CN102641384B - Chinese patent medicine for treating pulpitis - Google Patents
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Abstract
The invention relates to a Chinese patent medicine for treating pulpitis, belonging to the technical field of medicaments for treating pulpitis. The Chinese patent medicine is prepared from dried rehmannia root, radix scrophulariae, gypsum, largetrifoliolious bugbane rhizome, manchurian wildginger, pagodatree flower, tree peony bark, cortex lycii radicis, baical skullcap root, Szechuan lovage rhizome, dahurian angelica root, fineleaf schizonepeta herb, divaricate saposhnikovia root, fortune's drynaria rhizome, tribulus terrestris, amur corktree bark, white chrysanthemum and liquoric root, andcan be prepared into various oral formulations according to a conventional pharmaceutical method. The Chinese patent medicine disclosed by the invention has the functions of tonifying qi, invigorating spleen, nourishing stomach, discharging fire, eliminating wind-fire, clearing and activating channels and collaterals, promoting blood circulation, removing blood stasis, strengthening vital qi, eliminating pathogen and regulating immunity and can achieve the purpose of treating pulpitis; and compared with the prior art, the Chinese patent medicine has the prominent substantive characteristics and significance of exact curative effect and convenience in administration.
Description
Technical field
The present invention relates to pulpitis treatment of diseases technical field, relate in particular to a kind of Chinese patent drug technique field for the treatment of the pulpitis disease.
Background technology
The pulpitis disease is commonly called as toothache, shows as violent insufferable pain, and the character of pain has following characteristics: spontaneous pain, the paroxysmal aggravation, be intermittent attack, under the situation of no extraneous any stimulation, suffer from odontogeny and have an intense pain, early stage pain duration of seizure is short, remission time is longer, and along with PD, late period, then the pain duration of seizure was long, remission time is shorter, and even does not have the catabasis at last; Night, pain was heavier than daytime, particularly put down when crouching more remarkable; Early stage hot and cold stimulation can cause that all pain increases the weight of, late period, cold stimulation did not only excite pain, make the pain respite on the contrary, so clinical common patient sucks cold water or inhales cold air to ease the pain, normal theory among the people " toothache is not disease; bitterly get up to want human life " just refers to the symptom of acute pulpitis late period (stadium suppurations); Moreover pain can not be located, the normal upper and lower jaw tooth and close on position radiation along the nervi trigeminus areal area to homonymy, and patient Chang Buneng points out the accurate position of cacodontia.
The pulpitis disease refers to that antibacterial or toxin invade the inflammation that the dental pulp be positioned at tooth center causes, most periapical pathological changes, particularly inflammation all are secondary to dental pulp disease.Acute pulpitis refers to the inflammation of acute pulp tissue, its source of infection is mainly from dark marrow, the infection of dental pulp can cause apical infection by apical foramen of tooth, clinical principal character is to have an intense pain, general analgesic drug product DeGrain, later stage can be developed into pulp gangrene, and many employings are at present removed the method treatment of dental pulp or opened marrow and medicine pain relieving, bring a lot of miseries to the patient.And various pulpitis disease all belongs to traditional Chinese medical science toothache category, and pathogenesis mainly contains wind-fire and violates tooth, wind and cold and violate tooth, stomach-fire and violate tooth, asthenic fire to violate tooth etc. former thereby cause.Therefore, seek a kind of illness new, that can eliminate the patient, have take medicine conveniently, curative effect is fast, the Chinese patent medicine of the treatment pulpitis disease that has no side effect is still the technical task that those skilled in the art need to be resolved hurrily.
Summary of the invention
Technical problem to be solved by this invention provides a kind of to eliminate patient's illness, promotion physical and mental health, the Chinese patent medicine that has the treatment pulpitis disease that the patient takes medicine conveniently, curative effect is fast, have no side effect simultaneously.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: a kind of Chinese patent medicine for the treatment of the pulpitis disease, its special character are to be made by the medicine of following weight proportioning: Radix Rehmanniae 30-45 part, Rhizoma Corydalis 30-45 part, Gypsum Fibrosum 30-45 part, Rhizoma Cimicifugae 5-15 part, Herba Asari 5-15 part, Flos Sophorae 15-30 part, Cortex Moutan 15-30 part, Cortex Lycii 15-30 part, Radix Scutellariae 15-30 part, Rhizoma Chuanxiong 10-25 part, Radix Angelicae Dahuricae 10-25 part, Herba Schizonepetae 15-30 part, Radix Saposhnikoviae 15-30 part, Rhizoma Drynariae 15-30 part, Fructus Tribuli 15-30 part, Cortex Phellodendri 15-30 part, Flos Chrysanthemi 15-30 part, Radix Glycyrrhizae 5-15 part.
