CN1724031A - Medicine for treating rhomboembolia type angiitis - Google Patents

Medicine for treating rhomboembolia type angiitis Download PDF

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CN1724031A
CN1724031A CN 200510017677 CN200510017677A CN1724031A CN 1724031 A CN1724031 A CN 1724031A CN 200510017677 CN200510017677 CN 200510017677 CN 200510017677 A CN200510017677 A CN 200510017677A CN 1724031 A CN1724031 A CN 1724031A
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parts
radix
medicine
treatment
thromboangiitis obliterans
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CN1299723C (en
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毛顺卿
毛振达
毛新慧
卢小红
毛宏
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毛顺卿
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Abstract

A Chinese medicine in the form of powder for treating thromboangiitis terectomy is prepared from 8 Chinese-medicinal materials including Chinese angelica root, cinnamon twigs, astragalus root, ginseng, etc through freeze-drying 2 of them, baking others, grinding and sieving.

Description

The medicine of treatment thromboangiitis obliterans
One. technical field: the present invention relates to a kind of is the medicine of raw material with the natural Chinese medicine, particularly relates to a kind of medicine for the treatment of thromboangiitis obliterans.
Two. background technology: thromboangiitis obliterans is a kind of chronic general vascular disorder, pathological changes involve extremity in, small-sized arteriovenous is seen so that lower limb more more, motherland's medical science thinks that primary disease is sick mainly to be because feelings will internal injury admittedly, kidney liver deficiency, cold-damp is subjected to outward, so that cold-damp cohesion meridians, the numbness plug is obstructed, and vim and vigour running is not smooth, and lumen of vessels takes place inaccessible, the tube wall fibrosis, cause the local organization ischemia, last necrosis causes acral coming off, and cold stimulation is the key factor that primary disease takes place, extremity are the end of all sun, get yang-energy and temperature, the place is cold for a long time, and the cold-evil compels outward, yang-energy can not reach in limb end, cause the cold-evil to attack channels deeply, QI and blood is not smooth, and blood is met cold coagulation, it is obstructed to be retarded by silt, stagnation of QI and blood may bring about pain, with the passing of time, limbs are just become homeless foster, cause gangrene, thereby claim " necrosis disease " again; In addition, the generation of primary disease is also relevant with factors such as long-term smoking, wounds, and under the long-time stimulus of these factors, central nervous system's adjusting is hindered, the autonomic nerve system hormonal system functional disorder (as suprarenalism) of unifying, can make slow blood flow, medium and small continuous vessel spasm, blood vessel wall malnutrition, thrombosis and lumen of vessels obturation, local organization ischemia, necrosis, come off, secondary infection makes that the pain increased.
At present, this disease still there is not satisfied treatment measure both at home and abroad, doctor trained in Western medicine adopts the treatment of blood vessel dilating medicine more, and this type of therapy has certain curative effect to I, II phase patient, but to III phase severe infections patient, adopt potent analgesic to cooperate antibiotic therapy, the person of failing to respond to any medical treatment or end-stage patients' extremity gangrene adopts the amputation that cuts toe or Different Plane, and this operative therapy patient not only will bear huge misery, from then on the more important thing is becomes deformity, has increased burden for family and society.The traditional Chinese medical science Therapeutic Method that adopt based on activating blood circulation to dissipate blood stasis more, as TAOREN SIWU TANG, SIMIAOYONGAN TANG, RENSHEN YANGRONG TANG, attached osmanthus eight flavor balls, ZHIBAI DIHUANG WAN etc., according to the treatment of state of an illness plus-minus, the effect of this Therapeutic Method obviously is better than western medical treatment, but because the complexity of this sick pertinacious disease cause of disease, drug component and consumption unreasonable causes effect still not satisfactory.
Chinese invention patent CN1181868C, application number is 02135295.X, denomination of invention is: in " Chinese medicine preparation of treatment thromboangiitis obliterans ", a kind of Chinese medicine for the treatment of the chronic occlusion inflammation of peripheral vessels is disclosed, it is with Formica fusca, the big gun Squama Manis, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae, Rhizoma Curcumae, Radix Angelicae Sinensis, Fructus Forsythiae, Radix Ilicis Pubescentis, Rhizoma Smilacis Glabrae, 36 kinds of Chinese medicines such as the Rhizoma Anemarrhenae are raw material, according to the characteristic of medicine through pulverizing, soak, decoct, filter, concentrate, ethanol extraction, mix, technologies such as porphyrize are made, it is introduced that this curative effect of medication is excellent, but this medicine compatibility is more, sometimes be difficult to assort, and complicated process of preparation gives to apply to make troubles; Chinese invention patent CN1132608C, application number is 01113997.8, denomination of invention is: disclose a kind of Chinese medicine for the treatment of thromboangiitis obliterans in " a kind of Chinese medicine for the treatment of thromboangiitis obliterans ", it is by Radix Angelicae Sinensis, the Radix Paeoniae Alba, Semen Persicae, Flos Carthami, Radix Scrophulariae, Radix Salviae Miltiorrhizae, Flos Lonicerae, Fructus Forsythiae, Radix Ilicis Pubescentis, Rhizoma Smilacis Glabrae, Squama Manis, Hirudo, Scolopendra, 21 kinds of principal agents such as Eupolyphaga Seu Steleophaga and Rhizoma Coptidis, Cortex Phellodendri, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, 5 kinds of attached medicines of Rhizoma Zingiberis are pulverize together, incapsulate or become decoction to form with decocting, it is more that this Chinese medicine has compatibility equally, the shortcoming that is difficult to assort, and cost is higher, for vast rural area and remote mountain area patient, there is a kind of serious financial burden.Chinese invention patent CN1023968C, application number is 90106330.4, denomination of invention is: disclose a kind of preparation method for the treatment of the smoke of vasculitis disease in " preparation method of angitis fumigant ", but smoke has shortcomings such as complex manufacturing technology, use inconvenience.So, people still crave for have a kind of cost low, be convenient to take and medicine that therapeutic effect is better treated thromboangiitis obliterans comes out.
Three. summary of the invention:
The objective of the invention is: the medicine that a kind of advantages of simple of filling a prescription, clinical effectiveness treatment thromboangiitis obliterans remarkable, with low cost is provided.
Technical scheme of the present invention is: a kind of medicine for the treatment of thromboangiitis obliterans, containing with the weight portion is the following natural material medicine of unit, 10~30 parts of Radix Angelicae Sinensis, 5~15 parts of Ramulus Cinnamomi, 30~60 parts of the Radixs Astragali, 10~30 parts of Radix Ginsengs, 10~20 parts in Radix Rehmanniae Preparata.
The medicine of described treatment thromboangiitis obliterans, also containing with the weight portion is the following natural material medicine of unit, 30~60 parts of Flos Loniceraes, 20~50 parts of Radix Scrophulariaes, 10~20 parts of Radix Achyranthis Bidentataes.
The optimum ratio of the medicine of described treatment thromboangiitis obliterans is: 30 parts of Radix Angelicae Sinensis, 15 parts of Ramulus Cinnamomi, 30 parts of the Radixs Astragali, 20 parts of Radix Ginsengs, 20 parts in Radix Rehmanniae Preparata, 30 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 18 parts of Radix Achyranthis Bidentataes.
A kind of medicine for the treatment of thromboangiitis obliterans, containing with the weight portion is the following natural material medicine of unit, 15~25 parts of Radix Angelicae Sinensis, 6~10 parts of Ramulus Cinnamomi, 40~50 parts of the Radixs Astragali, 15~25 parts of Radix Ginsengs, 10~20 parts in Radix Rehmanniae Preparata.
The medicine of described treatment thromboangiitis obliterans, also containing with the weight portion is the following natural material medicine of unit, 40~50 parts of Flos Loniceraes, 30~40 parts of Radix Scrophulariaes, 10~20 parts of Radix Achyranthis Bidentataes.
The optimum ratio of the medicine of described treatment thromboangiitis obliterans is: 20 parts of Radix Angelicae Sinensis, 10 parts of Ramulus Cinnamomi, 40 parts of the Radixs Astragali, 15 parts of Radix Ginsengs, 15 parts in Radix Rehmanniae Preparata, 45 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 10 parts of Radix Achyranthis Bidentataes.
With described Radix Angelicae Sinensis, Radix Rehmanniae Preparata lyophilizing, remaining each component oven dry after grinding together, is crossed 100 mesh sieves, makes required pharmaceutical dosage form.
Described pharmaceutical dosage form is a powder, or is tablet, or is pill, or is granule, or is capsule.
