CN102859362B - 感染预后分析 - Google Patents

感染预后分析 Download PDF

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Publication number
CN102859362B
CN102859362B CN201180008422.8A CN201180008422A CN102859362B CN 102859362 B CN102859362 B CN 102859362B CN 201180008422 A CN201180008422 A CN 201180008422A CN 102859362 B CN102859362 B CN 102859362B
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CN
China
Prior art keywords
flc
infection
amount
sample
light chain
Prior art date
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Active
Application number
CN201180008422.8A
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English (en)
Chinese (zh)
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CN102859362A (zh
Inventor
G·米德
A·布拉德韦尔
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Binding Site Group Ltd
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Binding Site Group Ltd
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Publication of CN102859362A publication Critical patent/CN102859362A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201180008422.8A 2010-02-05 2011-02-04 感染预后分析 Active CN102859362B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1001950.3A GB201001950D0 (en) 2010-02-05 2010-02-05 Infection prognostic assay
GB1001950.3 2010-02-05
PCT/GB2011/050197 WO2011095820A1 (en) 2010-02-05 2011-02-04 Infection prognostic assay

Publications (2)

Publication Number Publication Date
CN102859362A CN102859362A (zh) 2013-01-02
CN102859362B true CN102859362B (zh) 2015-11-25

Family

ID=42082582

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201180008422.8A Active CN102859362B (zh) 2010-02-05 2011-02-04 感染预后分析
CN201180008402.0A Active CN102859361B (zh) 2010-02-05 2011-02-04 癌症预后分析

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201180008402.0A Active CN102859361B (zh) 2010-02-05 2011-02-04 癌症预后分析

Country Status (6)

Country Link
US (2) US20130149792A1 (cg-RX-API-DMAC7.html)
EP (1) EP2531857B1 (cg-RX-API-DMAC7.html)
JP (2) JP5818818B2 (cg-RX-API-DMAC7.html)
CN (2) CN102859362B (cg-RX-API-DMAC7.html)
GB (1) GB201001950D0 (cg-RX-API-DMAC7.html)
WO (1) WO2011095820A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2519564A (en) * 2013-10-24 2015-04-29 Shared Band Ltd Multicast transmission over bonded broadband
US20170268070A1 (en) 2014-07-30 2017-09-21 Mor Research Applications Ltd. Prognostic methods and systems of treatment for acute lymphoblastic leukemia

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792529A (en) * 1985-10-18 1988-12-20 University Of Rochester Immunoassay of free kappa light chains for the detection of multiple sclerosis
EP0336472A1 (en) * 1988-04-01 1989-10-11 New Scientific Company S.P.A. Method for determining the presence of free light chains in urine samples, complex of preparations for performance of the method and related reagent

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997017372A1 (en) 1995-11-03 1997-05-15 The Binding Site Limited Production of antibodies, and medical uses involving antibodies
US6322788B1 (en) * 1998-08-20 2001-11-27 Stanley Arthur Kim Anti-bacterial antibodies and methods of use
US20040018576A1 (en) * 2002-07-24 2004-01-29 Dematteo Todd M. Bence Jones protein testing cassette
JP4438455B2 (ja) * 2004-03-04 2010-03-24 ヤマサ醤油株式会社 遊離ヒトイムノグロブリン軽鎖の測定法及びキット
WO2005116651A2 (en) * 2004-05-24 2005-12-08 Diasys Corporation Method and device for testing for bence-jones protein
US20090082304A1 (en) * 2004-11-12 2009-03-26 Northwestern University Methods of Treating Hematological Malignancies with Nucleoside Analog Drugs
GB0501741D0 (en) * 2005-01-27 2005-03-02 Binding Site The Ltd Antibody
EP1870710B1 (en) * 2005-04-12 2011-03-23 Akira Matsumori Biomarker for diagnosing heart disease and the use thereof
JP2007292661A (ja) * 2006-04-26 2007-11-08 Akira Matsumori 活動性心筋炎の検出方法および検出試薬
GB0801609D0 (en) * 2008-01-29 2008-03-05 Binding Site The Ltd Hevylite diagnostic stain

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792529A (en) * 1985-10-18 1988-12-20 University Of Rochester Immunoassay of free kappa light chains for the detection of multiple sclerosis
EP0336472A1 (en) * 1988-04-01 1989-10-11 New Scientific Company S.P.A. Method for determining the presence of free light chains in urine samples, complex of preparations for performance of the method and related reagent

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Borderline High Serum Free Light Chain κ/λ Ratios Are Seen Not Only in Dialysis Patients but Also in Non–Dialysis-Dependent Renal Impairment and Inflammatory States;George marshall et al;《Am J Clin Pathol》;20091231;第132卷;第309页右栏第1段 *
Free kappa and lambda light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases;O.C. Fagnart;《Journal of Neuroimmunology》;19880101;第19卷(第1-2期);摘要，图1-4 *
Free light chains in multiple sclerosis and infections of the CNS;Charles DeCarli,MD;《neurology》;19870831;第1334-1338页 *
Quantitative Assessment of Serumand Urinary Polyclonal Free Light Chains in Patients with Chronic Kidney Disease;Colin A.Hutchison;《Clin. J. Am. Soc. Nephrol》;20081231;第3卷;第1684-1690页 *

Also Published As

Publication number Publication date
CN102859361B (zh) 2015-06-17
JP5818817B2 (ja) 2015-11-18
US20130149792A1 (en) 2013-06-13
EP2531857B1 (en) 2017-01-18
CN102859362A (zh) 2013-01-02
US20130217030A1 (en) 2013-08-22
WO2011095820A1 (en) 2011-08-11
JP5818818B2 (ja) 2015-11-18
CN102859361A (zh) 2013-01-02
JP2013519082A (ja) 2013-05-23
GB201001950D0 (en) 2010-03-24
EP2531857A1 (en) 2012-12-12
JP2013519083A (ja) 2013-05-23

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