CN102631518B - New medicament for treating leukemia - Google Patents

New medicament for treating leukemia Download PDF

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CN102631518B
CN102631518B CN201210094444.7A CN201210094444A CN102631518B CN 102631518 B CN102631518 B CN 102631518B CN 201210094444 A CN201210094444 A CN 201210094444A CN 102631518 B CN102631518 B CN 102631518B
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radix
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herba
rhizoma
leukemia
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CN102631518A (en
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罗心刚
燕学生
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HUNAN INNOVATION CHINESE MEDICINE RESEARCH Co Ltd
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Abstract

The invention provides a new medicament for treating leukemia, which is prepared from 39 raw material drugs, such as taxus chinensis (tree bark), tender catchweed bedstraw herb, prismatomeria tetrandra, isatis indigotica fort, tuber fleeceflower stem, Yunnan fringed iris herb, fructus corni, hemlock parsley, turtle shell and the like, wherein the taxus chinensis (tree bark) contains 'taxol' which is the top anti-cancer medicament in the world, can be combined with trace of albumin, so that the albumin is accelerated to be aggregated, mitosis of cancer cells can be inhibited, and proliferation of the cancer cells can be effectively stopped. The medicament also comprises the tender catchweed bedstraw herb, suncured ginseng, prismatomeria tetrandra, isatis indigotica fort, tuber fleeceflower stem, Yunnan fringed iris herb, fructus corni, hemlock parsley and turtle shell, so that growth and development of the cancer cells can be controlled, the cancer resistance of a human body can be reinforced, the circulation and metabolic function of the human body can be improved, virus accumulated in the human body is removed outside the body through urine and defecation to achieve the function of preventing cancer. The medicament adopts the Chinese medicaments capable of nourishing yin and supplementing kidney, supplying vital energy, nourishing and activating blood, tonifying qi and controlling blood, softening hardness to dissipate stagnation, removing toxicity and tonifying middle-Jiao and coordinating drug actions of a prescription, administration is increased or reduced according to the course development and classification of the leukemia to achieve the best treatment effect. 38 leukemia cases are treated non-selectively in clinical application, and the total effective rate is over 90 percent.

Description

A kind of new drug for the treatment of leukemia
Technical field
The present invention relates to a kind of new drug for the treatment of leukemia, belong to technical field of Chinese medicines.
Background technology
Leukemia is medically referred to as leukemia, is the incurable disease that threatens people's life.At present, the Therapeutic Method medically adopting is blood transfusion, radiotherapy, chemotherapy or bone marrow transplantation etc.The toxic and side effects of these Therapeutic Method is large, and the treatment phase is long, expense high (bone marrow transplantation is minimum more than 400,000 yuans, and is difficult for joining type), and general patient is difficult to afford, and effect is also undesirable, Chinese medicine treatment leukemia is with a long history, at < < Compendium of Materia Medica > >, the < < book on Chinese herbal medicine > > that looks for the truth, all on the books in the medical science works such as the complete works of > > of < < surgeon, think the generation of cancer be human body oncogene and tumor repressive gene unbalance due to, unbalance basic reason is immune problem, regulate immune system, in conjunction with containing anticancer composition in Chinese medicine, can fundamentally treat cancer, therefore extensive patients wish very much that a kind of expense is low, instant effect, the eutherapeutic Chinese medicine of controlling leukemia, in order to alleviate the misery on patient body, reduce treatment cost, promote social progress.
Summary of the invention
For overcoming the above-mentioned defect of existing treatment leukemia medicine, the object of this invention is to provide the new drug for the treatment of leukemia.
The inventor just follows old Chinese medicine master worker to work as apprentice from the seventies, start the beginning of the nineties to work as apprentice with old docter of TCM, on Chinese medicine post, adhere to clinical practice always, through practice and research for many years, finally sum up a kind of loose > > of new drug < < leukemia that treats leukemia, its technical characterstic is: the present invention adopts Chinese herbal medicine Ramulus et folium taxi cuspidatae, Galium spurium L., Radix Ginseng, xanthorrhiza, Radix Isatidis, Rohdea japonica, Caulis Polygoni Multiflori, Rhizoma Chuanxiong, Fructus Corni, Carapax Trionycis, Ganoderma, Herba Hedyotidis Diffusae, Rhizoma Dioscoreae Bulbiferae, the Radix Astragali, Herba Solani Lyrati, the Cortex Eucommiae, Caulis Polygoni Multiflori, Fructus Corni, Rhizomadioscoreae, Herba Scutellariae Barbatae 20 taste Chinese herbal medicine, by traditional conventional method, be mixed with tablet or capsule is taken, through tens case clinical practices, cure to hold and reach more than 90%, cost is low, effective.
The loose medicine of leukemia of the present invention is comprised of the herbal raw material of following weight parts: Ramulus et folium taxi cuspidatae 3-5 part, Galium spurium L. 4-6 part, xanthorrhiza 2-4 part, Radix Isatidis 1-2 part, Caulis Polygoni Multiflori 0.5-1, Yunnan Rohdea japonica 1-2 part, Fructus Corni 1-3 part, Rhizoma Chuanxiong 1-2 part, Carapax Trionycis 0.5-1, Ganoderma 1-2 part, Herba Hedyotidis Diffusae 1-2 part, Rhizoma Dioscoreae Bulbiferae 0.5-1 part, Herba Solani Lyrati 1-2 part, Cortex Eucommiae 1-1.5 part, Radix Polygoni Multiflori 0.5-1 part, Rhizomadioscoreae 1-1.5 part, Radix Rehmanniae 0.5-1 part, Radix Rehmanniae Preparata 0.5-1 part, Herba Taraxaci 0.5-1 part, Poria cum Radix Pini 0.5-1 part, Fructus Lycii 0.5-1 part, Radix Salviae Miltiorrhizae 0.5-1 part, Herba Violae 0.5-1 part, Herba Scutellariae Barbatae 0.5-1 part, Fructus Ligustri Lucidi 0.5-1 part, Semen Cuscutae 0.5-1 part, Rhizoma Sparganii 0.5-1 part, Rhizoma Curcumae 0.5-1 part, Radix Angelicae Sinensis 0.1-0.5 part, Flos Carthami 0.5-1 part, Rhizoma Polygonati 0.1-0.5 part, Radix Dipsaci 0.1-0.5 part, Radix Ginseng Rubra 0.01-0.05 part, Radix Ginseng 0.1-0.5 part, Fructus Schisandrae Chinensis 0.1-0.5 part, Radix Glycyrrhizae 0.1-0.5 part, Indigo Naturalis 0.1-0.5 part, Realgar 0.01-0.05 part is totally 38 taste medicines.
The present invention adopts Radix Salviae Miltiorrhizae, Rhizoma Sparganii, Rhizoma Curcumae, Rhizoma Chuanxiong, Flos Carthami, for blood circulation promoting and blood stasis dispelling; Adopt Ramulus et folium taxi cuspidatae, Ganoderma, Indigo Naturalis, Realgar, Herba Scutellariae Barbatae, Rhizoma Dioscoreae Bulbiferae, Herba Violae, Herba Solani Lyrati, Herba Taraxaci, Herba Hedyotidis Diffusae, Rhizoma Sparganii, Rhizoma Curcumae, be used for heat-clearing and toxic substances removing there is anticancer effect; Employing Carapax Trionycis is hard masses softening and resolving; Adopting Fructus Lycii, the Radix Rehmanniae, Radix Rehmanniae Preparata, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis is enriching yin and nourishing kidney; Adopt Radix Ginseng Rubra, Radix Ginseng in order to invigorating primordial QI; With working as, be classified as nourshing blood and promoting blood circulation; With Radix Glycyrrhizae, Rhizoma Polygonati, it is nourishing qi to stop; With Radix Glycyrrhizae, be removing toxic substances invigorating middle warmer, coordinating the actions of various ingredients in a prescription.
