CN102778448A - 非线性拉曼光谱设备、显微光谱设备及显微光谱成像设备 - Google Patents
非线性拉曼光谱设备、显微光谱设备及显微光谱成像设备 Download PDFInfo
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- CN102778448A CN102778448A CN2012101392896A CN201210139289A CN102778448A CN 102778448 A CN102778448 A CN 102778448A CN 2012101392896 A CN2012101392896 A CN 2012101392896A CN 201210139289 A CN201210139289 A CN 201210139289A CN 102778448 A CN102778448 A CN 102778448A
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- Prior art keywords
- raman spectroscopy
- stokes
- light
- nonlinear raman
- wavelength
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
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- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Microscoopes, Condenser (AREA)
- Lasers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011108324A JP2012237714A (ja) | 2011-05-13 | 2011-05-13 | 非線形ラマン分光装置、顕微分光装置及び顕微分光イメージング装置 |
| JP2011-108324 | 2011-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102778448A true CN102778448A (zh) | 2012-11-14 |
Family
ID=46087418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101392896A Pending CN102778448A (zh) | 2011-05-13 | 2012-05-07 | 非线性拉曼光谱设备、显微光谱设备及显微光谱成像设备 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20120287428A1 (enExample) |
| EP (1) | EP2522969A3 (enExample) |
| JP (1) | JP2012237714A (enExample) |
| CN (1) | CN102778448A (enExample) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103280693A (zh) * | 2013-05-27 | 2013-09-04 | 深圳市盛世领航光电有限公司 | 气体rgb激光器和rgb三色激光的发生方法 |
| CN103487146A (zh) * | 2013-09-16 | 2014-01-01 | 华南师范大学 | 一种简便的超宽带受激拉曼光谱显微成像系统 |
| CN105247350A (zh) * | 2013-03-26 | 2016-01-13 | 国家科学研究中心 | 用于受激拉曼检测的设备和方法 |
| CN105683818A (zh) * | 2013-09-03 | 2016-06-15 | 徕卡显微系统复合显微镜有限公司 | 具有偏振的样品照明的扫描显微镜 |
| CN107064100A (zh) * | 2016-11-03 | 2017-08-18 | 北京信息科技大学 | 基于色散时变的光纤拉曼光谱仪 |
| CN107290056A (zh) * | 2017-06-30 | 2017-10-24 | 中国科学院半导体研究所 | 拉曼光谱测试系统 |
| CN108489959A (zh) * | 2018-03-21 | 2018-09-04 | 中山大学 | 一种相干反斯托克斯拉曼光谱扫描装置和方法 |
| CN109075523A (zh) * | 2016-01-22 | 2018-12-21 | 国立科学研究中心 | 用于生成具有基本上恒定的能量的多色光子束的设备 |
| CN109638620A (zh) * | 2018-12-06 | 2019-04-16 | 华南师范大学 | 一种基于掺Yb2+光纤的可见光光纤激光器 |
| CN109687267A (zh) * | 2018-12-06 | 2019-04-26 | 华南师范大学 | 一种用于产生561nm波长的光纤激光器 |
| CN119310726A (zh) * | 2024-12-03 | 2025-01-14 | 浙江大学 | 一种非线性焦点调制显微成像装置及方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9634454B1 (en) * | 2012-01-17 | 2017-04-25 | President And Fellows Of Harvard College | Laser illumination systems and methods for dual-excitation wavelength non-linear optical microscopy and micro-spectroscopy systems |
| US9478940B2 (en) * | 2012-10-05 | 2016-10-25 | Volcano Corporation | Systems and methods for amplifying light |
| WO2014125729A1 (ja) * | 2013-02-13 | 2014-08-21 | ソニー株式会社 | 測定装置及び測定方法 |
| JP2015007612A (ja) * | 2013-05-31 | 2015-01-15 | キヤノン株式会社 | 光源調整手段、光学計測装置、被検体情報取得システム、および波長調整プログラム |
