CN102844334A - 用于制备聚氟代丙烯酸酯粒子的连续方法 - Google Patents

用于制备聚氟代丙烯酸酯粒子的连续方法 Download PDF

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Publication number
CN102844334A
CN102844334A CN2011800184692A CN201180018469A CN102844334A CN 102844334 A CN102844334 A CN 102844334A CN 2011800184692 A CN2011800184692 A CN 2011800184692A CN 201180018469 A CN201180018469 A CN 201180018469A CN 102844334 A CN102844334 A CN 102844334A
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CN
China
Prior art keywords
formula
structural unit
reactor
polymer
described method
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Pending
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CN2011800184692A
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English (en)
Chinese (zh)
Inventor
G·泰森
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Relypsa Inc
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Relypsa Inc
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Publication of CN102844334A publication Critical patent/CN102844334A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/22—Esters containing halogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/01—Processes of polymerisation characterised by special features of the polymerisation apparatus used
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/22—Esters containing halogen
    • C08F220/24—Esters containing halogen containing perhaloalkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
    • C08F36/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/34—Monomers containing two or more unsaturated aliphatic radicals
    • C08F212/36—Divinylbenzene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F236/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F236/22—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having three or more carbon-to-carbon double bonds

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymerisation Methods In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2011800184692A 2010-03-20 2011-03-18 用于制备聚氟代丙烯酸酯粒子的连续方法 Pending CN102844334A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31593710P 2010-03-20 2010-03-20
US61/315,937 2010-03-20
PCT/US2011/028950 WO2011119422A1 (en) 2010-03-20 2011-03-18 Continuous process for preparing polyfluoroacrylate particles

Publications (1)

Publication Number Publication Date
CN102844334A true CN102844334A (zh) 2012-12-26

Family

ID=43989862

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800184692A Pending CN102844334A (zh) 2010-03-20 2011-03-18 用于制备聚氟代丙烯酸酯粒子的连续方法

Country Status (12)

Country Link
US (1) US9228028B2 (enExample)
EP (1) EP2550305B1 (enExample)
JP (2) JP6185836B2 (enExample)
KR (1) KR101839038B1 (enExample)
CN (1) CN102844334A (enExample)
CA (1) CA2793862C (enExample)
ES (1) ES2670580T3 (enExample)
MX (1) MX347224B (enExample)
PL (1) PL2550305T3 (enExample)
PT (1) PT2550305T (enExample)
TR (1) TR201807469T4 (enExample)
WO (1) WO2011119422A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113929925A (zh) * 2020-07-13 2022-01-14 中国石油化工股份有限公司 一种自组装纳米粒子复合材料及其制备方法和应用
WO2023035274A1 (en) * 2021-09-13 2023-03-16 Waterstone Pharmaceuticals(Wuhan) Co., Ltd. Polymer medicament for treating hyperkalemia and preparation method thereof

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2882798B1 (en) 2012-08-09 2019-05-08 Patheon Austria GmbH & Co KG Process for drying polymeric materials
ES3059226T3 (en) 2012-10-08 2026-03-19 Vifor Int Ltd Potassium-binding agents for treating hypertension and hyperkalemia
WO2019220450A1 (en) 2018-05-16 2019-11-21 Solara Active Pharma Sciences Limited Process for preparation of patiromer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022380A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010022381A1 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
WO2010022383A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia
WO2010022382A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof

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US2694700A (en) 1950-01-21 1954-11-16 Peter L Shanta Process of suspension polymerization
DE1111823B (de) 1958-04-01 1961-07-27 Gerhard Schwarz Dipl Chem Verfahren und Vorrichtung zur kontinuierlichen Herstellung von ionenaustauschenden synthetischen stickstoffhaltigen Harzen in Kugelform
JPS5336510B2 (enExample) * 1972-05-15 1978-10-03
CA1166413A (en) 1980-10-30 1984-05-01 Edward E. Timm Process and apparatus for preparing uniform size polymer beads
US4487898A (en) * 1981-06-12 1984-12-11 Kanegafuchi Chemical Industry Co., Ltd. Process of continuous suspension polymerization
JPH0632805A (ja) 1992-07-17 1994-02-08 Asahi Chem Ind Co Ltd 連続重合プロセスの非定常運転時の制御方法
WO2000075193A1 (en) 1999-06-08 2000-12-14 Kaneka Corporation Method of continuous cationic living polymerization
JP2001055415A (ja) * 1999-06-08 2001-02-27 Kanegafuchi Chem Ind Co Ltd イソブチレン系重合体の製造方法
JP4509279B2 (ja) 2000-02-02 2010-07-21 日東電工株式会社 アクリル系感圧性接着剤の製造方法
EP1411076A1 (en) 2002-10-15 2004-04-21 Rohm And Haas Company Continuous production of crosslinked polymer nanoparticles
JP4062121B2 (ja) 2003-02-21 2008-03-19 旭硝子株式会社 フルオロポリマーの製造方法
KR101153035B1 (ko) 2004-03-30 2012-06-11 리립사, 인크. 이온 결합 조성물
JP2009062478A (ja) 2007-09-07 2009-03-26 Dic Corp 有機無機複合ヒドロゲルの連続製造方法
WO2009075387A1 (en) * 2007-12-13 2009-06-18 Daikin Industries, Ltd. Fluorine-containing polymer and aqueous treatment agent
US8148477B2 (en) 2008-03-14 2012-04-03 Konica Minolta Business Technologies, Inc. Tubular flow reactor and method of manufacturing polymeric resin fine particle

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022380A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010022381A1 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
WO2010022383A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia
WO2010022382A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113929925A (zh) * 2020-07-13 2022-01-14 中国石油化工股份有限公司 一种自组装纳米粒子复合材料及其制备方法和应用
CN113929925B (zh) * 2020-07-13 2023-08-15 中国石油化工股份有限公司 一种自组装纳米粒子复合材料及其制备方法和应用
WO2023035274A1 (en) * 2021-09-13 2023-03-16 Waterstone Pharmaceuticals(Wuhan) Co., Ltd. Polymer medicament for treating hyperkalemia and preparation method thereof

Also Published As

Publication number Publication date
MX347224B (es) 2017-04-19
EP2550305B1 (en) 2018-03-07
PL2550305T3 (pl) 2018-08-31
US9228028B2 (en) 2016-01-05
JP6185836B2 (ja) 2017-08-23
PT2550305T (pt) 2018-04-20
KR20130016252A (ko) 2013-02-14
JP2013522448A (ja) 2013-06-13
WO2011119422A1 (en) 2011-09-29
EP2550305A1 (en) 2013-01-30
US20130197170A1 (en) 2013-08-01
CA2793862A1 (en) 2011-09-29
KR101839038B1 (ko) 2018-03-16
JP2015131974A (ja) 2015-07-23
MX2012010850A (es) 2013-01-29
TR201807469T4 (tr) 2018-06-21
CA2793862C (en) 2020-07-07
ES2670580T3 (es) 2018-05-31

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Application publication date: 20121226