For further solving the problems of the technologies described above, the Chinese patent medicine for the treatment of pulpitis disease of the present invention is to be made by the medicine of following preferred weight proportion: Radix Rehmanniae 35-40 part, Rhizoma Corydalis 35-40 part, Gypsum Fibrosum 35-40 part, Rhizoma Cimicifugae 8-12 part, Herba Asari 8-12 part, Flos Sophorae 20-25 part, Cortex Moutan 20-25 part, Cortex Lycii 20-25 part, Radix Scutellariae 20-25 part, Rhizoma Chuanxiong 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Schizonepetae 20-25 part, Radix Saposhnikoviae 20-25 part, Rhizoma Drynariae 20-25 part, Fructus Tribuli 20-25 part, Cortex Phellodendri 20-25 part, Flos Chrysanthemi 20-25 part, Radix Glycyrrhizae 8-12 part.
For further solving the problems of the technologies described above, the Chinese patent medicine for the treatment of pulpitis disease of the present invention is to be made by the medicine of the weight proportion of following the best: 38 parts in the Radix Rehmanniae, 38 parts of Rhizoma Corydalis, 38 parts of Gypsum Fibrosum, 10 parts of Rhizoma Cimicifugaes, 10 parts of Herba Asaris, 22 parts in Flos Sophorae, 22 parts of Cortex Moutans, 22 parts of Cortex Lycii, 22 parts of Radix Scutellariaes, 18 parts of Rhizoma Chuanxiongs, 18 parts of the Radixs Angelicae Dahuricae, 22 parts of Herba Schizonepetae, 22 parts of Radix Saposhnikoviaes, 22 parts of Rhizoma Drynariae, 22 parts of Fructus Tribulis, 22 parts of Cortex Phellodendris, 22 parts of Flos Chrysanthemis, 10 parts in Radix Glycyrrhizae.
The Chinese patent medicine for the treatment of pulpitis disease described above is characterized in that described Chinese patent medicine makes pill, sublimed preparation, powder, tablet, unguentum or decoction according to the conventional technology of preparing of Chinese medicine.
Chinese patent medicine described above also contains drug excipient.
Chinese patent medicine described above is the application as treatment pulpitis disease.
The principles of formulating prescriptions of Chinese patent medicine of the present invention are replenishing QI to invigorate the spleen, nourishing the stomach pathogenic fire purging, removing cold and wind, dredge the meridian passage, blood circulation promoting and blood stasis dispelling, set upright and get rid of evils, and regulate immunologic function, reach the purpose for the treatment of pulpitis disease.The present invention has proper, the reasonable recipe of compatibility of drugs, and the effect of its described each herbal medicine is:
The Radix Rehmanniae: sweet in the mouth, hardship, cold in nature.GUIXIN, liver, lung meridian.Function cures mainly: has the effect of clearing away heat and cooling blood, is used for curing mainly the warm febrile disease blood of joining the army, and the high fever coma, dry tongue is deep red; Control the epidemic febrile disease later stage, waste heat to the greatest extent, do not hinder, night fever abating at dawn, red tongue rapid pulse person by cloudy liquid; The warm febrile disease blood of joining the army, the heat in blood poison is contained, hematemesis and epistaxis, macule is purple black; YIN nourishing and the production of body fluid promoting, Tianjin wound are thirsty, and interior-heat is quenched one's thirst, and controls the epidemic febrile disease impairment of YIN, diseases such as dryness of the intestine constipation.
Rhizoma Corydalis: sweet in the mouth, salty, little hardship, cold in nature.Go into lung, stomach, kidney channel.Has the removing heat from blood YIN nourishing, eliminating fire and detoxication, fever excessive thirst, the effect of spontaneous sweating is used for mainly treating constipation, the haematemesis nose bleeding, pharyngolaryngitis, pulmonary tuberculosis, diseases such as constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin.
Gypsum Fibrosum: its acrid in the mouth, sweet, be slightly cold, attach to the lung and stomach meridians; Clearing away heat-fire is arranged, and relieving restlessness is quenched the thirst, the effect of convergence granulation promoting (using Gypsum Fibrosum Preparatum); It is oral administration both, also can external.Cure mainly the epidemic febrile disease intense heat in both QI and blood systems, hyperpyrexia is sent out speckle, heat clearing away speckle removing, dyspnea and cough due to lung-heat, restlessness and thirst; The high Sheng of stomach-fire, headache, toothache, gingival swelling and pain; Eczema, skin infection are not held back after bursting, and the various cases of a physically strong patient running a high fever such as burn due to hot liquid or fire reach the outer diseases such as skin ulcer, granulation promoting of holding back in order to heat clearing away.
Rhizoma Cimicifugae: sweet in the mouth, suffering, cool in nature; Has the yang invigorating of inducing sweat, the effect of heat-clearing and toxic substances removing; It is not smooth to be used for curing mainly saturating of measles, cold and heat, aphtha, laryngalgia, macule, skin infection, diseases such as chronic diarrhea proctoptosis and uterine prolapse.
Herba Asari: another name: bowl of a pipe flower, thin ginseng; Herb for the aristolochiaceae plant Herba Asari.Warm in nature, acrid in the mouth have and dispel the wind, cold expelling, row water, the effect of having one's ideas straightened out; Be used for curing mainly air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, diseases such as rheumatic arthralgia.
Flos Sophorae: remove impurity and ash bits.Cold nature, bitter in the mouth are returned liver, large intestine channel; Has cooling blood for hemostasis, the effect of purging liver-fire; Be used for curing mainly having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia is spitted blood, epistaxis, liver-heat conjunctival congestion, the dizzy disease of waiting of having a headache.
Cortex Moutan: property suffering, bitter in the mouth are slightly cold.Go into the heart, liver, kidney channel.Clinical practice. go into nutrient blood, hyperpyrexia, crimson tongue, body in epidemic febrile disease, heat and send out macule, bleeding due to blood-heat, haematemesis, epistaxis, hematuria have diseases such as antiinflammatory, anti-agglomeration.
Cortex Lycii: nature and flavor are sweet, light, and are cold in nature.Effect: clearing away heat and cooling blood.Cure mainly deficiency of YIN hectic fever due to YIN-deficiency, low grade fever does not move back; The lung-heat cough with asthma, expectorant blood night sweat; Bleeding due to blood-heat, diseases such as spitting of blood epistaxis.
Radix Scutellariae: another name Radix Scutellariae, tsuchikane tea root.For the labiate Radix Scutellariae, be used as medicine with root.Heat clearing and damp drying is arranged, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature, have the efficacy effect of promoting flow of QI and blood, wind-expelling pain-stopping, be used for the treatment of diseases such as menoxenia, amenorrhea dysmenorrhea, WEIJIA stomachache, costa sternales twinge, treating swelling and pain by traumatic injury, headache, rheumatic arthralgia.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature attaches to the lung and stomach meridians; Has expelling wind and cold, understand things pain-stopping, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, the effect of dampness leukorrhagia stopping; Be used for curing mainly diseases such as headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.The modern pharmacological research proof Radix Angelicae Dahuricae also has diseases such as antiinflammatory, antipyretic-antalgic.
Herba Schizonepetae: acrid in the mouth, slightly warm in nature, return lung, Liver Channel, have the effect of the diffusing wind that induces sweat, rash, the skin ulcer that disappears, hemostasis, be usually used in treatment flu, measles send out thoroughly smooth, have blood in stool, diseases such as metrorrhagia, epistaxis.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature, return bladder, liver, spleen channel, have the effect of expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion, be used for the treatment of diseases such as diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Rhizoma Drynariae: be rhizome such as Polypodiaceae plant Mongolian oak Herba pteridii latiusculi, drynaria baronii Diels, Semen Nelumbinis Rhizoma Zingiberis Recens Mongolian oak Herba pteridii latiusculi, precipice Rhizoma Zingiberis Recens, the close net Herba pteridii latiusculi of light and Davalliaceae plant Da Ye Rhizoma Drynariae, Rhizoma Drynariae.Bitter in the mouth, warm in nature, nontoxic.Go into liver, kidney channel.The effect of Rhizoma Drynariae: the kidney invigorating, invigorate blood circulation hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, diseases such as clavus.
Fructus Tribuli: another name, thatch, Fructus Tribuli, Fructus Tribuli, Fructus Atriplicis Sibiricae, society Fructus Tribuli soil Fructus Tribuli, Fructus Atriplicis Sibiricae, drought grass, triangle Fructus Tribuli, three JIAOCI, anistree thorn, puncture frame, wild Pedicellus et Pericarpium Trapae, Pedicellus et Pericarpium Trapae thorn etc.; Bitter in the mouth; Hot; Property is put down; Return liver, lung, kidney, heart channel; Effect: suppressing the hyperactive liver, resolving depression, dispelling pathogenic wind for improving eyesight; Cure mainly headache, dizzy, distending pain in the chest and hypochondrium, distending pain of the breast, breast and close diseases such as obstructed, amenorrhea, conjunctival congestion cataracta, rubella pruritus, vitiligo, skin ulcer cellulitis, scrofula.
Cortex Phellodendri: bitter in the mouth, cold in nature, have the effect of heat-clearing and toxic substances removing, heat clearing and damp drying, be used for curing mainly hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia; The hectic fever due to YIN-deficiency consumptive fever; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore; Diseases such as skin eczema.
