, not according to Normocellular metabolic rule growth, thereby becomes unfettered and control, and is irregular ramp, so that can destroy the structure of normal structure organ and affect its function.Cancer cell is compared with normal cell, and the unusual of structure, function and metabolism arranged, and they have paranormal Reproductive activity, and this hyperplasia and body are not in tune.Pernicious cancer cell can infiltrate towards periphery and spread, even diffusion transfer continues to increase exponentially to other organ, causes human body or life are endangered greatly.
Because the cancer factor and endocrine variation; the cancer patient usually has appetite decline, the sense of taste changes; the metabolic mechanism of each large nutriment of body interior all changes; Body weight loss and nutrient depletion occur, and the depleted cachexia down to cancer occurring of nutrition is patient's the basic cause of death thereupon.In addition, the various treatment means for cancer that adopt at present are such as radiotherapy, chemotherapy, operation etc., be another test to cancer patient's sick body, such as chemotherapy, might cause strong digestive tract reaction, patient is perplexed by serious nauseating, vomiting in chemotherapy stage, almost can not take food.Even some embolic chemotherapy can cause directly that nutriment runs off at kidney and enteron aisle, causes patient's nutrition famine.Show that according to foreign data accept the patient of radiotherapy, chemotherapy in hospital, nearly 20%-40% dies from severe malnutrition.This shows that the cancer patient is very important in the nutritional support of radiotherapy or chemotherapeutic period.
Coarse cereals refer to other grains except rice and wheat, are the general names of essay kind cereal, essay kind beans and potato class; Mainly contain buckwheat, oat, barley, formal little slender bamboo wheat, rotten broomcorn millet, millet, corn, waxy corn, broad bean, pea, mung bean, black soya bean, kidney bean, red bean etc.China is a large agricultural country, and the coarse cereals resource is very abundant, is maximum in the world " coarse cereals kingdom ".The coarse cereals plantation is with a long history, various in style, widely distributed.According to statistics, 2002, the area of China's buckwheat, rotten broomcorn millet and output occupied the 2nd in the world, and yield of broad bean accounts for 1/2 of Gross World Product, and mung bean, red bean output account for 1/3 of Gross World Product, are the main product states of oat, cowpea, French beans.Coarse cereals are the pollution-free natural pollution-free foods of generally acknowledging, have special food treatment of food therapy effect, have critical role in the modern safety health food.The rational proportion that the nutritional labelings such as the protein in the coarse cereals, fat, carbohydrate, vitamin, mineral matter, cellulose meet that human body takes in has abundant nutritive value.Traditional Chinese Medicine is thought " plain tea and simple food, good for health ".Huangdi's Internal Classics is pointed out: " supporting vital QI with five kinds of grains, assisting vital QI with five kinds of fruits, reinforcing vital QI with meats of five livestock, supplementing vital QI with five kinds of veg etables, taking the mixed foods of various natures and flavors is with replenishing vital essence and invigorating vital QI." think that diet will accomplish comprehensive supply of healthy desired nutritional, could body building, promote longevity.
Because coarse cereals are the pollution-free natural pollution-free foods of generally acknowledging, have special food treatment of food therapy effect, therefore by a kind of coarse cereal fruit vegetable food with cancer-resisting effect of experimental study exploitation, this seems necessary.
Summary of the invention
The object of the invention is to by various coarse cereals, fruits and vegetables and consumption are screened and prescription, a kind of coarse cereal fruit vegetable food and method for making thereof with cancer-resisting effect is provided.Unexpectedly, coarse cereal fruit vegetable food of the present invention can not only reach the purpose of reasonable adjustment cancer patient dietary structure, and in the extra-nutrition material, strengthened the resistance of body immune system to cancer cell, both can be used as cancer patient's nutritional health food, also can be by often eating the purpose that reaches pre-anti-cancer.
