CN102641230A - Traditional Chinese medicine nine-kernel skin nourishing cream and preparation method thereof - Google Patents
Traditional Chinese medicine nine-kernel skin nourishing cream and preparation method thereof Download PDFInfo
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Abstract
The utility model discloses a traditional Chinese medicine nine-kernel skin nourishing cream and a preparation method thereof. According to a formula, the traditional Chinese medicine nine-kernel skin nourishing cream contains the following components in parts by weight: 3-10 parts of apricot kernel, 9-30 parts of adlay kernel, 9-15 parts of cannabis kernel, 4.5-9 parts of peach kernel, 9-15 parts of date kernel, 3-6 parts of fructus amomi, 1-5 parts of ricinus communis kernel, 15-30 parts of sesame kernel and 3-6 parts of olive kernel. The preparation method comprises extraction of a traditional Chinese medicine active ingredients, decoloration and preparation of cream and specifically comprises the following steps: carrying out supercritical extraction on the traditional Chinese medicines by carbon dioxide to obtain a traditional Chinese medicine extract for standby use, then extracting supercritically-extracted traditional Chinese medicine dregs by carbonic ester, and carrying out vacuum concentration on carbonic ester extraction solution to obtain carbonic ester extracted traditional Chinese medicine coarse cream; and at last, carrying out reflux and water extraction on the traditional Chinese medicine dregs, carrying out vacuum condensation on the water extracted traditional Chinese medicine to obtain water extracted traditional Chinese medicine coarse cream; dissolving the traditional Chinese medicine extract and the traditional Chinese medicine coarse cream in ethanol water solution with ethanol concentration being 45-80 percent, adding activated carbon for decoloration, carrying out filtering and condensation to obtain traditional Chinese medicine pure cream, mixing the traditional Chinese medicine extract and the traditional Chinese medicine pure cream with a cream agent, and then preparing the Chinese medicine nine-kernel skin nourishing cream by a traditional method.
Description
Technical field
The invention belongs to the daily-use chemical industry technical field, relate to a kind of Chinese medicine nine core cream of nourishing face and preparation method thereof.
Background technology
Various types of pigments of application on human skin mainly are because the human endocrine imbalance causes free oxygen free radical activation in the body, and tyrosinase activity is increased, the pigment anomaly deposition, thus cause chloasma, freckle, senile plaque etc.Will stop these mottles to form artificially, have only free oxygen free radical in the cortex of removing and the body, the restraint of tyrosinase activity just can achieve the goal.Chinese medicine thinks that melanic formation is owing to due to the reasons such as QI and blood retardance, depression of liver-QI, deficiency of kidney yin, impairment caused by overstrain spleen soil unusually; Can adopt Chinese medicine with the effect of enriching blood, invigorate blood circulation and regulate the flow of vital energy, through nourish blood, invigorate blood circulation, soothing liver-QI for relieving depression reduces melanic formation and nurses one's health.Invigorate blood circulation with Chinese medicine, make mechanism of qi be able to smoothness, promote local blood circulation, improve the local skin metabolism, pigment is dribbled.
Along with raising, the raw material of technology level are enriched constantly, increasing external raw material and the technology of having adopted of present cosmetics makes that the function of cosmetics is more and more stronger, prepares more and more superior.The cosmetics of white-skinned face function are a lot of in the market; Traditional skin-whitening agents; With hydrogen peroxide, hydrogen chloride base hydrargyrum and various phenol derivatives, these chemical compounds can make existing or surperficial melanin organize rapidly to disintegrate, reach the effect of whitening fast toward contact.But can not effectively suppress melanin regrows because its composition of whitening does not infiltrate through the skin internal layer; Mottle can occur again after a period of time, can not be from basic solution because the human endocrine imbalance causes free oxygen free radical activation in the body; Make tyrosinase activity increase the abnormal deposition of pigment.
The Along with people's growth in the living standard, the modern also requires increasingly high for the pursuit of U.S.A, and the effect that the body whitening cr Pear Power is preserved moisture is requisite a kind of skin care item during people live.Modern medicine study show Chinese medicine can through improve unusual hemorheology, suppress cheese hydracid enzymatic activity and melanocytic propagation is synthetic, improve body superoxide dismutase (SOD) active with remove the effect that unnecessary superoxide radical reaches whitening and speckle dispelling.Therefore, has theoretical foundation with the Chinese medicine whitening and moistening skin.The psychology of pursuing green cosmetics, back to nature people strengthens day by day, and the natural activity cosmetics are complied with the trend that goes back to nature and people's consumer psychology.