| WO2015025389A1 (ja) * | 2013-08-22 | 2015-02-26 | 株式会社日立製作所 | Cars顕微鏡 |
| US20150204790A1 (en) * | 2014-01-23 | 2015-07-23 | Canon Kabushiki Kaisha | Stimulated raman scattering measurement apparatus |
| JP6340474B2 (ja) * | 2015-03-11 | 2018-06-06 | 株式会社日立ハイテクノロジーズ | 光計測装置及び光計測方法 |
| CN105352936B (zh) * | 2015-11-23 | 2018-05-22 | 哈尔滨工业大学 | 一种基于相干反斯托克斯拉曼散射效应的超分辨显微成像方法 |
| JP2017156694A (ja) * | 2016-03-04 | 2017-09-07 | 株式会社フォブ | 光学顕微鏡、及び観察方法 |
| JP6765648B2 (ja) * | 2016-07-13 | 2020-10-07 | 国立大学法人東京農工大学 | 光検出装置、光検出方法および光検出プログラム |
| US10876892B2 (en) * | 2017-04-28 | 2020-12-29 | Biospex, Inc. | Measuring biological analytes using time-resolved spectroscopy |
| US11035797B2 (en) | 2017-04-28 | 2021-06-15 | Biospex, Inc. | Hybrid time-resolved and time-shifted spectroscopy for measuring biological analytes |
| JP6919887B2 (ja) * | 2017-06-16 | 2021-08-18 | 株式会社四国総合研究所 | ガス濃度計測装置および方法 |
| CN108919472B (zh) * | 2018-09-11 | 2024-07-09 | 中国工程物理研究院材料研究所 | 一种多分光镜式高灵敏度同轴光学镜筒 |
| US10760969B1 (en) | 2019-02-28 | 2020-09-01 | Biospex, Inc. | Fluorescence and systemic noise reduction in time-gated spectroscopy |
| US10881301B2 (en) | 2019-05-07 | 2021-01-05 | Biospex, Inc. | Spatial optimization for measuring biological analytes |
| US11326944B2 (en) | 2019-07-12 | 2022-05-10 | Biospex, Inc. | Wearable spectrometer with filtered sensor |
| US11454540B2 (en) | 2019-07-12 | 2022-09-27 | Biospex, Inc. | Wearable spectroscopy using filtered sensor |
| US11781978B2 (en) * | 2019-08-28 | 2023-10-10 | Nippon Telegraph And Telephone Corporation | Spectroscopic measurement device |
| KR102815383B1 (ko) * | 2019-10-29 | 2025-06-02 | 한국전자통신연구원 | 비동기식 변조 기반 분광 장치 |
| CN112187345B (zh) * | 2020-09-18 | 2021-07-27 | 常州大学 | 一种测量光纤长度的装置和方法 |
| CN112187347B (zh) * | 2020-09-18 | 2022-06-03 | 常州大学 | 一种用于测量光纤长度的装置和方法 |
| WO2023243052A1 (ja) * | 2022-06-16 | 2023-12-21 | 日本電信電話株式会社 | 光源 |
| TWI829373B (zh) * | 2022-09-30 | 2024-01-11 | 國立清華大學 | 同調拉曼顯微系統及其方法 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5923683A (en) * | 1995-02-24 | 1999-07-13 | Nippon Telegraph And Telephone Corporation | Coherent white light source and optical devices therewith |
| US20040109232A1 (en) * | 2002-10-10 | 2004-06-10 | Riza Nabeel Agha | Electronically tunable optical filtering modules |
| JP2009222531A (ja) * | 2008-03-14 | 2009-10-01 | Univ Of Tokyo | 非線形分光計測システム用の光源装置、非線形分光計測システム及び方法 |
| US20100027000A1 (en) * | 2007-10-29 | 2010-02-04 | Dimitry Pestov | Hybrid Technique for Coherent Anti-Stokes/Stokes Raman Spectroscopy |
| US20100110426A1 (en) * | 2008-11-03 | 2010-05-06 | The National Institute Of Standards And Technology | Method for nrb-free nonlinear vibrational spectroscopy and miscroscopy |
| US20100134793A1 (en) * | 2008-11-28 | 2010-06-03 | Leica Microsystems Cms Gmbh | Optical evaluation method by means of laser pulses and corresponding apparatus |
| CN101819064A (zh) * | 2010-05-11 | 2010-09-01 | 哈尔滨工业大学 | 常温常压飞秒cars时间分辨光谱测量系统 |
