CN105250710A

CN105250710A - Traditional Chinese medicine enema for treating ulcerative colitis

Info

Publication number: CN105250710A
Application number: CN201510780904.5A
Authority: CN
Inventors: 刘杰; 匡永恒
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-06
Filing date: 2015-11-06
Publication date: 2016-01-20

Abstract

The invention discloses a traditional Chinese medicine enema for treating ulcerative colitis. The ulcerative colitis belongs to the category of dysentery in traditional Chinese medicine, the pathogenesis shows that wet can not be overcome due to spleen deficiency, damp-heat evil exists in a large intestine, Qi movement of intestinal tracts is affected, Qi stagnation and blood stasis are caused, and flesh is rotten to ulcers. Traditional Chinese medicines of radix arnebiae, twigs and leaves of manyflower supplejack, polygonum criopolitanum, herba siegesbeckiae, herbs of axillary balm, rhizome of Chinese twinleaf, tree-of-heaven ailanthus bark, herbs of creeping rattlesnake plantain, bark of Japanese pagodatree, stems of maximorwica waterchesnut and roots of Asia belltree are selected to be prepared into the enema. According to the clinical tests, the total effective rate reaches 96 percent.

Description

A kind of Chinese medicinal herbs decoction for the treatment of ulcerative colitis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicinal herbs decoction for the treatment of ulcerative colitis.

Background technology

Ulcerative colitis is the nonspecific colonitis disease that a kind of cause of disease is very not clear and definite, extent of disease involves section colon far away (particularly rectum and sigmoid colon) more, and pathological changes is mainly limited to colorectal mucosa and tela submucosa.Main clinical manifestation is stomachache, tenesmus, mucopurulent bloody stool, many recurrent exerbation or long-term delay are in chronic process, there is no special therapeutic method at present, it is generally acknowledged that total colonoscopy less than 60 centimetres pathological changes intestinal segments should select topical therapeutic to be main, doctor trained in Western medicine mainly uses pomegranate nitrogen sulfadiazine and glucocorticoid is oral or retention-enema treatment, but side effect is more, drug withdrawal easily repeatedly.Applicant is in clinical practice for many years, and utilize herbal enema administration to achieve good curative effect, medicine directly contacts with diseased region, reduce the first pass effect of liver, improve the availability of medicine, medicine in small intestinal, avoids the impact of the Digestive systems such as gastric acid on medicine without stomach, adopt the enema rectally of 38 ~ 41 DEG C, due to warm stimulation, cause intestinal mucosa vasodilation, promote local blood circulation, strengthen metabolism, improve nutrition and the whole body function of local organization.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicinal herbs decoction for the treatment of ulcerative colitis.Ulcerative colitis be suffer from abdominal pain, tenesmus, bloody purulent stool be primary symptom, belong to the traditional Chinese medical science " dysentery " category, primary disease acute stage, accumulates large intestine primarily of insufficiency of the spleen can not victory in wet, damp and hot heresy more, affects intestinal mechanism of qi and runs, cause qi depression to blood stasis, and meat corruption becomes infections.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicinal herbs decoction of this treatment ulcerative colitis is made up of the Chinese medicine of following weight portion: Radix Arnebiae (Radix Lithospermi) 6-10 part, Ramulus et folium berchemiae floribundae 6-10 part, Herba Polygoni gracilis 6-10 Fen, Herba Siegesbeckiae 11-15 part, Herba melissae axillaris 11-15 part, Rhizoma jeffersoniae dubiae 11-15 part, Cortex Ailanthi 9-14 part, Herba goodyearae repentis 9-14 part, Cortex sophorae 9-14 part, Calyx Trapae 9-14 part, Radix radermacherae sinicae 9-14 part.

