CN102727758B - Traditional Chinese medicine enema for treating ulcerative colitis - Google Patents
Traditional Chinese medicine enema for treating ulcerative colitis Download PDFInfo
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention discloses a traditional Chinese medicine enema for treating ulcerative colitis, wherein traditional Chinese medical science holds that the ulcerative colitis belongs to the domain of 'diarrhoea', 'bloody stool' and 'dysentery', and the pathogenesis mostly is mainly caused by feeling six viruses of wind, cold, heat, dampness and dryness, having internal damage by excess of seven emotions and damaging spleen and stomach, constraining large intestine by the dampness and heat to obstruct the intestinal Qi function and injure the vein to cause blood and meat rot to emerge ulcer finally. Therefore, the traditional Chinese medicine enema provided by the invention chooses traditional Chinese medicines including japanese claw fern herb, caulis arcangelisiae, phellodendron bark, cordate houttuynia, folium glochidii eriocarpi, featherycleft horsegentian fruit, moutan bark, frankincense, bletilla striata, red halloysite and licorice root having functions of clearing away heat and toxicity, activating blood circulation and removing blood stasis and removing swelling and promoting granulation to process into the enema. After clinical tests in the hospital, the total efficiency reaches to 97.2%, the clinical symptom improvement is obviously superior to that of a contrast group, the side effect is low and the treatment cost is low. Therefore, the enema provided by the invention is suitable for clinical promotion and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicinal enema for the treatment of chronic ulcerative colitis.
Background technology
Ulcerative colitis is Digestive System Department commonly encountered diseases, frequently-occurring disease.The ulcerative colitis cause of disease is not yet fully clear and definite, and clinical main manifestations is diarrhoea, Mucous Stool or bloody purulent stool, stomachache and tenesmus, and its state of an illness weight does not wait, be the chronic course of disease more, still lack at present the radical treatment method, brought larger misery to the patient, and sickness rate is on the rise in recent years, doctor trained in Western medicine is to the treatment of ulcerative colitis, mainly concentrate on the oral administration, the general course for the treatment of is longer, and side effect is large, and repeatedly outbreak, be present one of comparatively thorny difficult and complicated illness clinically.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicinal enema for the treatment of ulcerative colitis, motherland's medical science thinks that ulcerative colitis belongs to the categories such as the traditional Chinese medical science " having loose bowels ", " intestinal is out-of-the-way ", " dysentery ", the cause of disease is many by experiencing the evil poison of six climate exopathogens, internal injury diet seven emotions, undermine taste, damp and hot under the pressure of large intestine, make intestinal mechanism of qi retardance, venation is impaired, blood loses the meat corruption, internal ulceration becomes infections.For this reason, Chinese traditional treatment should be take heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, detumescence and promoting granulation as the rule for the treatment of.
The objective of the invention is to be achieved through the following technical solutions, the Chinese medicinal enema of this treatment ulcerative colitis is made by the Chinese medicine of following weight portion: Herba Onychii japonici 10-15 part, Caulis Arcangelisiae 10-15 part, Cortex Phellodendri 15-20 part, Herba Houttuyniae 15-20 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 10-12 part, Radix Triostei Pinnatifidi 10-12 part, Cortex Moutan 10-15 part, Olibanum 10-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-20 part, Halloysitum Rubrum 10-12 part, Radix Glycyrrhizae 6-8 part.
Preferably, 13 parts of Herba Onychii japonicis, 13 parts of Caulis Arcangelisiaes, 18 parts of Cortex Phellodendris, 18 parts of Herba Houttuyniae, 11 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 11 parts of Radix Triostei Pinnatifidis, 12 parts of Cortex Moutans, 11 parts of Olibanums, 18 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 11 parts of Halloysitum Rubrums, 7 parts in Radix Glycyrrhizae.
Preparation method: add with automatic boiling-machine medicine-feeding that water is dense to be fried in shallow oil to 300ml, vacuum packaging, every bag of 150ml.
In the side: Herba Onychii japonici: return stomach, intestinal, bladder three warps; Clearing away heat-damp and promoting diuresis.
Caulis Arcangelisiae: GUIXIN, lung, large intestine channel; Clearing away heat-damp and promoting diuresis, eliminating fire and detoxication.
Cortex Phellodendri: return kidney, bladder, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever.
Herba Houttuyniae: return lung meridian; Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, relieving stranguria by diuresis.
Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi): return stomach, spleen, large intestine channel; Heat-clearing and toxic substances removing, removing dampness to relieve itching.
Radix Triostei Pinnatifidi: wind-damp dispelling, vital energy regualting and blood circulation-promoting, strengthening the spleen and stomach, anti-inflammatory analgesic, granulation promoting.
Cortex Moutan: GUIXIN, liver, stomach warp; Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis moves back steaming.
Olibanum: GUIXIN, liver, spleen channel; Promoting blood circulation and stopping pain, detumescence and promoting granulation.
The Pseudobulbus Bletillae (Rhizoma Bletillae): return lung, stomach, Liver Channel; Astringing to arrest bleeding, detumescence and promoting granulation.，
Halloysitum Rubrum: return large intestine, stomach warp; Relieving diarrhea with astringents, hemostasis, expelling pus and promoting granulation.
Radix Glycyrrhizae: GUIXIN, spleen, lung, stomach warp; Invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing is alleviated pain relieving, relaxes the property of medicine.
Clinical data
Physical data 144 routine patients are my inpatient of institute, all meet chronic enteritis diagnostic criteria [1].Be divided at random two groups, treatment group 72 examples, male 40 examples, women 32 examples; 34～67 years old age, average 44.7 ± 2.35 years old; The course of disease is at 4.5 months～6.5 years, average 4.15 ± 1.77 years.Matched group 72 examples, male 42 examples, women 30 examples; 35～69 years old age, average 45.2 ± 1.88 years old; The course of disease is at 4 months～7 years, average 4.35 ± 1.62 years.Two groups have comparability (P＞0.05) in data such as age, sex, the state of an illness, the courses of disease.
Diagnostic criteria: meet following condition person and be the treatment object of observation: (1) meets the ulcerative colitis diagnostic criteria that national chronic noninfective intestinal tract disease academic conference is formulated in 1993, and intestinal mirror and Histological Evidence are all arranged; (2) active stage: light, in, the severe case.Except the sulfanilamide allergy sufferers.
Therapeutic Method: treatment group is used Chinese medicinal enema of the present invention, after fully shaking up, extracts medicinal liquid 70ml at every turn, and fluid temperature and human body temperature are adapted to suitable, retention enema 1 time every night, is advised the emptying stool of patient before sleeping, left lateral position according to colonoscope finding pathological changes intestinal segment, is adjusted position.Matched group gives metronidazole injection 80ml and adds XILEI SAN 1.0g (Tongrentang Pharmaceutical Factory, Beijing's production) retention enema, 1 time every night.Two groups equal 7 days be a course for the treatment of.
Criterion of therapeutical effect: (1) cures in the recent period: ulcer heals fully, and intestinal mucosa is roughly normal, cicatrization, and inflammation disappears substantially, and subjective symptoms all disappears, and biopsy is that mononuclear cells infiltration is main, and stool routine examination checks negative; (2) effective: the ulcer ulcer area refers to that (ulcer major diameter) dwindles more than 50%, and intestinal mucosa mild inflammation or pseudopolyp form, and cardinal symptom disappears, but still has obvious inflammation, and stool routine examination checks negative; (3) invalid: the ulcer kitchen range dwindles below 50%, and subjective symptoms is without improvement, and inflammation has no and alleviates, and stool routine examination checks positive.
Curative effect relatively sees Table 1 after two groups of treatments two courses for the treatment of.
*P＜0.05，
On average the improvement time sees Table 2 to two groups of symptoms after two groups of treatments two courses for the treatment of.
Clinical and experimental result shows that enema of the present invention has anti-inflammation, promotes the good result of microcirculation, ulcer healing and inflammation material absorbing.
The specific embodiment
Embodiment one: take by weighing Herba Onychii japonici 13g, Caulis Arcangelisiae 13g, Cortex Phellodendri 18g, Herba Houttuyniae 18g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 11g, Radix Triostei Pinnatifidi 11g, Cortex Moutan 12g, Olibanum 11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 18g, Halloysitum Rubrum 11g, Radix Glycyrrhizae 7g, make according to a conventional method enema.Before the coloclysis, fully shake up rear each extraction medicinal liquid 70ml, fluid temperature and human body temperature are adapted to suitable, retention enema, 1 time every night.Advise the emptying stool of patient before sleeping, left lateral position according to colonoscope finding pathological changes intestinal segment, is adjusted position.