Positive beneficial effect of the present invention is:
1. the medicine of treatment thromboangiitis obliterans of the present invention, based on motherland's Chinese medicine and pharmacy theory, in conjunction with clinical practice for many years, from motherland medicine treasure-house, filter out have heat-clearing and toxic substances removing, YIN nourishing removing heat from blood, activating blood circulation and dissipating blood stasis, dispelling cold by warming the meridian, benefiting qi and nourishing blood, recuperating depleted YANG are promoted blood circulation, the pure purification of tcm of removing the necrotic tissue and promoting granulation forms, effect with blood vessel dilating, thrombus, blood circulation promoting, the local blood supply state of change, and residence is attacked in mending, attacking and just not to be hindered, to mend and do not stop up, and can obviously improve the immunity of human body.
2. the medicine of treatment thromboangiitis obliterans of the present invention is a Chinese medicine preparation, need not decoct, can carry, and taking convenience, general patients with mild need not be in hospital, and can reduce patient's spending significantly, reduces medical expense.
3. the medicine of treatment thromboangiitis obliterans of the present invention, prescription is reasonable, and cost is low, and processing is simple, and clinical efficacy is obvious, is applicable to the thromboangiitis obliterans patient that each phase is dissimilar.
4. the medicine of treatment thromboangiitis obliterans of the present invention, when the patient with severe symptoms of treatment second phase, three phases, other ancillary drug that adds the inventor cooperates the acupoint injection therapy treatment, effective percentage reaches 100%, especially to the patient of obstinate disease, can cure without amputation, be subjected to the favorable comment of patient and family numbers of patients deeply.
In the medicine of treatment thromboangiitis obliterans of the present invention: the sweet temperature of Radix Angelicae Sinensis toil, benefiting blood and regulating blood circulation is the key medicine of temperature compensation liver blood; The hot temperature of Ramulus Cinnamomi, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the evil logical blood of cold relieving is capable, and two medicines share, and take a tonic or nourishing food to build up one's health with Wen Tong and execute, and can receive an effect of mending two and three warm four-ways, and pretending is that monarch drug uses.The sweet temperature of the Radix Astragali, strongly invigorating primordial QI, reinforcing body resistance, eliminating evil going out associated with useful temperature sun, the outer power of driving of enhancing with Ramulus Cinnamomi warming the meridian for promoting the flow of YANG QI, the diffusing exopathogen of dispelling; The Radix Ginseng sweet in the mouth, invigorating primordial QI is slaked thirst and help produce saliva; Radix Rehmanniae Preparata tepor, but YIN nourishing removing heat from blood, the kidney invigorating is quenched one's thirst, and three medicines are all ministerial drug." necrosis " disease, non-one day of onset and sending out, exopathogenic factor has the cold-evil to cause, and is interior because give birth in the fire-toxin, pyretic toxicity is pented up, and QI and blood is retarded by silt, and the venation obturation is obstructed, and Flos Lonicerae, Radix Scrophulariae have the effect of heat-clearing and toxic substances removing, two medicines share, and both clearing heat in QI system divided pathogenic heat, separate cold-damp heat-transformation poison again, pretend to be the adjuvant drug use.Radix Achyranthis Bidentatae is gentle, but invigorating the liver and kidney, bone and muscle strengthening, and eliminating blood stasis and inducing menstruation, conducting blood to flow downwards are with being messenger drug.
The medicine of treatment thromboangiitis obliterans of the present invention, mechanism according to the traditional Chinese medical science " stagnation of QI is stasis then; the capable then blood of gas is capable; the capable then sick spontaneous recovery of blood ", reach the purpose of repercussive with benefiting vital QI and blood, " necrosis " patient again, the endogenous cause of ill heart, liver, spleen, kidney four is dirty all empty, and the exopathogenic factor cold-evil is strongly fragrant for a long time, accumulates and heat-transformation or surfeit greasy and surfeit flavour, pungently process rich and cause life fire-toxin in, if only use Radix Angelicae Sinensis, Ramulus Cinnamomi, the Radix Astragali, Radix Ginseng probably has impairment of YIN dryness-transformation anxiety, admittedly add Radix Rehmanniae Preparata, to make the scorching of the Ramulus Cinnamomi and the Radix Astragali, the kidney invigorating void again Kidney-Yin, monarch, minister, assistant, make and share, the effect of the dehumidifying of invigorating blood circulation is not only arranged, and detoxifcation arranged, removing heat from blood is fruit, it is applicable to the thromboangiitis obliterans patient that each phase is dissimilar, and especially the patient of obstinate disease can cure without amputation, being subjected to patient's favorable comment deeply, is the medicine of present comparatively ideal treatment thromboangiitis obliterans.
