CN1985965A - Medicine for treating coronary heart disease and cerebral thrombus and its preparing method - Google Patents
Medicine for treating coronary heart disease and cerebral thrombus and its preparing method Download PDFInfo
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Abstract
The medicine for treating coronary heart disease and cerebral thrombus is prepared with motherwort, gingko leaf, astragalus root ginseng, red sage and other over 20 kinds of Chinese medicinal materials in certain weight proportion. It is prepared into medicine powder, capsule, bolus or tablet. It has functions of reducing blood fat, lowering blood viscosity, reducing cholesterol and promoting blood circulation to disperse blood clots, and possesses high curative rate.
Description
1. technical field
The present invention relates to a kind of medicine for the treatment of coronary heart disease, cerebral thrombosis simultaneously, is to be the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.
2. background technology
Last century end, the United Nations's health organization once proposed before 2004, captured " four big killers " the disease treatment difficult problem that comprises coronary heart disease, cerebral thrombosis.Also not having a kind of Chinese patent medicine to be sure about up to now both at home and abroad and cure coronary heart disease, cerebral thrombosis. the number that cardiovascular and cerebrovascular disease is died from the whole nation every year accounts for about 1/3rd of total toll, and 300 people on average per hour die.And along with the evolution of being becoming tight of social population's aging, living standard well-to-do levelization, life rhythm day, the extent of injury of cardiovascular and cerebrovascular disease also can be more and more higher, and harm crowd's age also can be more and more littler.
The domestic and international at present treatment subject matter to primary disease is:
[1] big with the western medicine side effect, the relapse rate height, especially cerebral thrombus patient's rehabilitation rate only is 10-30%.
[2] use Chinese traditional treatment owing to be subjected to the restriction of traditional theory, the one, always on prescription be unable to do without suppressing the hyperactive liver to relieve the wind syndrome, rush down turbidly reduce phlegm, theory and methods such as warming and recuperating the kidney-YANG, consciousness and resuscitation restoring, do not give prominence to blood circulation promoting and blood stasis dispelling with, do not catch the treatment emphasis; The 2nd, what forefathers were unused in medication dare not use, and moderns useful do not think usefulness through studies have shown that with it yet, have lost the chance of defeating by a surprise move.Therefore with Chinese medicine coronary heart disease, cerebral thrombosis, only be in the level that effective percentage is higher, cure rate is lower.
3. summary of the invention
Purpose of the present invention provides and a kind ofly can treat coronary heart disease, cerebral thrombosis simultaneously, and broad covered area, with strong points, coronary heart disease, cerebral thrombosis treatment agent that cure rate rehabilitation rate is high.
Another object of the present invention provides the preparation method of this coronary heart disease, cerebral thrombosis treatment agent.
Solution of the present invention:
[1] communicate according to cardiovascular and cerebrovascular vessel, the principle that pathogeny is closely related is taked treating different diseases with the same therapeutic principle, is taken into account the principle prescription of special procuring.
[2] not disturbed by presentation, give prominence to and strengthen blood circulation promoting and blood stasis dispelling, improve the efficacy of a drug of heart and brain blood flow and reduction hyperlipidemia, hypercholesterolemia, but can not damage healthy energy in the blood.
[3] screen medical material meticulously, especially seek with forefathers with the relevant medical material of extensive use not again after moderns studies have shown that, in the hope of special effect.