Flos Chrysanthemi: Compositae, herbaceos perennial; Have another name called Flos Chrysanthemi, Flos Chrysanthemi, Flos Chrysanthemi, tea chrysanthemum, medicine chrysanthemum.Flos Chrysanthemi includes chrysanthemum glycoside, aminoacid, flavonoid and multivitamin and trace element, and Chinese medical studies show that, Flos Chrysanthemi has nourishing the liver to improve visual acuity, clears away heart-fire, the kidney invigorating, invigorating the spleen and regulating the stomach, wet one's whistle, promote the production of body fluid, and adjusts effect such as blood fat; Through the modern medicine checking, contain active chemical in the chrysanthemum, as adenine, choline, stachydrine etc., the volatile oil that extract from chrysanthemum contains Chrysanthemum ketone, Borneolum Syntheticum, borneol acetate etc.Pharmacological evaluation proves that the Flos Chrysanthemi decoct has inhibitory action to Song Shi dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, escherichia coli and vibrio cholera etc.
Radix Glycyrrhizae: sweet in the mouth, property are put down; Has heat-clearing and toxic substances removing, nourishing the lung to arrest cough, the effect of coordinating the actions of various ingredients in a prescription, invigorating the spleen and replenishing QI; Be used for curing mainly laryngopharynx swelling and pain, cough, weakness of the spleen and stomach, stomach, duodenal ulcer, hepatitis, hysteria, carbuncle furuncle and phyma poison, diseases such as medicine and alimentary toxicosis.
Chinese patent medicine of the present invention is followed the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", and all composition comes from the 5th edition medicine that records of China's " pharmacopeia ", and all medicines have temperature compensation liver spleen mutually and altogether, the wind that looses dehumidifies, QI and blood regulating, is set upright and is got rid of evils dredge the meridian passage, blood circulation promoting and blood stasis dispelling, regulates immunologic function, improve skin microcirculation, promote dispelling cold by warming the meridian, the effect of the blood stasis dispelling of nourishing blood, treatment and the sick determined curative effect of prevention pulpitis, have no side effect various Chinese medicine preparation taking conveniences.
The clinical use result of Chinese patent medicine of the present invention shows to have following advantage:
1, the Chinese patent medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes comprehensive function treatment and the prevention pulpitis disease of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Acute toxicity test and accumulation toxicity test through white mice and rat show that underproof animal does not see any toxic reaction, compare zero difference through anatomic observation hemogram, liver function, each organs and tissues morphology finding and matched group, prove that its safety of medicine is reliable.
2, Chinese patent medicine preparation of the present invention need not decoct, not have bitterness sense, rich in proteins, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid in the medicine, also contain various trace elements such as Saponin, plant sterol, calcium, be conducive to absorption of human body, health invigorating, and taking convenience.
3, Chinese patent medicine preparation of the present invention not only can effectively be treated the pulpitis disease, and it is also very obvious to the preventive effect of pulpitis disease, particularly by working in coordination with mutually between the medicine, strengthen medicine and treat characteristic separately, by dredge the meridian passage and adjusting immunologic function, improve healthy energy and the physical and mental health of patient body inherence, reached the healing rehabilitation efficacy preferably.
Further specify Chinese patent medicine of the present invention to the therapeutic effect for the treatment of pulpitis disease below by clinical practice.
One, clinical diagnosis standard:
1. the cause of disease of pulpitis:
Pulpitis is commonly called as toothache, shows as violent insufferable pain, and the character of pain has following characteristics: spontaneous pain, the paroxysmal aggravation, be intermittent attack, under the situation of no extraneous any stimulation, suffer from odontogeny and have an intense pain, early stage pain duration of seizure is short, remission time is longer, and along with PD, late period, then the pain duration of seizure was long, remission time is shorter, and even does not have the catabasis at last; Night, pain was heavier than daytime, particularly put down when crouching more remarkable; Early stage hot and cold stimulation can cause that all pain increases the weight of, and late period, cold stimulation did not only excite pain, made the pain respite on the contrary, so clinical common patient sucks cold water or inhales cold air to ease the pain, the symptom of acute pulpitis late period (stadium suppurations) that Here it is; Moreover pain can not be located, the normal upper and lower jaw tooth and close on position radiation along the nervi trigeminus areal area to homonymy, and patient Chang Buneng points out the accurate position of cacodontia.The reason that causes pulpitis has antibacterial factor, physical factor, chemical factor and the special sexual factor of sending out to have:
(1) antibacterial factor: pulpitis can be described as a kind of infectious disease, and antibacterial is the important paathogenic factor of dental pulp disease.Cause that the approach that dental pulp infects has through the infection of tooth body, periodontal infection and three aspects of infection, blood source.Accidental pulp exposure when dental caries, traumatic odontagma and brill are ground one's teeth in sleep body, wedge shaped defect reveal marrow, old people seriously wear away reveal marrow, but central cusp deformity fractures or the bottom of revealing marrow, invaginated lingual fossa or lopsided lingual developmental groove of wearing and tearing equal dental pulp of exposing of direct infection of antibacterial when not having enamel and covering, when odentoschim reaches pulp cavity deeply, as the dentin that is covered in the pulp tissue is very thin, and antibacterial and toxic product thereof can pass dentinal tubule and arrive pulp cavity and cause that dental pulp infects; Antibacterial also can enter pulp cavity by apical foramen of tooth and cause retrograde infection by periodontal pocket to the tip of a root by periodontal tissue, thisly is called ascending pulpitis via the caused pulpitis of periodontal infection dental pulp.