5. the clinical efficacy situation is added up:
Case is selected: the hospital at inventor place accepts patient's 2997 examples of the thromboangiitis obliterans in more than 100 county of 19 provinces, cities and autonomous regions in the whole nation so far altogether for medical treatment from the eighties in last century, male's 2398 examples wherein, women's 599 examples, male, women patient's ratio is about 4: 1, and patient 1798 examples of age between 20~45 years old account for 60%, patient 300 examples of age between 45~65 years old, account for 10%, the patient of other age bracket accounts for 30%, and the most of patients course of disease is more than half a year.
Diagnostic classification:, generally the patient is divided into three kinds according to medical history, symptom, sign:
First phase claims ischemic stage again, and side lower limb are afraid of cold, and acra is numb, whiteness of skin, and amyotrophy, the shank of walking expands and aches, knots;
Second phase claims the dysfunction phase again, and the lower limb acrodynia continues, and intermittent claudication is obvious, and toes continue to turn cold, and palor is livid purple;
Three phases claimed the downright bad phase again, and local organization is seriously downright bad, i.e. " gangrene ", dorsal artery of foot is beaten and is weakened or disappear, severe pain unbearably, slough obviously comes off.
Above-mentioned 2997 routine patients, first phase patient 1939 examples, the second stage of patient's 875 examples, three phase patients, 183 examples.
Therapeutic Method: to being diagnosed as the patient of thromboangiitis obliterans, give the drug administration of treatment thromboangiitis obliterans of the present invention, twice on the one, one time 6~12 gram, warm boiled water, 30 days is a course of treatment, generally needs to treat 1~6 course of treatment, effect preferably be can reach, suffering, peppery, greasy food and Folium Camelliae sinensis and tobacco and wine avoided at period in a medicine.
Curative effect judging standard:
Recovery from illness: symptom thoroughly disappears, no sequel;
Produce effects: symptom disappears substantially, and lame slightly after the treatment, other is as the normal person;
Effectively: pain and other symptom are obviously alleviated, and just can fully recover after adding inventor's other medicines auxiliary treatment.
Therapeutic outcome:
Clinical manifestation Recovery from illness Produce effects Effectively
Symptom Total number of persons Number Ratio Number Ratio Number Ratio
First phase 1939 1642 84.68% 275 14.08% 22 1.13%
Second phase 875 697 79.66% 138 15.77% 40 4.57%
Three phases 183 124 67.76% 28 15.30% 31 16.94%
Amount to 2997 2463 82.18% 441 14.71% 93 3.11%
By above-mentioned clinical efficacy situation statistics as can be known: the medicine of treatment thromboangiitis obliterans of the present invention has very notable therapeutic effect.
Model case:
1. Liu, man, 38 years old, people from Huangchuan County, Henan, shop assistant, severe winter patient way walking far away in 1971, toes are endured cold, and sensation left side foot is little painful then, and the heavy summer in winter is light, do not draw attention as yet, to the autumn in 1980 because of paddling twice, pain increases the weight of, whenever cold weather then severe pain unbearably, though once still do not produce effects with the Drug therapy of tiger-bone medicated wine wind-damp dispelling and so on, heavier to winter nineteen eighty-two pain, the purple black flowing water of Ipsilateral toes, the shank atrophy that attenuates is walked with difficulty, in the hospitalize that came the inventor place May 6 then, it is thin to see patient's yellow complexion, red tongue is red, and six kinds of pulses is heavy fine puckery, falls YANG pulse disappearances (left side) the popliteal of beating and moves A and beat also fine, suffer from toe and be black, little swollen, sending out of laying one's hand on is cool, a small amount of sewage is oozed on the first limit, the homonymy skin of leg is grey thick, and fine hair comes off, amyotrophy, Western medicine diagnose is: thromboangiitis obliterans, tcm diagnosis is: necrosis (yang deficiency cold-condensing type).The medicine of treatment thromboangiitis obliterans of the present invention is taken in suggestion, twice, one time on the one 8 gram, and warm boiled water is after the course of treatment, trouble toe corruption takes off tissue regeneration promoting, and muscle is ruddy, and wound will be healed, continuous again medicine of obeying a course of treatment, spirit is good, and symptom disappears entirely, and freedom of movement returns working unit.
