CN102600239A - Medicament for treating thromboangitis obliterans and preparation method thereof - Google Patents

Abstract

The invention discloses a medicament for treating thromboangitis obliterans, which is formed by mixing, crushing and grinding the following components in weight parts: astragalus mongholicus, honeysuckle, Chinese angelica, leech, centipede, bombys batryticatus, earthworm, roasted liquorice, roasted frankincense, myrrh, ground beetle, scorpion, radix salviae miltiorrhizae, hemlock parsley, roasted nux vomica and cassia twig. The medicament has the functions of reinforcing qi and nourishing blood, removing cold-dampness, activating blood circulation to remove stasis, regulating meridians, supporting healthy energy, and removing blood stasis to promote tissue regeneration, and is used for treating vital energy and blood circulation obstruction caused by weak, cold and damp spleen and kidney, venation stasis, and vasculitis at tail ends of four limbs or caused by fire heat generation and yin impairment due to damp stagnation. The medicament has remarkable effect to each phase of the vasculitis, has good treatment effect to deep venous thrombosis, phlebophlogosis and other peripheral vascular diseases, and has high cure rate, quick response, stable curative effect and relapse prevention.

Description

Medicine of treatment thromboangiitis obliterans and preparation method thereof

Technical field

The present invention relates to field of traditional Chinese, specifically be meant a kind of medicine of treating thromboangiitis obliterans and preparation method thereof.

Background technology

Its disease of thromboangiitis obliterans is a kind of evil cellulitis property disease, and this less patient suffering can't bear, and has a delicate constitution, many death because malpractice develops complications.The Chinese medicine and western medicine of treatment thromboangiitis obliterans is more at present, but exists curative effect slower, needs the regular hour, and perhaps therapeutic effect is not good, and the defective that is difficult to effect a radical cure.

Summary of the invention

The objective of the invention is provides a kind of rapid-action for the deficiency that overcomes prior art, effective, and the medicine of the treatment thromboangiitis obliterans that cure rate is high provides a kind of method for preparing of this medicine simultaneously.

For realizing that the technical scheme that above-mentioned purpose provides is:

A kind of medicine of treating thromboangiitis obliterans, mix back pulverizing pulverize by weight by following raw materials according and form:

Radix Astragali 25-30 Flos Lonicerae 50-60 Radix Angelicae Sinensis 15-20 Hirudo 45-50

Scolopendra 10-15 Bombyx Batryticatus 5-10 Pheretima 35-45 Radix Glycyrrhizae Preparata 10-15

Moxibustion Olibanum 15-25 Myrrha 15-25 Eupolyphaga Seu Steleophaga 15-25 Scorpio 15-25

Radix Salviae Miltiorrhizae 25-30 Rhizoma Chuanxiong 15-25 moxibustion Semen Strychni 15-20 Ramulus Cinnamomi 15-20.

A kind of method for preparing of medicine of above-mentioned treatment thromboangiitis obliterans is made up of the following step:

A, powder process: get the Radix Astragali, Flos Lonicerae, Radix Angelicae Sinensis, Hirudo, Scolopendra, Bombyx Batryticatus, Pheretima, Radix Glycyrrhizae Preparata, moxibustion Olibanum, Myrrha 、 Eupolyphaga Seu Steleophaga, Scorpio, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, moxibustion Semen Strychni, Ramulus Cinnamomi by weight, mix back pulverizing, porphyrize powder, for use;

B, preparation: above-mentioned fine powder is stirred, incapsulate.

Thromboangiitis obliterans belongs to a kind of middle small artery and the chronic nonsuppurative inflammation of venous, is a kind of evil cellulitis property disease.The traditional Chinese medical science thinks that necrosis can be divided into for three phases: ischemia phase, malnutrition phase, downright bad phase; In primary disease is main because spleen suffers from a deficiency of the kidney, outer because cold-damp, internal and external reasons combines to cause that QI and blood is obstructed, venation is retarded by silt, can not the nutrition limb end or damp-stagnancy heat-transformation impairment of YIN due to.To this cause of disease, oral this invention medication, disease and select medicine in view of the above.Medicine astragalus, angelica, licorice has qi, solid form, Huoxuetongluo, diuretic, detoxifying, spleen Yang Qi, phlegm, cough, urgency and analgesic efficacy, coupled with leeches to be blood stasis, meridians; plus scorpion, centipede, earthworm has Xifeng analgesic, attack drug relieves congestion, heat the frightened, meridians, carminative effect; tie Strychnos, purple salvia, frankincense, myrrh and eradicates stasis pain, circulation and relief swelling, Qingxin Chufan; honeysuckle has heat, detoxification, cool wind-heat effect; so that the drug directly to lesions, played treating the symptoms, immediate, quickly relieve symptoms.These Drug therapy characteristics are: act on rapid, rapid-action; Patient is prone to accept, and is evident in efficacy, characteristics such as cure rate height.And stable curative effect is difficult for recurrence, and raw material is prone to obtain, and has no side effect.

