CN102696888B

CN102696888B - Feed mycotoxin removing agent

Info

Publication number: CN102696888B
Application number: CN2012101954605A
Authority: CN
Inventors: 张君超; 刘法成
Original assignee: ZHENGZHOU FENGYUAN BIOLOGICAL TECHNOLOGY CO LTD
Current assignee: ZHENGZHOU FENGYUAN BIOLOGICAL TECHNOLOGY CO LTD
Priority date: 2012-06-13
Filing date: 2012-06-13
Publication date: 2013-06-19
Anticipated expiration: 2032-06-13
Also published as: CN102696888A

Abstract

The invention relates to a feed mycotoxin removing agent. The feed mycotoxin removing agent comprises the following components in mass percentage: 20-30% of nano-sized montmorillonite, 20-30% of yeast cell wall polysaccharide, 5-10% of glucose oxidase, 3-5% of potassium chloride, 3-5% of vitamin E, 4-5% of vitamin C, 15-20% of glucose and 8-10% of compound Chinese herbal extract powder, wherein the compound Chinese herbal extract powder is compounded by Astragalus extract, rhubarb extract, licorice extract and Eucommia extract powder in a mass ratio of 1: 0.8-1.2: 0.8-1.2: 0.8-1.2. The feed mycotoxin removing agent can effectively avoid damage of mycotoxin to production performance and reproductive performance of animals and has a wide application prospect.

Description

A kind of mycotoxins in feed removes agent

Technical field

The invention belongs to feed additive field, be specifically related to a kind of additive to mycotoxin eliminating feed gas defence detoxifcation, the present invention uses as a kind of feed addictive, can effectively remove the mycotoxin in feed, the noxious material that mycotoxin in animal body is caused has certain detoxifcation, functions of expelling toxin.Have and alleviate mycotoxin to the harm of animal health and growth, improve it and produce and the beneficial effect of reproductive performance.Effectively improve the cultivation return rate.

Background technology

As everyone knows, various agricultural product all contain various moulds, and these moulds can produce mycotoxin, and mycotoxin is poisonous compound, and some even can be carcinogenic.Mycotoxin has a variety of, as various mycetogenetic mycotoxins: aflatoxin, fumidil, ochratoxin, vomitoxin, Zhan's mycotoxin of penicillium, zearalenone etc.

If by mould contamination, eliminate in not meeting of mould in storage and feed process when agricultural product and herbage are as feedstuff in a large number, understand along with feed enters in animal body, and then enter in human body through animal body, thus the health that jeopardizes the mankind.Mycotoxin can cause liver cancer, ephrosis (aflatoxins, mycin A, mycin B1), the cancer of the esophagus etc., and is very big to harm.

For the feedstuff that does not go mouldy and feed, can carry out mildew-resistant with the mould inhibitor that the Ministry of Agriculture allows to add, this class mould inhibitor comprises formic acid, butyric acid, propionic acid, fumaric acid etc.

And for the feed that has gone mouldy, mildew-resistant has lost meaning, can only take off mouldly, and main method has: mixed diluting method, chemical degradation, vivo degradation, mechanical degradation, physics detoxification etc., mould method is consuming time, consumption power and dangerous but these take off, and effect is not remarkable.

Therefore, developing a kind of new compound multiple-effect feed and take off mould additive, under present scale standard cultivation situation, is particular importance.

Summary of the invention

The purpose of this invention is to provide a kind of mycotoxin and remove agent, elimination contains the mycotoxin feed to pollution and the murder by poisoning of animal body body from every side, improves growth of animal performance and reproductive performance, improves animal body immunity, guarantees the health of animal.