First bright purpose of this law is achieved in that
A kind of coarse cereal fruit vegetable food with cancer-resisting effect is prepared from by the raw material that comprises following ratio of weight and number: corn 10-16 part, seed of Job's tears 10-16 part, black rice 8-13 part, oatmeal 8-13 part, black buckwheat 8-13 part, polished rice 8-13 part, mung bean 11-15 part, pumpkin 5-9 part, balsam pear 5-9 part, Ipomoea batatas 5-9 part, matrimony vine 5-8 part, fennel seeds 3-5 part, Radix spinach 3-5 part.
Second purpose of the present invention is like this test:
A kind of method for making of above-mentioned coarse cereal fruit vegetable food comprises the steps:
(1) be soaked in 12-20min in the 20-30 ℃ of water after getting respectively corn, the decortication of black buckwheat, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, pulverize, cross the 60-80 mesh sieve, for subsequent use;
(2) get the seed of Job's tears, remove cot, put in the preheating frying container, with the slow fire heating, fry to surperficial little yellow, slightly heave, during tool fragrance, take out and pulverize, cross the 60-80 mesh sieve, for subsequent use;
(3) get respectively black rice, oatmeal, polished rice and be soaked in 12-20min in the 20-30 ℃ of water, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, 145-160 ℃ of frying 10-20min, microwave bulking 5-10min pulverizes, and crosses the 60-80 mesh sieve, and is for subsequent use;
(4) get mung bean, be soaked in 20-40min in the 35-45 ℃ of water, put into boiling water after the taking-up and boil 15-20min, well-done mung bean is drained away the water, place to cook 10-15min in the steamer to the thorough slaking of mung bean, then send in the dryer, do baking 2-4h with 80-100 ℃, to the mung bean moisture be 5%-7%, pulverized the 60-80 mesh sieve, for subsequent use;
(5) get pumpkin respectively, sweet potato washing is clean, the peeling stripping and slicing, put into water and soak 25-30min, then carry out the quick-frozen vacuum drying at-30 ℃, the quick-frozen time is 1.5-2h, takes out when vacuum reaches 5Pa, pulverizes the 60-80 mesh sieve, and is for subsequent use;
(6) getting balsam pear cleans, dry, section, every thickness is 0.1~0.2 centimetre, shines 2~3 hours under the sunlight of 20 ℃~30 ℃ of temperature, make the balsam pear contained humidity be removed 10%~20%, balsam pear slice after the Exposure to Sunlight is put into dryer, does baking 5-9h with 80-90 ℃, to the balsam pear contained humidity for being lower than 5%, pulverized the 60-80 mesh sieve, for subsequent use;
(7) get respectively matrimony vine, fennel seeds, Radix spinach, 90-100 ℃ baking oven inner drying 15-30min pulverized the 60-80 mesh sieve, and was for subsequent use;
(8) with the material powder mixing after the above-mentioned processing, directly be prepared into coarse cereal fruit vegetable food; Or with the material powder mixing after the above-mentioned processing, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food behind the thickener.
Preferably, the method for making of above-mentioned coarse cereal fruit vegetable food, wherein the power of microwave bulking is 1500-2000W in the step (3).
Compared with prior art, the coarse cereal fruit vegetable food that the present invention relates to can not only reach the purpose of reasonable adjustment cancer patient dietary structure, and in the extra-nutrition material, strengthened the resistance of body immune system to cancer cell, both can be used as cancer patient's nutritional health food, also can be by often eating the purpose that reaches pre-anti-cancer.Table 1 by the effect test example can be found out, compare with control group, test group all has significant difference to the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, especially compare with model control group, the present invention raise with coarse cereal fruit vegetable feeding experiment group aspect the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, have utmost point significant difference ( P<0.01), compare with the positive controls of basal feed and to have significant difference with raising ( P<0.05).This is indicating that coarse cereal fruit vegetable food of the present invention can the fiting chemical treatment reach very effectively anticancer function.