The scope of application of medicine of the present invention: leukemia: acute lymphoblastic leukemia (ALL), acute nonlymphocytic leukemia (ANLL); Acute myeloid leukaemia (AML), chronic lymphocytic leukemia (CLL); Chronic myelogenous leukemia (CML); Chronic myelocytic leukemia; Polycythemia vera.Medicine of the present invention is to hepatocarcinoma in addition; Esophageal carcinoma; Pulmonary carcinoma also has certain curative effect.The using method of medicine of the present invention: 1. because acute leukemia is former malignant hematologic disease of one group of hemopoietic tissue, in bone marrow and other hemopoietic tissue, there is widely leukaemia's paraplasm and infiltrate other histoorgans, cause normal hematopoiesis nonfunction, show as normal hematopoiesis cell and significantly reduce; Chronic myelogenous leukemia (CML) is a kind of clone's property disease being caused by pluripotent stem cell sudden change, with ripe granulocyte and antecedent thereof, comprises grain system, and monokaryon system, red system and megakaryocytic series and some bone-marrow-derived lymphocytes are hypertrophy and accumulate for feature; According to clinical minute three phases of disease: chronic phase, accelerated period, acute transformation phase.2. because chronic lymphocytic leukemia (CLL) is a kind of mature lymphocyte propagation and accumulate the variability disease as feature of take in blood, bone marrow, lymph node, liver, spleen and other organ pipe.Therefore according to different the distinguish drug treatments different from leukemic classification of the state of an illness.3 times on the one, each 15 grams, take half an hour after meal.Two months courses for the treatment of, can cure general 3~5 courses for the treatment of, and cure rate can reach more than 90%.
The preparation method for the treatment of leukemia new drug of the present invention: first by Ramulus et folium taxi cuspidatae, Galium spurium L., Radix Ginseng, xanthorrhiza, Radix Isatidis, Caulis Polygoni Multiflori, Yunnan Rohdea japonica, Fructus Corni, Rhizoma Chuanxiong, Carapax Trionycis, Ganoderma, Herba Hedyotidis Diffusae, Rhizoma Dioscoreae Bulbiferae, Herba Solani Lyrati, the Cortex Eucommiae, Radix Polygoni Multiflori, Rhizomadioscoreae, the Radix Rehmanniae, Radix Rehmanniae Preparata, Herba Taraxaci, Poria cum Radix Pini, Fructus Lycii, Radix Salviae Miltiorrhizae, Herba Violae, Herba Scutellariae Barbatae, Fructus Ligustri Lucidi, Semen Cuscutae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Polygonati, Radix Dipsaci, Radix Ginseng Rubra, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Indigo Naturalis and Realgar totally 38 taste Chinese medicines are assorted according to quantity, dry, difference pulverization, mixing is mixed thoroughly, through three steamings three, shine again, then by conventional method, be pressed into tablet or record into capsule.
Compare with existing treatment leukemia medicine, the present invention has following substantive distinguishing features and marked improvement: 1. this medicine has adopted Ramulus et folium taxi cuspidatae as principal agent, because contain the No.1 cancer therapy drug in the world " paclitaxel " in Ramulus et folium taxi cuspidatae, its mechanism of action is exactly that paclitaxel can be combined with trace albumin, and promote its polymerization, the mitosis of anticancer, effectively stops the propagation of cancerous cell.In medicine, also have Galium spurium L., Radix Ginseng, xanthorrhiza, Radix Isatidis, Caulis Polygoni Multiflori, Yunnan Rohdea japonica, Fructus Corni, Rhizoma Chuanxiong, Carapax Trionycis, thereby control the advolution of cancerous cell, strengthen the anti-cancer ability of human body, can also improve circulation and the metabolic function of human body simultaneously, make to be accumulated in virus in human body by diuresis, defecation, be scavenged into externally, reach the effect of prophylaxis of cancer.2. this medicine adopts the Chinese medicine of relevant enriching yin and nourishing kidney, supplementary vigour, nourshing blood and promoting blood circulation, nourishing qi to stop, hard masses softening and resolving and removing toxic substances invigorating middle warmer, coordinating the actions of various ingredients in a prescription, according to leukemic disease and classification, adds and subtracts respectively administration, reaches best therapeutic effect; To the high leukemia of leukocyte and all kinds of terminal cancer that are transferred to skeleton also successful.3. evident in efficacy: according to clinical, without selecting various leukemia 38 examples for the treatment of, total effective rate is more than 90%, best with the anxious curative effect of drenching, and is secondly very red and slow grain, and early the anxious single current system effect of children's grain is taken second place.
