CN102764381A - Traditional Chinese medicine composite for curing cerebral infarction sequelae - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composite for curing cerebral infarction sequelae, and relates to the technical field of Chinese herbal medicine. The composite comprises, by weight, 15 parts to 25 parts of irkutsk anemone rhizome, 8 parts to 15 parts of pseudo-ginseng, 5 parts to 15 parts of Morinda officinalis, 5 parts to 15 parts of cistanche, 15 to 30 parts of tortoise plastron, 20 parts to 35 parts of calcined dragon teeth, 15 parts to 25 parts of figwort root, 5 parts to 15 parts of leech, 15 parts to 25 parts of zaocys dhumnades, 5 parts to 15 parts of gastrodia elata, 15 parts to 25 parts of kudzuvine roots, 5 parts to 15 parts of earthworm and 10 parts to 20 parts of cassia occidentalis. The traditional Chinese medicine composite for curing cerebral infarction sequele can invigorate qi, activate bleed, eliminate wind and stasis, and dredge collaterals; the curative effect is reliable, no side effect exists for human bodies; the effect of curing cerebral infarction sequela is good; and the curing time is short.

Description

A kind of Chinese medicine composition that is used to treat cerebral infarction sequela

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition that is used to treat cerebral infarction sequela.

Background technology

Cerebral infarction sequela is meant in the cerebral infarction morbidity after 1 year; If also there are symptoms such as hemiplegia or aphasis or facial hemiparalysis, just be called cerebral infarction sequela, also be called the cerebral infarction sequela phase this period; One convalescent period was compared, and resume speed and degree are slower.Mainly contain hemiplegia (hemiplegia), half side physical handicaps, numb limbs and tense tendons, hemianopsia, aphasia.Perhaps crossed paralysis, contralateral sensory disturbance, ophthalmoplegia externa, nystagmus, dyslalia, aphasis, hypomnesis, facial hemiparalysis, dysphagia, choke food choke water, ataxia, dizziness headache etc.Basic reason is that dysemias such as blood viscosity height, blood fat height, hypertension, blood glucose height, platelet aggregation appear in cerebrovascular inside; Form vascular lesion with atheromatous plaque; The thrombosis that is formed by two kinds of pathological changes combined effect results stops up due to the cerebral arteries, causes the partial blood flow of brain to interrupt and the necrosis of cerebral tissue hypoxic-ischemic.

Summary of the invention

Technical problem to be solved by this invention be to provide a kind of can QI invigorating, invigorate blood circulation, dispel the wind, the Chinese medicine composition that is used to treat cerebral infarction sequela of blood stasis dispelling, collateral dredging.

Technical problem to be solved by this invention adopts following technical scheme to realize:

A kind of Chinese medicine composition that is used to treat cerebral infarction sequela is characterized in that: described compositions is made up of the component of following weight portion,

Rhizoma Anemones Altaicae 15-25 part, Radix Notoginseng 8-15 part, Radix Morindae Officinalis 5-15 part, Herba Cistanches 5-15 part, Carapax et Plastrum Testudinis 15-30 part, calcined DENS DRACONIS 20-35 part, Radix Scrophulariae 15-25 part, Radix Cyathulae 10-20 part, Bombyx Batryticatus 15-25 part, Scorpio 5-10 part, Eupolyphaga Seu Steleophaga 5-15 part, Hirudo 5-15 part, Zaocys 15-25 part, Rhizoma Gastrodiae 5-15 part, Radix Puerariae 15-25 part, Pheretima 5-15 part, Semen Cassiae 10-20 part.

Optimum weight part of each component does,

20 parts of Rhizoma Anemones Altaicaes, 12 parts of Radix Notoginseng, 10 parts of Radix Morindae Officinaliss, 10 parts of Herba Cistanches, 20 parts of Carapax et Plastrum Testudiniss, 30 parts of calcined DENS DRACONISs, 20 parts of Radix Scrophulariaes, 15 parts of Radix Cyathulaes, 20 parts of Bombyx Batryticatus, 8 parts of Scorpio, 10 parts of Eupolyphaga Seu Steleophagas, 10 parts of Hirudos, 20 parts of Zaocyss, 10 parts in Rhizoma Gastrodiae, 20 parts of Radix Puerariaes, 10 parts of Pheretimas, 15 parts of Semen Cassiae.

Pharmaceutical analysis

Rhizoma Anemones Altaicae:

[property of medicine] suffering, tepor.GUIXIN, liver, spleen channel.

[effect] has one's ideas straightened out, and eliminating phlegm is regulated the flow of vital energy, and invigorates blood circulation, the wind that looses, and damp eliminating is amusing, detoxifcation.

