KR101839038B1 - 폴리플루오로아크릴레이트 입자를 제조하기 위한 연속식 방법 - Google Patents

폴리플루오로아크릴레이트 입자를 제조하기 위한 연속식 방법 Download PDF

Info

Publication number
KR101839038B1
KR101839038B1 KR1020127026246A KR20127026246A KR101839038B1 KR 101839038 B1 KR101839038 B1 KR 101839038B1 KR 1020127026246 A KR1020127026246 A KR 1020127026246A KR 20127026246 A KR20127026246 A KR 20127026246A KR 101839038 B1 KR101839038 B1 KR 101839038B1
Authority
KR
South Korea
Prior art keywords
reactor
formulas
polymer
particles
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020127026246A
Other languages
English (en)
Korean (ko)
Other versions
KR20130016252A (ko
Inventor
조지 타이슨
Original Assignee
리립사, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 리립사, 인크. filed Critical 리립사, 인크.
Publication of KR20130016252A publication Critical patent/KR20130016252A/ko
Application granted granted Critical
Publication of KR101839038B1 publication Critical patent/KR101839038B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/22—Esters containing halogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/01—Processes of polymerisation characterised by special features of the polymerisation apparatus used
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/34—Monomers containing two or more unsaturated aliphatic radicals
    • C08F212/36—Divinylbenzene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/22—Esters containing halogen
    • C08F220/24—Esters containing halogen containing perhaloalkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F36/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F36/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds
    • C08F36/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having only two carbon-to-carbon double bonds conjugated
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F236/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds
    • C08F236/22—Copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds the radical having three or more carbon-to-carbon double bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polymerisation Methods In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020127026246A 2010-03-20 2011-03-18 폴리플루오로아크릴레이트 입자를 제조하기 위한 연속식 방법 Expired - Fee Related KR101839038B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31593710P 2010-03-20 2010-03-20
US61/315,937 2010-03-20
PCT/US2011/028950 WO2011119422A1 (en) 2010-03-20 2011-03-18 Continuous process for preparing polyfluoroacrylate particles

Publications (2)

Publication Number Publication Date
KR20130016252A KR20130016252A (ko) 2013-02-14
KR101839038B1 true KR101839038B1 (ko) 2018-03-16

Family

ID=43989862

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127026246A Expired - Fee Related KR101839038B1 (ko) 2010-03-20 2011-03-18 폴리플루오로아크릴레이트 입자를 제조하기 위한 연속식 방법

Country Status (12)