200710177764.8 1 kinds of incense cure emollient creams of China application number CN and preparation method thereof.It cooperates excipient paraffin 30-60 part, glycerol 30-60 part mix homogeneously to form mainly by Olibanum quintessence oil 1-5 part, Benzoinum quintessence oil 1-5 part, orange blossom quintessence oil 2-10 part, tea tree oil 5-20 part, the essential oil 1-5 part of returning from the grave.This emollient cream ability rapid permeability to skin internal layer promotes the absorption of nutritional labeling, promotes skin metabolism, makes skin recover elasticity and vigor; Tighten skin pore simultaneously, make skin careful, smooth; Can effectively prevent the generation of mottle and wrinkle, have moistening effect and strengthen the preserve moisture water holding capacity of layer of skin, make skin lubricated and be rich in gloss.
China application number CN 200910101139.4 is manufacture methods of a kind of anti-aging moisturizer.Manufacture method is to take by weighing Rhizoma Atractylodis Macrocephalae 5-part by weight, Poria 5-10 part, and Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10 part, Radix Angelicae Dahuricae 5-10 part, Radix Ampelopsis 5-10 part is pulverized, and mix homogeneously gets mixture A; In the ratio of mixture A and water weight ratio 1: 3-5 mixture A is dropped in the water and to decoct 1-3 hour, filter, filtering residue repeats to decoct once again, filters, merge 2 times filtrate liquor B; With the liquor B reverse osmosis concentration, get concentrated solution C again; Take by weighing distilled water 10-20 part then by weight, add glycerol 3-8 part, tea polyphenols 1-3 part, vitamin A 1-2 part, SOD 0.3-0.7 part, the kojic acid palm fibre is put acid esters 0.5-2 part, and heating for dissolving gets mixture D; The last vaseline that takes by weighing 20-50 part by weight after heating is dissolved, adds concentrated solution C and mixture D, stirs, and cooling promptly gets product.This invention contains SOD, tea polyphenols, the stronger composition of this type of Rhizoma Atractylodis Macrocephalae removing free radical, through removing the free radical in the tissue, keeps the integrity of cell function, thereby reaches the purpose of opposing senility of humanbody, not only can take stopgap measures but also can effect a permanent cure.The kojic acid palm fibre put acid esters, Poria, poliosis, in vain just, the Radix Ampelopsis composition, have good white-skinned face function, vitamin A can also well smooth away wrinkles, mottle, glycerol and vaseline can also stop the loss of moisture, keep skin wet.Therefore be a Pear Power, speckle dispelling, reduce wrinkle, preserve moisture, emollient cream of anti-senescence function.
China application number CN 201010522529.1 is a kind of medicine skin skin whiteners and preparation method thereof.This frost with dog oil, Adeps Caprae seu ovis, in vain just, Radix Glycyrrhizae, the Rhizoma Pinelliae, Fructus Mume, Herba Spirodelae, Fructus Gleditsiae Abnormalis be raw material; With the dog oil in the component, Adeps Caprae seu ovis at pot internal heating to 40 ℃; Again will be in vain just, Radix Glycyrrhizae, the Rhizoma Pinelliae, Fructus Mume, Herba Spirodelae, Fructus Gleditsiae Abnormalis add in the pot; Continue to be heated to boiling, slow fire boiled 40-50 minute again, promptly got through carrying out packing after elimination slag, the cooling.
At present; Cosmetics on the market are of a great variety; Like cosmetic cream, beauty cream, fair complexion cream, the cleansing milk or the like of whitening, its prescription contains all generally that animal oil, octadecanol, glycerol, nipalgin second are cured, silicone oil, monoglyceride, water etc., and this type beauty treatmentization is herded the production technology of article and filled a prescription all is similar basically; Also in various degree human body skin is had the effect of protection beauty treatment, but effect is not fine.Traditional emollient cream, freckle effect is relatively poor, and effective ingredient contains synthetics, and zest is bigger, and abnormal smells from the patient is relatively poor.Existing overcome above-mentioned shortcoming medicine emollient cream since its extracts active ingredients use steam distillation, there are a lot of drawbacks in this preparation technology, its extraction ratio is low; Can not the composition of some high boiling point and low volatility all be extracted; And be in for a long time under the condition of high temperature, the easy loss of the volatile ingredient of medicine, some is prone to pyrolytic material or the chemical instability composition also is prone to be destroyed; The loss of effective components of medicine is huge, has had a strong impact on the effect curative effect of medicine.Therefore, traditional water boiling and extraction also is at high temperature to carry out, and the part effective ingredient of medical material is destroyed because of being heated for a long time, and extraction ratio is low, and the curative effect of medicine is also had very big influence.Cream of nourishing face of the present invention is a kind of of emulsion, can deeply moisten dry skin, replenishes the moisture content nutrition of skin loss every day, reaches the effect of speckle dispelling, skin care.