[pharmacological action] sedation; Analgesic activity; Toxic action.

Radix Notoginseng:

[property of medicine] is warm in nature, sweet in the mouth, little hardship, nontoxic.Return liver, stomach warp.

[effect] removing stasis to stop bleeding, promoting blood circulation and stopping pain.

[pharmacological action] hemostasis, antithrombotic, promotion hemopoietic, the effect to cardiovascular system, antiinflammatory, protect the liver, antitumor, analgesia.

Radix Morindae Officinalis:

[property of medicine] acrid in the mouth, sweet, slightly warm in nature.Return kidney, Liver Channel.

[effect] reinforcing the kidney and supporting YANG, expelling wind and removing dampness, strengthening the tendons and bones.

[pharmacological action] weight increase and resisting fatigue; Radix Morindae Officinalis impacts immunologic function through suppressing the mouse thymus atrophy and increasing leukocyte count in its blood; Radix Morindae Officinalis extract has the effect that increases corticosterone content in the blood; Have certain hypotensive effect, but the weak point of holding time, and certain stable and diuresis is arranged; Has certain antiinflammatory action.

Herba Cistanches:

[property of medicine] feeble QI, sweet, little hardship of distinguishing the flavor of.Return kidney, large intestine channel.

[effect] kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.

[pharmacological action] anti-aging effects; Adjustment endocrine, promotion metabolism and strong effect; Strengthen autoimmunity; Promote the synthetic of deoxysaccharide nucleic acid; Hypotensive effect; Promote salivation and respiratory paralysis effect.

Carapax et Plastrum Testudinis:

[property of medicine] is salty sweet, and is flat.Go into the heart, spleen, liver three warps.

[effect] YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.

[pharmacological action] significantly increases phagocytic index and engulfs coefficient through improving the phagocytic function of reticuloendothelial system, and the effect that makes spleen, thymus weightening finish is also arranged, and the tip leukopenia that cyclophosphamide is caused has the certain protection effect.Strengthen autoimmune function; Improve body antineoplastic immunocompetence; The uterus there is excitation, uterine contraction is strengthened; Significantly strengthen hypoxia-bearing capability under the normal pressure.

Calcined DENS DRACONIS:

[property of medicine] is puckery; Sweet; Cool.GUIXIN warp, Liver Channel.

[effect] tranquillizing the mind by relieving convulsion; Clearing heat and relieving fidgetness.

[pharmacological action] tranquilizing mind.

Radix Scrophulariae:

[property of medicine] sweet in the mouth, hardship, salty, cold nature.Return lung, stomach, kidney channel.

[effect] clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.

[pharmacological action] Radix Scrophulariae fluid extract trace has slight cardiotonic, and dosage greatly then makes heart be intoxicating phenomenon; Hypotensive effect; Antibacterial action; Hypoglycemic activity.

Radix Cyathulae:

[property of medicine] sweet, little hardship, flat.Return liver, kidney channel.

[effect] eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.

[pharmacological action] rheumatism lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea.

Bombyx Batryticatus:

[property of medicine] is salty, hot, flat.Gui Jing, spleen channel.

[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., dispelling wind and heat pathogens, dissipating phlegm and resolving masses.

[pharmacological action] is calm, convulsion; External in the water extract-alcohol precipitation liquid all have a blood coagulation resisting function; Alloxan type diabetic pancreas cell there is repair, effectively to the artificial diabetes treatment; Can suppress the growth of ehrlich carcinoma, the growth that Bombyx Batryticatus liquid can suppress sarcoma S180; Various pathogens there is weak inhibitory action.

Scorpio:

[property of medicine] is hot, flat, poisonous.Return Liver Channel.

[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.

[pharmacological action] anticonvulsant action; Antiepileptic action; Scorpion venom can make heart contraction tension force strengthen, and peripheral vessel shrinks; Cranial nerve cell structure of mitochondria and function had remarkable influence; Antitumor action.

Eupolyphaga Seu Steleophaga:

[property of medicine] is salty, cold, slightly poisonous.Return Liver Channel.

[effect] removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.

[pharmacological action] extracting solution and water extract-alcohol precipitation liquid are formed and thrombolytic effect by antithrombotic respectively; But extract anticoagulant and adhesion rate reduce aggregation number; Total alkaloids can improve cardiac muscle and brain to the tolerance of ischemia, and the oxygen consumption of the reduction heart, cerebral tissue; Decocting liquid has the effect of the fat of accent, can delay atherosclerotic formation; Extract can suppress the hepatic injury due to the D-galactose and hepatoprotective effect is arranged.