The week certain, man, 42 years old, Liuzhou city government functionary, the hospitalize that on March 14th, 1988 was come the inventor place, patient master states: left foot send out cool be afraid of to freeze, numb, sharp ache, night more very, must injection dolantin pain relieving, walking is walked lamely, because of pain and emotion gloomy, coronary heart disease is shown effect often, have previously surplus the smoking history 20 year, biped cold injury and left side foot fracture medical history arranged, and have a heart disease, old lower wall infraction.See patient's left foot skin and be kermesinus, skin temperature is ice-cold, and toes skin follows the string, and fine hair disappears, the first other skin ulceration wound surface of seeing 0.6 centimetre of a diameter in the 4th toe outside, a left side has a little faint yellow transudate, and the YANG pulse disappearance of beating is fallen on a left side, walking is walked lamely, and need lean on and turn, red tongue.White and thin fur, stringy pulse, lower extremity blood flow figure, instep, left side and each toe-end blood flow of the tip figure all are irregular f wave, and wave amplitude does not disappear; This case Western medicine diagnose is: thromboangiitis obliterans, tcm diagnosis is: deficiency of YIN cold coagulation blood vessels, the YIN-cold type necrosis due to venation numbness resistance is obstructed (deficiency of YIN tremble with fear Sheng type).The medicine of treatment thromboangiitis obliterans of the present invention is taken in suggestion, twice, one time on the one 10 gram, warm boiled water, after half course of treatment, left foot skin alternating temperature, colour of skin flushing, pain relief, coronary heart disease, angina pectoris are not reaccessed yet, after two courses of treatment, walking is normal, and left skin of foot is warm, does not have uncomfortable symptom, recovery from illness is left hospital, and follows up a case by regular visits to not recurrence in 5 years.
3. Lee, man, 20 years old, the peasant, slope, Guangshan County, Henan river village people, come to go to a doctor June 11 nineteen ninety-five, body is looked into: the biped toe palm is downright bad as charcoal, light night pain day is heavy, and left hallux toe, inferior skin of toe fester and sequestrum occurs, vola about 13 * 18cm that festers, ulcer is extended down to the about 6 * 5cm in the outside, instep, other cutaneous necrosis of the vola back of the body, the about 6 * 5cm of right vola ulcer, biped ulceration place sewage is smelly dirty; Pale complexion, the thin Mental fatigue of shape, irritated irritability, inappetence, dark tongue quality, thin fur, pulse condition is counted accurately; This case Western medicine diagnose is: thromboangiitis obliterans, tcm diagnosis is: necrosis (YIN-cold poison Sheng type).Take the medicine of treatment thromboangiitis obliterans of the present invention, surgery is treated with inventor's other medicines, behind the two weeks, it is red that the wound color is changeed, and pain obviously alleviates, and slough begins to come off, diet increases, and spirit takes a turn for the better, after two courses of treatment, except that downright bad toes came off, other wound surface all healed, and pain disappears, can walk, add and consolidate curative effect, drug withdrawal after half a year four courses of treatment, so far follow up a case by regular visits to, all are normal.
4. high certain, the man, 38 years old, the peasant, Huang Po people from outskirts of a town, Hubei, on February 26th, 1996 went to a doctor, patient master states: necrosis medical history 10 years, once repeatedly advised the two lower limb of its amputation, patient's refusal at several families large hospital.It is thin to see the empty shape of body, and shallow complexion, severe pain are gone down on one's knees and embraced foot unbearably, and it is without cease to moan, and cardiopalmus is insomnia, and body of the tongue is light red, white and thin fur, deep-rolling pulse; Looking into two ice-cold , popliteal of lower limb, shin arteries and veins can not stereognosis, and both feet are not except that the female toe in a left side comes off, all the other come off entirely, and the routed pus of wound is green, and is dripping more than, smelly dirty unpleasant, this case Western medicine diagnose is: thromboangiitis obliterans (downright bad phase of three phases), tcm diagnosis is: necrosis (yang deficiency of spleen and stomache).Take two courses of treatment of medicine of treatment thromboangiitis obliterans of the present invention, newly granulating grows, and the wound surface color and luster takes a turn for the better, and the drug withdrawal of fully recovering after half a year is followed up a case by regular visits to so far, all normal nothing recurrences.