Summary of the invention
The objective of the invention is: the one, adopt the pure natural medical material to process, abnormal smells from the patient delicate fragrance, and non-stimulated; Do not have irritated reaction, make medicine ability rapid permeability to skin internal layer, promote the absorption of nutritional labeling; Promote skin metabolism; Remove free oxygen free radical in cortex and the body, restraint of tyrosinase is active, makes skin recover elasticity and vigor; The 2nd, its extraction ratio that overcomes the prior preparation method existence is low; Can not the composition of some high boiling point medicine all be extracted; The easy loss of volatile ingredient of low volatility medicine, the deficiency that the loss of effective components of medical material is big and a kind of Chinese medicine nine core cream of nourishing face and preparation method thereof are provided.
Technical scheme of the present invention is:
The present invention is the basis according to first inventor's secret recipe handed down in the family; Think that in conjunction with Chinese medicine melanic formation is owing to due to the reasons such as QI and blood retardance, depression of liver-QI, deficiency of kidney yin, impairment caused by overstrain spleen soil unusually; Can adopt Chinese medicine with the effect of invigorating blood circulation and regulate the flow of vital energy, through nourish blood, invigorate blood circulation, soothing liver-QI for relieving depression reduces the principle that melanic formation is nursed one's health.Invigorate blood circulation with Chinese medicine, make mechanism of qi be able to smoothness, promote local blood circulation, improve the local skin metabolism, pigment is dribbled.Selecting for use can heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation, and removing heat from blood nourishes blood, astringing to arrest bleeding; Detumescence and promoting granulation is removed free radical, can improve microcirculation in human body, promotes skin metabolism; Eliminate nine kinds of pit core of Chinese medicine class medical material that pigment is excessively piled up in tissue, adopt supercritical extraction, carbonic ester extraction and water extracting method, pharmaceutically active ingredient in the extraction; Preparation can be goed deep into the skin internal layer through Transdermal absorption, promotes the absorption of nutritional labeling, endocrine regulation balance for oral administration; Get rid of metabolic waste and free oxygen free radical, suppress tyrosine bacterium activity, promote skin metabolism, effectively prevent the generation of mottle and wrinkle; Make skin recover elasticity and vigor, have moistening effect and strengthen the preserve moisture water holding capacity of layer of skin, make skin lubricated and be rich in glossy Chinese medicine nine core cream of nourishing face.
The Chinese medicine pharmacology that the present invention adopts:
1, Semen Armeniacae Amarum: Semen Armeniacae Amarum (Amygdalus Communis Vas), another name: almond core, Fructus Pruni, wood are begun, Semen Armeniacae Amarum, Prunus mume var.bungo Makino core, Fructus Pruni, sweet prunus mume (sieb.) sieb.et zucc..Bitter in the mouth, warm in nature, poisonous, return lung, spleen, large intestine channel.Have expelling phlegm for arresting cough, relieving asthma, intestine moistening, following air to open numbness effect.Modern medicine research proof, contained fatty oil can make keratodermatitis softening in the Semen Armeniacae Amarum, moisturizes skin protection, and the effect of neuroprotective peripheral vessel and histoorgan is arranged, and can press down and kill antibacterial.In addition, can be suppressed intravital active tryrosinase, eliminate pigmentation, freckle, black speck etc., thereby reach the effect of beauty treatment by the HCN that enzyme hydrolysis generated.
2, Semen Coicis: Semen Coicis (Semen Coicis), another name: Semen Coicis, Semen Coicis, Semen Coicis, native corn, Semen Coicis, a reality, heart of a lotus seed pearl, careless pearl pearl, jobstears, Semen Coicis, NLIUGU.Sweet in the mouth, light, cool in nature, return spleen, stomach, large intestine channel.Has the dampness removing spleen invigorating; Arthralgia relieving by relaxing muscles and tendons; The clearing away heat and discharging pus effect.Be used for edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.All on the books in China's medical book ancient books, Semen Coicis is splendid beauty treatment food materials, has looks improving and the skin nourishing effects such as the flat pox of the wart of controlling, light speckles, beautification and white, skin moistening reduce wrinkle, and especially contained proteolytic enzyme can make skin keratin softening, the vitamin E Wheat Protein.
3, Fructus Cannabis: Fructus Cannabis (Cannabis sativa L.), another name: cannabis,fructus, Urtica cannabina L., hemp.Sweet in the mouth, property is flat, returns spleen, stomach, large intestine channel.Have and moisturize, laxation, treating stranguria, the effect of invigorating blood circulation.Be used for the dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, dysentery.Menoxenia, scabies, tinea leprosy.