| US20110164246A1 (en) * | 2008-06-13 | 2011-07-07 | Embl Heidelberg | Next generation flow cytometer sorter |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1237980B (it) * | 1990-02-12 | 1993-06-19 | Pirelli Cavi Spa | Amplificatore ottico a fibra attiva monomodale incurvata |
| JPH05288681A (ja) | 1992-04-13 | 1993-11-02 | Osaka Gas Co Ltd | コヒ−レント反スト−クスラマン散乱分光測定装置 |
| JP3691813B2 (ja) | 2002-07-31 | 2005-09-07 | 独立行政法人科学技術振興機構 | 非線形ラマン分光方法及び装置 |
| EP1754033B1 (en) * | 2004-05-27 | 2011-06-22 | Yeda Research And Development Co., Ltd. | Coherently controlled nonlinear raman spectroscopy |
| US7586618B2 (en) * | 2005-02-28 | 2009-09-08 | The Board Of Trustees Of The University Of Illinois | Distinguishing non-resonant four-wave-mixing noise in coherent stokes and anti-stokes Raman scattering |
| JP4895522B2 (ja) | 2005-03-30 | 2012-03-14 | オリンパス株式会社 | 顕微鏡装置 |
| US7414729B2 (en) * | 2005-10-13 | 2008-08-19 | President And Fellows Of Harvard College | System and method for coherent anti-Stokes Raman scattering endoscopy |
| US7352458B2 (en) * | 2005-10-26 | 2008-04-01 | President And Fellows Of Harvard College | System and method for high sensitivity vibrational imaging with frequency modulation coherent anti-stokes Raman scattering analyses |
| US20100232459A1 (en) * | 2006-05-15 | 2010-09-16 | Mamoru Hashimoto | Pulse Laser Light Timing Adjusting Device, Adjusting Method, and Optical Microscope |
| DE102007048135B4 (de) * | 2007-10-05 | 2012-02-16 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Fluoreszenzlichtmikroskopisches Messen einer Probe mit rotverschobenen Stokes-Linien |
| JP2010002256A (ja) * | 2008-06-19 | 2010-01-07 | Fujifilm Corp | 非線形ラマン散乱光測定装置 |
| US8730469B2 (en) * | 2008-07-17 | 2014-05-20 | Indian Institute Of Science | Method for detecting vibrational structure of a molecule and a system thereof |
| US9285575B2 (en) * | 2009-01-26 | 2016-03-15 | President And Fellows Of Harvard College | Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping |
| US8625091B2 (en) * | 2009-09-30 | 2014-01-07 | Genia Photonics Inc. | Spectrometer |
| JP2011108324A (ja) | 2009-11-18 | 2011-06-02 | Fuji Electric Device Technology Co Ltd | 磁気記録媒体の特性評価方法 |
| DE102010019811A1 (de) * | 2010-05-06 | 2011-11-10 | Airbus Operations Gmbh | Verfahren und Vorrichtung zur Messung der Strömungsgeschwindigkeit mittels eines Plasmas |
| US20120010513A1 (en) * | 2010-07-08 | 2012-01-12 | Wong Stephen T C | Chemically-selective, label free, microendoscopic system based on coherent anti-stokes raman scattering and microelectromechanical fiber optic probe |
| US8928863B2 (en) * | 2011-05-06 | 2015-01-06 | Northrop Grumman Systems Corporation | Systems and methods for generating an optical pulse |
-
2011
- 2011-05-13 JP JP2011108324A patent/JP2012237714A/ja active Pending
-
2012
- 2012-05-01 US US13/460,912 patent/US20120287428A1/en not_active Abandoned
