CN102764381B - Traditional Chinese medicine composite for curing cerebral infarction sequelae - Google Patents
Traditional Chinese medicine composite for curing cerebral infarction sequelae Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composite for curing cerebral infarction sequelae, and relates to the technical field of Chinese herbal medicine. The composite comprises, by weight, 15 parts to 25 parts of irkutsk anemone rhizome, 8 parts to 15 parts of pseudo-ginseng, 5 parts to 15 parts of Morinda officinalis, 5 parts to 15 parts of cistanche, 15 to 30 parts of tortoise plastron, 20 parts to 35 parts of calcined dragon teeth, 15 parts to 25 parts of figwort root, 5 parts to 15 parts of leech, 15 parts to 25 parts of zaocys dhumnades, 5 parts to 15 parts of gastrodia elata, 15 parts to 25 parts of kudzuvine roots, 5 parts to 15 parts of earthworm and 10 parts to 20 parts of cassia occidentalis. The traditional Chinese medicine composite for curing cerebral infarction sequele can invigorate qi, activate bleed, eliminate wind and stasis, and dredge collaterals; the curative effect is reliable, no side effect exists for human bodies; the effect of curing cerebral infarction sequela is good; and the curing time is short.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition that is used for the treatment of cerebral infarction sequela.
Background technology
Cerebral infarction sequela referred in cerebral infarction morbidity after 1 year, if also there is the symptoms such as hemiplegia or aphasis or facial hemiparalysis, be just called cerebral infarction sequela, be also called the cerebral infarction sequela phase this period, one convalescent period was compared, and resume speed and degree are slower.Mainly contain hemiplegia (hemiplegia), half side physical handicaps, numb limbs and tense tendons, hemianopsia, aphasia.Or crossed paralysis, contralateral sensory disturbance, ophthalmoplegia externa, nystagmus, dyslalia, aphasis, hypomnesis, facial hemiparalysis, dysphagia, choke food choke water, ataxia, dizziness headache etc.The dysemias such as basic reason is that cerebrovascular inside occurs that blood viscosity is high, blood fat is high, hypertension, blood glucose are high, platelet aggregation, form vascular lesion with atheromatous plaque, the thrombosis being formed by two kinds of pathological changes combined effect results stops up due to cerebral arteries, causes the blood flow of brain part to interrupt and the necrosis of cerebral tissue hypoxic-ischemic.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of can QI invigorating, invigorate blood circulation, dispel the wind, the Chinese medicine composition that is used for the treatment of cerebral infarction sequela of blood stasis dispelling, dredging collateral.
Technical problem to be solved by this invention realizes by the following technical solutions:
A Chinese medicine composition that is used for the treatment of cerebral infarction sequela, is characterized in that: described compositions is made up of the component of following weight portion,
Rhizoma Anemones Altaicae 15-25 part, Radix Notoginseng 8-15 part, Radix Morindae Officinalis 5-15 part, Herba Cistanches 5-15 part, Carapax et Plastrum Testudinis 15-30 part, calcined DENS DRACONIS 20-35 part, Radix Scrophulariae 15-25 part, Radix Cyathulae 10-20 part, Bombyx Batryticatus 15-25 part, Scorpio 5-10 part, Eupolyphaga Seu Steleophaga 5-15 part, Hirudo 5-15 part, Zaocys 15-25 part, Rhizoma Gastrodiae 5-15 part, Radix Puerariae 15-25 part, Pheretima 5-15 part, Semen Cassiae 10-20 part.
Optimum weight part of each component is,
20 parts of Rhizoma Anemones Altaicaes, 12 parts of Radix Notoginseng, 10 parts of Radix Morindae Officinaliss, 10 parts of Herba Cistanches, 20 parts of Carapax et Plastrum Testudiniss, 30 parts of calcined DENS DRACONISs, 20 parts of Radix Scrophulariaes, 15 parts of Radix Cyathulaes, 20 parts of Bombyx Batryticatus, 8 parts of Scorpio, 10 parts of Eupolyphaga Seu Steleophagas, 10 parts of Hirudos, 20 parts of Zaocyss, 10 parts, Rhizoma Gastrodiae, 20 parts of Radix Puerariaes, 10 parts of Pheretimas, 15 parts of Semen Cassiae.
Pharmaceutical analysis
Rhizoma Anemones Altaicae:
[property of medicine] is pungent, tepor.GUIXIN, liver, spleen channel.