4, Semen Persicae: Semen Persicae (semenpersicae peachseed), another name: Radix Fici Hirtae core, big Semen Persicae.Bitter in the mouth, sweet, property is flat, GUIXIN, liver, large intestine channel warp.Has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, cough and asthma relieving efficacy.Be used for amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
5, Semen Ziziphi Spinosae: Semen Ziziphi Spinosae (Semen Ziziphi Spinosae), another name: Semen Ziziphi Spinosae.Sour in the mouth is sweet, and property is flat, and is nontoxic, GUIXIN, spleen, liver, gallbladder meridian.Have nourishing the liver, mind calming is calmed the nerves, the arresting sweating effect.Be used to control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.
6, Fructus Amomi: Fructus Amomi (Radix Aconiti Ecalcarati), another name: husky honey, the Fructus Amomi that contracts, Fructus Amomi, fructus amomi, sweet Fructus Amomi contract.Acrid in the mouth, warm in nature, return spleen, stomach, kidney channel.Have the removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy.Be used for turbid damp obstructing in middle-JIAO, the gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
7, Semen Ricini: Semen Ricini (Ricinus communis L.), another name: Fructus Gastrodiae fruit, red Semen Ricini, Semen Ricini.Sweet in the mouth, suffering, property is flat, and is slightly poisonous, returns liver, spleen, stomach, large intestine channel.Have and relieve internal heat anticancerly, detumescence is logical to stagnate, and rushes down intestinal stasis relieving down, the sharp key effect of collateral dredging.Be used for the blood capillary cancer, skin carcinoma, the cellulitis toxic swelling, scrofula, acute mastitis, sore throat, mange tinea skin ulcer is scalded edema distension, constipation due to dry stool, facial hemiparalysis, traumatic injury.
8, Semen Sesami Nigrum core: Semen Sesami Nigrum core (Sesamum indicum L.), another name: Semen Sesami, black fiber crops, huge victory, Canis familiaris L. louse, friendship fiber crops, fructus leonuri.Bitter in the mouth, warm in nature is gone into kidney channel.Has the eliminating inflammation and expelling toxin effect.Be used for stagnation of blood stasis.
9, Semen Canarii albi: Semen Canarii albi [Canarium album (Lour.) Raeusch.].Sweet in the mouth, property is flat, returns lung, spleen, stomach warp.Have and moisturize, sober up, detoxicating functions.Be used for the dry pain of lip, drunk, chickenpox, alimentary toxicosis.There is history in several thousand in coastwise contries to olive oil in Mediterranean, are described as " liquid golden " " vegetable oil queen " in the west; Have splendid natural health and beauty functions; Can eliminate facial wrinkle and mottle stricture of vagina, prevent skin aging, ultraviolet rays resistance prevents radioprotective.
The present invention is achieved in that
A kind of Chinese medicine nine core cream of nourishing face, Chinese medicine preparation and parts by weight: Semen Armeniacae Amarum 3-10 part, Semen Coicis 9-30 part, Fructus Cannabis 9-15 part, Semen Persicae 4.5-9 part, Semen Ziziphi Spinosae 9-15 part, Fructus Amomi 3-6 part, Semen Ricini 1-5 part, Semen Sesami Nigrum core 15-30 part and Semen Canarii albi 3-6 part.
Above-described Chinese medicine nine core cream of nourishing face, Chinese medicinal components and parts by weight: 4 parts of 7 parts in Semen Armeniacae Amarum, 20 parts of Semen Coicis, 10 parts of Fructus Cannabiss, 7 parts in Semen Persicae, 10 parts of Semen Ziziphi Spinosaes, 5 parts of Fructus Amomis, 3 parts of Semen Ricinis, 22 parts of Semen Sesami Nigrum core and Semen Canarii albis.
The method for preparing of above-described Chinese medicine nine core cream of nourishing face comprises Chinese medicine extracts active ingredients, decolouring and preparation unguentum, and described Chinese medicine extracts active ingredients is earlier Chinese medicine to be adopted carbon dioxide supercritical fluid extraction, and the supercritical extraction Chinese medicine extract is subsequent use; Again the supercritical extraction Chinese medicine slag is adopted the carbonic ester extraction, carbonic ester extraction solution vacuum concentration obtains the thick cream of carbonic ester extraction Chinese medicine; At last the Chinese medicine slag recirculation water is carried, water is carried the Chinese medicine extract vacuum concentration and is obtained water and carry the thick cream of Chinese medicine; Described decolouring is that Chinese medicine extract and the thick cream of Chinese medicine are dissolved in the ethanol water that determining alcohol is 45-80%; Add activated carbon decolorizing; Filter; Concentrate and obtain the Chinese medicine clear paste, reclaim ethanol water and active carbon and reuse, then Chinese medicine extract and the mixing of Chinese medicine clear paste are prepared Chinese medicine nine core cream of nourishing face with the cream ointment conventional method.