(2) physical factor: acute tooth wound, have a fist fight to make tooth to chew hard thing suddenly in being clashed or taking food as vehicle accident, agonistic sports, violence, and the accident in the curative activity, as carry out overexerting when denture is rescued, mobile tooth is too fast, accidentally injure adjacent teeth root week during exodontia, scrape the mechanical injury that damage tip of a root blood vessel when controlling dark periodontal pocket etc. causes, the chronic mechanical injury such as tramatic occlusion of stinging that traumatogenic articulation, charges or other dummies be too high to be caused.
(3) chemical factor: absorption, the outer absorption of tooth can cause some agnogenic dental pulp pathological changes in the tooth.
2. the classification of pulpitis:
Pulpitis is divided into the recoverability pulpitis, does not absorb five big classes in the recoverability pulpitis, pulp necrosis, pulp calcification, tooth, and wherein modal is exactly preceding two kinds: recoverability pulpitis and recoverability pulpitis not.
(1) recoverability pulpitis: the pulpitis that a kind of pathological changes is lighter is equivalent to " pulp hyperemia ".When dental pulp is subjected to thermal stimulus, produce of short duration, sharp-pointed pain, after stimulating removal, pain disappears immediately.During clinical examination, remove the bad tissue of most dental caries, no perforation of pulp chamber hole; The dental pulp electroprobe checks, reacts identical with normal teeth or high slightly, and the cold stimulation test produces pain, stimulates a removal pain to disappear immediately.Its main feature is: no spontaneous pain history, after stimulation was removed, pain disappeared immediately.The principle for the treatment of recoverability pulpitis: removing stimulates, and diminishes inflammation.
(2) recoverability pulpitis not: comprise acute, chronic, ascending pulpitis, be difficult to clinically be distinguished from scope and the character of inflammatory disorders, eliminate pathological changes and all need remove dental pulp in the treatment, but its clinical characters is different.
1. acute pulpitis: can be the chronic pulpitis acute attack by the development of recoverability pulpitis.Its clinical characters is anxious for morbidity, sharp ache.Show as spontaneous pain, paroxysmal outbreak or severe pain, how diffusing property can not oneself determine the tooth position, and night, pain was violent than daytime, thermal stimulus can cause or aggravate the pain, stimulate to remove back pain and continue for some time, it is violent also may to suffer from the pain of having a toothache, and is impatient at body temperature and meets cold water pain relief (suppurative pulpitis), can find dark cavity or other dental hard tissue's illness, suffering from tooth can have the tapping pain.
2. chronic pulpitis: mostly be due to the dental caries, do not have violent spontaneous pain, slight dull pain is arranged sometimes, the caloric stimulation pain history that long period is arranged, want long period pain just can fade away after removing stimulation, how can locate voluntarily, suffering from tooth can have slight interlock pain or kowtow pain; Can find dark cavity or other dental hard tissue's illness, responsive dew pith cavity (ulcerating pulpitis) can be arranged, or do not have dew pith cavity (closed pulpitis), or at dew pith cavity place outstanding pulp polyp (hyperplastic pulpitis) be arranged; Reactions vary for temperature test, many to thermo-responsive or slowness reaction pain arranged.
3. ascending pulpitis: be after the periodontal tissue of periodontal sufferer tooth destroys, to infect entering the dental pulp inflammation that dental pulp causes by side, secondary root pipe or apical foramen of tooth.Suffer from tooth with serious periodontal disease, show the multifrequency nature of periodontitis, periapical periodontitis and pulpitis simultaneously.Spontaneity and paroxysmal pain are arranged, to the hot and cold performance that stimulates sensitivity or acute pulpitiss such as referred pain are arranged; Also can show as tooth dull pain, distending pain, not have obvious spontaneous pain, to the symptom of chronic pulpitiss such as hot and cold stimulation sensitivity; Check visible dark periodontal pocket, or traumatogenic articulation, odontoseisis, kowtow pain; X-ray film shows the periapical frontal resorption.