[effect] has one's ideas straightened out, and eliminating phlegm is regulated the flow of vital energy, and invigorates blood circulation, loose wind, and damp eliminating, is amusing, removing toxic substances.
[pharmacological action] sedation; Analgesic activity; Toxic action.
Radix Notoginseng:
[property of medicine] is warm in nature, sweet in the mouth, micro-hardship, nontoxic.Return liver, stomach warp.
[effect] removing stasis to stop bleeding, promoting blood circulation and stopping pain.
[pharmacological action] hemostasis, antithrombotic, promotion hemopoietic, effect, antiinflammatory to cardiovascular system, protect the liver, antitumor, analgesia.
Radix Morindae Officinalis:
[property of medicine] acrid in the mouth, sweet, slightly warm in nature.Return kidney, Liver Channel.
[effect] reinforcing the kidney and supporting YANG, expelling wind and removing dampness, strengthening the tendons and bones.
[pharmacological action] puts on weight and resisting fatigue; Radix Morindae Officinalis, by suppressing mouse thymus atrophy and increasing leukocyte count in its blood, impacts immunologic function; Radix Morindae Officinalis extract has the effect that increases corticosterone content in blood; There is certain hypotensive effect, but it is short to hold time, and has certain stable and diuresis; There is certain antiinflammatory action.
Herba Cistanches:
[property of medicine] feeble QI, sweet, the micro-hardship of taste.Return kidney, large intestine channel.
[effect] kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.
[pharmacological action] anti-aging effects; Adjust endocrine, promote metabolism and strong effect; Strengthen autoimmunity; Promote the synthetic of deoxysaccharide nucleic acid; Hypotensive effect; Promote salivation and respiratory paralysis effect.
Carapax et Plastrum Testudinis:
[property of medicine] is salty sweet, flat.Enter the heart, spleen, liver three warps.
[effect] YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.
[pharmacological action], by improving the phagocytic function of reticuloendothelial system, significantly increases phagocytic index and engulfs coefficient, also has the effect that makes spleen, thymus weightening finish, and the tip leukopenia that cyclophosphamide is caused has certain protective effect.Strengthen autoimmune function; Improve body antineoplastic immunocompetence; There is to excitation in uterus, can makes uterine contraction strengthen; Significantly strengthen hypoxia-bearing capability under normal pressure.
Calcined DENS DRACONIS:
[property of medicine] is puckery; Sweet; Cool.GUIXIN warp, Liver Channel.
[effect] tranquillizing the mind by relieving convulsion; Clearing heat and relieving fidgetness.
[pharmacological action] tranquilizing mind.
Radix Scrophulariae:
[property of medicine] sweet in the mouth, hardship, salty, cold nature.Return lung, stomach, kidney channel.
[effect] clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
[pharmacological action] Radix Scrophulariae fluid extract trace has slight cardiotonic, and dosage greatly makes heart be intoxicating phenomenon; Hypotensive effect; Antibacterial action; Hypoglycemic activity.
Radix Cyathulae:
[property of medicine] sweet, micro-hardship, flat.Return liver, kidney channel.
[effect] eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.
[pharmacological action] rheumatism lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea.
Bombyx Batryticatus:
[property of medicine] is salty, pungent, flat.Gui Jing, spleen channel.
[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., dispelling wind and heat pathogens, dissipating phlegm and resolving masses.
[pharmacological action] is calm, convulsion; Water extract-alcohol precipitation liquid vivo and vitro all has blood coagulation resisting function; Alloxan-diabetes pancreatic cell is had to repair, to artificial diabetes treatment effectively; Can suppress the growth of ehrlich carcinoma, the growth that Bombyx Batryticatus liquid can suppress sarcoma S180; Various pathogens is had to weak inhibitory action.
Scorpio:
[property of medicine] is pungent, flat, poisonous.Return Liver Channel.
[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.
[pharmacological action] anticonvulsant action; Antiepileptic action; Scorpion venom can make heart contraction tension force strengthen, and peripheral vessel shrinks; Cranial nerve cell structure of mitochondria and function are had to significant impact; Antitumor action.
Eupolyphaga Seu Steleophaga:
[property of medicine] is salty, cold, slightly poisonous.Return Liver Channel.
[effect] removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.
