CN102834386B - 具有氧化还原酶活性的多肽及其用途 - Google Patents

具有氧化还原酶活性的多肽及其用途 Download PDF

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Publication number
CN102834386B
CN102834386B CN201080039317.6A CN201080039317A CN102834386B CN 102834386 B CN102834386 B CN 102834386B CN 201080039317 A CN201080039317 A CN 201080039317A CN 102834386 B CN102834386 B CN 102834386B
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hmf
polypeptide
fdca
oxidoreductase
cell
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CN102834386A (zh
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哈拉德·约翰·鲁杰瑟纳斯
尼克·约翰尼斯·皮特斯·维尔克斯
弗兰克·沃特·库普曼
阿德里安努·约翰尼斯·约瑟夫·斯特拉索夫
约翰尼斯·翰德里克·温德·德
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Purac Biochem BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F124/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a heterocyclic ring containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Peptides Or Proteins (AREA)
CN201080039317.6A 2009-09-02 2010-09-02 具有氧化还原酶活性的多肽及其用途 Expired - Fee Related CN102834386B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09169227 2009-09-02
EP09169227.7 2009-09-02
EP09172555.6 2009-10-08
EP09172555 2009-10-08
PCT/EP2010/062896 WO2011026913A1 (en) 2009-09-02 2010-09-02 Polypeptides having oxidoreductase activity and their uses

Publications (2)

Publication Number Publication Date
CN102834386A CN102834386A (zh) 2012-12-19
CN102834386B true CN102834386B (zh) 2016-12-07

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Country Link
US (2) US9045787B2 (https=)
EP (2) EP2473494B1 (https=)
JP (2) JP5868320B2 (https=)
KR (1) KR101946649B1 (https=)
CN (1) CN102834386B (https=)
AU (1) AU2010291208B2 (https=)
BR (1) BR112012004802A2 (https=)
CA (1) CA2777503C (https=)
DK (2) DK2473494T3 (https=)
EA (1) EA025990B1 (https=)
ES (2) ES2885723T3 (https=)
IN (1) IN2012DN01652A (https=)
WO (1) WO2011026913A1 (https=)

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AU2010291208B2 (en) * 2009-09-02 2015-04-09 Purac Biochem B.V. Polypeptides having oxidoreductase activity and their uses
WO2011159092A2 (ko) 2010-06-14 2011-12-22 (주)아모레퍼시픽 신규 토양 미생물과 상기 토양 미생물로부터 분리된 신규한 산화환원효소, 상기 산화환원 효소를 암호화하는 유전자 및 이들을 이용한 비당체의 생산방법
NL2006359C2 (en) 2011-03-08 2012-04-24 Bird Engineering B V Genetically modified cell and process for use of said cell.
PL2744747T3 (pl) 2011-08-16 2021-06-28 Purac Biochem B.V. Odzyskiwanie kwasu karboksylowego z ich soli magnezowych poprzez wytrącanie z zastosowaniem kwasu chlorowodorowego, do zastosowania w pracy z bulionem fermentacyjnym
CN109134239A (zh) * 2011-08-16 2019-01-04 普拉克生化公司 可用于发酵液处理的通过用盐酸沉淀从羧酸镁盐中回收羧酸的方法
KR101217137B1 (ko) * 2012-03-05 2012-12-31 한국생산기술연구원 프록토오스를 포함하는 옥수수시럽으로부터 5-히드록시메틸-2-푸르푸랄을 제조하는 방법
US8609884B2 (en) 2012-03-19 2013-12-17 Awi Licensing Company Biobased plasticizer and surface covering employing same
CN104781412A (zh) * 2012-07-20 2015-07-15 诺维信公司 5-羟甲基糠醛及其衍生物的酶氧化
NL2011027C2 (en) * 2013-06-24 2014-12-29 Univ Delft Tech Process for the preparation of 2,5-furandicarboxylic acid.
CN104371955B (zh) * 2014-10-30 2017-02-08 江南大学 一种合成2,5‑呋喃二甲酸的土生拉乌尔菌及其应用
AU2016220612B2 (en) * 2015-02-17 2021-09-30 Purac Biochem B.V. Dehydrogenase-catalysed production of FDCA
JP6745276B2 (ja) 2015-03-17 2020-08-26 ピュラック バイオケム ビー． ブイ． 固体の塩からフラン−２，５−ジカルボン酸（ｆｄｃａ）を製造する方法
US9321744B1 (en) 2015-06-26 2016-04-26 Industrial Technology Research Institute Method for preparing 2,5-furan dicarboxylic acid
US11034979B2 (en) 2015-09-21 2021-06-15 Purac Biochem B.V. Fungal production of FDCA
WO2017098296A1 (en) 2015-12-11 2017-06-15 SOCIETE ANONYME DES EAUX MINERALES D'EVIAN et en abrégé "S.A.E.M.E" Pet polymer with an anti-crystallization comonomer that can be bio-sourced
JP7458147B2 (ja) 2016-01-13 2024-03-29 ストラ エンソ オーユーイー ２，５－フランジカルボン酸ならびにその中間体および誘導体の製造方法
EP3378931A1 (en) * 2017-03-21 2018-09-26 Purac Biochem B.V. Fdca-decarboxylating monooxygenase-deficient host cells for producing fdca
CA3069521A1 (en) 2017-07-12 2019-01-17 Stora Enso Oyj Purified 2,5-furandicarboxylic acid pathway products
US20210180095A1 (en) 2017-11-10 2021-06-17 Shell Oil Company Methods of producing 2,5-furandicarboxylic acid
CN108611380A (zh) * 2018-04-17 2018-10-02 华南理工大学 一种选择性合成2,5-二羟甲基呋喃的方法
CN109536466B (zh) * 2018-11-19 2022-04-22 华南理工大学 醛脱氢酶及其基因、重组菌构建及其在呋喃羧酸合成中的应用
WO2020176958A1 (en) 2019-03-01 2020-09-10 Braskem S.A. Method for the in vivo synthesis of 4-hydroxymethylfurfural and derivatives thereof
CN109811020B (zh) * 2019-03-20 2022-03-29 南京工业大学 利用乌鲁木齐奇异球菌催化合成5-羟甲基糠酸的方法
CA3142306A1 (en) 2019-06-06 2020-12-10 Purac Biochem B.V. Process for manufacturing hydroxymethylfurfural
CN110331174B (zh) * 2019-07-15 2020-12-25 南京林业大学 一种以石花菜为原料联产半乳糖酸和5-羟甲基-2-呋喃甲酸的方法
CN110511198A (zh) * 2019-08-31 2019-11-29 贵州大学 一种利用黑曲霉孢子粉分离提取5-羟甲基-呋喃甲酸的方法
JP2023534790A (ja) * 2020-07-15 2023-08-14 エボニック オペレーションズ ゲーエムベーハー オキシドレダクターゼをコードするアミノ酸配列をコードするポリヌクレオチド
CN114836395B (zh) * 2022-04-28 2024-04-26 华东理工大学 硫醚单加氧酶突变体及其在制备手性拉唑药物中的应用
CN116024184B (zh) * 2022-07-26 2024-03-15 南京科技职业学院 醛脱氢酶突变体及其在制备5-羟甲基-2-呋喃甲酸中的应用
CN118931775A (zh) * 2024-08-07 2024-11-12 秦皇岛果阳生物科技有限公司 一种复合微生物菌剂及其制备方法和应用

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Publication number Publication date
EP2473494B1 (en) 2019-06-12
EP3560915B1 (en) 2021-06-02
JP5868320B2 (ja) 2016-02-24
JP6372889B2 (ja) 2018-08-15
ES2744466T3 (es) 2020-02-25
US20150203882A1 (en) 2015-07-23
IN2012DN01652A (https=) 2015-06-05
AU2010291208B2 (en) 2015-04-09
US9481900B2 (en) 2016-11-01
US9045787B2 (en) 2015-06-02
WO2011026913A1 (en) 2011-03-10
JP2013503614A (ja) 2013-02-04
BR112012004802A2 (pt) 2015-09-08
KR101946649B1 (ko) 2019-02-11
ES2885723T3 (es) 2021-12-15
EA025990B1 (ru) 2017-02-28
DK2473494T3 (da) 2019-07-29
EP3560915A1 (en) 2019-10-30
KR20120083367A (ko) 2012-07-25
US20120309918A1 (en) 2012-12-06
AU2010291208A1 (en) 2012-03-29
CA2777503A1 (en) 2011-03-10
EA201200398A1 (ru) 2012-09-28
EP2473494A1 (en) 2012-07-11
JP2016073289A (ja) 2016-05-12
CN102834386A (zh) 2012-12-19
CA2777503C (en) 2018-10-16
DK3560915T3 (da) 2021-06-28

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