Above-described carbon dioxide supercritical fluid extraction; Clean botanical herbs is ground into 30-100 order coarse powder with pulverizer to be dropped into the Chinese medicine coarse powder in the supercritical extraction device again; The control extracting pressure is 12-35Mpa, and extraction temperature is 30-50 ℃, and the extraction time is 0.5-2 hour; Carbon dioxide flow is 16-40kg/ hour, and extraction obtains supercritical collection Chinese medicine extract.
Above-described carbonic ester extraction is adopted the carbonic ester extractant with Chinese medicine slag, and the moisture content of control Chinese medicine slag is less than 15%, and the ratio of weight and number of Chinese medicine slag and solvent is 1: 1-4; Extraction temperature is 30-90 ℃, and the time is 10-120min, extracted twice; Obtain the carbonic ester extraction solution; With 55-80 ℃ of carbonic ester extraction solution control temperature, under nitrogen, carbon dioxide and argon shield, carry out vacuum concentration and obtain the thick cream of carbonic ester extraction Chinese medicine, reclaim carbonate solvent and reuse.
Above-described carbonic ester comprises in DMC dimethyl carbonate, diethyl carbonate, dipropyl carbonate and the dibutyl carbonate one or more.
Above-described recirculation water is carried; Be will be in the Chinese medicine slag input backflow digester of carbonic ester extraction; Add Chinese medicine slag 4-6 water doubly, 85-100 ℃ of control temperature, the decocting in water time is that 1-2.5 hour recirculation water carried; Filtration obtains water and carries solution, and water is carried 55-80 ℃ of vacuum concentration of solution control temperature and obtained water and carry the thick cream of Chinese medicine.
Advantage of the present invention and good effect:
1, these article employing Chinese medicine is raw material, has treating both the principal and secondary aspects of a disease, has no side effect, and to the skin nonirritant, emulsion particle is fine and smooth, and coating is even, and feel is cunning, and spreadability is good.Have powerful eliminating metabolic waste and free oxygen free radical, suppress cheese ammonia enzymatic activity; Can middle pharmaceutically active ingredient be infiltrated into the skin internal layer, promote the absorption of effective ingredient, promote skin metabolism; Dispelling stain; Make extensive high resilience of skin and vigor, skin is ruddy, lubricated and be rich in gloss, reaches the effect of skin care and skin whitening.
2, this method for preparing adopts supercritical extraction, carbonic ester extraction and water extracting method to combine, and has overcome traditional emollient cream, and freckle effect is relatively poor, and contains synthetics, and zest is bigger, the shortcoming that abnormal smells from the patient is relatively poor.Overcome existing Chinese medicine emollient cream because there are a lot of drawbacks in its extracts active ingredients with steam distillation preparation technology; Extraction ratio is higher, can the composition of some high boiling point and low volatility all be extracted, and the volatile ingredient of medicine is not easy loss; Being prone to pyrolytic material or chemical instability composition is protected; The loss of effective components of medicine is less, can effectively extract the effective ingredient in Chinese composition, improves the function of Chinese medicine; And practice thrift limited and the high Chinese medicine of valency money is former, have favorable economic benefit and social benefit.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail, listed embodiment only is the present invention is described and never is limited to the present invention.
Embodiment 1
(1) Chinese medicine preparation:
0.4 kilogram of 0.7 kilogram in Semen Armeniacae Amarum, 2 kilograms of Semen Coicis, 1 kilogram of Fructus Cannabis, 0.7 kilogram in Semen Persicae, 1 kilogram of Semen Ziziphi Spinosae, 0.5 kilogram of Fructus Amomi, 0.3 kilogram of Semen Ricini, 2.2 kilograms of Semen Sesami Nigrum core and Semen Canarii albi.
(2) method for preparing:
Clean botanical herbs is ground into 60 order Chinese medicine coarse powder with pulverizer; With carrying out carbon dioxide supercritical fluid extraction in the Chinese medicine coarse powder input supercritical extraction device; The control extracting pressure is 15Mpa; Extraction temperature is 40 ℃, and the extraction time is 1.5 hours, and carbon dioxide flow is to obtain supercritical extract in 23kg/ hour.Medicinal residues control moisture content 13% through supercritical extraction drops in the carbonic ester extractor, and the ratio of weight and number that adds medicinal residues and solvent is 1: 3 a diethyl carbonate; The control extraction temperature is 60 ℃, and the time is 60min, extracted twice; Obtain the carbonic ester extraction solution; 75 ℃ of carbonic ester extraction solution control temperature are carried out vacuum concentration and are obtained the thick cream of carbonic ester extraction Chinese medicine under argon shield, reclaim carbonate solvent and reuse.Carbonic ester extraction medicinal residues add the water of 6 times of Chinese medicine slags, 100 ℃ of control temperature, and the decocting in water time is that 1 hour recirculation water is carried, and filtration obtains water and carries solution, and water is put forward 50 ℃ of solution control temperature, and vacuum concentration obtains water and carries the thick cream of Chinese medicine, reclaims alcoholic solution; It is in 50% the ethanol water that Chinese medicine supercritical extract and the thick cream of Chinese medicine are dissolved in concentration, adds activated carbon decolorizing, filters, and adopts conventional vacuum concentration to obtain Chinese medicine extract, recovered carbon and ethanol; At last Chinese medicine extract and Chinese medicine clear paste are mixed, adopt conventional substrate and method for preparing emulsifying, homogenizing obtains Chinese medicine Chinese medicine nine core cream of nourishing face.