- 2012-05-02 EP EP12003143A patent/EP2522969A3/en not_active Withdrawn
- 2012-05-07 CN CN2012101392896A patent/CN102778448A/zh active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5923683A (en) * | 1995-02-24 | 1999-07-13 | Nippon Telegraph And Telephone Corporation | Coherent white light source and optical devices therewith |
| US20040109232A1 (en) * | 2002-10-10 | 2004-06-10 | Riza Nabeel Agha | Electronically tunable optical filtering modules |
| US20100027000A1 (en) * | 2007-10-29 | 2010-02-04 | Dimitry Pestov | Hybrid Technique for Coherent Anti-Stokes/Stokes Raman Spectroscopy |
| JP2009222531A (ja) * | 2008-03-14 | 2009-10-01 | Univ Of Tokyo | 非線形分光計測システム用の光源装置、非線形分光計測システム及び方法 |
| US20110164246A1 (en) * | 2008-06-13 | 2011-07-07 | Embl Heidelberg | Next generation flow cytometer sorter |
| US20100110426A1 (en) * | 2008-11-03 | 2010-05-06 | The National Institute Of Standards And Technology | Method for nrb-free nonlinear vibrational spectroscopy and miscroscopy |
| US20100134793A1 (en) * | 2008-11-28 | 2010-06-03 | Leica Microsystems Cms Gmbh | Optical evaluation method by means of laser pulses and corresponding apparatus |
| CN101819064A (zh) * | 2010-05-11 | 2010-09-01 | 哈尔滨工业大学 | 常温常压飞秒cars时间分辨光谱测量系统 |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105247350B (zh) * | 2013-03-26 | 2018-04-06 | 艾克斯-马赛大学 | 用于受激拉曼检测的设备和方法 |
| CN105247350A (zh) * | 2013-03-26 | 2016-01-13 | 国家科学研究中心 | 用于受激拉曼检测的设备和方法 |
| CN103280693A (zh) * | 2013-05-27 | 2013-09-04 | 深圳市盛世领航光电有限公司 | 气体rgb激光器和rgb三色激光的发生方法 |
| CN103280693B (zh) * | 2013-05-27 | 2015-06-17 | 深圳市盛世领航光电有限公司 | 气体rgb激光器和rgb三色激光的发生方法 |
| CN105683818A (zh) * | 2013-09-03 | 2016-06-15 | 徕卡显微系统复合显微镜有限公司 | 具有偏振的样品照明的扫描显微镜 |
| CN105683818B (zh) * | 2013-09-03 | 2019-10-22 | 徕卡显微系统复合显微镜有限公司 | 具有偏振的样品照明的扫描显微镜 |
| CN103487146B (zh) * | 2013-09-16 | 2015-06-10 | 华南师范大学 | 一种简便的超宽带受激拉曼光谱显微成像系统 |
| CN103487146A (zh) * | 2013-09-16 | 2014-01-01 | 华南师范大学 | 一种简便的超宽带受激拉曼光谱显微成像系统 |
| CN109075523A (zh) * | 2016-01-22 | 2018-12-21 | 国立科学研究中心 | 用于生成具有基本上恒定的能量的多色光子束的设备 |
| CN107064100A (zh) * | 2016-11-03 | 2017-08-18 | 北京信息科技大学 | 基于色散时变的光纤拉曼光谱仪 |
| CN107064100B (zh) * | 2016-11-03 | 2019-12-27 | 北京信息科技大学 | 基于色散时变的光纤拉曼光谱仪 |
| CN107290056A (zh) * | 2017-06-30 | 2017-10-24 | 中国科学院半导体研究所 | 拉曼光谱测试系统 |
| CN108489959A (zh) * | 2018-03-21 | 2018-09-04 | 中山大学 | 一种相干反斯托克斯拉曼光谱扫描装置和方法 |
| CN109638620A (zh) * | 2018-12-06 | 2019-04-16 | 华南师范大学 | 一种基于掺Yb2+光纤的可见光光纤激光器 |
| CN109687267A (zh) * | 2018-12-06 | 2019-04-26 | 华南师范大学 | 一种用于产生561nm波长的光纤激光器 |
| CN119310726A (zh) * | 2024-12-03 | 2025-01-14 | 浙江大学 | 一种非线性焦点调制显微成像装置及方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2522969A3 (en) | 2013-01-02 |
| JP2012237714A (ja) | 2012-12-06 |
| EP2522969A2 (en) | 2012-11-14 |
| US20120287428A1 (en) | 2012-11-15 |
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Application publication date: 20121114 |