The specific embodiment
Below in conjunction with clinical observation material and embodiment, beneficial effect of the present invention is further illustrated:
Embodiment 1: clinical observation treatment:
One, physical data: cure altogether and treat leukaemic and treat various leukemia 38 examples, male 22 examples wherein, female's 16 examples: anxious grain 5 examples, anxious single 4 examples, anxious 10 examples, very red 6 examples of drenching; Slow grain 3 examples, drench 3 examples slowly, children's grain 2 examples early, preleukemia 5 examples.Total effective rate is more than 90%, best with the anxious curative effect of drenching, and is secondly very red and slow grain, and early the anxious single current system effect of children's grain is taken second place;
Two, diagnostic criteria: leukemia is the pathological changes of bone marrow, therefore need to carry out bone marrow aspiration inspection and Sections of Bone Marrow inspection, can determine diagnosis.In order further to confirm leukemic kind also to need extra special examined, could accurately leukemia be classified and be given optimal treatment.These special examineds comprise: cellular biochemical specific stain, flow cytometer inspection, chromosome examination.General standard is mostly with 1. hemogram: numeration of leukocyte is high more than 100 * 109/L, is mostly neutral band form nucleus and metamyelocyte in blood sheet, and all the other are leaflet core, middle children's grain, early children's grain and minority myeloblast.Acidophilia and basophilic granulocyte also increase.Early stage hemoglobin and erythrocyte slightly reduce, and platelet is normal or increase, late period erythrocyte and thrombocytopenia.Aspect hemogram, must differentiate mutually with leukemoid reaction; 2. bone marrow smear: bone marrow is hypertrophy obviously to extremely active, cell divide is similar to Peripheral blood, in bone marrow sheet, can see each phase granulocyte, in wherein take, evening children grain is as main, a myeloblast early children grain compared with normal increases, but is generally no more than 5%~10%, have a liking for acid and (or) basophilia, erythron reduces relatively, grain: red approximately 10~50:1, normoblast and megalokaryocyte often increase in early days, and reduce late period.The active obviously reduction of neutrophil alkaline phosphatase of 90% patient's maturation; 3. chromosome examination: Ph chromosome sees more than 90% slow granulosis people.Ph chromosome is considered to the tumprigenicity sign of slow grain pluripotent stem cell, the slow granulosis people Ph of minority chromosome is negative, according to having or not Ph chromosome, can be the Ph positive and the negative two large classes of Ph by slow grain, the former be better than the latter at prevention, and other cancer diagnosis standard is pressed hospital diagnosis conclusion;
Three, Therapeutic Method: according to patient's leukemic classification of institute and time length, with the loose drug treatment respectively of leukemia, 3 times on the one, each 10~15 grams, take half an hour after meal; Within two months, be a course for the treatment of, can cure general 3~5 courses for the treatment of, and cure rate can reach more than 90%;
Four, criterion of therapeutical effect:
Acute leukemia criterion of therapeutical effect:
1. alleviation standard:
(1) alleviate (CR) completely: 1. bone marrow smear: myeloblast I type+II type (former list+children single or former pouring+children pouring) is less than or equal to 5%, and erythrocyte and megalokaryocyte are normal; 2. hemogram: male's hemoglobin is more than or equal to 100g/L, and women and blood of children Lactoferrin are more than or equal to 90g/L, and neutrophilic granulocyte absolute value is more than or equal to 1.5 109/L, and platelet is more than or equal to 100 109/L, and peripheral blood divides apoplexy due to endogenous wind without leukaemia; 3. clinical: the sings and symptoms due to infiltrating without leukemia, life is normal or approach normal;
(2) partial rcsponse (PR): be greater than 5% and be less than or equal to again 20%; Or there is one not reach above-mentioned standard person in 2 of clinical, hemogram;
(3) do not alleviate (NR): bone marrow smear, hemogram and clinical 3 all do not reach above-mentioned standard person.