Medicine of the present invention is made [consumption is a weight portion] by following component:
Herba Leonuri 10-30 part Folium Ginkgo 15-45 part Radix Salviae Miltiorrhizae 9-20 part
Radix Paeoniae Rubra 5-15 part Radix Notoginseng 3-9 part Radix Angelicae Sinensis 3-9 part
Semen Persicae 4-12 part Flos Carthami 4-12 part Radix Puerariae 5-15 part
Pheretima 5-15 part Olibanum 3-9 part Myrrha 3-9 part
Sanguis Draxonis 4-9 part Fructus Crataegi 6-18 part eupolyphage sece steleophaga 4-12 part
Hirudo 4-9 part Radix Ginseng 10-30 part Radix Astragali 20-50 part
Rhizoma Chuanxiong 3-9 part Ramulus Cinnamomi 5-15 part Rhizoma Gastrodiae 5-15 part
Bombyx Batryticatus 3-8 part Zaocys 3-9 part Scorpio 1-5 part
Scolopendra 0.5-1.5 part
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Herba Leonuri 15-25 part Folium Ginkgo 15-25 part Radix Salviae Miltiorrhizae 10-15 part
Radix Paeoniae Rubra 5-10 part Radix Notoginseng 4-6 part Radix Angelicae Sinensis 3-6 part
Semen Persicae 4-9 part Flos Carthami 5-9 part Radix Puerariae 5-10 part
Pheretima 5-9 part Olibanum 4-6 part Myrrha 4-6 part
Sanguis Draxonis 5-7 part Fructus Crataegi 7-12 part eupolyphage sece steleophaga 6-10 part
Hirudo 5-7 part Radix Ginseng 10-25 part Radix Astragali 20-30 part
Rhizoma Chuanxiong 4-6 part Ramulus Cinnamomi 6-12 part Rhizoma Gastrodiae 5-7 part
Bombyx Batryticatus 3-5 part Zaocys 3-6 part Scorpio 1.5-3 part
Scolopendra 0.6-1.2 part
The optimum weight proportioning of medicine of the present invention is:
12 parts of 20 parts of Radix Salviae Miltiorrhizaes of 20 parts of Folium Ginkgos of Herba Leonuri
3.5 parts of 5 parts of Radix Angelicae Sinensis of 5 portions of Radix Notoginseng of Radix Paeoniae Rubra
7 parts of 5 parts of Radix Puerariaes of 5 parts of Flos Carthamis of Semen Persicae
5 parts of 5 parts of Myrrhas of 5 parts of Olibanums of Pheretima
7 parts of 7 parts of eupolyphage sece steleophagas of 5 portions of Fructus Crataegis of Sanguis Draxonis
30 parts of 10 parts of Radixs Astragali of 5 parts of Radix Ginsengs of Hirudo
5 parts in 7 parts of Rhizoma Gastrodiaes of 5 parts of Ramulus Cinnamomi of Rhizoma Chuanxiong
2 parts of 5 portions of Scorpios of 3.5 parts of Zaocys of Bombyx Batryticatus
1.2 parts of Scolopendras
The method of said components being made medicine of the present invention is:
[1] earlier Herba Leonuri being pulverized separately is coarse powder, and the clear water that adds 15-30% is then mixed thoroughly, puts in the container to steam 15-30 minute with temperature more than 100 degrees centigrade, takes out dry.
[2] dried Herba Leonuri coarse powder and other crude drug are crushed to 120 orders jointly, mix thoroughly.
[3] routinely with ultraviolet or the sterilization of microbeam irradiation-sterilize.
[4] with gained powder pack or capsule, also available conventional method and honey are ball or tabletting, make diffusing, capsule, ball, tablet.
Characteristics of the present invention are to hold pathogenesis, give prominence to blood circulation promoting and blood stasis dispelling, improve the cardiovascular and cerebrovascular vessel blood supply, and fundamentally reduce hyperlipidemia, high blood dense, hypercholesterolemia.There are 21 flavors to drop in the 25 flavor crude drug in the side for this reason, account for 84%; There are 174.7 weight portions to play this effect altogether in 190.2 weight portions in full side, account for 91.85%.And almost do not add any suppressing the hyperactive liver, reduce phlegm, class medicine such as the kidney invigorating, causing resuscitation with aromatic drugs.These did not have in similar prescription.
Another characteristics of the present invention are the precedents of going into diffusing, ball, capsule, tablet in treatment cardiovascular and cerebrovascular disease after initiative is concocted Herba Leonuri, the blood circulation promoting and blood stasis dispelling good medicine Folium Ginkgo and the Herba Leonuri that have adopted domestic and international modern study to generally acknowledge are monarch drug in addition altogether, receive key windfall effect.