 
The specific embodiment
Form is described in further detail foregoing of the present invention again by the following examples, but this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following embodiment, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
 
Embodiment 1
Composition of raw materials: 15 kilograms of corns, 13.5 kilograms of the seeds of Job's tears, 10.3 kilograms of black rices, 10.2 kilograms of oatmeals, 11 kilograms in black buckwheat, 12.5 kilograms of polished rices, 13.8 kilograms in mung bean, 7.5 kilograms in pumpkin, 6.8 kilograms in balsam pear, 8.2 kilograms in Ipomoea batatas, 6 kilograms of matrimony vines, 4.1 kilograms of fennel seeds, 4 kilograms of Radix spinach.
Processing step:
(1) be soaked in 15min in the 20-30 ℃ of water after taking by weighing respectively corn, the decortication of black buckwheat, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, pulverize, cross 80 mesh sieves, for subsequent use;
(2) take by weighing the seed of Job's tears, remove cot, put in the preheating frying container, with the slow fire heating, fry to surperficial little yellow, slightly heave, during tool fragrance, take out and pulverize, cross 80 mesh sieves, for subsequent use;
(3) take by weighing respectively black rice, oatmeal, polished rice and be soaked in 15min in the 20-30 ℃ of water, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, 150 ℃ of left and right sides frying 10-20min, microwave bulking 8min pulverizes, and crosses 80 mesh sieves, and is for subsequent use;
(4) take by weighing mung bean, be soaked in 30min in the 35-45 ℃ of water, put into boiling water after the taking-up and boil 15min, well-done mung bean is drained away the water, place to cook 10-15min in the steamer to the thorough slaking of mung bean, then send in the dryer, do baking 2-4h with 80-100 ℃, to the mung bean moisture be 5%-7%, pulverized 80 mesh sieves, for subsequent use;
(5) take by weighing pumpkin respectively, sweet potato washing is clean, the peeling stripping and slicing, put into water and soak 25-30min, then carry out the quick-frozen vacuum drying at-30 ℃, the quick-frozen time is 1.5-2h, takes out when vacuum reaches 5Pa, pulverizes 80 mesh sieves, and is for subsequent use;
(6) taking by weighing balsam pear cleans, dry, section, every thickness is 0.2 centimetre, shines 2~3 hours under the sunlight of 20 ℃~30 ℃ of temperature, make the balsam pear contained humidity be removed 10%~20%, balsam pear slice after the Exposure to Sunlight is put into dryer, does baking 5-9h with 90 ℃, to the balsam pear contained humidity for being lower than 5%, pulverized 80 mesh sieves, for subsequent use;
(7) take by weighing respectively matrimony vine, fennel seeds, Radix spinach, 90-100 ℃ baking oven inner drying 25min pulverized 80 mesh sieves, and was for subsequent use;
(8) with the material powder mixing after the above-mentioned processing, directly be prepared into coarse cereal fruit vegetable food, such as noodles; Or with the material powder mixing after the above-mentioned processing, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food behind the thickener, such as the nutrient breakfast that can reconstitute.
 
Embodiment 2 coarse cereal fruit vegetable food of the present invention are to people's lung cancer A549 cell transplanted tumor in nude mice affects on the growth
(1) preparation of coarse cereal fruit vegetable feed
Coarse cereal powder composition: the mixed material powder that is prepared from according to the composition and engineering of embodiment 1.
Basal feed: commercially available conventional test mouse feed, the content of protein wherein, fat, minerals and vitamins are to guarantee that growing of growing animal is necessary.
Coarse cereal fruit vegetable feed: made by 77.5% basal feed and 22.5% coarse cereal powder by weight percentage.
(2) preparation of people's lung cancer Nude Mouse Model
50 of SPF level BALB/c-nu mouse, 6 ages in week, body weight l8g-20 g.The lung cancer cell line A549 cell in growth period of taking the logarithm, adjusting the A549 cell concentration with aseptic PBS is 3 * 10 7/ mL at BALB/c-nu mouse back subcutaneous vaccination A549 cell 0.1ml, treats that subcutaneous transplantation knurl volume reaches 75 mm 3During the left and right sides (about lOd), the model manufacturing success.
(3) grouping and administration
Be divided into following three groups by knurl volume and mice with tumor body weight homeostatic principle, 15 every group, and raise with corresponding feed:
Model control group: freely drink water, raise with basal feed.
Positive controls: freely drink water, raise with basal feed, lumbar injection 15mg/kg oxaliplatin simultaneously, the next day administration 1 time, amount to 8 times.
Test group: freely drink water, raise with the coarse cereal fruit vegetable feed, lumbar injection 15mg/kg oxaliplatin simultaneously, the next day administration 1 time, amount to 8 times.
Mouse is put to death in dislocation behind last administration 48 h, the excision transplantable tumor, and it is heavy to take by weighing knurl.Heavy inhibiting rate (%) IR of knurl=(1-experimental group knurl weight-average value/model control group knurl weight-average value) * 100%.Relatively the embody medicine heavy by knurl suppresses the knurl affects on the growth to people's lung cancer A549 cell nude mice.
(4) test results and analysis
Result of the test shows (referring to table 1): compare with control group, test group all has significant difference to the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, especially compare with model control group, the present invention raise with coarse cereal fruit vegetable feeding experiment group aspect the inhibitory action of people's lung cancer A549 cell transplanted tumor in nude mice growth, have utmost point significant difference ( P<0.01), compare with the positive controls of basal feed and to have significant difference with raising ( P<0.05).This is indicating that coarse cereal fruit vegetable food of the present invention can the fiting chemical treatment reach very effectively anticancer function.
Table 1 coarse cereal fruit vegetable feed is to people's lung cancer A549 cell transplanted tumor in nude mice affects on the growth
Group Knurl weight/mg Average tumour inhibiting rate/%
Model control group 378.5±61.3 ?
Positive controls 210.3±89.8 * 44.4
Test group ? 151.4±54.9 **$ 60.0
Compare with model control group, * P<0.05, * P<0.01;
Compare with positive controls, $ P<0.05.

Claims (3)

1. the coarse cereal fruit vegetable food with cancer-resisting effect is characterized in that being prepared from by the raw material that comprises following ratio of weight and number: corn 10-16 part, seed of Job's tears 10-16 part, black rice 8-13 part, oatmeal 8-13 part, black buckwheat 8-13 part, polished rice 8-13 part, mung bean 11-15 part, pumpkin 5-9 part, balsam pear 5-9 part, Ipomoea batatas 5-9 part, matrimony vine 5-8 part, fennel seeds 3-5 part, Radix spinach 3-5 part.
2. the method for making of described coarse cereal fruit vegetable food according to claim 1 is characterized in that comprising the steps:
(1) be soaked in 12-20min in the 20-30 ℃ of water after getting respectively corn, the decortication of black buckwheat, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, pulverize, cross the 60-80 mesh sieve, for subsequent use;
(2) get the seed of Job's tears, remove cot, put in the preheating frying container, with the slow fire heating, fry to surperficial little yellow, slightly heave, during tool fragrance, take out and pulverize, cross the 60-80 mesh sieve, for subsequent use;
(3) get respectively black rice, oatmeal, polished rice and be soaked in 12-20min in the 20-30 ℃ of water, place in the steamer to cook, change 70-75 ℃ baking oven inner drying over to, 145-160 ℃ of frying 10-20min, microwave bulking 5-10min pulverizes, and crosses the 60-80 mesh sieve, and is for subsequent use;
(4) get mung bean, be soaked in 20-40min in the 35-45 ℃ of water, put into boiling water after the taking-up and boil 15-20min, well-done mung bean is drained away the water, place to cook 10-15min in the steamer to the thorough slaking of mung bean, then send in the dryer, do baking 2-4h with 80-100 ℃, to the mung bean moisture be 5%-7%, pulverized the 60-80 mesh sieve, for subsequent use;
(5) get pumpkin respectively, sweet potato washing is clean, the peeling stripping and slicing, put into water and soak 25-30min, then carry out the quick-frozen vacuum drying at-30 ℃, the quick-frozen time is 1.5-2h, takes out when vacuum reaches 5Pa, pulverizes the 60-80 mesh sieve, and is for subsequent use;
(6) getting balsam pear cleans, dry, section, every thickness is 0.1~0.2 centimetre, shines 2~3 hours under the sunlight of 20 ℃~30 ℃ of temperature, make the balsam pear contained humidity be removed 10%~20%, balsam pear slice after the Exposure to Sunlight is put into dryer, does baking 5-9h with 80-90 ℃, to the balsam pear contained humidity for being lower than 5%, pulverized the 60-80 mesh sieve, for subsequent use;
(7) get respectively matrimony vine, fennel seeds, Radix spinach, 90-100 ℃ baking oven inner drying 15-30min pulverized the 60-80 mesh sieve, and was for subsequent use;
(8) with the material powder mixing after the above-mentioned processing, directly be prepared into coarse cereal fruit vegetable food; Or with the material powder mixing after the above-mentioned processing, add flavor enhancement or/and be prepared into coarse cereal fruit vegetable food behind the thickener.
