CN102770122A - 双磷酸注射液医药产品及其制法 - Google Patents
双磷酸注射液医药产品及其制法 Download PDFInfo
- Publication number
- CN102770122A CN102770122A CN2010800642022A CN201080064202A CN102770122A CN 102770122 A CN102770122 A CN 102770122A CN 2010800642022 A CN2010800642022 A CN 2010800642022A CN 201080064202 A CN201080064202 A CN 201080064202A CN 102770122 A CN102770122 A CN 102770122A
- Authority
- CN
- China
- Prior art keywords
- parenteral solution
- phosphoric acid
- acid
- bis phosphoric
- glass container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
一种双磷酸注射液医药产品及其制备方法，其包括(a)玻璃容器，以及(b)置于该玻璃容器中的双磷酸注射液，其中该玻璃容器具有接触该双磷酸注射液的表面，所述表而经螯合剂预处理，使得双磷酸注射液具有增进的储存稳定性。
Description
PCT国内申请，说明书已公开。
Claims (1)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2010/000521 WO2011127629A1 (zh) | 2010-04-16 | 2010-04-16 | 双磷酸注射液医药产品及其制法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102770122A true CN102770122A (zh) | 2012-11-07 |
| CN102770122B CN102770122B (zh) | 2013-12-11 |
Family
ID=44798245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800642022A Expired - Fee Related CN102770122B (zh) | 2010-04-16 | 2010-04-16 | 双磷酸注射液医药产品及其制法 |
Country Status (3)
| Country | Link |
|---|---|
| KR (1) | KR20120121403A (zh) |
| CN (1) | CN102770122B (zh) |
| WO (1) | WO2011127629A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797092A (zh) * | 2020-06-16 | 2021-12-17 | 四川远大蜀阳药业有限责任公司 | 稳定小容量玻璃容器装液体制剂的pH值和/或电导率的方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721132B (zh) * | 2013-12-21 | 2018-05-18 | 石药集团恩必普药业有限公司 | 一种唑来膦酸注射液及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5662918A (en) * | 1992-08-27 | 1997-09-02 | Boehringer Mannheim Gmbh | Pharmaceutical agents containing diphosphonic acids and salts thereof |
| US5849095A (en) * | 1996-04-09 | 1998-12-15 | Rouillard; Carol | Anti-etch bottle washing solution |
| CN1441674A (zh) * | 2000-09-18 | 2003-09-10 | 福荷福尔丁和考有限公司 | 二磷酸盐溶液 |
-
2010
- 2010-04-16 CN CN2010800642022A patent/CN102770122B/zh not_active Expired - Fee Related
- 2010-04-16 KR KR1020127023881A patent/KR20120121403A/ko active Search and Examination
- 2010-04-16 WO PCT/CN2010/000521 patent/WO2011127629A1/zh active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5662918A (en) * | 1992-08-27 | 1997-09-02 | Boehringer Mannheim Gmbh | Pharmaceutical agents containing diphosphonic acids and salts thereof |
| US5849095A (en) * | 1996-04-09 | 1998-12-15 | Rouillard; Carol | Anti-etch bottle washing solution |
| CN1441674A (zh) * | 2000-09-18 | 2003-09-10 | 福荷福尔丁和考有限公司 | 二磷酸盐溶液 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113797092A (zh) * | 2020-06-16 | 2021-12-17 | 四川远大蜀阳药业有限责任公司 | 稳定小容量玻璃容器装液体制剂的pH值和/或电导率的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011127629A9 (zh) | 2011-12-29 |
| WO2011127629A1 (zh) | 2011-10-20 |
| CN102770122B (zh) | 2013-12-11 |
| KR20120121403A (ko) | 2012-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131211 Termination date: 20180416 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |