CN102740892A - 基于聚(dl-乳酸-乙醇酸共聚物)（plga）的用于光动力疗法（pdt）的纳米粒子载体系统 - Google Patents

基于聚(dl-乳酸-乙醇酸共聚物)（plga）的用于光动力疗法（pdt）的纳米粒子载体系统 Download PDF

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CN102740892A
CN102740892A CN2010800629259A CN201080062925A CN102740892A CN 102740892 A CN102740892 A CN 102740892A CN 2010800629259 A CN2010800629259 A CN 2010800629259A CN 201080062925 A CN201080062925 A CN 201080062925A CN 102740892 A CN102740892 A CN 102740892A
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nanoparticle
photosensitizer
plga
chlorin
photodynamic therapy
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Chinese (zh)
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克劳斯·兰格尔
托马斯·克诺布洛赫
比特·罗德
安格莱特·普鲁斯
沃科尔·阿尔布莱奇特
苏珊娜·格拉菲
阿诺·维厄
哈根·冯布里森
卡林·洛
西尔维娅·瓦格内
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Biolitec Investment Ii Co Ltd
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Beletech Pharmaceutical Market Co ltd
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Priority to CN201710128404.2A priority Critical patent/CN106913533A/zh
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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CN2010800629259A 2009-12-11 2010-12-08 基于聚(dl-乳酸-乙醇酸共聚物)（plga）的用于光动力疗法（pdt）的纳米粒子载体系统 Pending CN102740892A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710128404.2A CN106913533A (zh) 2009-12-11 2010-12-08 基于聚(dl‑乳酸‑乙醇酸共聚物)的用于光动力疗法的纳米粒子载体系统

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28589509P 2009-12-11 2009-12-11
US61/285,895 2009-12-11
US12/941,447 2010-11-08
US12/941,447 US20110275686A1 (en) 2009-12-11 2010-11-08 Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
PCT/US2010/059367 WO2011071970A2 (en) 2009-12-11 2010-12-08 Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)

Related Child Applications (1)

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CN201710128404.2A Division CN106913533A (zh) 2009-12-11 2010-12-08 基于聚(dl‑乳酸‑乙醇酸共聚物)的用于光动力疗法的纳米粒子载体系统

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CN2010800629259A Pending CN102740892A (zh) 2009-12-11 2010-12-08 基于聚(dl-乳酸-乙醇酸共聚物)（plga）的用于光动力疗法（pdt）的纳米粒子载体系统

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US (1) US20110275686A1 (enExample)
EP (1) EP2509633B1 (enExample)
JP (1) JP5868869B2 (enExample)
CN (2) CN106913533A (enExample)
BR (1) BR112012013951A2 (enExample)
CA (1) CA2784005C (enExample)
WO (1) WO2011071970A2 (enExample)

Cited By (6)

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CN103169968A (zh) * 2013-03-12 2013-06-26 中国科学院理化技术研究所 一种基于白蛋白的疏水二氢卟吩光敏剂纳米药物制剂、制备方法及其应用
CN103933568A (zh) * 2014-05-12 2014-07-23 南京师范大学 一种水溶性竹红菌素plga纳米粒及其制备方法
CN105343878A (zh) * 2015-11-30 2016-02-24 中国人民解放军第三军医大学第三附属医院 还原敏感型水溶性分子靶向光敏剂及其制备方法和应用
CN109481418A (zh) * 2017-12-19 2019-03-19 深圳先进技术研究院 抗肿瘤纳米颗粒及其制备方法和应用
CN111000804A (zh) * 2019-12-05 2020-04-14 东南大学 一种甘露糖靶向的热响应铂纳米颗粒及其制备方法和应用
CN113543810A (zh) * 2019-03-08 2021-10-22 北卡罗莱纳州立大学 光热疗法促进cart t细胞的肿瘤浸润和抗肿瘤活性