3. the method for making of described coarse cereal fruit vegetable food according to claim 2, it is characterized in that: the power of microwave bulking is 1500-2000W in the step (3).
CN201210393507.9A 2012-10-17 2012-10-17 Coarse cereal, fruit and vegetable food with cancer prevention and anti-cancer effects and production method thereof Active CN102860460B (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103380886A (en) * 2013-06-17 2013-11-06 丁邦友 Pumpkin-sweet potato-mung bean cake and processing method
CN103549302A (en) * 2013-11-01 2014-02-05 合肥市财锦食品有限公司 Immunity-improving health-care coarse cereals and preparation method thereof
CN103549303A (en) * 2013-11-01 2014-02-05 合肥市财锦食品有限公司 Compound health-care green bean and pearl barley coarse cereals and preparation method thereof
CN106136038A (en) * 2016-06-30 2016-11-23 武汉枫阳生物科技有限公司 A kind of grain rice meal replacement powder
CN107752011A (en) * 2017-11-02 2018-03-06 孙沈平 A kind of food compositions and application thereof
CN108497277A (en) * 2018-01-27 2018-09-07 江西永昇制药股份有限公司 Compound fruit and vegetable anticancer nutritional meal formula
CN109156718A (en) * 2018-09-23 2019-01-08 李红光 A kind of coarse food

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Publication number Priority date Publication date Assignee Title
CN101543274A (en) * 2009-04-16 2009-09-30 张昌才 Crop rice and its preparation method
CN102696968A (en) * 2012-06-25 2012-10-03 吉林大学 Miscellaneous grain and miscellaneous bean instant noodles for children and preparation method of same
CN102715406A (en) * 2012-07-17 2012-10-10 安徽燕之坊食品有限公司 Coarse cereal full-nutrient food and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101543274A (en) * 2009-04-16 2009-09-30 张昌才 Crop rice and its preparation method
CN102696968A (en) * 2012-06-25 2012-10-03 吉林大学 Miscellaneous grain and miscellaneous bean instant noodles for children and preparation method of same
CN102715406A (en) * 2012-07-17 2012-10-10 安徽燕之坊食品有限公司 Coarse cereal full-nutrient food and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103380886A (en) * 2013-06-17 2013-11-06 丁邦友 Pumpkin-sweet potato-mung bean cake and processing method
CN103549302A (en) * 2013-11-01 2014-02-05 合肥市财锦食品有限公司 Immunity-improving health-care coarse cereals and preparation method thereof
CN103549303A (en) * 2013-11-01 2014-02-05 合肥市财锦食品有限公司 Compound health-care green bean and pearl barley coarse cereals and preparation method thereof
CN106136038A (en) * 2016-06-30 2016-11-23 武汉枫阳生物科技有限公司 A kind of grain rice meal replacement powder
CN107752011A (en) * 2017-11-02 2018-03-06 孙沈平 A kind of food compositions and application thereof
CN108497277A (en) * 2018-01-27 2018-09-07 江西永昇制药股份有限公司 Compound fruit and vegetable anticancer nutritional meal formula
CN109156718A (en) * 2018-09-23 2019-01-08 李红光 A kind of coarse food

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