2. recurrence standard: have following thrin person to be called recurrence:
(1) bone marrow myeloblast (former single, children is single, former pouring+children drenches) is greater than 5% and be less than 20%, through anti-doctor | and learn education network and collect arrangement leukemia treating and do not reach yet bone marrow alleviation person completely a course for the treatment of; (2) the former grain of bone marrow (former single, young single, former pouring) is greater than 20%; (3) the outer leukemiacell infiltration person of bone marrow;
3. continued complete remission: from alleviating completely, reach 3~5 years persons without leukemia relapse therebetween; 4. long-term surviving: leukemia is from make a definite diagnosis, and the time-to-live reaches 5 years or 5 years above persons;
5. clinical cure: refer to stop chemotherapy 5 years or disease free survival and reach 10 years persons;
Chronic myelocytic leukemia criterion of therapeutical effect:
1. alleviate completely: numeration of leukocyte <10 109/L; Classification is normal, without immature granulocyte (original, early, middle and late myelocyte).Platelet count is normally no more than 450 109/L;
2. partial rcsponse: it is front more than 50% that numeration of leukocyte is down to treatment, at least < 20*109/L; Leukocyte Counts is normal, but still has juvenile cell and splenomegaly;
3. invalid: clinical and experimental check does not reach binomial standard or deterioration;
4. the acellular hereditism's reaction of cytogenetic response: A., Ph1 chromosome continues to exist in all divisions mutually; B. small cytogenetic response: Ph1 chromosome is suppressed to accounting for 35%~95% of division phase; C. part cytogenetic response: Ph1 chromosome is suppressed to dividing 5%~34% of phase; D. complete cytogenetic response: Ph1 chromosome vanished cell;
Five, therapeutic outcome:
Treat various leukemia 38 examples, with 2~5 courses for the treatment of of medicine of the present invention plus-minus, male 22 examples wherein, female's 16 examples: anxious grain 5 examples, anxious single 4 examples, anxious 10 examples, very red 6 examples of drenching; Slow grain 3 examples, drench 3 examples slowly, children's grain 2 examples early, preleukemia 5 examples.Total effective rate is more than 90%, best with the anxious curative effect of drenching, and is secondly very red and slow grain, and early the anxious single current system effect of children's grain is taken second place.
Embodiment 2:: the preparation method 1 of the new drug for the treatment of leukemia of the present invention:
The preparation of medicine: take by weight ratio each crude drug: 3 parts of Ramulus et folium taxi cuspidatae, 4 parts of Galium spurium L.s, 1 part of Radix Ginseng, 2 parts of xanthorrhizas, 1 part of Radix Isatidis, 0.5 part of Caulis Polygoni Multiflori, 1 part of Yunnan Rohdea japonica, 1 part of Fructus Corni, 1 part of Rhizoma Chuanxiong, 0.5 part of Carapax Trionycis, 1 part of Ganoderma, 1 part of Herba Hedyotidis Diffusae, 0.5 part of Rhizoma Dioscoreae Bulbiferae, 1 part of Herba Solani Lyrati, 1 part of the Cortex Eucommiae, 0.5 part of Radix Polygoni Multiflori, 1 part of Rhizomadioscoreae, 0.5 part, the Radix Rehmanniae, 0.5 part, Radix Rehmanniae Preparata, 0.5 part of Herba Taraxaci, 0.5 part of Poria cum Radix Pini, 0.5 part of Fructus Lycii, 0.5 part of Radix Salviae Miltiorrhizae, 0.5 part of Herba Violae, 0.5 part of Herba Scutellariae Barbatae, 0.5 part of Fructus Ligustri Lucidi, 0.5 part of Semen Cuscutae, 0.5 part of Rhizoma Sparganii, 0.5 part of Rhizoma Curcumae, 0.1 part of Radix Angelicae Sinensis, 0.1 part, Flos Carthami, 0.1 part of Rhizoma Polygonati, 0.1 part of Radix Dipsaci, 0.01 part of Radix Ginseng Rubra, 0.1 part of Fructus Schisandrae Chinensis, 0.1 part, Radix Glycyrrhizae, 0.1 part of Indigo Naturalis, 0.01 part of Realgar, totally 38 taste Chinese medicines are assorted according to quantity, dry, difference pulverization, mixing is mixed thoroughly, through three steamings three, shine again, then compressed tablets or fill with into capsule according to a conventional method, every 1 gram, or 2 grams of every capsules.