Be not difficult to diagnose according to clinical manifestation, need differentiate with following disease:
1, differentiate with dark dental caries: they have darker cavity, but the spontaneity that dark dental caries do not have acute pulpitis has an intense pain.
2, differentiate with papillary gingivitis: papillary gingivitis can have spontaneity to have an intense pain, but local red swelling of gingiva, tenderness, even pyorrhea, and the food impaction history is arranged more.Pulpitis does not then have, and pulpitis is to responsive to temperature, and papillary gingivitis does not then have significant reaction to the stimulation of temperature.
Pulpitis
3, differentiate with trigeminal neuralgia: trigeminal neuralgia does not generally show effect at night, and temperature change does not also cause pain, and " trigger point " arranged more, and the pain intermission can obviously not prolong with PD or shorten.
Auxiliary examination: the X line is taken the photograph sheet or oral cavity body cavity and is photographed to understand and have or not the acute pulpitis performance.
Two, case selection:
The sickness rate of pulpitis disease is relevant with the dietary habit of ethnic group with the area, and generally the middle-aged and elderly people sickness rate is more high, and M-F is roughly suitable, puts down in writing according to interrelated data: age of onset is in the majority more than 30 years old, asthenic fire, flaming up of stomach-fire and cause.For this reason, case selection is whole cases with door rash prescription on individual diagnosis patient.
Three, curative effect discrimination standard:
The curative effect discrimination standard that does not still have at present treatment by Chinese herbs pulpitis disease, the reference standard that classification is drafted according to the clinical treatment result are as this standard:
1. recovery from illness: the clinical symptoms complete obiteration, treat back not recurrence more than 2 years;
2. produce effects: clinical symptoms disappears substantially, treats back recurrence more than 1 year;
3. take a turn for the better: clinical symptoms disappears substantially, stops to treat 1 year with interior slight recurrence, but does treatment and recovery voluntarily;
4. invalid: clinical symptoms is intermittently outbreak during treating, and stops to treat still repeatedly recurrence in half a year, must go treatment again.
Four, clinical application method and therapeutic outcome:
1, clinical application method:
According to patient's sick time, the cause of disease, scope and distribution situation, the component medication; Take the oral medicine preparation of the described Chinese patent medicine of the embodiment of the invention, each 6-9 gram, every day 3 times, warm water delivery service, take half an hour ante cibum.One month is a course for the treatment of, take continuously one the course for the treatment of observe the curative effect.
2, therapeutic outcome
The patient amounts to 76 examples through clinical diagnosis treatment pulpitis, male's 42 examples, and women's 34 examples, the age is 59 examples more than 40 years old, having only 16 examples is below 40 years old.Recovery from illness 53 examples account for 69.74% among the 76 routine patients, and produce effects 16 examples account for 21.05%, and effective 5 examples account for 6.58%, and invalid 2 examples account for 2.63%, and total effective rate reaches 97.37%.After treatment, patient's pulpitis disease recovery from illness in various degree, and patient do not have any untoward reaction, three big routine tests and hepatic and renal function detect do not find any unusually.
The specific embodiment
Embodiment 1
Press the row weight portion and take by weighing each Chinese crude drug: Radix Rehmanniae 30-45 part, Rhizoma Corydalis 30-45 part, Gypsum Fibrosum 30-45 part, Rhizoma Cimicifugae 5-15 part, Herba Asari 5-15 part, Flos Sophorae 15-30 part, Cortex Moutan 15-30 part, Cortex Lycii 15-30 part, Radix Scutellariae 15-30 part, Rhizoma Chuanxiong 10-25 part, Radix Angelicae Dahuricae 10-25 part, Herba Schizonepetae 15-30 part, Radix Saposhnikoviae 15-30 part, Rhizoma Drynariae 15-30 part, Fructus Tribuli 15-30 part, Cortex Phellodendri 15-30 part, Flos Chrysanthemi 15-30 part, Radix Glycyrrhizae 5-15 part.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made sublimed preparation according to the pharmaceutical methods that routine prepares sublimed preparation, and its described Chinese patent medicine is the application as treatment pulpitis disease.
Embodiment 2
Press the row weight portion and take by weighing each medical material: Radix Rehmanniae 30-45 part, Rhizoma Corydalis 30-45 part, Gypsum Fibrosum 30-45 part, Rhizoma Cimicifugae 5-15 part, Herba Asari 5-15 part, Flos Sophorae 15-30 part, Cortex Moutan 15-30 part, Cortex Lycii 15-30 part, Radix Scutellariae 15-30 part, Rhizoma Chuanxiong 10-25 part, Radix Angelicae Dahuricae 10-25 part, Herba Schizonepetae 15-30 part, Radix Saposhnikoviae 15-30 part, Rhizoma Drynariae 15-30 part, Fructus Tribuli 15-30 part, Cortex Phellodendri 15-30 part, Flos Chrysanthemi 15-30 part, Radix Glycyrrhizae 5-15 part.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made packed powder according to the pharmaceutical methods that routine prepares powder, and its described Chinese patent medicine is the application as treatment pulpitis disease.