Technical scheme of the present invention is: a kind of mycotoxins in feed removes agent, and its mass percent is composed as follows:

1. nano montmorillonite 20%-30%

2. yeast cell wall polysaccharide 20%-30%

3. glucose oxidase 5%-10%

4. potassium chloride 3%-5%

5. vitamin E 3%-5%

6. vitamin C 4%-5%

7. glucose 15%-20%

8. Chinese medical extract compound powder 8%-10%

Described Chinese medical extract compound powder is composited by Astragalus Root P.E, Chinese rhubarb extract, licorice, eucommia ulmoides extracts pulvis, and each constituent mass portion rate is Astragalus Root P.E: Chinese rhubarb extract: licorice: eucommia ulmoides extracts=1:0.8-1.2:0.8-1.2:0.8-1.2.Each component of the present invention has following effect:

1, nano montmorillonite:

(1) good gastric mucosa protective agent;

(2) well take off mould effect: mycotoxin is had stronger adsorptivity effect, and the adsorption rate of 100% pair of various toxin of adsorption rate is as follows:

Aflatoxin 100%, zearalenone 87%, ochratoxin 70%, ergotinine 100%,, fumonism 91%;

(3) hemostasis good medicine.

2, yeast cell wall polysaccharide:

(1) superpower absorbing mycotoxin ability

(2) remove enteric pathogenic bacteria, reduce enteron aisle toadstool and pathogen quantity

(3) excitation immunity

3, glucose oxidase:

The integrality of mycotoxin meeting heavy damage intestinal epithelial cell.The prothetic group flavin adenine dinucleotide (FAD) (FAD) of glucose oxidase but in the cellular respiration metabolism redox reaction of catalytic specie; has the multiple physiological effect; can remove free radical, the intestinal epithelial cell that watches for animals is complete, has removed the destruction of mycotoxin.Thereby play the effect of mould fungus inhibition and detoxifcation.

4, KCL: keep electrolyte balance;

5, VE: antioxidant extends cell life;

6, VC: antioxidant, function of detoxification improves immunity;

7, Chinese medical extract: wherein:

(1) Radix Glycyrrhizae: invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing;

(2) rheum officinale: antibacterial, anti-oxidant, protection liver pancreas, improve immunity of organisms;

(3) bark of eucommia: filling liver kidney, strengthening the bones and muscles;

(4) Radix Astragali: strengthen immunity, antiviral, additional physical efficiency.

The present invention has through experiment use repeatedly the immunity that strengthens animal, alleviates mycotoxin to the infringement of animal, improves animal and produces and reproductive performance, improves the effect of the performance of animal food safety.And it is simple that the present invention takes off mould agent and process for producing same, easy to operate, is easy to promote.

The specific embodiment

The present invention's " mycotoxins in feed removes agent " comprising: nano montmorillonite, yeast cell wall polysaccharide, glucose oxidase, KCL, VE, VC, glucose, traditional Chinese medicine extraction compound powder.

Its mass percent is composed as follows:

1. nano montmorillonite 20%-30%

2. yeast cell wall polysaccharide 20%-30%

3. glucose oxidase 5%-10%

4. potassium chloride 3%-5%

5. vitamin E 3%-5%

6. vitamin C 4%-5%

7. glucose 15%-20%

8. Chinese medical extract compound powder 8%-10%

Described Chinese medical extract compound powder is composited by Astragalus Root P.E, Chinese rhubarb extract, licorice, eucommia ulmoides extracts pulvis, and each constituent mass portion rate is Astragalus Root P.E: Chinese rhubarb extract: licorice: eucommia ulmoides extracts=1:0.8-1.2:0.8-1.2:0.8-1.2.

Above Chinese medical extract extracts with hot reflux; adopt the method for alcohol extracting; wait respectively and measure four kinds of Chinese medicine material medicines; the Radix Astragali, rheum officinale, the bark of eucommia, Radix Glycyrrhizae, feed intake respectively (crude drug source is from the wholesale base of Yuzhou of Henan Chinese medicine) uses convertible extractor (model H2-TQG) that Shanghai brightness exhibition experimental facilities Co., Ltd produces in former material and the ratio of water quality than 1:10; the employing normal pressure extracts; temperature is 100 ℃ and adds thermal distillation, and extraction time is 8-12 hour, and liquid is fully separated out.Technological process comprises step:

Feed intake, extract (alcohol extracting), separate (screen cloth separation), concentrate (evaporation and concentration, spray-drying.The equipment that can use Shanghai brightness exhibition experimental facilities Co., Ltd to produce, cleanliness factor is no less than 300,000 grades.