Embodiment 2
(1) Chinese medicine preparation:
0.6 kilogram of 0.3 kilogram in Semen Armeniacae Amarum, 3 kilograms of Semen Coicis, 1.5 kilograms of Fructus Cannabiss, 0.45 kilogram in Semen Persicae, 1.5 kilograms of Semen Ziziphi Spinosaes, 0.3 kilogram of Fructus Amomi, 0.5 kilogram of Semen Ricini, 1.5 kilograms of Semen Sesami Nigrum core and Semen Canarii albi.
(2) method for preparing:
Clean botanical herbs is ground into 30 order Chinese medicine coarse powder with pulverizer; With carrying out carbon dioxide supercritical fluid extraction in the Chinese medicine coarse powder input supercritical extraction device; The control extracting pressure is 12Mpa; Extraction temperature is 30 ℃, and the extraction time is 1 hour, and carbon dioxide flow is to obtain supercritical extract in 20kg/ hour.Medicinal residues control moisture content 13% through supercritical extraction drops in the carbonic ester extractor, and the ratio of weight and number that adds medicinal residues and solvent is 1: 4 a DMC dimethyl carbonate 3; The control extraction temperature is 30 ℃, and the time is 90min, extracted twice; Obtain the carbonic ester extraction solution; 55 ℃ of carbonic ester extraction solution control temperature are carried out vacuum concentration and are obtained the thick cream of carbonic ester extraction Chinese medicine under carbon-dioxide protecting, reclaim carbonate solvent and reuse.Carbonic ester extraction medicinal residues add the water of 5 times of Chinese medicine slags, 85 ℃ of control temperature, and the decocting in water time is that 2 hours recirculation waters are carried, and filtration obtains water and carries solution, and water is put forward 65 ℃ of solution control temperature, and vacuum concentration obtains water and carries the thick cream of Chinese medicine, reclaims alcoholic solution; It is in 70% the ethanol water that Chinese medicine supercritical extract and the thick cream of Chinese medicine are dissolved in concentration, adds activated carbon decolorizing, filters, and adopts conventional vacuum concentration to obtain Chinese medicine extract, recovered carbon and ethanol; At last Chinese medicine extract and Chinese medicine clear paste are mixed, adopt conventional substrate and method for preparing emulsifying, homogenizing obtains Chinese medicine Chinese medicine nine core cream of nourishing face.
Embodiment 3
(1) Chinese medicine preparation:
0.3 kilogram of 1 kilogram in Semen Armeniacae Amarum, 0.9 kilogram of Semen Coicis, 0.9 kilogram of Fructus Cannabis, 0.9 kilogram in Semen Persicae, 0.9 kilogram of Semen Ziziphi Spinosae, 0.6 kilogram of Fructus Amomi, 0.1 kilogram of Semen Ricini, 3 kilograms of Semen Sesami Nigrum core and Semen Canarii albi.
(2) method for preparing:
Clean botanical herbs is ground into 100 order Chinese medicine coarse powder with pulverizer; With carrying out carbon dioxide supercritical fluid extraction in the Chinese medicine coarse powder input supercritical extraction device; The control extracting pressure is 35Mpa; Extraction temperature is 35 ℃, and the extraction time is 0.5 hour, and carbon dioxide flow is to obtain supercritical extract in 40kg/ hour.Through the medicinal residues of supercritical extraction control moisture content 15%, drop in the carbonic ester extractor, the ratio of weight and number that adds medicinal residues and solvent is in 1: 2 the dibutyl carbonate; The control extraction temperature is 90 ℃, and the time is 80min, extracted twice; Obtain the carbonic ester extraction solution; 60 ℃ of carbonic ester extraction solution control temperature are carried out vacuum concentration and are obtained the thick cream of carbonic ester extraction Chinese medicine under nitrogen protection, reclaim carbonate solvent and reuse.Carbonic ester extraction medicinal residues add the water of 4 times of Chinese medicine slags, 95 ℃ of control temperature, and the decocting in water time is that 2.5 hours recirculation waters are carried, and filtration obtains water and carries solution, and water is put forward 75 ℃ of solution control temperature, and vacuum concentration obtains water and carries the thick cream of Chinese medicine, reclaims alcoholic solution; It is in 55% the ethanol water that Chinese medicine supercritical extract and the thick cream of Chinese medicine are dissolved in concentration, adds activated carbon decolorizing, filters, and adopts conventional vacuum concentration to obtain Chinese medicine extract, recovered carbon and ethanol; At last Chinese medicine extract and Chinese medicine clear paste are mixed, adopt conventional substrate and method for preparing emulsifying, homogenizing obtains Chinese medicine nine core cream of nourishing face.