[pharmacological action] extracting solution and water extract-alcohol precipitation liquid are formed and thrombolytic effect by antithrombotic respectively; Extract can anticoagulant and adhesion rate, reduces aggregation number; Total alkaloids can improve cardiac muscle and the tolerance of brain to ischemia, and reduces the oxygen consumption of the heart, cerebral tissue; Decocting liquid has the effect of the fat of tune, can delay atherosclerotic formation; Extract can suppress the hepatic injury due to D-galactose and have hepatoprotective effect.
Hirudo:
[property of medicine] is salty, bitter, flat; Slightly poisonous.Return Liver Channel.
[effect] removing blood stasis, removing blood stasis, stimulates the menstrual flow.
[pharmacological action] anticoagulation and anti thrombotic action; Blood fat reducing; Promote the absorption of Laboratory brain blood swelling and ecchymosis; By termination of pregnancy, antiearly pregnancy effect; Hirudin can be to the contractile force potentiation due to antithrombase; Hirudo also can secrete a kind of H-subst, expansion blood capillary and increase hemorrhage.
Zaocys:
[property of medicine] is sweet, flat.Return Liver Channel.
[effect] dispels the wind, dredging collateral, arresting convulsion.
[pharmacological action] Zaocys decocting liquid and alcohol extract have antiinflammatory, calmness, analgesic activity; Its serum has the effect of antagonism agkistrodon acutus venom.
Rhizoma Gastrodiae:
[property of medicine] is sweet, flat.Return Liver Channel.
[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.
[pharmacological action] analgesic activity; Sedation, can suppress the central excitation effect due to caffeine, strengthens the length of one's sleep of pentobarbital sodium; Convulsion, has certain curative effect to facial nerve tics, numb limbs and tense tendons, hemiplegia, epilepsy etc., alleviates in addition the effect of smooth muscle spasm, allevating angina pectoris, biliary colic; Treatment hypertension, can increase periphery and coronary artery blood flow, and heart is had to protective effect; People's cerebral nervous system is had to the effect of obvious protection scalable, can strengthen the resolution capability of optic nerve, play the effect of improving eyesight, increasing intelligence.
Radix Puerariae:
[property of medicine] is cool in nature, sweet in the mouth, pungent.
[effect] induced sweat and brought down a fever, promote the production of body fluid, and rash, yang invigorating antidiarrheal.
The flavone proposing in [pharmacological action] Radix Puerariae can increase brain and crown vascular flow amount; Spasmolysis; Hypoglycemic activity; Antipyretic and estrogen-like effects.
Pheretima:
[property of medicine] is salty-cold.
[effect] heat clearing away, spasmolytic, diuresis, removing toxic substances.
[pharmacological action] thrombolytic and anticoagulation; Arrhythmia, blood pressure lowering; Central nervous system is had to treatment cerebral infarction (apoplexy), convulsion and sedation, refrigeration function; Antitumaous effect; Promote smooth muscle contraction; Extract has necessarily antibacterial, external quick spermicide effect; Extract has the collagenase of specificity degrade collagen fiber, and external is effective to local scleroderma.
Semen Cassiae:
[property of medicine] sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.
[effect] clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.
[pharmacological action] antibacterial action: Semen Cassiae alcohol extract all has inhibitory action to staphylococcus, diphtheria corynebacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, water extract is invalid.Antifungal: water logging agent tube dilution method, 1:20 is to microsporon audouini, and 1:10 is all had inhibitory action to permitting blue achorion and microsporon gypseum.Blood pressure lowering: water logging agent and ethanol immersion have hypotensive effect.Blood fat reducing: Semen Cassiae decoct or Trial On The Action of Semen Cassiae Powder can reduce blood plasma ornitrol, triglyceride, the content of triglyceride in reduction gallbladder.Antiplatelet aggregation: Semen Cassiae decoct or powder have inhibitory action to the platelet aggregation of ADP induction.
Usage and dosage:
Each taste medicine is ground as smalls, and mix homogeneously, adds Mel 100g, is combined into ball.Each serving 40g, three times on the one two months is a course for the treatment of, and cure general 2-3 the course for the treatment of.
The invention has the beneficial effects as follows: the present invention can QI invigorating, invigorate blood circulation, dispel the wind, blood stasis dispelling, dredging collateral, and curative effect is reliable, and health is had no side effect, and treatment cerebral infarction sequela is effective, and healing time is short.
Detailed description of the invention
For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.