The main effect of each component of medicine of the present invention is: selecting Herba Leonuri, Folium Ginkgo for use is monarch drug, it is main because Herba Leonuri has stronger anti-thrombosis function and expansion artery blood vessel function, the characteristics of especially unique " invigorate blood circulation and not blood trouble ", real be the great dynamics blood circulation promoting and blood stasis dispelling seldom first choice of medical material; Folium Ginkgo includes flavone compound 44-78%, condenses and renders a service other pharmacopoeia that wins far away for falling hyperlipidemia, hypercholesterolemia, antiplatelet.Under monarch drug, be aided with 14 flavor blood-activating stasis-removing kind medical materials such as Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Notoginseng, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Radix Puerariae, Pheretima, Olibanum, Myrrha, Sanguis Draxonis, eupolyphage sece steleophaga, Hirudo, Fructus Crataegi again, drug effect is heightened.Wherein Radix Salviae Miltiorrhizae is the ideal medicament of expansion artery blood vessel, and eupolyphage sece steleophaga, Hirudo energy removing blood stasis are assaulted fortified position and advanced, and Pheretima, Hirudo have dissolves outmoded thrombosis function, and these all are that blood flow, unobstructed blood vessel play an important role.Radix Ginseng, Radix Astragali strongly invigorating primordial QI, vim and vigour in the component, Rhizoma Chuanxiong, Ramulus Cinnamomi energy warming middle-JIAO yang invigorating all help qi and blood circulation.In the component Rhizoma Gastrodiae, Bombyx Batryticatus, Zaocys, Scorpio, Scolopendra collateral dredging, endogenous wind stopping are arranged, the pain effect of dispelling, though also favourable to treatment cardiovascular patient, mainly be for cerebral thrombosis treatment required; Simultaneously, Semen Persicae in the component, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae have special effect to expansion brain blood capillary cerebral blood flow increasing amount, and the effect of the unique protection cerebral ischemia of Radix Notoginseng cell all is that heart and brain are ruled together and created condition.
The using method of medicine of the present invention: the every clothes of powder 3-5 gram, day clothes two to three times, boiled water send down.Taboo: have cerebral hemorrhage or internal organs, retinal hemorrhage person to avoid clothes; Be not taken by pregnant women.(capsule, ball, tablet dosage are pressed the powder equivalent conversion).
Drug use result of the present invention shows following advantage:
[1] the treatment broad spectrum activity is strong, the cure rate height.As long as after make a definite diagnosis coronary heart disease, the cerebral thrombus patient who causes cerebral ischemia to cause because of arteriosclerosis, taking medicine of the present invention, all about 8-25 days, obtain obvious curative effects, all can fully recover more than 90% after 3 courses of treatment (moon) of taking medicine.
[2] deformity that do not fall of treatment cerebral thrombosis paralysed patient rehabilitation rate height, great majority.Drug therapy of the present invention is crossed 5 brain bolt paralytics, and as seen wherein 4 people's rehabilitations are higher than at present the rehabilitation rate of 10-30% both at home and abroad.
[3] indivedual patients with severe symptoms take medicine of the present invention (having 4 people to reach 3-5) for the prevention purpose throughout the year, and are without any side effects.
[4] medicine of the present invention need not decoct, taking convenience.And since be loose, capsule, ball, tablet, save the treatment cost greatly than decoction, be again country's saving Chinese material medicine resource, help sustainable development.
Drug therapy patient's catalog of the present invention:
| Classification | The treatment number | Effective number | Effective percentage % | The healing number | Cure rate % | Remarks |
| Cerebral thrombosis | 10 | 10 | 100 | 9 | 90 | |
| Coronary heart disease | 90 | 90 | 100 | 88 | 97 | |
| Add up to | 100 | 100 | 100 | 97 | 97 |
4. the specific embodiment
Embodiment
Take by weighing raw material in following ratio:
Herba Leonuri 20kg Folium Ginkgo 20kg Radix Salviae Miltiorrhizae 12kg Radix Paeoniae Rubra 5kg
Radix Notoginseng 5kg Radix Angelicae Sinensis 3.5kg Semen Persicae 5kg Flos Carthami 5kg Radix Puerariae 7kg
Pheretima 5kg Olibanum 5kg Myrrha 5kg Sanguis Draxonis 5kg Fructus Crataegi 7kg
Eupolyphage sece steleophaga 7kg Hirudo 5kg Radix Ginseng 10kg Radix Astragali 30kg Rhizoma Chuanxiong 5kg
Ramulus Cinnamomi 7kg Rhizoma Gastrodiae 5kg Bombyx Batryticatus 3.5kg Zaocys 5kg Scorpio 2kg
Scolopendra 1.2kg
Earlier Herba Leonuri is pulverized and be coarse powder, the clear water that adds 15-30% is mixed thoroughly, putting in the container takes out dry with temperature steaming more than 100 degrees centigrade after 15-30 minute, be crushed to 120 orders jointly with other crude drug then, mix thoroughly, routinely with ultraviolet or the microbeam irradiation-sterilize poison that goes out, obtain pack behind the powder, capsule, can be ball with honey routinely also or be pressed into tablet.