Application example:
1, land X: women, 29 years old age, occupation: teacher.Skin symptom: face's colour of skin is obscure, and mottle is that distribution is distributed at the center with the face cheekbone.Before the use, the colour of skin is black, and speckle is obvious, trial edition embodiment 1 product.Every night, sleep was previous hour, with behind the suds cleaning face, present embodiment 1 product was evenly spread upon 40 minutes on the face earlier, cleaned up cream of nourishing face with warm water then, and facial skin improved in 14 days; Facial skin splash deepening in 28 days is thin out, and rear face skin black speck reduced the 70-80% that disappeared in 35 days; After adhering to using 60 days, face's speckle disappears, and the colour of skin is ruddy, and the surface is delicate lubricated, glossy.
2, Lee XX: women, 43 years old age, occupation: bank clerk.Skin symptom: skin of face is dark, and nonelastic, freckle is obvious.Before the use, born skin is black partially, and freckle is from spread to left face and chin trial edition embodiment 2 products now gradually.The back get up every morning earlier with suds cleaning face, again present embodiment 2 products are evenly spread upon 20 minutes on the face, clean up cream of nourishing face with warm water then, the reusable heat towel applied 5 minutes; Half an hour before the sleep in evening, with behind the facial milk cleanser cleaning face present embodiment 2 products evenly being spread upon 20 minutes on the face, clean up cream of nourishing face then with clear water earlier, and the reuse cold pack applied 5 minutes.Facial skin improved in 10 days; Facial skin freckle desalination in 20 days, skin is flexible than before, and 40 days rear face skin is from original partially black and thin out, and freckle reduces gradually, uses 60 days, and freckle disappears 80%, and the colour of skin is ruddy, and smooth surface is flexible.Adhered to using 3 months, the freckle complete obiteration, the colour of skin is delicate general ruddy, the smooth surface high resilience.
3, woods XX: women, 36 years old age, occupation: the senior executive of enterprise.Skin characteristic: skin of face is dark yellow, speckle cloud and mist situation in blocks many places.Before the trial edition cream of nourishing face, owing to use the skin-lightening cosmetic of import, skin exfoliation is serious, and it is matt to form the colour of skin, has disperseed many specklees around the nose, and is general a little red.Trial edition embodiment 3 products applied 30 minutes present embodiment 3 products are thick with warm water cleaning face earlier more early, middle and late three times of every day, cleaned up with warm water afterwards.Facial skin exfoliation improved in 21 days; Speckle desalination in 35 days, the cloud speckle disappears in flakes, and general red blotchy skin has clear improvement; The skin of general red stain has been replied the normal colour of skin after 49 days, uses after 70 days, and all ill symptomses of skin of face disappear, and blee is ruddy, and surface lubrication is glossy.
Claims (7)
1. Chinese medicine nine core cream of nourishing face is characterized in that: Chinese medicine preparation and parts by weight: Semen Armeniacae Amarum 3-10 part, Semen Coicis 9-30 part, Fructus Cannabis 9-15 part, Semen Persicae 4.5-9 part, Semen Ziziphi Spinosae 9-15 part, Fructus Amomi 3-6 part, Semen Ricini 1-5 part, Semen Sesami Nigrum core 15-30 part and Semen Canarii albi 3-6 part.
2. Chinese medicine nine core cream of nourishing face according to claim 1 is characterized in that: described Chinese medicinal components and parts by weight: 4 parts of 7 parts in Semen Armeniacae Amarum, 20 parts of Semen Coicis, 10 parts of Fructus Cannabiss, 7 parts in Semen Persicae, 10 parts of Semen Ziziphi Spinosaes, 5 parts of Fructus Amomis, 3 parts of Semen Ricinis, 22 parts of Semen Sesami Nigrum core and Semen Canarii albis.