Embodiment 3
Press the row weight portion and take by weighing each medical material: Radix Rehmanniae 35-40 part, Rhizoma Corydalis 35-40 part, Gypsum Fibrosum 35-40 part, Rhizoma Cimicifugae 8-12 part, Herba Asari 8-12 part, Flos Sophorae 20-25 part, Cortex Moutan 20-25 part, Cortex Lycii 20-25 part, Radix Scutellariae 20-25 part, Rhizoma Chuanxiong 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Schizonepetae 20-25 part, Radix Saposhnikoviae 20-25 part, Rhizoma Drynariae 20-25 part, Fructus Tribuli 20-25 part, Cortex Phellodendri 20-25 part, Flos Chrysanthemi 20-25 part, Radix Glycyrrhizae 8-12 part.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made unguentum according to the pharmaceutical methods that routine prepares unguentum, and its described Chinese patent medicine is the application as treatment pulpitis disease.
Embodiment 4
Press the row weight portion and take by weighing each medical material: Radix Rehmanniae 35-40 part, Rhizoma Corydalis 35-40 part, Gypsum Fibrosum 35-40 part, Rhizoma Cimicifugae 8-12 part, Herba Asari 8-12 part, Flos Sophorae 20-25 part, Cortex Moutan 20-25 part, Cortex Lycii 20-25 part, Radix Scutellariae 20-25 part, Rhizoma Chuanxiong 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Schizonepetae 20-25 part, Radix Saposhnikoviae 20-25 part, Rhizoma Drynariae 20-25 part, Fructus Tribuli 20-25 part, Cortex Phellodendri 20-25 part, Flos Chrysanthemi 20-25 part, Radix Glycyrrhizae 8-12 part.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made tablet according to the pharmaceutical methods that routine prepares tablet, (as conventional tablet, sugar coated tablet, film coated tablet etc.), and give conventional drug excipient (as starch, sucrose, lactose, calcium stearate, magnesium stearate etc.), its described Chinese patent medicine is the application as treatment pulpitis disease.
Embodiment 5
Press the row weight portion and take by weighing each medical material: 38 parts in the Radix Rehmanniae, 38 parts of Rhizoma Corydalis, 38 parts of Gypsum Fibrosum, 10 parts of Rhizoma Cimicifugaes, 10 parts of Herba Asaris, 22 parts in Flos Sophorae, 22 parts of Cortex Moutans, 22 parts of Cortex Lycii, 22 parts of Radix Scutellariaes, 18 parts of Rhizoma Chuanxiongs, 18 parts of the Radixs Angelicae Dahuricae, 22 parts of Herba Schizonepetae, 22 parts of Radix Saposhnikoviaes, 22 parts of Rhizoma Drynariae, 22 parts of Fructus Tribulis, 22 parts of Cortex Phellodendris, 22 parts of Flos Chrysanthemis, 10 parts in Radix Glycyrrhizae.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made pill according to the pharmaceutical methods that routine prepares pill, and give conventional drug excipient, its described Chinese patent medicine is the application as treatment pulpitis disease.
Embodiment 6
Press the row weight portion and take by weighing each medical material: 38 parts in the Radix Rehmanniae, 38 parts of Rhizoma Corydalis, 38 parts of Gypsum Fibrosum, 10 parts of Rhizoma Cimicifugaes, 10 parts of Herba Asaris, 22 parts in Flos Sophorae, 22 parts of Cortex Moutans, 22 parts of Cortex Lycii, 22 parts of Radix Scutellariaes, 18 parts of Rhizoma Chuanxiongs, 18 parts of the Radixs Angelicae Dahuricae, 22 parts of Herba Schizonepetae, 22 parts of Radix Saposhnikoviaes, 22 parts of Rhizoma Drynariae, 22 parts of Fructus Tribulis, 22 parts of Cortex Phellodendris, 22 parts of Flos Chrysanthemis, 10 parts in Radix Glycyrrhizae.
The preparation technology of present embodiment is: above-mentioned each medicinal raw material is made oral solutions according to the pharmaceutical methods that routine prepares oral solutions, and its described Chinese patent medicine is the application as treatment pulpitis disease.