Embodiment 3: the preparation method 2 of the new drug for the treatment of leukemia of the present invention:
The preparation of medicine: take by weight ratio each crude drug: 5 parts of Ramulus et folium taxi cuspidatae, 6 parts of Galium spurium L.s, 2 parts of Radix Ginseng, 4 parts of xanthorrhizas, 2 parts of Radix Isatidis, 1 part of Caulis Polygoni Multiflori, 2 parts of Yunnan Rohdea japonica, 3 parts of Fructus Cornis, 2 parts of Rhizoma Chuanxiongs, 1 part of Carapax Trionycis; 2 parts of Ganodermas, 1 part of Herba Hedyotidis Diffusae, 1 part of Rhizoma Dioscoreae Bulbiferae, 2 parts of Herba Solani Lyratis, 5 parts of the Cortexs Eucommiae, 1 part of Radix Polygoni Multiflori, 1.5 parts of Rhizomadioscoreae, 1 part, the Radix Rehmanniae, 1 part, Radix Rehmanniae Preparata, 1 part of Herba Taraxaci, 1 part of Poria cum Radix Pini, 1 part of Fructus Lycii, 0.5 part of Radix Salviae Miltiorrhizae, 0.5 part of Herba Violae, 1 part of Herba Scutellariae Barbatae, 1 part of Fructus Ligustri Lucidi, 1 part of Semen Cuscutae, 1 part of Rhizoma Sparganii, 1 part of Rhizoma Curcumae, 0.5 part of Radix Angelicae Sinensis, 1 part, Flos Carthami, 0.5 part of Rhizoma Polygonati, 0.5 part of Radix Dipsaci, 0.05 part of Radix Ginseng Rubra, 0.5 part of Fructus Schisandrae Chinensis, 0.5 part, Radix Glycyrrhizae, 0.5 part of Indigo Naturalis, 0.05 part of Realgar.Totally 38 taste Chinese medicines are assorted according to quantity, are dried, difference pulverization, and mixing is mixed thoroughly, then shines through three steamings three, is then pressed into according to a conventional method tablet or fills with into capsule; Every 1 gram, or 2 grams of every capsules.
Model case 1: poplar, male, 23 years old, people from Wuhan, Hubei, patient generated heat without obvious inducement before 10 days, 38.2 ℃ of body temperature, companion's systemic pain, slightly cough, cough the sticky expectorant of a little white, gingival hemorrhage while simultaneously finding to brush teeth, once " had abnormal " in local blood count, certainly took Coritab and failed to respond to any medical treatment to examine; Feed is after being ill few, sleeps poor, and two is just normal, and body weight is without significant change; Previously body is strong, without tuberculosis medical history, and medicine-less allergy history; Without habits of smoking and alcohol drinking, in family without similar medical history; Patient's symptom is anemia, hemorrhage, heating and infection etc.; Through certain hospital expert, be diagnosed as acute leukemia.Give chemotherapy regimen treatment; Once with multi-medicament treatments such as Busulfan, cyclophosphamide; The state of an illness is slightly stable, then both leaves hospital.See a doctor after being introduced: symptom and sign: dizzy, fatigue and weakness, 38 ℃ of low grade fever, often epistaxis, gingival hemorrhage, blood pressure 24/13kpa, 96 beats/min of pulsations, flushing, two conjunctival congestions, 2-3cm under hepatosplenomegaly rib, extremity are dispersed in hemorrhage ecchymosis, dimly red tongue, and yellow fur is thick and dry, wiry and frequent pulse, card is to accumulate in pyretic toxicity, stagnant heat resistance network, give one and half courses for the treatment of of this treatment leukemia new drug plus-minus treatment, all diseases completely without, follow up a case by regular visits to without recurrence.
