CN102686747A - 使用探针杂交和限制性通过信号扩大而检测靶核酸的方法 - Google Patents
使用探针杂交和限制性通过信号扩大而检测靶核酸的方法 Download PDFInfo
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- CN102686747A CN102686747A CN2010800606469A CN201080060646A CN102686747A CN 102686747 A CN102686747 A CN 102686747A CN 2010800606469 A CN2010800606469 A CN 2010800606469A CN 201080060646 A CN201080060646 A CN 201080060646A CN 102686747 A CN102686747 A CN 102686747A
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/6813—Hybridisation assays
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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| PCT/US2010/057781 WO2011063388A2 (en) | 2009-11-23 | 2010-11-23 | Assay method for target nucleic acid by signal amplification using probe hybridization and restriction |
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| CN102686747A true CN102686747A (zh) | 2012-09-19 |
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| JP (1) | JP2013511292A (enExample) |
| CN (1) | CN102686747A (enExample) |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105555969A (zh) * | 2013-06-18 | 2016-05-04 | Lgc有限公司 | 具有通用元件的基于荧光团的寡核苷酸探针 |
| CN108707652A (zh) * | 2013-12-02 | 2018-10-26 | 苏州新波生物技术有限公司 | 核酸探针和检测基因组片段的方法 |
| CN110730825A (zh) * | 2017-05-23 | 2020-01-24 | 新泽西鲁特格斯州立大学 | 用双相互作用发夹探针进行的靶标介导的原位信号放大 |
| CN113637728A (zh) * | 2014-08-11 | 2021-11-12 | 卢米耐克斯公司 | 用于在核酸测定中改善解链分辨和多重性的探针 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2772123C (en) | 2009-08-31 | 2018-03-06 | The Governors Of The University Of Alberta | Binding-induced hairpin detection system |
| US9603949B2 (en) | 2011-09-01 | 2017-03-28 | University Of Iowa Research Foundation | Oligonucleotide-based probes for detection of bacterial nucleases |
| JP2015508655A (ja) * | 2012-02-14 | 2015-03-23 | コーネル ユニバーシティー | 組み合わせたヌクレアーゼ反応、連結反応、およびポリメラーゼ反応を用いて核酸配列、発現、またはコピー変化を相対的に定量するための方法 |
| GB201217770D0 (en) * | 2012-10-04 | 2012-11-14 | Base4 Innovation Ltd | Biological probes and the use thereof |
| EP3102704B1 (en) | 2014-02-07 | 2020-02-12 | University of Iowa Research Foundation | Oligonucleotide-based probes and methods for detection of microbes |
| US10947588B2 (en) | 2014-06-19 | 2021-03-16 | Multiplicom N.V. | Restriction mediated quantitative polymerase chain reactions |
| WO2016141040A1 (en) * | 2015-03-02 | 2016-09-09 | The Regents Of The University Of California | Homogenous entropy-driven biomolecular assay (heba) |
| JP2018526009A (ja) * | 2015-09-03 | 2018-09-13 | ナノストリング テクノロジーズ，インコーポレイティド | ヌクレオチド１個の分解能を有する多価プローブ |
| ITUB20155686A1 (it) * | 2015-11-18 | 2017-05-18 | Fondazione St Italiano Tecnologia | Procedimento di rivelazione di acidi nucleici e relativo kit. |
| ITUB20155706A1 (it) * | 2015-11-18 | 2017-05-18 | Fondazione St Italiano Tecnologia | Procedimento di rivelazione di acidi nucleici e relativo kit. |
| CN109790566A (zh) * | 2016-09-20 | 2019-05-21 | 贝斯4创新公司 | 单核苷酸检测方法及相关的探针 |
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| CN105555969A (zh) * | 2013-06-18 | 2016-05-04 | Lgc有限公司 | 具有通用元件的基于荧光团的寡核苷酸探针 |
| CN108707652A (zh) * | 2013-12-02 | 2018-10-26 | 苏州新波生物技术有限公司 | 核酸探针和检测基因组片段的方法 |
| CN108707652B (zh) * | 2013-12-02 | 2022-04-15 | 苏州新波生物技术有限公司 | 核酸探针和检测基因组片段的方法 |
| CN113637728A (zh) * | 2014-08-11 | 2021-11-12 | 卢米耐克斯公司 | 用于在核酸测定中改善解链分辨和多重性的探针 |
| CN113637728B (zh) * | 2014-08-11 | 2025-04-29 | 卢米耐克斯公司 | 用于在核酸测定中改善解链分辨和多重性的探针 |
| CN110730825A (zh) * | 2017-05-23 | 2020-01-24 | 新泽西鲁特格斯州立大学 | 用双相互作用发夹探针进行的靶标介导的原位信号放大 |
| CN110730825B (zh) * | 2017-05-23 | 2023-08-11 | 新泽西鲁特格斯州立大学 | 用双相互作用发夹探针进行的靶标介导的原位信号放大 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011063388A3 (en) | 2011-10-20 |
| US8916349B2 (en) | 2014-12-23 |
| US20120322067A1 (en) | 2012-12-20 |
| JP2013511292A (ja) | 2013-04-04 |
| EP2504453A4 (en) | 2013-07-17 |
| EP2504453A2 (en) | 2012-10-03 |
| WO2011063388A2 (en) | 2011-05-26 |
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