The manufactured goods index is as follows:

Astragalus Root P.E: contain 70% astragalus polyose

Chinese rhubarb extract: contain 28% rhubarb anthraquinones component

Licorice: contain 30% glycyrrhizic acid

Eucommia ulmoides extracts: contain 25% chlorogenic acid

But each Chinese medical extract also business is bought.

Implement 1:

1. nano montmorillonite 30%

2. the yeast cell wall polysaccharide 20%

3. glucose oxidase 10%

④KCL 5%

⑤VE 5%

⑥VC 5%

7. glucose 15%

8. the traditional Chinese medicine extraction compound 10%, wherein 4 kinds of quality proportionings such as Chinese medical extract.

Getting the mycotoxins in feed of making according to the above ratio removes agent and processes feed and carry out the pig check experiment of feeding.Choose the vulva redness is arranged, 20 of sows that out of heat, false pregnancy symptom is detained in prolapsus, corpus luteum, be divided at random 2 groups; Get obviously mouldy feed, wherein one group is control group, the feed that Direct-fed is mouldy, and another group is the feed feed of additive of the present embodiment of interpolation 3/1000ths of experimental group, after feeding 7-15 days, experimental group sow symptom all disappears, and oestruses; The control group sx↑.

Implement 2:

1. nano montmorillonite 20%

2. the yeast cell wall polysaccharide 30%

3. glucose oxidase 5%

④KCL 5%

⑤VE 5%

⑥VC 5%

7. glucose 20%

Getting the mycotoxins in feed of making according to the above ratio removes agent and processes feed and carry out the pig check experiment of feeding.Get slight mouldy feed and be used for experiment.Choose 20 of the sows of post-coitum, be divided at random 2 groups; Wherein one group is control group, the slight mouldy feed of Direct-fed, and another group is experimental group, the feed feed of the additive that adds the present embodiment of 2/1000ths, after feeding 7-15 days, experimental group sow upgrowth situation is good, the hair color light, miscarriage and stillborn foetus do not occur; In control group, all the sow growth is bad, and hair color is dark and gloomy, and 3 miscarriages are wherein arranged.

Implement 3:

1. nano montmorillonite 30%

2. the cell wall polysaccharides 30% of yeast

3. glucose oxidase 5%

④KCL 3%

⑤VE 3%

⑥VC 4%

7. glucose 15%

Getting the mycotoxins in feed of making according to the above ratio removes agent and processes feed and carry out the pig check experiment of feeding.Get normal funginert rule feed appropriate, choose 60 of growing and fattening pigs, be divided at random 2 groups; Wherein one group is control group, this conventional feed of Direct-fed, another group is experimental group, the feed of the additive of the present embodiment of the interpolation 1/1000th of feeding, after feeding 30 days, experimental group sow upgrowth situation is good, the hair color light, and feed intake is higher than control group 5%, the body weight increase is on average higher than control group 8%, in control group, all the sow growth is bad, and hair color is dark and gloomy, and feed intake and weightening finish are lower than experimental group.

Also to the pig of various ill symptomses is arranged, such as feed intake reduces, weightening finish descends the inventor, growth retardation, jaundice, the Chronic Liver dysfunction, the serum sphingolipid changes, liver tissue injury, the pig of the various symptoms such as acute pulmonary edema, the feed of the additive that added above-described embodiment of feeding has all been received the raising feed intake, speed of weight increment improves, the effect that the rate of falling ill reduces.

As the animal feed additive routine use, by mass percentage 1%---2% adds in animal feed, but mould fungus inhibition growth, prevent that feed is mouldy, thereby eliminate mycotoxin to the affects on the growth of animal, improve the immunity of animal, reduce the incidence of disease, improve the Growth and reproduction performance of animal.

Claims

1. a mycotoxins in feed removes agent, it is characterized in that its mass percent is composed as follows:

2. mycotoxins in feed claimed in claim 1 removes agent, it is characterized in that described Chinese medical extract compound powder is compound for mass ratioes such as each components.

3. the described mycotoxins in feed of claim 1 or 2 removes agent, it is characterized in that its mass percent is composed as follows:

4. the described mycotoxins in feed of claim 1 or 2 removes agent, it is characterized in that its mass percent is composed as follows:

5. the described mycotoxins in feed of claim 1 or 2 removes agent, it is characterized in that its mass percent is composed as follows: