CN104288612A - Traditional Chinese medicine preparation for treating diabetes gangrene symptom - Google Patents
Traditional Chinese medicine preparation for treating diabetes gangrene symptom Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating a diabetes gangrene symptom. The traditional Chinese medicine preparation comprises membranous milkvetch root, dendrobe, Chinese angelica, achyranthes bidentata, leech, honeysuckle stem, red paeony root, safflower, lumbricus, phaseolus calcaratus, prepared frankincense, chinese starjasmine stem, homalomena occulta, hematoxylon, the seed of Job's tears, cortex phellodendri, and motherwort herb. The traditional Chinese medicine preparation provided by the invention has the efficacies of detoxifying, relieving pain, reducing swelling, promoting diuresis, detoxifying and dispersing blood stasis; after a patient takes the traditional Chinese medicine preparation, the infection can be controlled rapidly, the protein metabolism can be slowed down, the synthesis of the immune complex can be reduced, the vessel wall can be repaired, the microcirculation can be regulated, the blood vessel can be expanded, the oxygen uptake of the vascular tissue can be promoted, and the lumen stenosis or blockage of the aortas of lower limbs can be suppressed; meanwhile, the peripheral nerve dysfunction can be removed, the growth of the fibrocyte can be promoted, the healing of the trauma can be accelerated, the blood circulation system, the secretion system, the digestive system and the like are enabled to recover the self-regulation function, the symptoms of easiness in infection, swelling, pain, lower limb weakness and the like can be relieved completely, and the aim for curing the diabetes gangrene symptom can be realized.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating diabetic gangrene disease.
Background technology
Diabetic gangrene disease is one of the most common and the most serious chronic complicating diseases of diabetes, refers to concurrent infection human body of losing consciousness because of neuropathy and lose vigor because of ischemia.Diabetic gangrene disease betides middle-aged and elderly people mostly, and after being mainly in 50 years old, how common 60-70 year is.Male more than female, diabetic duration on average about 10 years, gangrenous position lower limb are common; One-sided morbidity is fallen ill higher than bilateral simultaneously; The while of toes and vola, gangrene is common.Be more common in obesity or adult and the long diabetics of the course of disease, on average about 10 years.Gangrene can occur suddenly, sharp ache, most of patients gangrene be slowly, have serious nervous lesion, critical limb brothers are festered necrosis, withered blackening, suppurative infection etc.Diabetic acromelic gangrene Clinical types has dry gangrene, wet gangrene, mixed type gangrene three kinds.Clinical main manifestations symptom is the symptoms such as lower limb are weak, numb, pain, intermittent claudication.
At present, modern medicine mainly adopts anticoagulant, thrombolytic, infection and the method such as to have an operation is treated.But therapeutic effect is not very desirable, and most of patients is by amputation, and side effect is large, relapse rate is high.Therefore provide a kind of in case amputation, rapid-action, that relapse rate is low Therapeutic Method are inexorable trends.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides the Chinese medicine preparation of the treatment diabetic gangrene disease that a kind of cure rate is high, rapid-action, relapse rate is low.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for diabetic gangrene disease, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Astragali 20-30 gram, Herba Dendrobii 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Radix Achyranthis Bidentatae 10-20 gram, Hirudo 10-20 gram, Caulis Lonicerae 8-15 gram, Radix Paeoniae Rubra 8-15 gram, Flos Carthami 8-15 gram, Pheretima 6-10 gram, Semen Phaseoli 6-10 gram, Olibanum (processed) 6-10 gram, Caulis Trachelospermi 6-10 gram, Rhizoma Homalomenae 6-10 gram, Lignum Sappan 6-10 gram, Semen Coicis 6-10 gram, Cortex Phellodendri 6-10 gram, Herba Leonuri 6-10 gram.