Embodiment 1
Take Rhizoma Anemones Altaicae 20g, Radix Notoginseng 12g, Radix Morindae Officinalis 10g, Herba Cistanches 10g, Carapax et Plastrum Testudinis 20g, calcined DENS DRACONIS 30g, Radix Scrophulariae 20g, Radix Cyathulae 15g, Bombyx Batryticatus 20g, Scorpio 8g, Eupolyphaga Seu Steleophaga 10g, Hirudo 10g, Zaocys 20g, Rhizoma Gastrodiae 10g, Radix Puerariae 20g, Pheretima 10g, Semen Cassiae 15g.
Each taste medicine is ground as smalls, and mix homogeneously, adds Mel 100g, is combined into ball.Each serving 40g, three times on the one two months is a course for the treatment of, and cure general 2-3 the course for the treatment of.
Embodiment 2
High big vast woods man 51 years old is medical because of " dizzy, left side upper and lower extremities is unable, companion's dysfunction 2 hours ", when patient worked before 2 hours, occur dizzy, left side upper and lower extremities is unable, accompanies dysfunction, then to our hospital.
Have a medical check-up:
Measuring blood pressure: 160/110mmHg, bicker, without crooked, lolls placed in the middle, and bilateral eyelid is without sagging, freely, the circle such as bilateral isocoria, exists luminous reflectance in ocular movemeut, and corneal reflex is normal, bilateral nasolabial fold is without shoaling, left side upper and lower extremities muscular strength, hypomyotonia, 2 grades of muscular strengths.Left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex slightly weaken, left side Babinski levies, Chaddock levies (+), bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender, flatcar pushes ward, head CT checks: right side lacunar infarction, intend hospitalizing and being admitted to hospital with " right side lacunar infarction ".
While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, and 2 times/day, sooner or later respectively take 1 time, 14 days courses for the treatment of, and advise functional exercise.
After 1 month, patient is without a head dizzy, and the unable and dysfunction of suffering limb is clearly better.After continuing to take medicine 2 months, left side upper and lower extremities muscular strength, muscular tension slightly weaken, 4 grades of muscular strengths, and left hand held object is accessible, and walking step state is steady.After 5 months, patient recovers normal.
Embodiment 3
Zhang Guoying man 40 years old goes to a doctor because of " dizziness, companion left side upper and lower extremities carries out sexual dysfunction, unable 5 days ".Patient occurred dizzy in the time having supper before 5 days, companion left side upper and lower extremities carries out sexual dysfunction, unable; Then arrive the People's Hospital of Jieshou City city medical, wardrobe cranium CT examination is: multiple lacuna cerebral infarction, give the Drug therapys such as DANHONG, mannitol, calf blood protein-removed extraction, and symptom has no alleviation; Modern is further treatment, then to our hospital, have a medical check-up: right side eyesight weaken, left side upper and lower extremities muscular strength, muscular tension obviously weaken, 3 grades of muscular strengths, left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex weaken, and left side Babinski levies, Chaddock levies (+), and bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender.Intend hospitalizing and being admitted to hospital with " multiple lacuna cerebral infarction ".
While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, respectively takes 1 time 14 days courses for the treatment of sooner or later.And advise functional exercise.
After 2 months, patient is without a head dizzy, and the unable and dysfunction of suffering limb is clearly better.After continuing to take medicine 4 months, left side upper and lower extremities muscular strength, muscular tension slightly weaken, 4 grades of muscular strengths, and left hand held object is accessible, and walking step state is steady.After 6 months, patient recovers normal.
Embodiment 4
Stone osmanthus English female 71 years old because of " more than dysphonia, left side upper and lower extremities dysfunction January; increase the weight of 2 days " medical, before patient January, get up and while cooking, occur carrying out that language is unfavorable, left side upper and lower extremities dysfunction morning, to the People's Hospital of city, medical head CT shows right side cerebral infarction, with right side cerebral infarction hospitalization, give blood circulation promoting and blood stasis dispelling and oral drugs (concrete medicine is not quite clear) treatment, symptom has no alleviation; Then to our hospital after being introduced, outpatient service is intended hospitalizing and being admitted to hospital with right side cerebral infarction, gives blood circulation promoting and blood stasis dispelling and short cerebral cell recovery medicine (cerebrolysin, born of the same parents' two phosphorus, SHUXUENING etc.) treatment, and above-mentioned symptom is left hospital after taking a turn for the better.Before 2 days, patient increases the weight of because of excited above-mentioned symptom, then to our hospital, outpatient service is had a medical check-up: bicker is crooked to the right, loll crooked left, left side upper and lower extremities muscular strength, muscular tension obviously weaken, 2 grades of muscular strengths, left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex weaken, left side Babinski levies (+), and Chaddock levies (+-), and bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender; Outpatient service is intended hospitalizing and being admitted to hospital with " right side cerebral infarction ".