In summary, the present invention is to blood stasis, tongmai, but also pain, inflammation, swelling, up blood, to tackling the problem of the effect, the present invention has the BNI, eradicates alpine addiction, blood stasis, mediation meridians, righting, the effect of new students to silt.Treatment is because spleen, kidney, void, the QI and blood due to cold, wet are obstructed, the vasculitis due to venation stasis, limb end or the damp-stagnancy heat-transformation impairment of YIN.Comprise: I, II, the various symptoms of III stage angiitis all have unique therapeutic effect; Angiopathy around DVT, the phlebitis etc. is also had good therapeutic effect, and cure rate is high.

Treatment thromboangiitis obliterans thing method for using of the present invention: " 0 " number capsule that medicine is packed into, each oral five sooner or later.

Come further to set forth beneficial effect of the present invention through the clinical observation on the therapeutic effect experiment below.

This clinical experiment 100 examples meet the thromboangiitis obliterans patient of Western medicine diagnose standard, all derive from clinic case, age 25-84 year, male's 60 examples wherein, women's 40 examples; Age 25-40 year 40 examples, age 41-84 year 60 examples.

Therapeutic Method: each 5 3.0 grams of oral medicine of the present invention, every day 2 times, one month is the course of treatment, is total to the 2-5 course of treatment.

Curative effect determinate standard: with symptom change degree is curative effect determinate standard.

Observed result: clinical cure 80 examples, effective 15 examples, invalid 5 examples, cure rate 80%, aggregate efficiency 95%.Only have 5 examples invalid in the treatment, all cases all have no adverse reaction.To clinical cure personnel random inspection 20 people, follow up a case by regular visits to and do not see recurrence in 2 years.

See 4 routine cases for details:

Case 1: Li Guiyong, man, 60 years old, Jilin Dunhua peasant.This patient suffered from vasculitis through the how tame hospitalize commentaries on classics of not getting better in 2010, come the court to go to a doctor on April 5th, 2011, had a medical check-up: painful sickly complexion, and right lower extremity is sent out cold; Fear of cold, numbness, and intermittent claudication and foot pain are arranged, femoral pulse is normal, and dorsal artery of foot does not have beats; Be diagnosed as the vasculitis I phase, behind oral this medicine the 3rd day, symptom was alleviated gradually; Transference cure after one course of treatment continues oral this medicine to second course of treatment, to consolidate curative effect.Return to one's perfect health, emotion is optimistic at present.

Case 2: Zhang Chengguo, man, 39 years old, Muling City, Heilongjiang Province peasant.Because of having a pain in the leg, a left side come my institute to go to a doctor on February 4th, 2010 bitterly; Main suit: a large amount of smoking histories are arranged; Have a medical check-up: body constitution is become thin, complexion is dark yellow; BP:100mmHG/60mmHG; P:100 time/minute; Left side lower limb big toe cyanosis of the skin, middle toe skin rubefaction and rest pain, with night for very, raise the trouble limb, palor, no instep arteriopalmus is diagnosed as the vasculitis II phase; 1 course of treatment of oral this medicine+dead point MAILUONING 40ml, one week the back symptom take a turn for the better, but out-of-bed activity, the acid sx that expands serve on 2 courses of treatment of this medicine, clinical cure, local blood supply improves, and can normally do manual work.

Case 3: Sun Xingwang, man, 63 years old, Weifang City, Shandong; Can not be engaged in physical work, multi-treatment, poor effect because of suffering from vasculitis for many years in 2009.Come me institute to go to a doctor on March 17th, 2010; Main suit: diabetic history is arranged 20 years, a large amount of smoking histories 30 years; Have a medical check-up: right lower limb is red, swollen, hot, pain obviously, the necrosis of festering of big toe tip; The T:38.5 degree; BP:120mmHG/70mmHG; Left side lower limb is sent out cold, is afraid of cold, paroxysmal pain, is diagnosed as the vasculitis III phase; Right lower limb forms gangrene, rancid, pain unbearably because of secondary infection; Therapeutic scheme (1): oral this invention medicine; (2): 0.9% saline+penicillin 1,800 ten thousand+DIMI 10mg dead points; D-6; (3) 0.9% saline+MAILUONING 50mg dead point; D-6; (4) external autogamy external application of ointment, debridement face is gone up anti-inflammatory ointment outward, and symptom was controlled in the 3rd day; Three courses of treatment of this medicine of continuous oral, doing well,improving; The gangrene part comes off, left lower limb transference cure, and set up side and prop up blood circulation, improved local blood supply insufficiency symptom, avoided the hardship of amputation.The patient is emotionally stable, mental status is good, the life of taking care of oneself, dried work in power.