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US9211283B2 (en) * 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
GB0922066D0 (en) 2009-12-17 2010-02-03 Univ Belfast Modulator
WO2013012628A2 (en) * 2011-07-15 2013-01-24 The University Of Georgia Research Foundation, Inc. Immune-stimulating photoactive hybrid nanoparticles
JP2013094135A (ja) * 2011-11-02 2013-05-20 Waseda Univ 人工ナノ材料の安全性を評価する方法
US10188601B2 (en) * 2013-09-22 2019-01-29 Brenda Laster Continuous long-term controlled release of telomerase inhibitors
EP3201201B1 (en) 2014-09-30 2022-01-26 biolitec unternehmensbeteiligungs II AG Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
CN106620893B (zh) * 2015-07-23 2021-07-30 爱博诺德(北京)医疗科技股份有限公司 用于眼部疾病光治疗的材料
WO2017019792A1 (en) * 2015-07-27 2017-02-02 The Texas A&M University System Surface active nanosystems
EP3210626B1 (en) 2016-02-26 2024-11-27 biolitec Holding GmbH & Co KG Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy
EP3626268A1 (en) 2018-09-24 2020-03-25 Westfälische Wilhelms-Universität Münster Polymer-particle light-cleavable carrier systems for photodynamic therapy
WO2020120474A1 (en) 2018-12-10 2020-06-18 Universität Hamburg Specifically glyco-substituted porphyrins and chlorins for photodynamic therapy
US20250295815A1 (en) * 2021-04-07 2025-09-25 North Carolina State University Porphyrin-hydroporphyrin compounds, compositions comprising the same and methods of use thereof

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169968A (zh) * 2013-03-12 2013-06-26 中国科学院理化技术研究所 一种基于白蛋白的疏水二氢卟吩光敏剂纳米药物制剂、制备方法及其应用
CN103169968B (zh) * 2013-03-12 2014-11-26 中国科学院理化技术研究所 一种基于白蛋白的疏水二氢卟吩光敏剂纳米药物制剂、制备方法及其应用
CN103933568A (zh) * 2014-05-12 2014-07-23 南京师范大学 一种水溶性竹红菌素plga纳米粒及其制备方法
CN105343878A (zh) * 2015-11-30 2016-02-24 中国人民解放军第三军医大学第三附属医院 还原敏感型水溶性分子靶向光敏剂及其制备方法和应用
CN105343878B (zh) * 2015-11-30 2018-10-19 中国人民解放军第三军医大学第三附属医院 还原敏感型水溶性分子靶向光敏剂及其制备方法和应用
CN109481418A (zh) * 2017-12-19 2019-03-19 深圳先进技术研究院 抗肿瘤纳米颗粒及其制备方法和应用
CN113543810A (zh) * 2019-03-08 2021-10-22 北卡罗莱纳州立大学 光热疗法促进cart t细胞的肿瘤浸润和抗肿瘤活性
CN113543810B (zh) * 2019-03-08 2024-02-09 北卡罗莱纳州立大学 光热疗法促进cart t细胞的肿瘤浸润和抗肿瘤活性
CN111000804A (zh) * 2019-12-05 2020-04-14 东南大学 一种甘露糖靶向的热响应铂纳米颗粒及其制备方法和应用
CN111000804B (zh) * 2019-12-05 2022-02-11 东南大学 一种甘露糖靶向的热响应铂纳米颗粒及其制备方法和应用

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US20110275686A1 (en) 2011-11-10
BR112012013951A2 (pt) 2018-06-05
JP5868869B2 (ja) 2016-02-24
EP2509633C0 (en) 2025-06-18
CA2784005C (en) 2018-01-02
WO2011071970A2 (en) 2011-06-16
CA2784005A1 (en) 2011-06-16
JP2013513610A (ja) 2013-04-22
EP2509633B1 (en) 2025-06-18
EP2509633A4 (en) 2015-08-26
EP2509633A2 (en) 2012-10-17
CN106913533A (zh) 2017-07-04

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