Claims (5)
1. a Chinese patent medicine for the treatment of the pulpitis disease is characterized in that being made by the medicine of following weight proportioning: Radix Rehmanniae 30-45 part, Rhizoma Corydalis 30-45 part, Gypsum Fibrosum 30-45 part, Rhizoma Cimicifugae 5-15 part, Herba Asari 5-15 part, Flos Sophorae 15-30 part, Cortex Moutan 15-30 part, Cortex Lycii 15-30 part, Radix Scutellariae 15-30 part, Rhizoma Chuanxiong 10-25 part, Radix Angelicae Dahuricae 10-25 part, Herba Schizonepetae 15-30 part, Radix Saposhnikoviae 15-30 part, Rhizoma Drynariae 15-30 part, Fructus Tribuli 15-30 part, Cortex Phellodendri 15-30 part, Flos Chrysanthemi 15-30 part, Radix Glycyrrhizae 5-15 part.
2. the Chinese patent medicine for the treatment of pulpitis disease according to claim 1 is characterized in that being made by the medicine of following weight proportioning; Radix Rehmanniae 35-40 part, Rhizoma Corydalis 35-40 part, Gypsum Fibrosum 35-40 part, Rhizoma Cimicifugae 8-12 part, Herba Asari 8-12 part, Flos Sophorae 20-25 part, Cortex Moutan 20-25 part, Cortex Lycii 20-25 part, Radix Scutellariae 20-25 part, Rhizoma Chuanxiong 15-20 part, Radix Angelicae Dahuricae 15-20 part, Herba Schizonepetae 20-25 part, Radix Saposhnikoviae 20-25 part, Rhizoma Drynariae 20-25 part, Fructus Tribuli 20-25 part, Cortex Phellodendri 20-25 part, Flos Chrysanthemi 20-25 part, Radix Glycyrrhizae 8-12 part.
3. the Chinese patent medicine for the treatment of pulpitis disease according to claim 1 is characterized in that being made by the medicine of following weight proportioning: 38 parts in the Radix Rehmanniae, 38 parts of Rhizoma Corydalis, 38 parts of Gypsum Fibrosum, 10 parts of Rhizoma Cimicifugaes, 10 parts of Herba Asaris, 22 parts in Flos Sophorae, 22 parts of Cortex Moutans, 22 parts of Cortex Lycii, 22 parts of Radix Scutellariaes, 18 parts of Rhizoma Chuanxiongs, 18 parts of the Radixs Angelicae Dahuricae, 22 parts of Herba Schizonepetae, 22 parts of Radix Saposhnikoviaes, 22 parts of Rhizoma Drynariae, 22 parts of Fructus Tribulis, 22 parts of Cortex Phellodendris, 22 parts of Flos Chrysanthemis, 10 parts in Radix Glycyrrhizae.
4. according to the Chinese patent medicine of the described treatment pulpitis of arbitrary claim disease in the claim 1 to 3, it is characterized in that described Chinese patent medicine makes pill, sublimed preparation, powder, tablet, unguentum or decoction according to the conventional technology of preparing of Chinese medicine.
5. the Chinese patent medicine for the treatment of pulpitis disease according to claim 4 is characterized in that described Chinese patent medicine also contains drug excipient.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105232773A (en) * | 2015-10-24 | 2016-01-13 | 四川双鑫生物科技有限公司 | Decoction medicine treating pulpitides and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103830644A (en) * | 2014-02-17 | 2014-06-04 | 刘禾青 | Traditional Chinese medicine composition for treatment of pulpitis |
| CN103919915A (en) * | 2014-04-28 | 2014-07-16 | 四川金堂海纳生物医药技术研究所 | Oral medicine for treating apicitis and preparation method thereof |
| CN104435345A (en) * | 2014-11-11 | 2015-03-25 | 四川金堂海纳生物医药技术研究所 | Orally taken medicine for treating pulpitis and preparation method thereof |
| CN105055653A (en) * | 2015-08-14 | 2015-11-18 | 成都市飞龙水处理技术研究所 | Medicine decoction for treating pulpitis and preparation method thereof |
| CN105055645A (en) * | 2015-08-19 | 2015-11-18 | 陈晓 | Traditional Chinese medicine preparation for treating pulpitis and preparation method thereof |
| CN108261471A (en) * | 2016-12-30 | 2018-07-10 | 王洪英 | A kind of Chinese drugs agentia and preparation method for treating dental pain |
| CN106491971A (en) * | 2017-01-03 | 2017-03-15 | 陈玉琴 | A kind of for treating Chinese medicine composition of pulpitiss and preparation method thereof |
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| CN101095747A (en) * | 2007-07-12 | 2008-01-02 | 尹克华 | Chinese traditional medicine for treating various toothache |
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| CN105232773A (en) * | 2015-10-24 | 2016-01-13 | 四川双鑫生物科技有限公司 | Decoction medicine treating pulpitides and preparation method thereof |
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