Model case 2: Hu, man, 34 years old, Fauna of Taoyuan, Nw Hunan people.Patient rose and even has said dizziness before one month, thought be at that time nutrition poor due to, because patient vomitted at that time, every meal feed is only one bowl of one bowl of rice water or rice flour paste, does not substantially eat meat, dish; By hospital, find and suffer from acute non-lymphoid leukemia (M2a type), be in hospital.Do not make chemotherapy, plasma transfusion 2 times, raw arteries and veins and ATP five times.Clothes " cleislanthin-B ".Do not feel any better.Seek medical advice upon somebody's introduction.Readme early stage is because of the fever Pei Fusha star of once infusing in a large number, and face is without color, and eye is micro-the blood streak, and color is white now, gingival hemorrhage, and dizziness, myasthenia of limbs has purpura.Take 42 doses of this treatment leukemia new drugs, remission, former side's plus-minus continues to take test rating recovery two courses for the treatment of normally.
Model case 3: Lee, female, 19 years old, Fauna of Taoyuan, Nw Hunan people.Through hospital diagnosis leukemia, be hospitalized for treatment.While seeing a doctor, hair comes off, and whole body many places black speck is that the toxic and side effects that chemotherapy occurs causes, takes this treatment leukemia new drug and after the course for the treatment of, entirely heals more than three, and do manual work in other places now.
Model case 4: Wang, man, 60 years old, Haikou City people.Through the hospital expert diagnosing liver cancer chemotherapy of being admitted to hospital, see a doctor upon somebody's introduction.Disease is seen: hypochondriac pain, gather, jaundice, tympanites, yellow skin is black in pool; According in theory of Chinese medical science < < through > > cloud: " in healthy energy deposits; heresy can not be done; the institute of heresy gathers; its gas must be empty " take that spleen invigorating is regulated the flow of vital energy, invigorating QI and blood, nourishing the liver and kidney Chinese medicine be as main, be aided with this treatment leukemia new drug plus-minus for the methods such as depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, eliminating damp-heat, hard masses softening and resolving, eliminating mass removing mass, nourishing the liver and kidney, suppressing the hyperactive liver to relieve the wind syndrome, entirely heal three courses for the treatment of.
Model case 5: Chen, man, 4 years old half, people from Changsha, was diagnosed as myelodysplastic syndrome through hospital expert, belonged to leukemia symptom in early stage.Now Shanghai hospital does bone marrow and moves and grow secondary, carrys out upon somebody's introduction diagnosis and treatment.Take this treatment leukemia new drug plus-minus, two the course for the treatment of symptom alleviate completely, in anti-.

Claims (2)

1. a new drug for the treatment of leukemia, by conventional Chinese medicine method for making, made, it is characterized in that: this medicine is made by the herbal raw material of following weight parts: Ramulus et folium taxi cuspidatae 3-5 part, Galium spurium L. 4-6 part, xanthorrhiza 2-4 part, Radix Isatidis 1-2 part, Caulis Polygoni Multiflori 0.5-1, Yunnan Rohdea japonica 1-2 part, Fructus Corni 1-3 part, Rhizoma Chuanxiong 1-2 part, Carapax Trionycis 0.5-1, Ganoderma 1-2 part, Herba Hedyotidis Diffusae 1-2 part, Rhizoma Dioscoreae Bulbiferae 0.5-1 part, Herba Solani Lyrati 1-2 part, Cortex Eucommiae 1-1.5 part, Radix Polygoni Multiflori 0.5-1 part, Rhizomadioscoreae 1-1.5 part, Radix Rehmanniae 0.5-1 part, Radix Rehmanniae Preparata 0.5-1 part, Herba Taraxaci 0.5-1 part, Poria cum Radix Pini 0.5-1 part, Fructus Lycii 0.5-1 part, Radix Salviae Miltiorrhizae 0.5-1 part, Herba Violae 0.5-1 part, Herba Scutellariae Barbatae 0.5-1 part, Fructus Ligustri Lucidi 0.5-1 part, Semen Cuscutae 0.5-1 part, Rhizoma Sparganii 0.5-1 part, Rhizoma Curcumae 0.5-1 part, Radix Angelicae Sinensis 0.1-0.5 part, Flos Carthami 0.5-1 part, Rhizoma Polygonati 0.1-0.5 part, Radix Dipsaci 0.1-0.5 part, Radix Ginseng Rubra 0.01-0.05 part, Radix Ginseng 0.1-0.5 part, Fructus Schisandrae Chinensis 0.1-0.5 part, Radix Glycyrrhizae 0.1-0.5 part, Indigo Naturalis 0.1-0.5 part, Realgar 0.01-0.05 part, totally 38 taste medicines.