5. Zhang, the man, 38 years old, the cadre, Xiangtan County, Hunan innings cadre, patient's medical history: suffer from vasculitis several years, because of participating in field labour, bump broken toes accidentally and cause, the trouble toe festers and suppurates, and pain is serious, lies awake all night; Look into patient left side purple of standard purity, the rotten muscle of meat loses, and falls YANG pulse disappearances of beating, and three-toed festers to middle joint, rotten exposed bone, and it is ice-cold to suffer from foot, and pulse condition sinks carefully unable, the tongue fur BOHUANG; The medicine of treatment thromboangiitis obliterans of the present invention is taken in suggestion, uses the inventor's other drug in addition, after half course of treatment, pain subtracts, and ulcer flowing water also takes a turn for the better, and spiritual appetite is good, after three courses of treatment, rotten bone takes off, wound healing, walking must crutch, spirit, diet, sleep are as usual, continue to take two courses of treatment, recovery from illness, symptom disappears entirely, does not have recurrence so far.
Four. the specific embodiment:
Embodiment one: a kind of medicine for the treatment of thromboangiitis obliterans, containing with the weight portion is the following natural material medicine of unit: 10 parts of Radix Angelicae Sinensis, 5 parts of Ramulus Cinnamomi, 30 parts of the Radixs Astragali, 10 parts of Radix Ginsengs, 10 parts in Radix Rehmanniae Preparata, 30 parts of Flos Loniceraes, 20 parts of Radix Scrophulariaes, 10 parts of Radix Achyranthis Bidentataes, Radix Angelicae Sinensis, Radix Rehmanniae Preparata lyophilizing with described weight portion, remaining each component oven dry after grinding together, is crossed 100 mesh sieves, make required pharmaceutical dosage form, patient one time 6~12 gram, ante cibum warm boiled water, twice of every day, 30 days is a course of treatment, avoids suffering, peppery, greasy food and Folium Camelliae sinensis and tobacco and wine at period in a medicine.
Embodiment two: the preparation of present embodiment medicine and the method for taking are with embodiment one, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 30 parts of Radix Angelicae Sinensis, 15 parts of Ramulus Cinnamomi, 60 parts of the Radixs Astragali, 30 parts of Radix Ginsengs, 20 parts in Radix Rehmanniae Preparata, 60 parts of Flos Loniceraes, 50 parts of Radix Scrophulariaes, 20 parts of Radix Achyranthis Bidentataes.
Embodiment three: the preparation of present embodiment medicine and the method for taking are with embodiment one, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 30 parts of Radix Angelicae Sinensis, 15 parts of Ramulus Cinnamomi, 30 parts of the Radixs Astragali, 20 parts of Radix Ginsengs, 20 parts in Radix Rehmanniae Preparata, 30 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 18 parts of Radix Achyranthis Bidentataes.
Embodiment four: the preparation of present embodiment medicine and the method for taking are with embodiment one, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 20 parts of Radix Angelicae Sinensis, 10 parts of Ramulus Cinnamomi, 40 parts of the Radixs Astragali, 20 parts of Radix Ginsengs, 15 parts in Radix Rehmanniae Preparata, 50 parts of Flos Loniceraes, 40 parts of Radix Scrophulariaes, 15 parts of Radix Achyranthis Bidentataes.
Embodiment five: the preparation of present embodiment medicine and the method for taking are with embodiment one, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 15 parts of Radix Angelicae Sinensis, 8 parts of Ramulus Cinnamomi, 50 parts of the Radixs Astragali, 15 parts of Radix Ginsengs, 13 parts in Radix Rehmanniae Preparata, 45 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 12 parts of Radix Achyranthis Bidentataes.
Embodiment six: the preparation of present embodiment medicine and the method for taking are with embodiment one, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 25 parts of Radix Angelicae Sinensis, 14 parts of Ramulus Cinnamomi, 45 parts of the Radixs Astragali, 25 parts of Radix Ginsengs, 17 parts in Radix Rehmanniae Preparata, 55 parts of Flos Loniceraes, 35 parts of Radix Scrophulariaes, 19 parts of Radix Achyranthis Bidentataes.