While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, respectively takes 1 time 14 days courses for the treatment of sooner or later.And advise functional exercise.
After 1 month, patient is without dysphonia, and the unable and dysfunction of suffering limb takes a turn for the better.After continuing to take medicine 3 months, left side upper and lower extremities muscular strength, muscular tension slightly weaken, 4 grades of muscular strengths, and left hand held object obstacle is clearly better, and walking step state is slightly not steady.After 6 months, patient recovers normal.
Embodiment 5
Zhang Huazhou man 82 years old is medical because of " dizzy, left side upper and lower extremities is unable, companion's dysfunction 5 days ", when patient had a meal before 5 days, occur dizzy, left side upper and lower extremities is unable, accompanies dysfunction; Medical at village's clinic, to intend giving the Drug therapy such as blood circulation promoting and blood stasis dispelling and blood vessel dilating with cerebral infarction, symptom has no improvement; Modern to our hospital, outpatient service is had a medical check-up: measuring blood pressure: 160/90mmHg, bicker is without crooked, bilateral nasolabial fold is without shoaling, loll placed in the middle, instability of gait, biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex (+-), left side upper and lower extremities muscular strength, hypomyotonia, 3 grades of muscular strengths.Left side Babinski levies, Chaddock levies (+), and Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender, and wardrobe cranium CT examination is: multiple cerebral infarction; Outpatient service is intended hospitalizing and being admitted to hospital with " multiple cerebral infarction " " hypertension (II level) ".
While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, respectively takes 1 time 14 days courses for the treatment of sooner or later.And advise functional exercise.
1 month future trouble myasthenia of limbs and dysfunction take a turn for the better.After continuing to take medicine 3 months, left side upper and lower extremities muscular strength, muscular tension slightly weaken, 4 grades of muscular strengths, and left hand held object obstacle is clearly better, and walking step state is slightly not steady.After 6 months, patient recovers normal.
More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.
Claims (2)
1. a Chinese medicine composition that is used for the treatment of cerebral infarction sequela, is characterized in that: described compositions is made up of the component of following weight portion,
Rhizoma Anemones Altaicae 15-25 part, Radix Notoginseng 8-15 part, Radix Morindae Officinalis 5-15 part, Herba Cistanches 5-15 part, Carapax et Plastrum Testudinis 15-30 part, calcined DENS DRACONIS 20-35 part, Radix Scrophulariae 15-25 part, Radix Cyathulae 10-20 part, Bombyx Batryticatus 15-25 part, Scorpio 5-10 part, Eupolyphaga Seu Steleophaga 5-15 part, Hirudo 5-15 part, Zaocys 15-25 part, Rhizoma Gastrodiae 5-15 part, Radix Puerariae 15-25 part, Pheretima 5-15 part, Semen Cassiae 10-20 part, each taste medicine is ground as smalls, mix homogeneously, adds Mel and is combined into ball.
2. a kind of Chinese medicine composition that is used for the treatment of cerebral infarction sequela according to claim 1, is characterized in that: described compositions is made up of the component of following weight portion,
20 parts of Rhizoma Anemones Altaicaes, 12 parts of Radix Notoginseng, 10 parts of Radix Morindae Officinaliss, 10 parts of Herba Cistanches, 20 parts of Carapax et Plastrum Testudiniss, 30 parts of calcined DENS DRACONISs, 20 parts of Radix Scrophulariaes, 15 parts of Radix Cyathulaes, 20 parts of Bombyx Batryticatus, 8 parts of Scorpio, 10 parts of Eupolyphaga Seu Steleophagas, 10 parts of Hirudos, 20 parts of Zaocyss, 10 parts, Rhizoma Gastrodiae, 20 parts of Radix Puerariaes, 10 parts of Pheretimas, 15 parts of Semen Cassiae, each taste medicine is ground as smalls, mix homogeneously, adds Mel and is combined into ball.
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| CN104189738A (en) * | 2014-08-12 | 2014-12-10 | 黄太锋 | Traditional Chinese medicine composition for treating sequel of cerebral infarction |
| CN106902261A (en) * | 2017-02-14 | 2017-06-30 | 四川双鑫生物科技有限公司 | A kind of pill medicine and preparation method that can effectively treat sequelae for cerebral infraction |
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