Attached: a small amount of case of Drug therapy of the present invention
Li Xiyao, the man, 65 years old (inventor) suffered from ischemic cardiomyopathy type coronary heart disease before 6 years, be in hospital and adopted western medical treatment in 23 days, NAOXINTONG 1 wheat harvesting period is taken in the recurrence again in 8 days of leaving hospital, in advance effectively, the later stage is invalid, must take alleviations such as pills for curing heart disease in every 1-2 hour, the time dying sensation arranged.The back is under the desire of seeking survival is supported, browse a large amount of Chinese and western medicine nationalitys, filter out side at the bottom of several traditional Chinese medical science, test is carried out preferred one by one, to relate to again control this disease 40 surplus kind of Chinese crude drug break into medicated powder respectively, and after taking best end side, did pharmacopoeia, a dose plus-minus in every 5-10 days and revise, " with the body reagent " becomes this side eventually.Take behind this powder and promptly to eliminate all symptoms in 20 days, the 6-8 kilometer of climbing the mountain away every day is calm and confident, so far always.
Dragon and phoenix shake, the man, and 74 years old, suffered from cerebral thrombosis before 4 years, after leaving hospital, western medical treatment still is paralyzed in bed, and the mood impatience is fallen thing, is sworn at people, and children serve in shifts, and the thousands of units of cost such as light of taking NAOXINTONG, resurrection are still invalid.After change this medicine of clothes, afternoon can oneself walk about to the open air after more than 20 day, the energy walking of oneself going into the street is recurred so far after one month.
Li Yukun, male .50 year, because of the brain stem blood vessel blockage, general paralysis is remained unconscious before 2 years, and hospitalization adds this medicine simultaneously, just can accompany mountain-climbing down wife behind two wheat harvesting periods and take exercises.So far not recurrence.
Meng Xianbin, Liu love blue man and wife, equal 64 years old, and people from Weifang, Shandong, with trouble hypertension, cerebral thrombosis, coronary heart disease for many years, headache, dizzy, numb limbs and tense tendons pain, heart district feels oppressed, weak all over, blood pressure was not once all cured with multiple Chinese and western drugs treatment generally up to 170/120 millimetres of mercury.Change this medicine of clothes April in this year, existing to cure, blood pressure recovers normal behind the depressor of stopping using.
Zheng, the man, 56 years old, retired policeman suffered from coronary heart disease before 3 years, sensation of oppression over the chest with shortness of breath, it is weak, look angry to walk, and livid purple at the bottom of the tongue of tongue limit, yellowish fur is thick and heavy, takes 25 days symptoms of this medicine and is clearly better, recovery from illness after 4 months.
Liu, the man, 67 years old, coronary heart disease was suffered from before about ten years by retired employees of agricultural bank, had no resolution with multiple Drug therapy, used instead behind this medicine and to take effect, obviously to take a turn for the better in 8 days in 5 days, will take as the daily health caring medicine by this medicine after the recovery from illness throughout the year, over 4 years without any toxicity.
Li Yonglu, Zhang Qin, the man equal 66 years old, suffered from coronary heart disease before 6 years, sensation of oppression over the chest with shortness of breath, the former tachycardia, per minute 110-120 time, latter's premature beat.After taking this medicine simultaneously, heart rate all recovers normally, recovery from illness after month, not recurrence so far.Similar case has hundred people, and stands on-the-spot investigation.