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 20 grams, Herba Dendrobii 10 grams, Radix Angelicae Sinensis 10 grams, Radix Achyranthis Bidentatae 10 grams, Hirudo 10 grams, Caulis Lonicerae 8 grams, Radix Paeoniae Rubra 8 grams, 8 grams, Flos Carthami, Pheretima 6 grams, Semen Phaseoli 6 grams, Olibanum (processed) 6 grams, Caulis Trachelospermi 6 grams, Rhizoma Homalomenae 6 grams, Lignum Sappan 6 grams, Semen Coicis 6 grams, Cortex Phellodendri 6 grams, Herba Leonuri 6 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 30 grams, Herba Dendrobii 20 grams, Radix Angelicae Sinensis 20 grams, Radix Achyranthis Bidentatae 20 grams, Hirudo 20 grams, Caulis Lonicerae 15 grams, Radix Paeoniae Rubra 15 grams, 15 grams, Flos Carthami, Pheretima 10 grams, Semen Phaseoli 10 grams, Olibanum (processed) 10 grams, Caulis Trachelospermi 10 grams, Rhizoma Homalomenae 10 grams, Lignum Sappan 10 grams, Semen Coicis 10 grams, Cortex Phellodendri 10 grams, Herba Leonuri 10 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 25 grams, Herba Dendrobii 15 grams, Radix Angelicae Sinensis 15 grams, Radix Achyranthis Bidentatae 15 grams, Hirudo 15 grams, Caulis Lonicerae 12 grams, Radix Paeoniae Rubra 12 grams, 12 grams, Flos Carthami, Pheretima 8 grams, Semen Phaseoli 8 grams, Olibanum (processed) 8 grams, Caulis Trachelospermi 8 grams, Rhizoma Homalomenae 8 grams, Lignum Sappan 8 grams, Semen Coicis 8 grams, Cortex Phellodendri 8 grams, Herba Leonuri 8 grams.
Wherein:
Radix Astragali sweet in the mouth, slightly warm in nature, returns lung, spleen, liver, kidney channel, has effect that QI invigorating, QI invigorating, invigorating middle warmer, consolidating superficial resistance, arresting sweating are admittedly de-, hold in the palm skin ulcer, granulation promoting, diuretic, detumescence.Primaryly be used for the treatment of exterior deficiency spontaneous perspiration, carbuncle difficulty burst, burst for a long time do not hold back, the treatment of the symptom such as blood deficiency and yellow complexion, interior-heat are quenched one's thirst, albuminuria, diabetes.
Herba Dendrobii sweet in the mouth, cold nature, returns stomach, kidney channel, has QI invigorating, promotes the production of body fluid, YIN nourishing, heat clearing away, the effect such as to moisturize.Herba Dendrobii is exactly the medicine dedicated for the treatment of diabetes since ancient times.Clinical research shows, Herba Dendrobii not only can strengthen insulin active, significantly can reduce blood sugar level simultaneously, make blood sugar recovery normal.Herba Dendrobii can improve stress ability, has good resisting fatigue, resisting oxygen lack, can promote circulation, blood vessel dilating, reduction cholesterolemia and triglyceride.
Radix Angelicae Sinensis bitter in the mouth, warm in nature, return liver, the heart, spleen channel, have and enrich blood, invigorate blood circulation, pain relieving, the effect such as to moisturize.
Radix Achyranthis Bidentatae sour in the mouth, property is put down, return liver, kidney channel, there is tonifying liver, kidney tonifying, invigorate blood circulation, blood stasis dispelling, dredging collateral, the effect such as logical urine, pain relieving.Be usually used in symptom such as treatment soreness of waist and knee joint, flaccidity and weakness of the lower limbs etc.
Hirudo salty in the mouth, property is put down, and returns Liver Channel, has the effects such as removing blood stasis, blood stasis dispelling, detumescence.
Caulis Lonicerae sweet in the mouth, cold in nature, attach to the lung and stomach meridians, there is the effects such as heat clearing away, removing toxic substances, dredging collateral, QI invigorating, antiinflammatory.
Radix Paeoniae Rubra bitter in the mouth, cold nature, returns Liver Channel, has the effects such as clots absorbing, pain relieving, removing heat from blood, detumescence, QI invigorating, dredging collateral.
Flos Carthami acrid in the mouth, warm in nature, GUIXIN, Liver Channel, have invigorate blood circulation, blood stasis dispelling, dredging collateral, the effect such as pain relieving.
Pheretima salty in the mouth, cold in nature, return liver, spleen, urinary bladder channel, there is the effects such as heat clearing away, pain relieving, dredging collateral, diuresis.
Semen Phaseoli sweet in the mouth, property is put down, return spleen, the heart, lung, small intestine meridian, there is dampness removing, to disappear kind, removing toxic substances, the effect such as evacuation of pus.There is the effect regulating blood glucose, be usually used in the treatment at the initial stage of diabetic gangrene disease.
Olibanum (processed) bitter in the mouth, slightly warm in nature, GUIXIN, liver, spleen channel, have invigorate blood circulation, pain relieving, QI invigorating, removing toxic substances, detumescence, the effect such as dredging collateral.
Caulis Trachelospermi bitter in the mouth, cold nature, GUIXIN, liver, kidney channel, there is dampness removing, dredging collateral, pain relieving, invigorate blood circulation, removing heat from blood, removing toxic substances, the effect such as detumescence.
Rhizoma Homalomenae bitter in the mouth, warm in nature, return liver, kidney, stomach warp, there is the effects such as dampness removing, active, relaxing muscles and tendons, pain relieving, detumescence.
Lignum Sappan sweet in the mouth, cool in nature, GUIXIN, liver, stomach, spleen channel, have invigorate blood circulation, blood stasis dispelling, detumescence, pain relieving, the effect such as dredging collateral.
Semen Coicis sweet in the mouth, cold nature, returns spleen, stomach, lung meridian, there is dampness removing, numbness of dispelling, heat clearing away, the effect such as evacuation of pus.
Cortex Phellodendri bitter in the mouth, cold in nature, return kidney, bladder, large intestine channel, there is the effects such as heat clearing away, removing toxic substances, dampness, treatment skin ulcer.
Herba Leonuri and Herba Leonuri, bitter in the mouth, cold in nature, GUIXIN, liver,spleen,kidney, urinary bladder channel, have invigorate blood circulation, blood stasis dispelling, dredging collateral, detumescence, dampness removing, removing blood stasis, the effect such as removing toxic substances.The symptom such as sore and toxic, urticaria can be treated.
Between every taste Chinese medicine in the present invention, by drawing after several clinical formulation 5, its manufacture method is simple, can be made into the dosage forms such as tablet, pill, powder or oral liquid as required, Chinese medicine preparation of the present invention has the effects such as removing toxic substances, pain relieving, detumescence, dampness removing, poison holding, removing toxic substances, blood stasis dispelling.
After taking, rapid infection control, can slow down Proteometabolism, reduces the synthesis of immune complex, repairs blood vessel wall, regulates microcirculation, blood vessel dilating, promotes that vascular tissue is to oxygen absorption, suppresses luminal stenosis or the obstruction of lower limb trunk; Remove peripheral nerve dysfunction, promote fibrocellular growth, accelerate the healing of wound face, blood circulation, excretory system, digestive system etc. are made to recover the function of self regulation, the symptoms such as thorough releasing easy infection, swelling, pain, lower limb are weak, realize the object of curing diabetic gangrene disease.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, one after each meal, a month sky is a course for the treatment of.
The present invention is according to the pharmacology of above-mentioned Chinese medicine, and clinical trial for several times, to blue or green, in, old Different age group light, in, the gangrenous disease patient of severe diabetic all has obvious antihypertensive effect.
For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected the treatment curative effect of 132 routine diabetic gangrene disease patients to medicine of the present invention and carry out clinical trial.Wherein male 82, women 50 example, 4 examples at less than 40 years old age, 41 ~ 50 years old 12 example, 51 ~ 60 years old 40 example, 61 ~ 70 years old 60 example, 16 examples of more than 70 years old.58 years old mean age.
Criterion of therapeutical effect:
Cure: clinical symptom disappearance, wound healing;
Effective: clinical symptoms is clearly better, wound healing;
Effective: clinical symptoms takes a turn for the better, and the wound state of an illness is effectively controlled;
Invalid: clinical symptoms is not any change.
After patient takes three courses for the treatment of of rear Chinese medicine preparation of the present invention, 108 examples are cured, and account for 81.8%, and effective 20 examples, account for 15.1%, and effective 3 examples, account for 2.3%, and total effective rate 131 example, accounts for 99.2%, invalid 1 example.Can find out that Chinese medicine preparation therapeutic effect of the present invention is remarkable, cure rate is high, and side effect is little, just can cure without amputation, obtains the consistent favorable comment of extensive patients and family members.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of diabetic gangrene disease, described Chinese medicine preparation is made up of the Radix Astragali 20 grams, Herba Dendrobii 10 grams, Radix Angelicae Sinensis 10 grams, Radix Achyranthis Bidentatae 10 grams, Hirudo 10 grams, Caulis Lonicerae 8 grams, Radix Paeoniae Rubra 8 grams, 8 grams, Flos Carthami, Pheretima 6 grams, Semen Phaseoli 6 grams, Olibanum (processed) 6 grams, Caulis Trachelospermi 6 grams, Rhizoma Homalomenae 6 grams, Lignum Sappan 6 grams, Semen Coicis 6 grams, Cortex Phellodendri 6 grams, Herba Leonuri 6 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, three times on the one, one after each meal, it within one month, is a course for the treatment of, three to five courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of diabetic gangrene disease, described Chinese medicine preparation is made up of the Radix Astragali 30 grams, Herba Dendrobii 20 grams, Radix Angelicae Sinensis 20 grams, Radix Achyranthis Bidentatae 20 grams, Hirudo 20 grams, Caulis Lonicerae 15 grams, Radix Paeoniae Rubra 15 grams, 15 grams, Flos Carthami, Pheretima 10 grams, Semen Phaseoli 10 grams, Olibanum (processed) 10 grams, Caulis Trachelospermi 10 grams, Rhizoma Homalomenae 10 grams, Lignum Sappan 10 grams, Semen Coicis 10 grams, Cortex Phellodendri 10 grams, Herba Leonuri 10 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, three times on the one, one after each meal, it within one month, is a course for the treatment of, three to five courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of diabetic gangrene disease, described Chinese medicine preparation is made up of the Radix Astragali 25 grams, Herba Dendrobii 15 grams, Radix Angelicae Sinensis 15 grams, Radix Achyranthis Bidentatae 15 grams, Hirudo 15 grams, Caulis Lonicerae 12 grams, Radix Paeoniae Rubra 12 grams, 12 grams, Flos Carthami, Pheretima 8 grams, Semen Phaseoli 8 grams, Olibanum (processed) 8 grams, Caulis Trachelospermi 8 grams, Rhizoma Homalomenae 8 grams, Lignum Sappan 8 grams, Semen Coicis 8 grams, Cortex Phellodendri 8 grams, Herba Leonuri 8 grams.
After above-mentioned Chinese herb mixing, decoct with water one hour, elimination medicinal residues, just water decoction for oral use, every day potion, three times on the one, one after each meal, it within one month, is a course for the treatment of, three to five courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Some patients healing case is as follows:
Zhao XX, man, 72 years old, suffers from diabetes recent two decades, time medical, the biped colour of skin is dim, the purple black existing ulceration of biped little toe, and biped back of the body arterial pulse is more weak, after taking a course for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and fully recovers after continuing to take two courses for the treatment of, after follow up a case by regular visits to without recurrence.
Chapter XX, man, 69 years old, suffer from diabetes and have a surplus for 10 years, time medical, the blackening of double-legged instep skin, analgesis, skin histology started necrosis of festering, and after taking Chinese medicine preparation of the present invention two, symptom is clearly better, and fully recovers after continuing to take three courses for the treatment of.
Lee XX, female, 59 years old, the left foot back of the body was red and swollen, and toe skin turns black, and lower limb are weak, and take Chinese medicine preparation of the present invention after one month, symptom obviously alleviates, and continued to take after two months and fully recovered.
Claims (4)
1. treat a Chinese medicine preparation for diabetic gangrene disease, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Astragali 20-30 gram, Herba Dendrobii 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Radix Achyranthis Bidentatae 10-20 gram, Hirudo 10-20 gram, Caulis Lonicerae 8-15 gram, Radix Paeoniae Rubra 8-15 gram, Flos Carthami 8-15 gram, Pheretima 6-10 gram, Semen Phaseoli 6-10 gram, Olibanum (processed) 6-10 gram, Caulis Trachelospermi 6-10 gram, Rhizoma Homalomenae 6-10 gram, Lignum Sappan 6-10 gram, Semen Coicis 6-10 gram, Cortex Phellodendri 6-10 gram, Herba Leonuri 6-10 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 20 grams, Herba Dendrobii 10 grams, Radix Angelicae Sinensis 10 grams, Radix Achyranthis Bidentatae 10 grams, Hirudo 10 grams, Caulis Lonicerae 8 grams, Radix Paeoniae Rubra 8 grams, 8 grams, Flos Carthami, Pheretima 6 grams, Semen Phaseoli 6 grams, Olibanum (processed) 6 grams, Caulis Trachelospermi 6 grams, Rhizoma Homalomenae 6 grams, Lignum Sappan 6 grams, Semen Coicis 6 grams, Cortex Phellodendri 6 grams, Herba Leonuri 6 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 30 grams, Herba Dendrobii 20 grams, Radix Angelicae Sinensis 20 grams, Radix Achyranthis Bidentatae 20 grams, Hirudo 20 grams, Caulis Lonicerae 15 grams, Radix Paeoniae Rubra 15 grams, 15 grams, Flos Carthami, Pheretima 10 grams, Semen Phaseoli 10 grams, Olibanum (processed) 10 grams, Caulis Trachelospermi 10 grams, Rhizoma Homalomenae 10 grams, Lignum Sappan 10 grams, Semen Coicis 10 grams, Cortex Phellodendri 10 grams, Herba Leonuri 10 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that: described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
The Radix Astragali 25 grams, Herba Dendrobii 15 grams, Radix Angelicae Sinensis 15 grams, Radix Achyranthis Bidentatae 15 grams, Hirudo 15 grams, Caulis Lonicerae 12 grams, Radix Paeoniae Rubra 12 grams, 12 grams, Flos Carthami, Pheretima 8 grams, Semen Phaseoli 8 grams, Olibanum (processed) 8 grams, Caulis Trachelospermi 8 grams, Rhizoma Homalomenae 8 grams, Lignum Sappan 8 grams, Semen Coicis 8 grams, Cortex Phellodendri 8 grams, Herba Leonuri 8 grams.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410605682.9A CN104288612A (en) | 2014-10-31 | 2014-10-31 | Traditional Chinese medicine preparation for treating diabetes gangrene symptom |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410605682.9A CN104288612A (en) | 2014-10-31 | 2014-10-31 | Traditional Chinese medicine preparation for treating diabetes gangrene symptom |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620521A (en) * | 2016-12-16 | 2017-05-10 | 姜方迪 | Aerosol capable of nourishing blood, eliminating dampness, removing blood stasis and dredging collaterals |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1788766A (en) * | 2004-12-13 | 2006-06-21 | 河北省中医药研究院高血压糖尿病研究所 | Oral Chinese traditional medicine for treating diabetes foot |
-
2014
- 2014-10-31 CN CN201410605682.9A patent/CN104288612A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1788766A (en) * | 2004-12-13 | 2006-06-21 | 河北省中医药研究院高血压糖尿病研究所 | Oral Chinese traditional medicine for treating diabetes foot |
Non-Patent Citations (1)
| Title |
|---|
| 张冰主编: "《临床中药学》", 30 September 2012, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106620521A (en) * | 2016-12-16 | 2017-05-10 | 姜方迪 | Aerosol capable of nourishing blood, eliminating dampness, removing blood stasis and dredging collaterals |
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Application publication date: 20150121 |