CN102665684A - 用于吸入的组合物 - Google Patents
用于吸入的组合物 Download PDFInfo
- Publication number
- CN102665684A CN102665684A CN2010800478259A CN201080047825A CN102665684A CN 102665684 A CN102665684 A CN 102665684A CN 2010800478259 A CN2010800478259 A CN 2010800478259A CN 201080047825 A CN201080047825 A CN 201080047825A CN 102665684 A CN102665684 A CN 102665684A
- Authority
- CN
- China
- Prior art keywords
- calcium
- composition
- zinc
- salt
- metal ion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0918450.8A GB0918450D0 (en) | 2009-10-21 | 2009-10-21 | Composition |
| GB0918450.8 | 2009-10-21 | ||
| PCT/GB2010/001955 WO2011048379A2 (en) | 2009-10-21 | 2010-10-21 | Composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102665684A true CN102665684A (zh) | 2012-09-12 |
Family
ID=41426476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800478259A Pending CN102665684A (zh) | 2009-10-21 | 2010-10-21 | 用于吸入的组合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130004542A1 (enExample) |
| EP (1) | EP2490670B1 (enExample) |
| JP (1) | JP2013508344A (enExample) |
| CN (1) | CN102665684A (enExample) |
| CA (1) | CA2777899C (enExample) |
| GB (1) | GB0918450D0 (enExample) |
| WO (1) | WO2011048379A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113163843A (zh) * | 2018-11-01 | 2021-07-23 | 尼科创业贸易有限公司 | 凝胶和结晶粉末 |
| CN115046816A (zh) * | 2022-03-11 | 2022-09-13 | 桂林优利特医疗电子有限公司 | 一种尿液有形成分分析仪用结晶质控物的制备方法 |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| PT2410981T (pt) | 2009-03-26 | 2017-05-25 | Pulmatrix Inc | Formulações em pó seco e métodos para tratar doenças pulmonares |
| GB0908129D0 (en) * | 2009-05-12 | 2009-06-24 | Innovata Ltd | Composition |
| AU2011296343B2 (en) | 2010-08-30 | 2015-12-10 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| US20130164338A1 (en) | 2010-08-30 | 2013-06-27 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| PT2621488T (pt) | 2010-09-29 | 2019-02-12 | Pulmatrix Operating Co Inc | Pós secos catiónicos |
| CA3086367A1 (en) | 2010-09-29 | 2012-04-05 | Pulmatrix Operating Company, Inc. | Monovalent metal cation dry powders for inhalation |
| WO2014007773A1 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Compositions comprising muscarinic receptor antagonist and sorbitol |
| CN104487075A (zh) | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
| US10105316B2 (en) | 2012-07-05 | 2018-10-23 | Arven llac Sanayi Ve Ticaret A.S. | Inhalation compositions comprising muscarinic receptor antagonist |
| WO2014007772A2 (en) | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising glucose anhydrous |
| WO2014007768A1 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Dry powder inhaler compositions comprising long acting muscorinic antagonists |
| US20150174064A1 (en) * | 2012-07-05 | 2015-06-25 | Arven IIac Sanayi Ve Ticaret A.S. | Compositions comprising muscarinic receptor antagonist and glucose anhydrous |
| WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
| EA201591218A1 (ru) * | 2012-12-27 | 2015-11-30 | Майкродоуз Терапьютикс, Инк. | Способы и композиции для введения оксибутинина |
| CN104885172B (zh) * | 2012-12-27 | 2019-12-13 | 3M创新有限公司 | 电化学装置及其制造方法 |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| JP2015116367A (ja) * | 2013-12-19 | 2015-06-25 | 重人 下山 | 寝具装置、寝具装置制御方法及びプログラム |
| CN103830194A (zh) * | 2014-03-11 | 2014-06-04 | 熊妲妮 | 茚达特罗固体分散体及含有其的药物组合物 |
| CA2965759C (en) | 2014-10-31 | 2023-12-12 | Glaxosmithkline Intellectual Property Development Limited | Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials |
| WO2017100656A1 (en) * | 2015-12-11 | 2017-06-15 | Otitopic Inc. | Dry powder formulations of aspirin for inhalation |
| JP7334983B2 (ja) * | 2018-01-11 | 2023-08-29 | エンフィスィーマ ソリューションズ ベスローテン フェンノートシャップ | 肺気腫及びその他の形態のcopdの治療のための組成物及び方法 |
| AU2022410611A1 (en) * | 2021-12-16 | 2024-07-18 | Alveolus Bio, Inc. | Spray dried inhalable biotherapeutics for the treatment of disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998016205A2 (en) * | 1996-10-17 | 1998-04-23 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8802174D0 (en) * | 1988-02-01 | 1988-03-02 | Quadrant Bioresources Ltd | Method of drying macromolecules |
| WO1990011756A1 (en) | 1989-04-12 | 1990-10-18 | Aberdeen University | Slow release vitreous systems |
| GB9107628D0 (en) | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| EP0563455A1 (en) | 1992-03-31 | 1993-10-06 | Purac Biochem B.V. | Particulate solid products containing a lump forming inhibitor |
| ATE222754T1 (de) * | 1992-06-12 | 2002-09-15 | Teijin Ltd | Ultrafeines pulver zur inhalation und dessen herstellung |
| ATE264096T1 (de) | 1994-03-07 | 2004-04-15 | Nektar Therapeutics | Verfahren und mittel zur verabreichung von insulin über die lunge |
| JP3414539B2 (ja) * | 1994-05-11 | 2003-06-09 | 有限会社ドット | 経鼻吸収用組成物 |
| JP3095624B2 (ja) | 1994-07-19 | 2000-10-10 | 株式会社ボッシュオートモーティブシステム | 積層型熱交換器の偏平チューブのろう付け方法 |
| FI970867A7 (fi) | 1994-08-04 | 1997-04-08 | Quadrant Drug Delivery Ltd | Kiinteät, annostelusysteemit hallittua vapautumista varten, joihin sys teemeihin molekyylit on sisällytetty ja menetelmät niiden valmistamise ksi |
| GB9423419D0 (en) | 1994-11-19 | 1995-01-11 | Andaris Ltd | Preparation of hollow microcapsules |
| CZ391297A3 (cs) | 1995-06-07 | 1998-05-13 | Quadrant Holdings Cambridge Limited | Způsob přípravy tenké porovité skelné matrice a prostředek tím získaný |
| US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| GB9621825D0 (en) | 1996-10-19 | 1996-12-11 | Andaris Ltd | Microparticles and their use as therapeutic vehicles |
| WO1999047174A1 (en) | 1998-03-18 | 1999-09-23 | Cambridge Biostability Limited | Amorphous glasses for stabilising sensitive products |
| DK1131059T3 (da) | 1998-11-13 | 2003-06-30 | Jago Res Ag | Tørpulver til inhalation |
| EP1158958B1 (en) | 1999-03-05 | 2007-06-06 | CHIESI FARMACEUTICI S.p.A. | Improved powdery pharmaceutical compositions for inhalation |
| UA75375C2 (en) | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| DE10050995A1 (de) | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | Neue Anticholinergika, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE10050994A1 (de) | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung |
| US20020141946A1 (en) * | 2000-12-29 | 2002-10-03 | Advanced Inhalation Research, Inc. | Particles for inhalation having rapid release properties |
| DE10141376A1 (de) | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Inhalationspulvern |
| DE10141377A1 (de) | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
| JP2003062074A (ja) * | 2001-08-29 | 2003-03-04 | Tomohiko Hashiba | 吸入装置 |
| DE10203749A1 (de) | 2002-01-31 | 2003-08-14 | Boehringer Ingelheim Pharma | Neue Anticholinergika, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| DE10203741A1 (de) | 2002-01-31 | 2003-08-14 | Boehringer Ingelheim Pharma | Neue Fluorencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| DE10203753A1 (de) | 2002-01-31 | 2003-08-14 | Boehringer Ingelheim Pharma | Neue Xanthencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| EP1480996A1 (en) * | 2002-02-04 | 2004-12-01 | Glaxo Group Limited | Amorphous fluticasone 2-furoate, pharmaceutical compositions thereof and its conversion to the crystalline unsolvated form |