Embodiment seven: a kind of medicine for the treatment of thromboangiitis obliterans, containing with the weight portion is the following natural material medicine of unit: 15 parts of Radix Angelicae Sinensis, 6 parts of Ramulus Cinnamomi, 40 parts of the Radixs Astragali, 15 parts of Radix Ginsengs, 10 parts in Radix Rehmanniae Preparata, 40 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 10 parts of Radix Achyranthis Bidentataes, Radix Angelicae Sinensis, Radix Rehmanniae Preparata lyophilizing with described weight portion, remaining each component oven dry after grinding together, is crossed 100 mesh sieves, make required pharmaceutical dosage form, patient one time 6~12 gram, ante cibum warm boiled water, twice of every day, 30 days is a course of treatment, avoids suffering, peppery, greasy food and Folium Camelliae sinensis and tobacco and wine at period in a medicine.
Embodiment eight: the preparation of present embodiment medicine and the method for taking are with embodiment seven, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 25 parts of Radix Angelicae Sinensis, 10 parts of Ramulus Cinnamomi, 50 parts of the Radixs Astragali, 25 parts of Radix Ginsengs, 20 parts in Radix Rehmanniae Preparata, 50 parts of Flos Loniceraes, 45 parts of Radix Scrophulariaes, 20 parts of Radix Achyranthis Bidentataes.
Embodiment nine: the preparation of present embodiment medicine and the method for taking are with embodiment seven, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 20 parts of Radix Angelicae Sinensis, 10 parts of Ramulus Cinnamomi, 40 parts of the Radixs Astragali, 15 parts of Radix Ginsengs, 15 parts in Radix Rehmanniae Preparata, 45 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 10 parts of Radix Achyranthis Bidentataes.
Embodiment ten: the preparation of present embodiment medicine and the method for taking are with embodiment seven, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 22 parts of Radix Angelicae Sinensis, 8 parts of Ramulus Cinnamomi, 45 parts of the Radixs Astragali, 20 parts of Radix Ginsengs, 17 parts in Radix Rehmanniae Preparata, 50 parts of Flos Loniceraes, 35 parts of Radix Scrophulariaes, 15 parts of Radix Achyranthis Bidentataes.
Embodiment 11: the preparation of present embodiment medicine and the method for taking are with embodiment seven, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 17 parts of Radix Angelicae Sinensis, 7 parts of Ramulus Cinnamomi, 43 parts of the Radixs Astragali, 19 parts of Radix Ginsengs, 14 parts in Radix Rehmanniae Preparata, 46 parts of Flos Loniceraes, 31 parts of Radix Scrophulariaes, 12 parts of Radix Achyranthis Bidentataes.
Embodiment 12: the preparation of present embodiment medicine and the method for taking are with embodiment seven, something in common does not repeat, difference is: a kind of medicine for the treatment of thromboangiitis obliterans, and containing with the weight portion is the following natural material medicine of unit: 22 parts of Radix Angelicae Sinensis, 9 parts of Ramulus Cinnamomi, 49 parts of the Radixs Astragali, 21 parts of Radix Ginsengs, 19 parts in Radix Rehmanniae Preparata, 43 parts of Flos Loniceraes, 38 parts of Radix Scrophulariaes, 18 parts of Radix Achyranthis Bidentataes.

Claims (8)

1. medicine for the treatment of thromboangiitis obliterans, it is characterized in that: containing with the weight portion is the following natural material medicine of unit, 10~30 parts of Radix Angelicae Sinensis, 5~15 parts of Ramulus Cinnamomi, 30~60 parts of the Radixs Astragali, 10~30 parts of Radix Ginsengs, 10~20 parts in Radix Rehmanniae Preparata.
2. the medicine of treatment thromboangiitis obliterans according to claim 1 is characterized in that: also containing with the weight portion is the following natural material medicine of unit, 30~60 parts of Flos Loniceraes, 20~50 parts of Radix Scrophulariaes, 10~20 parts of Radix Achyranthis Bidentataes.
3. the medicine of treatment thromboangiitis obliterans according to claim 2 is characterized in that: contain 30 parts of Radix Angelicae Sinensis, 15 parts of Ramulus Cinnamomi, 30 parts of the Radixs Astragali, 20 parts of Radix Ginsengs, 20 parts in Radix Rehmanniae Preparata, 30 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 18 parts of Radix Achyranthis Bidentataes.
4. medicine for the treatment of thromboangiitis obliterans, it is characterized in that: containing with the weight portion is the following natural material medicine of unit, 15~25 parts of Radix Angelicae Sinensis, 6~10 parts of Ramulus Cinnamomi, 40~50 parts of the Radixs Astragali, 15~25 parts of Radix Ginsengs, 10~20 parts in Radix Rehmanniae Preparata.