Hirudo:

[property of medicine] is salty, bitter, and is flat; Slightly poisonous.Return Liver Channel.

[effect] removing blood stasis, removing blood stasis stimulates the menstrual flow.

[pharmacological action] anticoagulation and anti thrombotic action; Blood fat reducing; Promote the absorption of experimental cephalophyma and ecchymosis; By termination of pregnancy, antiearly pregnancy effect; Hirudin can be to the heart contractility potentiation due to the antithrombase; Hirudo also can secrete a kind of H-subst, expansion blood capillary and increase hemorrhage.

Zaocys:

[property of medicine] is sweet, and is flat.Return Liver Channel.

[effect] dispels the wind, collateral dredging, arresting convulsion.

[pharmacological action] Zaocys decocting liquid and alcohol extract have antiinflammatory, calmness, analgesic activity; Its serum has the effect of antagonism agkistrodon acutus venom.

Rhizoma Gastrodiae:

[property of medicine] is sweet, and is flat.Return Liver Channel.

[effect] spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral.

[pharmacological action] analgesic activity; Sedation can suppress the central excitation effect due to the caffeine, strengthens the length of one's sleep of pentobarbital sodium; Convulsion has certain curative effect to facial nerve tics, numb limbs and tense tendons, hemiplegia, epilepsy etc., alleviates the effect of smooth muscle spasm, allevating angina pectoris, biliary colic in addition; Treatment hypertension can increase periphery and crown blood flow volume, and heart is had protective effect; Cerebral nervous system to the people has the effect of significant protection scalable, can strengthen the resolution capability of optic nerve, plays the effect that makes eye bright, increases intelligence.

Radix Puerariae:

[property of medicine] is cool in nature, sweet in the mouth, suffering.

[effect] induced sweat and brought down a fever, and promotes the production of body fluid rash, yang invigorating antidiarrheal.

The flavone that proposes in [pharmacological action] Radix Puerariae can increase brain and crown vascular flow amount; Spasmolysis; Hypoglycemic activity; Analgesic and estrogen-like effects.

Pheretima:

[property of medicine] is salty-cold.

[effect] heat clearing away, spasmolytic, diuresis, detoxifcation.

[pharmacological action] thrombolytic and anticoagulation; Arrhythmia, blood pressure lowering; The central nervous system had treatment cerebral infarction (apoplexy), convulsion and sedation, refrigeration function; Antitumaous effect; Promote smooth muscle contraction; Extract has necessarily antibiotic, external quick spermicide effect; Extract has the collagenase of specificity degrade collagen fiber, and external is effective to local scleroderma.

Semen Cassiae:

[property of medicine] sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.

[effect] clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.

[pharmacological action] antibacterial action: the Semen Cassiae alcohol extract all has inhibitory action to staphylococcus, diphtheria corynebacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, and water extract is then invalid.Antifungal: tube dilution method is used in the water logging agent, and 1:20 is to microsporon audouini, and 1:10 is all had inhibitory action to permitting blue achorion and microsporon gypseum.Blood pressure lowering: water logging agent and ethanol immersion have hypotensive effect.Blood fat reducing: Semen Cassiae decoct or Semen Cassiae powder can reduce blood plasma ornitrol, triglyceride, reduce the content of triglyceride in the gallbladder.Antiplatelet aggregation: Semen Cassiae decoct or powder have inhibitory action to the inductive platelet aggregation of ADP.

Usage and dosage:

Each flavor medicine is ground and is smalls, and mix homogeneously adds Mel 100g, is combined into ball.Each clothes 40g, three times on the one, two months is a course of treatment, cure general 2-3 the course of treatment.

The invention has the beneficial effects as follows: the present invention can QI invigorating, invigorate blood circulation, dispel the wind, blood stasis dispelling, collateral dredging, and curative effect is reliable, and health is had no side effect, and the treatment cerebral infarction sequela is effective, and healing time is short.

The specific embodiment

For technological means, creation characteristic that the present invention is realized, reach purpose and effect and be easy to understand and understand, below in conjunction with specific embodiment, further set forth the present invention.

Embodiment 1

Take by weighing Rhizoma Anemones Altaicae 20g, Radix Notoginseng 12g, Radix Morindae Officinalis 10g, Herba Cistanches 10g, Carapax et Plastrum Testudinis 20g, calcined DENS DRACONIS 30g, Radix Scrophulariae 20g, Radix Cyathulae 15g, Bombyx Batryticatus 20g, Scorpio 8g, Eupolyphaga Seu Steleophaga 10g, Hirudo 10g, Zaocys 20g, Rhizoma Gastrodiae 10g, Radix Puerariae 20g, Pheretima 10g, Semen Cassiae 15g.

