CN102764226B - Eyebrow nourishing liquid, and preparation method and application thereof - Google Patents
Eyebrow nourishing liquid, and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses eyebrow nourishing liquid, and a preparation method and application thereof. The eyebrow nourishing liquid is prepared from the following main active ingredients: turnip, ginger, woad, ginseng and honey. The eyebrow nourishing liquid, and the preparation method and the application thereof have the advantages that according to market demand, Xinjiang characteristic resources are developed to the maximum extent; five Chinese medicines, namely the turnip, the ginger, the woad, the ginseng and the honey which serve as natural plant raw materials, are combined in an optimal ratio, and an appropriate number of preservatives are added into the five Chinese medicines and stirred uniformly to prepare the eyebrow nourishing liquid; by the eyebrow nourishing liquid, requirements of people whose eyebrows are a few, and come off are met, and the pursuit of people for beauty and a high spirit quality life is met; and the eyebrow nourishing liquid is light yellow liquid and high in compliance, has unique honey fragrance, and does not cover skin and eyebrow colors.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to breeding eyebrow liquid and its preparation method and application.
Background technology
Radix Brassicae rapae (
brassica rapal .), Cruciferae, Xinjiang Uygur is referred to as Qiamuwuer, Solanum muricatum, and Radix Brassicae rapae is nutritious, contains a large amount of sugar, starch and vitamin.
Isatis indigotica Fort. (
isatis tinctorial .), be referred to as the Wu Sima grass in Xinjiang, give birth to the eyebrow grass, be the Uygur nationality a kind of living eyebrow plant of commonly using among the people.Almost every household is all at Around the house plantation Isatis indigotica Fort. (Wu Sima) for the uygur nationality of Xijiang, and people squeeze juice with its leaf and smear two eyebrows of girl every day, make eyebrows shiny black close, until grow up, as washing one's face, day by day, year after year, pass on from generation to generation everyday.The technology that this traditional promotion eyebrow is grown and peerless to treasuring in China various nationalities of eyebrow.
Rhizoma Zingiberis Recens (
zingiber officinalerosc.) warm in nature, have and induce sweat, the effect of dispersing, so the hair growth promoting of external Rhizoma Zingiberis Recens can increase local blood circulation really, hair follicle stimulating is opened, and impels hair regeneration.
Radix Ginseng (
panax ginsengc. A. Mey.) flat, the sweet in the mouth of property, micro-hardship, tepor.Multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves.
Mel (Mel) is Apidae insecticide apis cerana
apis ceramafabricius or apis mellifera Linnaeus
apis melliferathe honey that Linnacus makes is a kind of nutritious natural nourishing food.According to one's analysis, the trace element that contains plurality of inorganic salt, organic acid and the useful health close with human serum concentration, and the plurality of enzymes such as amylase, oxidase, reductase, can help the cellulose metabolism, there is the effect of nourishing, removing toxic substances, beauty face-whitening-nourishing.
Chinese invention patent ZL921148089 " Isatis indigotica Fort. eye cosmetic and preparation method thereof " and ZL200910113424 " indirubin is educated the purposes of hair as preparation ", technique and the purposes of indirubin in promoting hair growth of extracting indirubin from Isatis indigotica Fort. are disclosed, but its composition is single, and extracting method is more complicated.
Along with the raising of people's living standard, people to the pursuit of cosmetics also gradually by safety to the effect transition, particularly, to the demand of the effect cosmetics of pure natural, especially receive in the world very big concern.
Summary of the invention
Purpose of the present invention is exactly for above-mentioned defect of the prior art, provides a kind of multicomponent to mix, and educates eyebrow effective, and preparation technology simply supports eyebrow liquid.
To achieve these goals, technical scheme provided by the invention is: a breeding eyebrow liquid, the Main Function composition of described foster eyebrow liquid is Radix Brassicae rapae, Rhizoma Zingiberis Recens, Isatis indigotica Fort., Radix Ginseng and Mel.
Further, in above-mentioned foster eyebrow liquid, each main component is Radix Brassicae rapae solution, Rhizoma Zingiberis Recens solution, Isatis indigotica Fort.-Radix Ginseng ethanol extract and Mel.
Further, the weight ratio of the Main Function composition of above-mentioned foster eyebrow liquid is Radix Brassicae rapae: Rhizoma Zingiberis Recens: Isatis indigotica Fort.: Radix Ginseng is 80-120:80-120:1-5:1-5; The 1-10% of the foster eyebrow liquid of described Mel.
Further, in above-mentioned foster eyebrow liquid, also be added with antiseptic, 1% of the gross weight that the addition of antiseptic is foster eyebrow liquid.