Preferred: Radix Arnebiae (Radix Lithospermi) 8 parts, Ramulus et folium berchemiae floribundae 8 parts, Herba Polygoni gracilis 8 Fen, Herba Siegesbeckiae 13 parts, Herba melissae axillaris 13 parts, Rhizoma jeffersoniae dubiae 13 parts, Cortex Ailanthi 12 parts, Herba goodyearae repentis 12 parts, Cortex sophorae 12 parts, Calyx Trapae 12 parts, Radix radermacherae sinicae 12 parts.

Compound method: traditionally make enema.

Fang Zhong: Radix Arnebiae (Radix Lithospermi) removing heat from blood and promoting blood circulation, heat-clearing and toxic substances removing; Ramulus et folium berchemiae floribundae clearing away heat and cooling blood, diuresis removing toxic substances, detumescence are enriched blood; Herba Polygoni gracilis cold expelling is invigorated blood circulation; Herba Siegesbeckiae wind-damp dispelling, blood pressure lowering, relieving rigidity of muscles and joints, nourishing YIN and benefiting blood, pain relieving; Herba melissae axillaris heat-clearing and toxic substances removing; Rhizoma jeffersoniae dubiae heat-clearing and toxic substances removing, stomach invigorating antidiarrheal; The hemostasis of Cortex Ailanthi heat extraction dampness, astringing intestine to stop diarrhea, parasite killing; Herba goodyearae repentis heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, hard masses softening and resolving; Cortex sophorae expelling wind and removing dampness, reducing swelling and alleviating pain; Calyx Trapae controls ulcer; Radix radermacherae sinicae heat-clearing and toxic substances removing, eliminating stasis to stop pain.

Clinical data

1, the routine patients of ulcerative colitis of physical data 100 is all selected from my institute's inpatient in year August in July, 2009 to 2012.Wherein male 60 example, women 40 example; 58.5 years old mean age; Average course of disease 5.5 years, onset 34 example, chronic recurrent 50 example, Chronic persistent 16 example in 100 examples, clinical visible hypogastric region distending pain in various degree and diarrhoea.

2, Therapeutic Method: get Radix Arnebiae (Radix Lithospermi) 8g, Ramulus et folium berchemiae floribundae 8g, Herba Polygoni gracilis 8g, Herba Siegesbeckiae 13g, Herba melissae axillaris 13g, Rhizoma jeffersoniae dubiae 13g, Cortex Ailanthi 12g, Herba goodyearae repentis 12g, Cortex sophorae 12g, Calyx Trapae 12g, Radix radermacherae sinicae 12g, traditionally decocting extracting juice 240ml makes enema, and point early, evening twice is with the retention enema of rectum push injection.Concrete enema method: taking liquid 120ml, medicine temperature about 38 DEG C, after bowel relieving, patient gets left lateral position, anal 10 ~ 15 hoe is pushed into from anal canal is slow, get chest-knee position 20min after coloclysis, change 1 position after 20min, medicine is fully contacted with intestinal wall, retention enema liquid 3 ~ 4h, 15d are 1 course for the treatment of.

3, clinical indexes: symptom: stomachache, abdominal distention, times of defecation and character; Colonoscopy: the change situation of observing intestinal mucosa congestion and edema, ulcer; Medicine retention time: observe the medicine retention time after coloclysis: tracing study: all patients all carries out tracing study in 1.5 years after leaving hospital: untoward reaction.

4, curative effect determinate standard: cure: the transference cures such as stomachache, abdominal distention, diet improvement, times of defecation and part shape normal.Check intestinal mirror intestinal mucosa congestion and edema disappears, ulcer healing; Effective: symptom disappears substantially, stool is shaped, and check intestinal mirror intestinal mucosa congestion and edema is clearly better, and stain infections heals substantially; Take a turn for the better: symptom alleviates, check intestinal mirror endo enteritis alleviates and ulcer reduces; Invalid: symptom is without disappearance or alleviate and defecate abnormal, check intestinal mirror intestinal mucosa is congested without improving, and ulcer is without healing.