Each flavor medicine is ground and is smalls, and mix homogeneously adds Mel 100g, is combined into ball.Each clothes 40g, three times on the one, two months is a course of treatment, cure general 2-3 the course of treatment.

Embodiment 2

High big vast woods man 51 years old goes to a doctor because of " dizzy, the left side upper and lower extremities is unable, companion's dysfunction 2 hours ", occur when the patient worked before 2 hours dizzy, the left side upper and lower extremities is unable, companion's dysfunction is satisfied and is come my institute's prescription on individual diagnosis.

Have a medical check-up:

Measuring blood pressure: 160/110mmHg, bicker does not have crooked, and it is placed in the middle to loll, and the bilateral eyelid does not have sagging; Ocular movemeut freely, bilateral isocoria etc. circles, light reflex exists, corneal reflex is normal; The bilateral nasolabial fold does not have and shoals left side upper and lower extremities muscular strength, hypomyotonia, 2 grades of muscular strengths.Left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex weaken slightly; Left side Babinski levies, Chaddock levies (+); Bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender; Flatcar pushes the ward, the head CT inspection: the right side lacunar infarction, and intend and hospitalize and be admitted to hospital with " right side lacunar infarction ".

While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, and 2 times/day, sooner or later respectively obey 1 time, 14 days one courses of treatment, and advise functional exercise.

The patient is without a head dizzy after 1 month, suffers from myasthenia of limbs and dysfunction and is clearly better.Left side upper and lower extremities muscular strength, muscular tension have slightly and weaken after continuing to take medicine 2 months, 4 grades of muscular strengths, and left hand held object is accessible, and walking step state is steady.The patient recovers normal after 5 months.

Embodiment 3

Zhang Guoying man 40 years old is because of " dizziness, companion left side upper and lower extremities carry out sexual dysfunction, unable 5 days " prescription on individual diagnosis.The patient occurred dizzy when having supper before 5 days, companion left side upper and lower extremities carries out sexual dysfunction, unable; Satisfy to the People's Hospital, Jieshou City city and go to a doctor, wardrobe cranium CT examination is: multiple lacuna property cerebral infarction, give Drug therapys such as DANHONG, mannitol, calf blood protein-removed extraction, and symptom does not slow and separates; Modern is further treatment; Satisfy and come me institute to go to a doctor, have a medical check-up: the right side vision weakens, and left side upper and lower extremities muscular strength, muscular tension obviously weaken; 3 grades of muscular strengths; Left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex weaken, and left side Babinski levies, Chaddock levies (+), and bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender.Plan is hospitalized and is admitted to hospital with " multiple lacuna property cerebral infarction ".

While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, sooner or later respectively obeys 14 days one courses of treatment 1 time.And advise functional exercise.

The patient is without a head dizzy after 2 months, suffers from myasthenia of limbs and dysfunction and is clearly better.Left side upper and lower extremities muscular strength, muscular tension have slightly and weaken after continuing to take medicine 4 months, 4 grades of muscular strengths, and left hand held object is accessible, and walking step state is steady.The patient recovers normal after 6 months.

Embodiment 4

Stone osmanthus English woman 71 years old is because of " dysphonia, left side upper and lower extremities dysfunction are surplus January; increased the weight of 2 days " prescription on individual diagnosis; The patient before January morning get up and occur when cooking carrying out that language is unfavorable, left side upper and lower extremities dysfunction, show the right side cerebral infarction to the People's Hospital, city prescription on individual diagnosis head CT, with right side cerebral infarction hospitalization; Give blood circulation promoting and blood stasis dispelling and oral drugs (concrete medicine is not quite clear) treatment, symptom does not slow and separates; After satisfy upon somebody's introduction and come my institute to go to a doctor, outpatient service is intended hospitalizing with the right side cerebral infarction and is admitted to hospital, and gives blood circulation promoting and blood stasis dispelling and short cerebral cell recovery medicine (cerebrolysin, born of the same parents' two phosphorus, SHUXUENING etc.) treatment, above-mentioned symptom is left hospital after taking a turn for the better.The patient satisfies and comes me institute to go to a doctor because of excited above-mentioned symptom increases the weight of before 2 days, and outpatient service is had a medical check-up: bicker is crooked to the right; It is crooked left to loll, and left side upper and lower extremities muscular strength, muscular tension obviously weaken, 2 grades of muscular strengths; Left side biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex weaken; Left side Babinski levies (+), and Chaddock levies (+-), and bilateral Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender; Outpatient service is intended and is hospitalized and be admitted to hospital with " right side cerebral infarction ".