Further, the weight ratio of the Main Function composition of above-mentioned foster eyebrow liquid is Radix Brassicae rapae: Rhizoma Zingiberis Recens: Isatis indigotica Fort.: Radix Ginseng is 40:40:1:1; 5% of the gross weight that the addition of described Mel is foster eyebrow liquid.
Another object of the present invention has been to provide the preparation method of above-mentioned foster eyebrow liquid, comprises the following steps:
1) take by weight ratio each raw material;
2) by after Radix Brassicae rapae section, according to the weight ratio Radix Brassicae rapae: water is that 1:10 adds water, decocts and extracts 0.5-1.5 hour, filters, by the concentrated Radix Brassicae rapae solution that obtains of filtrate;
3) by Rhizoma Zingiberis Recens according to the weight ratio Rhizoma Zingiberis Recens: water is that 1:1 adds water, and the rear filter and remove residue of squeezing the juice, obtain Rhizoma Zingiberis Recens solution;
4) Isatis indigotica Fort. and Radix Ginseng are pulverized respectively, sieved, and mix according to weight ratio 1:1, then add 70% alcohol reflux 0.5-1.5 hour of 20 times of mixture total weight amounts, filter and obtain Isatis indigotica Fort.-Radix Ginseng ethanol extract; (because Chinese crude drug normally will separately shattering of differing texture)
5) by step 2), the Radix Brassicae rapae solution, Rhizoma Zingiberis Recens solution and the Isatis indigotica Fort. that obtain of step 3) and step 4)-Radix Ginseng ethanol extract mixed according to volume ratio 1:1:0.5, add again the Mel of foster eyebrow liquid gross weight 1-10% and the antiseptic of foster eyebrow liquid gross weight 1%, room temperature is placed 24-48 hour, obtains supporting eyebrow liquid.
The preparation method of above-mentioned foster eyebrow liquid, described step 2) in, decocting time is 1 hour; Filtering the order number is 500 orders.
The preparation method of above-mentioned foster eyebrow liquid, in described step 4), crossing grit number is 100 orders; 70% alcohol reflux time was 1 hour; Filtering the order number is 500 orders.
The preparation method of above-mentioned foster eyebrow liquid, in described step 5), 5% of the gross weight that the addition of Mel is foster eyebrow liquid; Room temperature standing time is 36 hours.
The 3rd purpose of the present invention has been to provide the application of foster eyebrow liquid in the few eyebrow of scarce eyebrow falls the eyebrow treatment.
Beneficial effect of the present invention is: the present invention is in conjunction with the market demand, excavate to greatest extent the Xinjiang characteristic resource, by the natural plant raw material Radix Brassicae rapae, Rhizoma Zingiberis Recens, Isatis indigotica Fort., Radix Ginseng, the Mel Chinese medicine of the five flavours is combined, obtain best proportioning, appropriate antiseptic in addition again, stir, obtain supporting eyebrow liquid, met the eyebrow rareness, fall the demand of eyebrow and the vast colony of scarce eyebrow, people have also been met to pursuit beautiful and high spiritual quality life, supporting eyebrow liquid is weak yellow liquid, there is unique sweet fragrance, and do not hide skin and eyebrow color, there is good compliance, the purpose that adds Mel is to contain plurality of enzymes in Mel can decompose by the accelerating fibers element, make solution clarify and have additional nutrients.
The specific embodiment
embodiment 1:
Support formula and the preparation method of eyebrow liquid:
Formula: Radix Brassicae rapae 800g, Rhizoma Zingiberis Recens 800g, Isatis indigotica Fort. 10g, Radix Ginseng 10g, Mel 1%.
Preparation method follows these steps to carry out:
A, Radix Brassicae rapae 800g section, Radix Brassicae rapae in mass ratio: water is that 1:10 adds water, decocts and extracts 0.5 hour, crosses 500 order filter clothes, gets filtrate, and concentrated Radix Brassicae rapae solution to 800 milliliter;
B, with the ratio of mass ratio 1:1, add purified water to squeeze the juice Rhizoma Zingiberis Recens 800g, remove slag, extracting juice, obtain 800 milliliters of Rhizoma Zingiberis Recens solution;
C, Isatis indigotica Fort. 10g, Radix Ginseng 10g are pulverized, cross 100 mesh sieves, mix homogeneously, with 70% alcohol reflux of 20 times of Isatis indigotica Fort. and Radix Ginseng mixture gross masses 0.5 hour, cross 500 order filter clothes, obtains filtrate and be concentrated into 400 milliliters;
D, three kinds of solution that step a, b, c are obtained mix, and add successively 1% Mel, antiseptic 1%, stir, and room temperature is placed 24 hours, can obtain supporting eyebrow liquid.
embodiment 2:
Support formula and the preparation method of eyebrow liquid:
Formula: Radix Brassicae rapae 1200g, Rhizoma Zingiberis Recens 1200g, Isatis indigotica Fort. 50g, Radix Ginseng 50g, Mel 10%.
Preparation method follows these steps to carry out:
A, Radix Brassicae rapae 1200g section, Radix Brassicae rapae in mass ratio: water is that 1:10 adds water, decocts and extracts 1.5 hours, crosses 500 order filter clothes, gets filtrate, and concentrated Radix Brassicae rapae solution to 1200 milliliter;
B, with the ratio of mass ratio 1:1, add purified water to squeeze the juice Rhizoma Zingiberis Recens 1200g, remove slag, extracting juice, obtain 1200 milliliters of Rhizoma Zingiberis Recens solution;
C, Isatis indigotica Fort. 50g, Radix Ginseng 50g are pulverized, cross 100 mesh sieves, mix homogeneously, with 70% alcohol reflux of 20 times of Isatis indigotica Fort. and Radix Ginseng mixture gross masses 1.5 hours, cross 500 order filter clothes, obtains filtrate and be concentrated into 600 milliliters;
D, three kinds of solution that step a, b, c are obtained mix, and add successively 10% Mel, antiseptic 1%, stir, and room temperature is placed 48 hours, can obtain supporting eyebrow liquid.
embodiment 3:
Support formula and the preparation method of eyebrow liquid:
Formula: Radix Brassicae rapae 1000g, Rhizoma Zingiberis Recens 1000g, Isatis indigotica Fort. 25g, Radix Ginseng 25g, Mel 5%.
Preparation method follows these steps to carry out:
A, Radix Brassicae rapae 1000g section, Radix Brassicae rapae in mass ratio: water is that 1:10 adds water, decocts and extracts 1 hour, crosses 500 order filter clothes, gets filtrate, and concentrated Radix Brassicae rapae solution to 1000 milliliter;
B, with the ratio of mass ratio 1:1, add purified water to squeeze the juice Rhizoma Zingiberis Recens 1000g, remove slag, extracting juice, obtain 1000 milliliters of Rhizoma Zingiberis Recens solution;
C, Isatis indigotica Fort. 25g, Radix Ginseng 25g are pulverized, cross 100 mesh sieves, mix homogeneously, with 70% alcohol reflux of 20 times of Isatis indigotica Fort. and Radix Ginseng mixture gross masses 1 hour, cross 500 order filter clothes, obtains filtrate and be concentrated into 500 milliliters;
D, three kinds of solution that step a, b, c are obtained mix, and add successively 5% Mel, antiseptic 1%, stir, and room temperature is placed 36 hours, can obtain supporting eyebrow liquid.
embodiment 4:
Carry out foster eyebrow with above-mentioned foster eyebrow liquid and educated the animal experiment that eyebrow is given birth to the eyebrow effect.
1, experiment material:
Laboratory animal:
The Kunming white mice, male and female half and half, body weight 18 ± 2g, bought by autonomous region of Uygur disease control prevention and control center Experimental Animal Center, the animal credit number: SCXK(is new) 2011-0001.
Tested material:
A: administration group (supporting eyebrow liquid): the foster eyebrow liquid obtained by the inventive method.
B: matched group (distilled water): distilled water.
C: positive controls (ZHANGGUANG 101): buy commercially available hair growth promoting commodity (ZHANGGUANG101 YUFAJI, lot number 20100701, BeiJing ZhangGuang's 101 development in science and technology company limiteies).
Reagent source:
Sodium sulfide: Tianjin chemical reagent six three subsidiary factories of factory, lot number 20101106;
Formaldehyde: Xi'an chemical reagent factory, lot number 100530.
Test method:
Administration is lost hair or feathers the white mice back in first 24 hours with 8% sodium sulfide solution, the unhairing area is about 4 square centimeters, after 2 minutes, with wet cloth, wipes the hair come off, and guarantees that local hair is taken off fully and not damaged.
Animal grouping and administration:
Get 48 of depilation white mice, be divided at random four groups of negative control group (distilled water), positive controls (ZHANGGUANG 101) and the large small dose group of administration (supporting eyebrow liquid), every group 12, each group is all directly smeared matched group (distilled water), positive controls (ZHANGGUANG 101) and the large small dose group of administration (supporting eyebrow liquid) at the depilation position, smear at regular time and quantity twice every day, smear about 0.20mL, observe every day, continuous 23 days at every turn.
Observation index:
The time that every day, every white mice depilation district hair increased (my god);
Histopathologic examination;
After educating hair experiment end, to break, the vertebra method is put to death white mice;
The position of smearing at each group white mice back cuts skin sample;
Pathology slice probing method, fix by 10% formalin routinely, dehydration, specimens paraffin embedding slices, hematoxylin-eosin staining;
The histology who observes the white mice skin follicle under light microscopic changes, and counting high dermis hair follicle number.
Statistical procedures:
Experimental data is with mean ± standard deviation
mean t check between the employing group.
Statistical result shows:
The large small dose group of administration (supporting eyebrow liquid) compares with negative control group (distilled water), but the large small dose group highly significant of administration shortens the time (P<0.01) of hair growth;
The large small dose group of administration (supporting eyebrow liquid) compares with positive controls (ZHANGGUANG 101), the large small dose group of administration (supporting eyebrow liquid) can significantly shorten the time (P<0.05) of hair growth, and experimental result is supported the impact of eyebrow liquid on depilation district, white mice back skin growth in Table 1
.
Table 1
Annotate: administration group (supporting eyebrow liquid) after 23 days with the large small dose group of administration (supporting eyebrow liquid) 0 day relatively, * is P<0.05.
Histopathologic examination:
The histopathological examination result shows: the large small dose group of administration (supporting eyebrow liquid), matched group (distilled water) and positive controls (ZHANGGUANG 101) white mice skin of back structure are all complete, and it is downright bad that epidermis has no;
Corium has no cell infiltration;
Each group all is shown in the normal hair follicle of structure;
With 100 times of visual field calculating numbers, the large small dose group of administration (supporting eyebrow liquid) and positive controls (ZHANGGUANG 101) hair follicle digital display work are more than matched group (distilled water).
Statistical result shows:
The large small dose group of administration (supporting eyebrow liquid) compares with matched group (distilled water), and the large small dose group of administration (supporting eyebrow liquid) high dermis hair follicle number obviously increases, and (P<0.05) the results are shown in Table 2 foster eyebrow liquid test block, white mice back skin follicle is counted
.
Table 2
Annotate: the heavy dose of group of administration (supporting eyebrow liquid) compares with negative control group (distilled water), and administration group (supporting eyebrow liquid) hair follicle digital display work is more than matched group (distilled water) *
p<0.05; The large small dose group of administration (supporting eyebrow liquid) does not have significant difference with positive controls (ZHANGGUANG 101) hair follicle number.
White mice educates a mao rear dermatopathology and observes:
Experiment conclusion:
The large small dose group of administration (supporting eyebrow liquid) is on white mice hair growth impact experiment, and result shows:
The large small dose group of administration (foster eyebrow liquid) compares with matched group (distilled water), the time of administration group (supporting eyebrow liquid) rear hair growth but the shortening white mice of highly significant loses hair or feathers, confirms that administration group (foster eyebrow liquid) has remarkable trichogenous effect;
The histopathological examination result shows, the large small dose group of administration (supporting eyebrow liquid) and matched group (distilled water) comparison, white mice skin of back structural integrity; It is downright bad that epidermis has no; Corium has no cell infiltration; The large small dose group of administration and matched group all are shown in the normal hair follicle of structure;
The large small dose group of administration (supporting eyebrow liquid) hair follicle is obviously more than matched group (distilled water).
The large small dose group of proof administration (supporting eyebrow liquid) is safe and effective to dermatologic.
White mice educates after hair experiment finishes, and disconnected vertebra is put to death, and gets butt, and butt tissue shows through the pathological examination result, and the large small dose group of administration (supporting eyebrow liquid) compares with negative control group (distilled water) and positive controls (ZHANGGUANG 101):
White mice skin of back structural integrity, it is downright bad that epidermis has no;
Corium has no cell infiltration;
Equal normal hair follicles of high-visible structure;
The large small dose group of administration (supporting eyebrow liquid) hair follicle is obviously more than matched group (distilled water).
The large small dose group of proof administration (supporting eyebrow liquid) is to dermatologic safety, and hair follicle is obviously more than other groups.
Finally it should be noted that: the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment, the present invention is had been described in detail, for a person skilled in the art, its technical scheme that still can put down in writing aforementioned each embodiment is modified, or part technical characterictic wherein is equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (7)
1. a breeding eyebrow liquid, is characterized in that, the Main Function composition of described foster eyebrow liquid is Radix Brassicae rapae, Rhizoma Zingiberis Recens, Isatis indigotica Fort., Radix Ginseng and Mel; The weight ratio of the Main Function composition of described foster eyebrow liquid is Radix Brassicae rapae: Rhizoma Zingiberis Recens: Isatis indigotica Fort.: Radix Ginseng is 80-120:80-120:1-5:1-5; The addition of described Mel is the 1-10% of the gross weight of foster eyebrow liquid.