Country Link
US (1) US9228028B2 (enExample)
EP (1) EP2550305B1 (enExample)
JP (2) JP6185836B2 (enExample)
KR (1) KR101839038B1 (enExample)
CN (1) CN102844334A (enExample)
CA (1) CA2793862C (enExample)
ES (1) ES2670580T3 (enExample)
MX (1) MX347224B (enExample)
PL (1) PL2550305T3 (enExample)
PT (1) PT2550305T (enExample)
TR (1) TR201807469T4 (enExample)
WO (1) WO2011119422A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104603182B (zh) 2012-08-09 2016-11-02 Dpx精细化学奥地利两合公司 干燥聚合材料的方法
EP2916851B1 (en) 2012-10-08 2025-12-17 Vifor (International) Ltd. Potassium-binding agents for treating hypertension and hyperkalemia
WO2019220450A1 (en) 2018-05-16 2019-11-21 Solara Active Pharma Sciences Limited Process for preparation of patiromer
CN113929925B (zh) * 2020-07-13 2023-08-15 中国石油化工股份有限公司 一种自组装纳米粒子复合材料及其制备方法和应用
CN116323717A (zh) * 2021-09-13 2023-06-23 中美华世通生物医药科技(武汉)股份有限公司 治疗高钾血症的聚合物药物及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022382A2 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof
WO2010022380A2 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010022383A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2694700A (en) 1950-01-21 1954-11-16 Peter L Shanta Process of suspension polymerization
DE1111823B (de) 1958-04-01 1961-07-27 Gerhard Schwarz Dipl Chem Verfahren und Vorrichtung zur kontinuierlichen Herstellung von ionenaustauschenden synthetischen stickstoffhaltigen Harzen in Kugelform
JPS5336510B2 (enExample) 1972-05-15 1978-10-03
CA1166413A (en) 1980-10-30 1984-05-01 Edward E. Timm Process and apparatus for preparing uniform size polymer beads
US4487898A (en) * 1981-06-12 1984-12-11 Kanegafuchi Chemical Industry Co., Ltd. Process of continuous suspension polymerization
JPH0632805A (ja) 1992-07-17 1994-02-08 Asahi Chem Ind Co Ltd 連続重合プロセスの非定常運転時の制御方法
JP2001055415A (ja) * 1999-06-08 2001-02-27 Kanegafuchi Chem Ind Co Ltd イソブチレン系重合体の製造方法
DE60041644D1 (de) 1999-06-08 2009-04-09 Kaneka Corp Verfahren zur kontinuierlichen katonischen lebenden polymerisation
JP4509279B2 (ja) 2000-02-02 2010-07-21 日東電工株式会社 アクリル系感圧性接着剤の製造方法
EP1411076A1 (en) 2002-10-15 2004-04-21 Rohm And Haas Company Continuous production of crosslinked polymer nanoparticles
JP4062121B2 (ja) 2003-02-21 2008-03-19 旭硝子株式会社 フルオロポリマーの製造方法
EP1732523B9 (en) 2004-03-30 2010-06-02 Relypsa, Inc. Potassium binding polymers and uses thereof
JP2009062478A (ja) 2007-09-07 2009-03-26 Dic Corp 有機無機複合ヒドロゲルの連続製造方法
CN104087108A (zh) * 2007-12-13 2014-10-08 大金工业株式会社 含氟聚合物和水性处理剂
WO2009113419A1 (ja) * 2008-03-14 2009-09-17 コニカミノルタビジネステクノロジーズ株式会社 管型フロー反応装置、高分子樹脂微粒子の製造方法
WO2010022381A1 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022382A2 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof
WO2010022380A2 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010022383A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia

Also Published As

Publication number Publication date
PT2550305T (pt) 2018-04-20
EP2550305A1 (en) 2013-01-30
US9228028B2 (en) 2016-01-05
JP2013522448A (ja) 2013-06-13
JP6185836B2 (ja) 2017-08-23
US20130197170A1 (en) 2013-08-01
PL2550305T3 (pl) 2018-08-31
JP2015131974A (ja) 2015-07-23
ES2670580T3 (es) 2018-05-31
CA2793862A1 (en) 2011-09-29
MX347224B (es) 2017-04-19
MX2012010850A (es) 2013-01-29
WO2011119422A1 (en) 2011-09-29
CN102844334A (zh) 2012-12-26
TR201807469T4 (tr) 2018-06-21
EP2550305B1 (en) 2018-03-07
CA2793862C (en) 2020-07-07
KR20130016252A (ko) 2013-02-14

Similar Documents

Publication Publication Date Title
KR101839038B1 (ko) 폴리플루오로아크릴레이트 입자를 제조하기 위한 연속식 방법
KR102150184B1 (ko) 가교결합된 양이온교환 폴리머, 조성물 및 고칼륨혈증 치료 용도
AU2013329451B2 (en) Potassium-binding agents for treating hypertension and hyperkalemia
WO2010022381A1 (en) Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
WO2010022380A2 (en) Linear polyol stabilized polyfluoroacrylate compositions
JP2013522448A5 (enExample)
Nyström et al. Construction of thermoresponsive SCKs through tuning the crystalline melting point of the core domain
WO2022138482A1 (ja) ポリマー含有ｏ／ｗ型エマルジョン組成物
AU2013204879B2 (en) Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia
Zhang et al. Preparation of hyperbranched polymer via single electron transfer living radical polymerization

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

A201 Request for examination
AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

AMND Amendment
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T13-X000 Administrative time limit extension granted

St.27 status event code: U-3-3-T10-T13-oth-X000

AMND Amendment
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PX0901 Re-examination

St.27 status event code: A-2-3-E10-E12-rex-PX0901

PX0701 Decision of registration after re-examination

St.27 status event code: A-3-4-F10-F13-rex-PX0701

X701 Decision to grant (after re-examination)
GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20220310

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20220310