3. the method for preparing of Chinese medicine nine core cream of nourishing face according to claim 1 and 2; Comprise Chinese medicine extracts active ingredients, decolouring and preparation unguentum; It is characterized in that: described Chinese medicine extracts active ingredients is earlier Chinese medicine to be adopted carbon dioxide supercritical fluid extraction, and the supercritical extraction Chinese medicine extract is subsequent use; Again the supercritical extraction Chinese medicine slag is adopted the carbonic ester extraction, concentrate and obtain the thick cream of carbonic ester extraction Chinese medicine; At last the Chinese medicine slag recirculation water is carried, vacuum concentration obtains water and carries the thick cream of Chinese medicine; Described decolouring is that Chinese medicine extract and the thick cream of Chinese medicine are dissolved in the ethanol water that determining alcohol is 45-80%; Add activated carbon decolorizing; Filter; Concentrate and obtain the Chinese medicine clear paste, reclaim ethanol water and active carbon and reuse, then Chinese medicine extract and the mixing of Chinese medicine clear paste are prepared Chinese medicine nine core cream of nourishing face with the cream ointment conventional method.
4. the method for preparing of Chinese medicine nine core cream of nourishing face according to claim 3; It is characterized in that: described carbon dioxide supercritical fluid extraction, clean botanical herbs is ground into 30-100 order coarse powder with pulverizer again the Chinese medicine coarse powder is dropped in the supercritical extraction device, the control extracting pressure is 12-35Mpa; Extraction temperature is 30-50 ℃; The extraction time is 0.5-2 hour, and carbon dioxide flow is 16-40kg/ hour, and extraction obtains supercritical collection Chinese medicine extract.
5. the method for preparing of Chinese medicine nine core cream of nourishing face according to claim 3 is characterized in that: described carbonic ester extraction is adopted the carbonic ester extractant with Chinese medicine slag, and the moisture content of control Chinese medicine slag is less than 15%; The ratio of weight and number of Chinese medicine slag and solvent is 1: 1-4; Extraction temperature is 30-90 ℃, and the time is 10-120min, extracted twice; Obtain the carbonic ester extraction solution; With 55-80 ℃ of carbonic ester extraction solution control temperature, under nitrogen, carbon dioxide and argon shield, carry out vacuum concentration and obtain the thick cream of carbonic ester extraction Chinese medicine, reclaim carbonate solvent and reuse.
6. the method for preparing of Chinese medicine nine core cream of nourishing face according to claim 3 is characterized in that: described carbonic ester comprises in DMC dimethyl carbonate, diethyl carbonate, dipropyl carbonate and the dibutyl carbonate one or more.
7. the method for preparing of Chinese medicine nine core cream of nourishing face according to claim 3; It is characterized in that: described recirculation water is carried, and is with in the Chinese medicine slag input backflow digester of carbonic ester extraction, adds Chinese medicine slag 4-6 water doubly; 85-100 ℃ of control temperature; The decocting in water time is that 1-2.5 hour recirculation water carried, and filters to obtain water and carry solution, and water is carried 55-80 ℃ of vacuum concentration of solution control temperature and obtained water and carry the thick cream of Chinese medicine.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103860447A (en) * | 2014-03-16 | 2014-06-18 | 董青芳 | Beautifying and moisturizing cream and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1618461A (en) * | 2004-07-19 | 2005-05-25 | 王成余 | Composition of nano-SOD and vegetative medicine or its extractives, and its prepn. method |
| CN1618462A (en) * | 2004-07-19 | 2005-05-25 | 王成余 | Compositions of SOD and vetetative medicine or its extractives, and its prepn. method |
| CN101954070A (en) * | 2009-07-13 | 2011-01-26 | 陈洁 | Preparation method of composition of nano SOD and vegetable drugs and health-care food or extracts thereof |
| CN102014940A (en) * | 2008-05-02 | 2011-04-13 | 株式会社太平洋 | Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1618461A (en) * | 2004-07-19 | 2005-05-25 | 王成余 | Composition of nano-SOD and vegetative medicine or its extractives, and its prepn. method |
| CN1618462A (en) * | 2004-07-19 | 2005-05-25 | 王成余 | Compositions of SOD and vetetative medicine or its extractives, and its prepn. method |
| CN102014940A (en) * | 2008-05-02 | 2011-04-13 | 株式会社太平洋 | Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same |
| CN101954070A (en) * | 2009-07-13 | 2011-01-26 | 陈洁 | Preparation method of composition of nano SOD and vegetable drugs and health-care food or extracts thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860447A (en) * | 2014-03-16 | 2014-06-18 | 董青芳 | Beautifying and moisturizing cream and preparation method thereof |
| CN103860447B (en) * | 2014-03-16 | 2016-08-17 | 尹仕红 | Cream and preparation method thereof is moistened in a kind of skin care |
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