5. the medicine of treatment thromboangiitis obliterans according to claim 4 is characterized in that: also containing with the weight portion is the following natural material medicine of unit, 40~50 parts of Flos Loniceraes, 30~40 parts of Radix Scrophulariaes, 10~20 parts of Radix Achyranthis Bidentataes.
6. the medicine of treatment thromboangiitis obliterans according to claim 5 is characterized in that: contain 20 parts of Radix Angelicae Sinensis, 10 parts of Ramulus Cinnamomi, 40 parts of the Radixs Astragali, 15 parts of Radix Ginsengs, 15 parts in Radix Rehmanniae Preparata, 45 parts of Flos Loniceraes, 30 parts of Radix Scrophulariaes, 10 parts of Radix Achyranthis Bidentataes.
7. according to the medicine of the described treatment thromboangiitis obliterans of the arbitrary claim of claim 1~6, it is characterized in that: with described Radix Angelicae Sinensis, Radix Rehmanniae Preparata lyophilizing, remaining each component oven dry after grinding together, is crossed 100 mesh sieves, makes required pharmaceutical dosage form.
8. the medicine of treatment thromboangiitis obliterans according to claim 7 is characterized in that: described pharmaceutical dosage form is a powder, or is tablet, or is pill, or is granule, or is capsule.
CNB2005100176777A 2005-06-14 2005-06-14 Medicine for treating rhomboembolia type angiitis Expired - Fee Related CN1299723C (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600239A (en) * 2012-04-27 2012-07-25 由丽萍 Medicament for treating thromboangitis obliterans and preparation method thereof
CN104784335A (en) * 2015-04-13 2015-07-22 梁晓 Traditional Chinese medicine composition for treating qi-blood deficiency type thromboangiitis obliterans
CN107334862A (en) * 2017-08-22 2017-11-10 徐州艾博生物科技有限公司 Medicament for treating thromboangitis obliterans and preparation method thereof
CN113456734A (en) * 2021-07-30 2021-10-01 张明之 Formula for treating thromboangiitis obliterans
CN115137767A (en) * 2022-08-09 2022-10-04 石家庄平安医院有限公司 A Chinese medicinal composition for treating ischemic angiitis caused by cold deficiency syndrome, and its preparation method
CN116966232A (en) * 2023-09-15 2023-10-31 上海市静安区中医医院 Traditional Chinese medicine composition for treating phlegm-heat accumulated lung syndrome community-acquired pneumonia and application thereof

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CN1060960C (en) * 1997-06-26 2001-01-24 周淑琴 Health-care wine with antisenility function
CN1113663C (en) * 2000-06-01 2003-07-09 钱金舟 Medicinal composition for curing protrusion of lumber intervertebral disc
CN1319586C (en) * 2002-12-16 2007-06-06 闫位国 Medicinal composition for treating brain apoplexy

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600239A (en) * 2012-04-27 2012-07-25 由丽萍 Medicament for treating thromboangitis obliterans and preparation method thereof
CN102600239B (en) * 2012-04-27 2014-02-05 由丽萍 Medicament for treating thromboangitis obliterans and preparation method thereof
CN104784335A (en) * 2015-04-13 2015-07-22 梁晓 Traditional Chinese medicine composition for treating qi-blood deficiency type thromboangiitis obliterans
CN107334862A (en) * 2017-08-22 2017-11-10 徐州艾博生物科技有限公司 Medicament for treating thromboangitis obliterans and preparation method thereof
CN113456734A (en) * 2021-07-30 2021-10-01 张明之 Formula for treating thromboangiitis obliterans
CN115137767A (en) * 2022-08-09 2022-10-04 石家庄平安医院有限公司 A Chinese medicinal composition for treating ischemic angiitis caused by cold deficiency syndrome, and its preparation method
CN115137767B (en) * 2022-08-09 2023-04-28 石家庄平安医院有限公司 Traditional Chinese medicine composition for treating ischemic vasculitis caused by cold deficiency syndrome and preparation method thereof
CN116966232A (en) * 2023-09-15 2023-10-31 上海市静安区中医医院 Traditional Chinese medicine composition for treating phlegm-heat accumulated lung syndrome community-acquired pneumonia and application thereof

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