| CA2478327A1 (en) | 2002-03-20 | 2003-10-02 | Advanced Inhalation Research, Inc. | Hgh (human growth hormone) formulations for pulmonary administration |
| AU2003291527A1 (en) | 2002-12-31 | 2004-07-29 | Nektar Therapeutics | Antibody-containing particles and compositions |
| JP2005060330A (ja) * | 2003-08-18 | 2005-03-10 | Tomohiko Hashiba | 球状タンパク質粉体とその製造方法 |
| GB0520794D0 (en) * | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
| PT2410981T (pt) * | 2009-03-26 | 2017-05-25 | Pulmatrix Inc | Formulações em pó seco e métodos para tratar doenças pulmonares |
| US20120083531A1 (en) * | 2009-03-26 | 2012-04-05 | Clarke Robert W | Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining |
-
2009
- 2009-10-21 GB GBGB0918450.8A patent/GB0918450D0/en not_active Ceased
-
2010
- 2010-10-21 JP JP2012534763A patent/JP2013508344A/ja active Pending
- 2010-10-21 CN CN2010800478259A patent/CN102665684A/zh active Pending
- 2010-10-21 WO PCT/GB2010/001955 patent/WO2011048379A2/en not_active Ceased
- 2010-10-21 EP EP10781721.5A patent/EP2490670B1/en not_active Not-in-force
- 2010-10-21 US US13/501,303 patent/US20130004542A1/en not_active Abandoned
- 2010-10-21 CA CA2777899A patent/CA2777899C/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998016205A2 (en) * | 1996-10-17 | 1998-04-23 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113163843A (zh) * | 2018-11-01 | 2021-07-23 | 尼科创业贸易有限公司 | 凝胶和结晶粉末 |
| CN115046816A (zh) * | 2022-03-11 | 2022-09-13 | 桂林优利特医疗电子有限公司 | 一种尿液有形成分分析仪用结晶质控物的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2777899C (en) | 2016-03-29 |
| GB0918450D0 (en) | 2009-12-09 |
| WO2011048379A3 (en) | 2012-01-05 |
| EP2490670A2 (en) | 2012-08-29 |
| WO2011048379A2 (en) | 2011-04-28 |
| JP2013508344A (ja) | 2013-03-07 |
| EP2490670B1 (en) | 2019-04-17 |
| CA2777899A1 (en) | 2011-04-28 |
| US20130004542A1 (en) | 2013-01-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102665684A (zh) | 用于吸入的组合物 | |
| ES3033142T3 (en) | Dry powder formulation comprising a phosphodiesterase inhibitor | |
| RS65494B1 (sr) | Kombinacije antagonista muskarinskog receptora i agonista beta-2-adrenoreceptora | |
| CA2803418A1 (en) | Dry powder formulation comprising an antimuscarinic drug | |
| JP2015519394A (ja) | キシナホ酸サルメテロール、プロピオン酸フルチカゾンおよび臭化チオトロピウムを含む吸入製剤用ドライパウダー、ならびにその製造方法 | |
| US20040062719A1 (en) | Particulate inhalation carrier | |
| KR102330428B1 (ko) | 흡입 제형용 건조 분말 및 이의 제조방법 | |
| CN105338967A (zh) | 包含布地奈德和福莫特罗的药物组合物 | |
| EP2821062A1 (en) | Novel dry powder inhaler formulations | |
| CN111481550A (zh) | 含有噻托溴铵和阿福特罗的药物制剂 | |
| KR102696616B1 (ko) | 흡입 제형용 건조 분말 및 이의 제조방법 | |
| KR102898819B1 (ko) | 흡입용 건조 분말 제제를 위한 신규 담체 입자 | |
| JP7712916B2 (ja) | 吸入用乾燥粉末製剤のための新規担体粒子 | |
| RU2823554C1 (ru) | Новые частицы носителя для сухих порошковых составов для ингаляции | |
| RU2795231C2 (ru) | Новые частицы носителя для сухих порошковых составов для ингаляции | |
| HK40064779A (en) | Novel carrier particles for dry powder formulations for inhalation | |
| CN112469443A (zh) | 用于吸入用干粉制剂的新型载体颗粒 | |
| HK40037203A (en) | Novel carrier particles for dry powder formulations for inhalation | |
| HK1239571A1 (en) | Dry powder formulation comprising a phosphodiesterase inhibitor | |
| TW201618759A (zh) | 具有經改善之組合型活性成分之穩定性的吸入型調配物乾粉末 | |
| HK1182002A (en) | Dry powder formulation comprising a phosphodiesterase inhibitor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| AD01 | Patent right deemed abandoned |
Effective date of abandoning: 20160203 |
|
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |