CN102762985B - 使用热休克蛋白72作为敏感生物标志物来检测急性肾损伤的诊断方法 - Google Patents

使用热休克蛋白72作为敏感生物标志物来检测急性肾损伤的诊断方法 Download PDF

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Publication number
CN102762985B
CN102762985B CN201080062143.5A CN201080062143A CN102762985B CN 102762985 B CN102762985 B CN 102762985B CN 201080062143 A CN201080062143 A CN 201080062143A CN 102762985 B CN102762985 B CN 102762985B
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China
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hsp72
biomarker
aki
renal
injury
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Chinese (zh)
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CN102762985A (zh
Inventor
诺玛·阿拉塞利·博瓦迪利亚桑多瓦尔
乔纳森·巴雷拉凯莫尔
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Universidad Nacional Autonoma de Mexico
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Universidad Nacional Autonoma de Mexico
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080062143.5A 2009-11-23 2010-11-23 使用热休克蛋白72作为敏感生物标志物来检测急性肾损伤的诊断方法 Expired - Fee Related CN102762985B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
MX/A/2009/012633 2009-11-23
MXMX/A/2009/012633 2009-11-23
MX2009012633A MX2009012633A (es) 2009-11-23 2009-11-23 Metodo de diagnostico para detectar la lesion renal aguda a traves del uso de la proteina de choque termico de 72 kda como un biomarcador sensible.
PCT/MX2010/000138 WO2011062469A2 (es) 2009-11-23 2010-11-23 Método de diagnóstico para detectar la lesión renal aguda a través del uso de la proteína de choque térmico de 72 kda como un biomarcador sensible

Publications (2)

Publication Number Publication Date
CN102762985A CN102762985A (zh) 2012-10-31
CN102762985B true CN102762985B (zh) 2015-06-17

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CN201080062143.5A Expired - Fee Related CN102762985B (zh) 2009-11-23 2010-11-23 使用热休克蛋白72作为敏感生物标志物来检测急性肾损伤的诊断方法

Country Status (8)

Country Link
US (1) US20130065239A1 (enExample)
EP (1) EP2506016B1 (enExample)
JP (1) JP5755657B2 (enExample)
CN (1) CN102762985B (enExample)
CA (1) CA2781754C (enExample)
ES (1) ES2549610T3 (enExample)
MX (1) MX2009012633A (enExample)
WO (1) WO2011062469A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013529907A (ja) 2010-05-24 2013-07-25 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク Ｎｇａｌタンパク質変異体及びその使用
EP2585827A4 (en) 2010-06-23 2013-12-04 Astute Medical Inc METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency
BR112014004389A2 (pt) 2011-08-26 2017-03-28 Astute Medical Inc métodos e composições para diagnóstico de lesão renal e insuficiência renal
CN102879584A (zh) * 2012-09-26 2013-01-16 中国人民解放军军事医学科学院基础医学研究所 一种人血液hsp70抗体胶体金标检测试纸条及其制备方法
EP2925337B1 (en) 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
KR101468047B1 (ko) * 2013-01-16 2014-12-02 고려대학교 산학협력단 열충격단백질군의 mRNA 발현 양상 분석을 통한 사인 추정방법
US11346846B2 (en) 2017-02-06 2022-05-31 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN107045594B (zh) * 2017-04-25 2018-06-26 吉林大学 一种脊柱损伤测量中x射线标志物的数字化系统
WO2020125806A1 (en) 2018-12-17 2020-06-25 Shanghai United Imaging Intelligence Co., Ltd. Systems and methods for image segmentation
CN109754394B (zh) * 2018-12-28 2021-02-23 上海联影智能医疗科技有限公司 三维医学图像处理装置及方法
CN111007255A (zh) * 2019-12-10 2020-04-14 江苏三联生物工程有限公司 一种用于肾损伤标志物检测的蛋白芯片及其制备方法
CN116449024A (zh) * 2023-04-13 2023-07-18 武汉市第三医院 Saa1作为生物标志物在预测或诊断急性肾损伤中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4035591B2 (ja) * 2003-01-24 2008-01-23 株式会社三重ティーエルオー 血管障害病態改善剤
WO2007013919A2 (en) * 2005-07-21 2007-02-01 The Johns Hopkins University Methods of detecting and treating acute kidney injury

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Heat Shock Protein Expression Is Highly Sensitive to Ischemia-Reperfusion Injury in Rat Kidneys;Ping L. Zhang et al;《ANNALS OF CLINICAL & LABORATORY SCIENCE》;20081231;第38卷(第1期);第57－63页 *
Induction and intracellular localization of HSP-72 after renal ischemia;SCOTT K.VAN WHY et al;《AM.J.PHYSIOL.RENAL PHYSIOL》;19921101;第263卷;第F769页 *
Urinary heat shock protein-72 excretion in clinical and experimental renal ischemia;Thomas Mueller et al;《PEDIATRIC NEPHROLOGY》;20021219;第18卷(第2期);第97－99页 *

Also Published As

Publication number Publication date
CN102762985A (zh) 2012-10-31
EP2506016A4 (en) 2013-01-23
CA2781754A1 (en) 2011-05-26
WO2011062469A8 (es) 2012-01-12
WO2011062469A3 (es) 2011-11-24
CA2781754C (en) 2019-09-03
WO2011062469A2 (es) 2011-05-26
JP5755657B2 (ja) 2015-07-29
MX2009012633A (es) 2011-05-24
EP2506016A2 (en) 2012-10-03
ES2549610T3 (es) 2015-10-29
JP2013511735A (ja) 2013-04-04
EP2506016B1 (en) 2015-07-08
US20130065239A1 (en) 2013-03-14

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