While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, sooner or later respectively obeys 14 days one courses of treatment 1 time.And advise functional exercise.

The patient does not have dysphonia after 1 month, suffers from myasthenia of limbs and dysfunction and takes a turn for the better.Left side upper and lower extremities muscular strength, muscular tension have slightly and weaken after continuing to take medicine 3 months, 4 grades of muscular strengths, and left hand held object obstacle is clearly better, and walking step state has not steady slightly.The patient recovers normal basically after 6 months.

Embodiment 5

Zhang Huazhou man 82 years old goes to a doctor because of " dizzy, the left side upper and lower extremities is unable, companion's dysfunction 5 days ", occur when the patient had a meal before 5 days dizzy, the left side upper and lower extremities is unable, accompanies dysfunction; Clinic is gone to a doctor in the village, intends and gives Drug therapys such as blood circulation promoting and blood stasis dispelling and blood vessel dilating with cerebral infarction, the symptom commentaries on classics of not getting better; The present, my institute went to a doctor, and outpatient service is had a medical check-up: measuring blood pressure: 160/90mmHg, and bicker does not have crooked; The bilateral nasolabial fold does not have and shoals; It is placed in the middle to loll, instability of gait, biceps tendon, triceps tendon, radial periosteal reflex, knee jerk, ankle tendon reflex (+-); Left side upper and lower extremities muscular strength, hypomyotonia, 3 grades of muscular strengths.Left side Babinski levies, Chaddock levies (+), and Oppenheim levies, Hoffmann levies, Gordon levies, Lasegue levies feminine gender, and wardrobe cranium CT examination is: multiple cerebral infarction; Outpatient service is intended and is hospitalized and be admitted to hospital with " multiple cerebral infarction " " hypertension (II level) ".

While in hospital gives medicine of the present invention and adds Mel 100g, is combined into ball, 2 times/day, sooner or later respectively obeys 14 days one courses of treatment 1 time.And advise functional exercise.

1 month future trouble myasthenia of limbs and dysfunction take a turn for the better.Left side upper and lower extremities muscular strength, muscular tension have slightly and weaken after continuing to take medicine 3 months, 4 grades of muscular strengths, and left hand held object obstacle is clearly better, and walking step state has not steady slightly.The patient recovers normal after 6 months.

More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; The present invention is not restricted to the described embodiments; That describes in the foregoing description and the description just explains principle of the present invention; Under the prerequisite that does not break away from spirit and scope of the invention, the present invention also has various changes and modifications, and these variations and improvement all fall in the scope of the invention that requires protection.The present invention requires protection domain to be defined by appending claims and equivalent thereof.

Claims (2)

1. Chinese medicine composition that is used to treat cerebral infarction sequela, it is characterized in that: described compositions is made up of the component of following weight portion,

Rhizoma Anemones Altaicae 15-25 part, Radix Notoginseng 8-15 part, Radix Morindae Officinalis 5-15 part, Herba Cistanches 5-15 part, Carapax et Plastrum Testudinis 15-30 part, calcined DENS DRACONIS 20-35 part, Radix Scrophulariae 15-25 part, Radix Cyathulae 10-20 part, Bombyx Batryticatus 15-25 part, Scorpio 5-10 part, Eupolyphaga Seu Steleophaga 5-15 part, Hirudo 5-15 part, Zaocys 15-25 part, Rhizoma Gastrodiae 5-15 part, Radix Puerariae 15-25 part, Pheretima 5-15 part, Semen Cassiae 10-20 part.

2. a kind of Chinese medicine composition that is used to treat cerebral infarction sequela according to claim 1 is characterized in that: optimum weight part of said each component does,

20 parts of Rhizoma Anemones Altaicaes, 12 parts of Radix Notoginseng, 10 parts of Radix Morindae Officinaliss, 10 parts of Herba Cistanches, 20 parts of Carapax et Plastrum Testudiniss, 30 parts of calcined DENS DRACONISs, 20 parts of Radix Scrophulariaes, 15 parts of Radix Cyathulaes, 20 parts of Bombyx Batryticatus, 8 parts of Scorpio, 10 parts of Eupolyphaga Seu Steleophagas, 10 parts of Hirudos, 20 parts of Zaocyss, 10 parts in Rhizoma Gastrodiae, 20 parts of Radix Puerariaes, 10 parts of Pheretimas, 15 parts of Semen Cassiae.