Embodiment two: take by weighing Herba Onychii japonici 10g, Caulis Arcangelisiae 10g, Cortex Phellodendri 15g, Herba Houttuyniae 15g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 10g, Radix Triostei Pinnatifidi 10g, Cortex Moutan 10g, Olibanum 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Halloysitum Rubrum 10g, Radix Glycyrrhizae 6g, make according to a conventional method enema.Before the coloclysis, fully shake up rear each extraction medicinal liquid 70ml, fluid temperature and human body temperature are adapted to suitable, retention enema, 1 time every night.Advise the emptying stool of patient before sleeping, left lateral position according to colonoscope finding pathological changes intestinal segment, is adjusted position.
Embodiment three: take by weighing Herba Onychii japonici 15g, Caulis Arcangelisiae 15g, Cortex Phellodendri 20g, Chara fragilis Desv. 20g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12g, Radix Triostei Pinnatifidi 12g, Cortex Moutan 15g, Olibanum 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Halloysitum Rubrum 12g, Radix Glycyrrhizae 8g, make according to a conventional method enema.Before the coloclysis, fully shake up rear each extraction medicinal liquid 70ml, fluid temperature and human body temperature are adapted to suitable, retention enema, 1 time every night.Advise the emptying stool of patient before sleeping, left lateral position according to colonoscope finding pathological changes intestinal segment, is adjusted position.
Claims (2)
1. Chinese medicinal enema for the treatment of ulcerative colitis is characterized in that this Chinese medicinal enema made by the Chinese medicine of following weight portion: Herba Onychii japonici 10-15 part, Caulis Arcangelisiae 10-15 part, Cortex Phellodendri 15-20 part, Herba Houttuyniae 15-20 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 10-12 part, Radix Triostei Pinnatifidi 10-12 part, Cortex Moutan 10-15 part, Olibanum 10-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-20 part, Halloysitum Rubrum 10-12 part, Radix Glycyrrhizae 6-8 part.
2. a kind of Chinese medicinal enema for the treatment of ulcerative colitis according to claim 1 is characterized in that this Chinese medicinal enema made by the Chinese medicine of following weight portion: 13 parts of Herba Onychii japonicis, 13 parts of Caulis Arcangelisiaes, 18 parts of Cortex Phellodendris, 18 parts of Herba Houttuyniae, 11 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 11 parts of Radix Triostei Pinnatifidis, 12 parts of Cortex Moutans, 11 parts of Olibanums, 18 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 11 parts of Halloysitum Rubrums, 7 parts in Radix Glycyrrhizae.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102988559B (en) * | 2012-12-04 | 2013-10-30 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN103211944B (en) * | 2013-03-22 | 2014-05-21 | 武传华 | Traditional Chinese medicine enema used for treating radiation enteritis |
| CN103768256A (en) * | 2014-01-12 | 2014-05-07 | 高芹凤 | Chinese herba preparation for treating chronic ulcerative colitis |
| CN104857329A (en) * | 2015-05-06 | 2015-08-26 | 青岛市市立医院 | Clysis liquid for curing ulcerative colitis |
| CN105250710A (en) * | 2015-11-06 | 2016-01-20 | 刘杰 | Traditional Chinese medicine enema for treating ulcerative colitis |
| CN105250612A (en) * | 2015-11-06 | 2016-01-20 | 刘亚辉 | Traditional Chinese medicine enema for treating ulcerative colitis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137399A (en) * | 1996-02-17 | 1996-12-11 | 王福运 | Traditional Chinese medicine for curing colitis and its preparing method and application |
| CN1203803A (en) * | 1997-12-25 | 1999-01-06 | 刘旭山 | Powder for curing ulcerative colitis and proctitis ulcerosa |
| CN101991793A (en) * | 2009-08-20 | 2011-03-30 | 张志通 | Medicine for treating nonspecific ulcerative colitis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1137399A (en) * | 1996-02-17 | 1996-12-11 | 王福运 | Traditional Chinese medicine for curing colitis and its preparing method and application |
| CN1203803A (en) * | 1997-12-25 | 1999-01-06 | 刘旭山 | Powder for curing ulcerative colitis and proctitis ulcerosa |
| CN101991793A (en) * | 2009-08-20 | 2011-03-30 | 张志通 | Medicine for treating nonspecific ulcerative colitis |
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