2. foster eyebrow liquid according to claim 1, is characterized in that, in described foster eyebrow liquid, also is added with antiseptic, 1% of the gross weight that the addition of antiseptic is foster eyebrow liquid.
3. foster eyebrow liquid according to claim 2, is characterized in that, the weight ratio of the Main Function composition of described foster eyebrow liquid is Radix Brassicae rapae: Rhizoma Zingiberis Recens: Isatis indigotica Fort.: Radix Ginseng is 40:40:1:1; 5% of the gross weight that the addition of described Mel is foster eyebrow liquid.
One kind as arbitrary as claim 1-3 as described in the preparation method of foster eyebrow liquid, it is characterized in that, comprise the following steps:
1) take by weight ratio each raw material;
2) by after Radix Brassicae rapae section, according to the weight ratio Radix Brassicae rapae: water is that 1:10 adds water, decocts and extracts 0.5-1.5 hour, filters, by the concentrated Radix Brassicae rapae solution that obtains of filtrate;
3) by Rhizoma Zingiberis Recens according to the weight ratio Rhizoma Zingiberis Recens: water is that 1:1 adds water, and the rear filter and remove residue of squeezing the juice, obtain Rhizoma Zingiberis Recens solution;
4) Isatis indigotica Fort. and Radix Ginseng are pulverized respectively, sieved, and mix according to weight ratio 1:1, then add 70% alcohol reflux 0.5-1.5 hour of 20 times of mixture total weight amounts, filter and obtain Isatis indigotica Fort.-Radix Ginseng ethanol extract;
5) by step 2), the Radix Brassicae rapae solution, Rhizoma Zingiberis Recens solution and the Isatis indigotica Fort. that obtain of step 3) and step 4)-Radix Ginseng ethanol extract mixes, add again the Mel of foster eyebrow liquid gross weight 5% and the antiseptic of foster eyebrow liquid gross weight 1%, room temperature is placed 24-48 hour, obtains supporting eyebrow liquid.
5. the preparation method of foster eyebrow liquid according to claim 4, is characterized in that, described step 2) in, decocting time is 1 hour; Filtering the order number is 500 orders.
6. the preparation method of foster eyebrow liquid according to claim 4, is characterized in that, in described step 4), crossing grit number is 100 orders; 70% alcohol reflux time was 1 hour; Filtering the order number is 500 orders.
7. the preparation method of foster eyebrow liquid according to claim 4, is characterized in that, in described step 5), adding after Mel and antiseptic room temperature standing time is 36 hours.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103767968B (en) * | 2014-01-10 | 2016-07-13 | 新疆奥斯曼生物资源有限公司 | One educates eyebrow liquid and preparation method thereof |
| CN106267048A (en) * | 2015-05-20 | 2017-01-04 | 陆文宇 | One treats medicine for curing poliosis Chinese medicine formula and preparation method thereof |
| CN106474289A (en) * | 2016-11-28 | 2017-03-08 | 林少彬 | A kind of traditional Chinese medicine liquid for promoting eyebrow growth and preparation method thereof |
| CN111671675A (en) * | 2020-05-26 | 2020-09-18 | 新疆亲努尔生物科技有限公司 | Skin care oil containing Qamgur seed oil and preparation method and application thereof |
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| CN1088775A (en) * | 1992-12-31 | 1994-07-06 | 新疆自治区药物研究所 | Aosiman eye cosmetic and preparation method thereof |
| CN101658518A (en) * | 2009-08-19 | 2010-03-03 | 刘庆华 | Application of indirubin for preparing hair culture |
| CN102133166A (en) * | 2011-03-18 | 2011-07-27 | 乌鲁木齐一枝好生物科技有限公司 | Plant hair reviving, blacking and strengthening nutrient solution and preparation method thereof |
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| CN1088775A (en) * | 1992-12-31 | 1994-07-06 | 新疆自治区药物研究所 | Aosiman eye cosmetic and preparation method thereof |
| CN101658518A (en) * | 2009-08-19 | 2010-03-03 | 刘庆华 | Application of indirubin for preparing hair culture |
| CN102133166A (en) * | 2011-03-18 | 2011-07-27 | 乌鲁木齐一枝好生物科技有限公司 | Plant hair reviving, blacking and strengthening nutrient solution and preparation method thereof |
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