Case 4: Ma Shuzhen, the woman, 71 years old, Dunhua yellow mud river, Jilin peasant, I go to a doctor at institute February for, pain cool because of human hair combing waste on January 3rd, 2009; Look into: body constitution is become thin, chronic facies, right lower limb limitation of activity, paroxysmal pain, cool, sour expanding; Diagnosis: vasculitis I phase.Treatment: 2 courses of treatment of oral this medicine, advise patient to strengthen nutrition, function of spleen and stomach regulating, doing well,improving; The discontinuity medication is taken care of oneself so far at present, clinical cure.

The specific embodiment

Embodiment 1

A kind of medicine of treating thromboangiitis obliterans is made up of following traditional Chinese medicine raw:

Radix Astragali 25g Flos Lonicerae 50g Radix Angelicae Sinensis 15g Hirudo 45 g

Scolopendra 10g Bombyx Batryticatus 5g Pheretima 35 g Radix Glycyrrhizae Preparata 10g

Moxibustion Olibanum 15g Myrrha 15g Eupolyphaga Seu Steleophaga 15g Scorpio 15 g

Radix Salviae Miltiorrhizae 25 g Rhizoma Chuanxiong 15g moxibustion Semen Strychni 15g Ramulus Cinnamomi 15g

Method for preparing:

A, powder process: with the Radix Astragali, Flos Lonicerae, Radix Angelicae Sinensis, Hirudo, Scolopendra, Bombyx Batryticatus, Pheretima, Radix Glycyrrhizae Preparata, moxibustion Olibanum, Myrrha 、 Eupolyphaga Seu Steleophaga, Scorpio, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, moxibustion Semen Strychni, Ramulus Cinnamomi, mix back pulverizing, porphyrize powder, for use;

B, preparation: above-mentioned fine powder is stirred, cross 220 mesh sieves, " 0 " capsule of packing into.

Embodiment 2

A kind of medicine of treating thromboangiitis obliterans is made up of following traditional Chinese medicine raw:

Radix Astragali 30g Flos Lonicerae 60g Radix Angelicae Sinensis 20g Hirudo 50g

Scolopendra 15g Bombyx Batryticatus 10g Pheretima 45g Radix Glycyrrhizae Preparata 15g

Moxibustion Olibanum 25g Myrrha 25g Eupolyphaga Seu Steleophaga 25g Scorpio 25g

Radix Salviae Miltiorrhizae 30g Rhizoma Chuanxiong 25g moxibustion Semen Strychni 20g Ramulus Cinnamomi 20g

Its preparation method is with embodiment 1.

Embodiment 3

Radix Astragali 30g Flos Lonicerae 50g Radix Angelicae Sinensis 20g Hirudo 50g

Scolopendra 10g Bombyx Batryticatus 5g Pheretima 45g Radix Glycyrrhizae Preparata 10g

Moxibustion Olibanum 20g Myrrha 20g Eupolyphaga Seu Steleophaga 20g Scorpio 20g

Radix Salviae Miltiorrhizae 30g Rhizoma Chuanxiong 20g moxibustion Semen Strychni 15g Ramulus Cinnamomi 15g

Its preparation method is with embodiment 1.

Claims (2)

1. medicine of treating thromboangiitis obliterans is characterized in that mixing the back by weight by following raw materials according pulverizes pulverize and form:

Radix Astragali 25-30 Flos Lonicerae 50-60 Radix Angelicae Sinensis 15-20 Hirudo 45-50

Scolopendra 10-15 Bombyx Batryticatus 5-10 Pheretima 35-45 Radix Glycyrrhizae Preparata 10-15

Moxibustion Olibanum 15-25 Myrrha 15-25 Eupolyphaga Seu Steleophaga 15-25 Scorpio 15-25

Radix Salviae Miltiorrhizae 25-30 Rhizoma Chuanxiong 15-25 moxibustion Semen Strychni 15-20 Ramulus Cinnamomi 15-20.

2. the method for preparing of the medicine of a treatment thromboangiitis obliterans as claimed in claim 1 is made up of the following step:

A, powder process: get the Radix Astragali, Flos Lonicerae, Radix Angelicae Sinensis, Hirudo, Scolopendra, Bombyx Batryticatus, Pheretima, Radix Glycyrrhizae Preparata, moxibustion Olibanum, Myrrha 、 Eupolyphaga Seu Steleophaga, Scorpio, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, moxibustion Semen Strychni, Ramulus Cinnamomi by weight, mix back pulverizing, porphyrize powder, for use;

B, preparation: above-mentioned fine powder is stirred, incapsulate.