Claims (7)
1. the medicine that can treat coronary heart disease, cerebral thrombosis simultaneously is characterized in that it is the medicament of being made by the following weight proportion raw material:
Herba Leonuri 10-30 part Folium Ginkgo 15-45 part Radix Salviae Miltiorrhizae 9-20 part
Radix Paeoniae Rubra 5-15 part Radix Notoginseng 3-9 part Radix Angelicae Sinensis 3-9 part
Semen Persicae 4-12 part Flos Carthami 4-12 part Radix Puerariae 5-15 part
Pheretima 5-15 part Olibanum 3-9 part Myrrha 3-9 part
Sanguis Draxonis 4-9 part Fructus Crataegi 6-18 part eupolyphage sece steleophaga 4-12 part
Hirudo 4-9 part Radix Ginseng 10-30 part Radix Astragali 20-50 part
Rhizoma Chuanxiong 3-9 part Ramulus Cinnamomi 5-15 part Rhizoma Gastrodiae 5-15 part
Bombyx Batryticatus 3-8 part Zaocys 3-9 part Scorpio 1-5 part
Scolopendra 0.5-1.5 part
2. medicine for the treatment of coronary heart disease, cerebral thrombosis simultaneously according to claim 1, wherein the weight proportion of each raw material is:
Herba Leonuri 15-25 part Folium Ginkgo 15-25 part Radix Salviae Miltiorrhizae 10-15 part
Radix Paeoniae Rubra 5-10 part Radix Notoginseng 4-6 part Radix Angelicae Sinensis 3-6 part
Semen Persicae 4-9 part Flos Carthami 5-9 part Radix Puerariae 5-10 part
Pheretima 5-9 part Olibanum 4-6 part Myrrha 4-6 part
Sanguis Draxonis 5-7 part Fructus Crataegi 7-12 part eupolyphage sece steleophaga 6-10 part
Hirudo 5-7 part Radix Ginseng 10-25 part Radix Astragali 20-30 part
Rhizoma Chuanxiong 4-6 part Ramulus Cinnamomi 6-12 part Rhizoma Gastrodiae 5-7 part
Bombyx Batryticatus 3-5 part Zaocys 3-6 part Scorpio 1.5-3 part
Scolopendra 0.6-1.2 part
3. the medicine that can treat coronary heart disease, cerebral thrombosis simultaneously according to claim 1, wherein each proportion of raw materials is:
12 parts of 20 parts of Radix Salviae Miltiorrhizaes of 20 parts of Folium Ginkgos of Herba Leonuri
3.5 parts of 5 parts of Radix Angelicae Sinensis of 5 portions of Radix Notoginseng of Radix Paeoniae Rubra
7 parts of 5 parts of Radix Puerariaes of 5 parts of Flos Carthamis of Semen Persicae
5 parts of 5 parts of Myrrhas of 5 parts of Olibanums of Pheretima
7 parts of 7 parts of eupolyphage sece steleophagas of 5 portions of Fructus Crataegis of Sanguis Draxonis
30 parts of 10 parts of Radixs Astragali of 5 parts of Radix Ginsengs of Hirudo
5 parts in 7 parts of Rhizoma Gastrodiaes of 5 parts of Ramulus Cinnamomi of Rhizoma Chuanxiong
2 parts of 5 portions of Scorpios of 3.5 parts of Zaocys of Bombyx Batryticatus
1.2 parts of Scolopendras
4. according to claim 1,2 or 3 described medicines for the treatment of coronary heart disease, cerebral thrombosis simultaneously, it is characterized in that said medicament is the above dosage form of saying of any pharmaceutics.
5. it is characterized in that according to power 4 described medicines for the treatment of coronary disease and cerebral thrombosis simultaneously said medicament is powder, capsule, honeyed pill or tablet.
6. the described preparation method for the treatment of coronary heart disease, cerebral thrombosis medicine simultaneously of claim 5, it is characterized in that earlier Herba Leonuri being pulverized being coarse powder, adding the 15-30% clear water mixes thoroughly, putting in the container takes out dry with temperature steaming more than 100 degrees centigrade after 15-30 minute, be crushed to 120 orders jointly with other crude drug then, mix thoroughly, routinely with ultraviolet or the microbeam irradiation-sterilize poison that goes out, obtain pack or capsule behind the powder, can be ball with honey routinely also or be pressed into tablet.
Described in the claim 6 with Herba Leonuri in the concocting method of steaming 15-30 minute more than 100 degrees centigrade, comprise other processing, the process of preparing Chinese medicine, the extracting method that carry out with this temperature.
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| CN2006101079181A CN1985965B (en) | 2006-07-23 | 2006-07-23 | Medicine for treating coronary heart disease and cerebral thrombus and its preparing method |
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| CN1985965B CN1985965B (en) | 2010-09-01 |
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| CN105456743A (en) * | 2015-12-02 | 2016-04-06 | 济南舜祥医药科技有限公司 | Chinese medicine for treating cerebrovascular disease and preparation method thereof |
| CN106177751A (en) * | 2016-07-08 | 2016-12-07 | 刘福坤 | A kind of method utilizing five kinds of skill of handling needles to coordinate treatment by Chinese herbs cerebral thrombosis |
| CN107441295A (en) * | 2017-08-15 | 2017-12-08 | 山东仲景健康服务有限公司 | One kind is for blood stasis constitution massage Chinese medicine oil breast |
| CN111000893A (en) * | 2019-11-29 | 2020-04-14 | 沈阳药科大学 | Medical application of leech and ligusticum wallichii capsule |
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