5, therapeutic outcome: after 100 routine patients of ulcerative colitis treat 2 courses for the treatment of, cure 60 examples (60%), effective 20 examples (20%), 16 examples that take a turn for the better (16%), invalid 4 examples (4%), total effective rate is 96%, it can thus be appreciated that the Chinese medicinal herbs decoction for the treatment of ulcerative colitis of the present invention is evident in efficacy.

Model case

Patient Wang, female, peasant is stain ulcer colitis through hospital diagnosis.Patient's emaciated physique, shallow complexion, dizzy, stomachache, tastelessness.Stool checks: pyocyte is a little, erythrocyte, mucosanguineous feces, and stool is cultivated, and fibercolonscopy, colon 14cm section mucosa, edema, dense blood, rectum 8-10cm place being dispersed in property of intestinal segment shallow stain infections, in enteric cavity, courageous and upright mucus secretion is many.With after two courses for the treatment of of Chinese medicinal herbs decoction enema treatment of the present invention, colitis symptoms disappears, and 1 year without recurrence.

Detailed description of the invention

Embodiment one: take Radix Arnebiae (Radix Lithospermi) 6g, Ramulus et folium berchemiae floribundae 6g, Herba Polygoni gracilis 6g, Herba Siegesbeckiae 11g, Herba melissae axillaris 11g, Rhizoma jeffersoniae dubiae 11g, Cortex Ailanthi 9g, Herba goodyearae repentis 9g, Cortex sophorae 9g, Calyx Trapae 9g, Radix radermacherae sinicae 9g, traditionally make enema.

Embodiment two: get Radix Arnebiae (Radix Lithospermi) 8g, Ramulus et folium berchemiae floribundae 8g, Herba Polygoni gracilis 8g, Herba Siegesbeckiae 13g, Herba melissae axillaris 13g, Rhizoma jeffersoniae dubiae 13g, Cortex Ailanthi 12g, Herba goodyearae repentis 12g, Cortex sophorae 12g, Calyx Trapae 12g, Radix radermacherae sinicae 12g, traditionally make enema.

Embodiment three: take Radix Arnebiae (Radix Lithospermi) 10g, Ramulus et folium berchemiae floribundae 10g, Herba Polygoni gracilis 10g, Herba Siegesbeckiae 15g, Herba melissae axillaris 15g, Rhizoma jeffersoniae dubiae 15g, Cortex Ailanthi 14g, Herba goodyearae repentis 14g, Cortex sophorae 14g, Calyx Trapae 14g, Radix radermacherae sinicae 14g, traditionally make enema.

Claims

1. treat a Chinese medicinal herbs decoction for ulcerative colitis, it is characterized in that this Chinese medicinal herbs decoction is made up of the Chinese medicine of following weight portion: Radix Arnebiae (Radix Lithospermi) 6-10 part, Ramulus et folium berchemiae floribundae 6-10 part, Herba Polygoni gracilis 6-10 part, Herba Siegesbeckiae 11-15 part, Herba melissae axillaris 11-15 part, Rhizoma jeffersoniae dubiae 11-15 part, Cortex Ailanthi 9-14 part, Herba goodyearae repentis 9-14 part, Cortex sophorae 9-14 part, Calyx Trapae 9-14 part, Radix radermacherae sinicae 9-14 part.

2. a kind of Chinese medicinal herbs decoction for the treatment of stain ulcer colitis as claimed in claim 1, is characterized in that this Chinese medicinal herbs decoction is made up of the Chinese medicine of following weight portion: Radix Arnebiae (Radix Lithospermi) 8 parts, Ramulus et folium berchemiae floribundae 8 parts, Herba Polygoni gracilis 8 Fen, Herba Siegesbeckiae 13 parts, Herba melissae axillaris 13 parts, Rhizoma jeffersoniae dubiae 13 parts, Cortex Ailanthi 12 parts, Herba goodyearae repentis 12 parts, Cortex sophorae 12 parts, Calyx Trapae 12 parts, Radix radermacherae sinicae 12 parts.