2. the new drug for the treatment of leukemia according to claim 1, it is characterized in that: it is made by the herbal raw material of following weight parts: 3 parts of Ramulus et folium taxi cuspidatae, 4 parts of Galium spurium L.s, 1 part of Radix Ginseng, 2 parts of xanthorrhizas, 1 part of Radix Isatidis, 0.5 part of Caulis Polygoni Multiflori, 1 part of Yunnan Rohdea japonica, 1 part of Fructus Corni, 1 part of Rhizoma Chuanxiong, 0.5 part of Carapax Trionycis; 1 part of Ganoderma, 1 part of Herba Hedyotidis Diffusae, 0.5 part of Rhizoma Dioscoreae Bulbiferae, 1 part of Herba Solani Lyrati, 1 part of the Cortex Eucommiae, 0.5 part of Radix Polygoni Multiflori, 1 part of Rhizomadioscoreae, 0.5 part, the Radix Rehmanniae, 0.5 part, Radix Rehmanniae Preparata, 0.5 part of Herba Taraxaci, 0.5 part of Poria cum Radix Pini, 0.5 part of Fructus Lycii, 0.5 part of Radix Salviae Miltiorrhizae, 0.5 part of Herba Violae, 0.5 part of Herba Scutellariae Barbatae, 0.5 part of Fructus Ligustri Lucidi, 0.5 part of Semen Cuscutae, 0.5 part of Rhizoma Sparganii, 0.5 part of Rhizoma Curcumae, 0.1 part of Radix Angelicae Sinensis, 0.1 part, Flos Carthami, 0.1 part of Rhizoma Polygonati, 0.1 part of Radix Dipsaci, 0.01 part of Radix Ginseng Rubra, 0.1 part of Fructus Schisandrae Chinensis, 0.1 part, Radix Glycyrrhizae, 0.1 part of Indigo Naturalis, 0.01 part of Realgar, totally 38 taste Chinese medicines.
3. the new drug for the treatment of leukemia according to claim 1, it is characterized in that: it is made by the herbal raw material of following weight parts: 5 parts of Ramulus et folium taxi cuspidatae, 6 parts of Galium spurium L.s, 2 parts of Radix Ginseng, 4 parts of xanthorrhizas, 2 parts of Radix Isatidis, 1 part of Caulis Polygoni Multiflori, 2 parts of Yunnan Rohdea japonica, 3 parts of Fructus Cornis, 2 parts of Rhizoma Chuanxiongs, 1 part of Carapax Trionycis; 2 parts of Ganodermas, 1 part of Herba Hedyotidis Diffusae, 1 part of Rhizoma Dioscoreae Bulbiferae, 2 parts of Herba Solani Lyratis, 5 parts of the Cortexs Eucommiae, 1 part of Radix Polygoni Multiflori, 1.5 parts of Rhizomadioscoreae, 1 part, the Radix Rehmanniae, 1 part, Radix Rehmanniae Preparata, 1 part of Herba Taraxaci, 1 part of Poria cum Radix Pini, 1 part of Fructus Lycii, 0.5 part of Radix Salviae Miltiorrhizae, 0.5 part of Herba Violae, 1 part of Herba Scutellariae Barbatae, 1 part of Fructus Ligustri Lucidi, 1 part of Semen Cuscutae, 1 part of Rhizoma Sparganii, 1 part of Rhizoma Curcumae, 0.5 part of Radix Angelicae Sinensis, 1 part, Flos Carthami, 0.5 part of Rhizoma Polygonati, 0.5 part of Radix Dipsaci, 0.05 part of Radix Ginseng Rubra, 0.5 part of Fructus Schisandrae Chinensis, 0.5 part, Radix Glycyrrhizae, 0.5 part of Indigo Naturalis, 0.05 part of Realgar, totally 38 taste Chinese medicines.
CN201210094444.7A 2012-04-01 2012-04-01 New medicament for treating leukemia Expired - Fee Related CN102631518B (en)

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