CN1113663C - Medicinal composition for curing protrusion of lumber intervertebral disc - Google Patents

Abstract

The present invention discloses a medicinal composition for curing lumbar intervertebral disk protrusion, which is mainly prepared from prepared rhizome of rehmannia, Chinese yam, rhizoma alismatis, cortex eucommiae, morinda roots, medlar, pilos antlers, Herba Epimedii, angelica, liquorice, etc. The present invention has the advantages that total effective rate on lumbar disc herniation reaches 98.6%, the course of treatment is short, and the curing cost is low.

Description

A kind of pharmaceutical composition for the treatment of prolapse of lumbar intervertebral disc

The invention belongs to field of medicaments, be specifically related to a kind of pharmaceutical composition for the treatment of prolapse of lumbar intervertebral disc.

Prolapse of lumbar intervertebral disc (bulging) disease is comparatively common disease; Especially in the rural area, sickness rate is higher.Clinical manifestation is left side or right side or both sides flank pain; Since prolapse of lumbar intervertebral disc (bulging) compressing sciatic nerve, therefore, outside the patient is radiated to behind the thigh from buttocks simultaneously, the shank outside, position pain numbness such as sufficient lateral heel, instep; Generally speaking, adopt conventional treatments treatments such as massage, massage, traction, effect is not ideal, and operative treatment is costly; A lot of patients cause the paralysis bed, disability because treatment is untimely, not thorough; The most sex-linkage viability of male patient reduces; Frequent micturition or urinary incontinence have a strong impact on work and life.

Traditional Chinese medical theory thinks that " lumbar vertebra " is under the jurisdiction of kidney, and governor vessel follows in ridge, and the kidney generating marrow and dominating bone relies moistening of body fluid foster, QI and blood warm.Suffering from a deficiency of the kidney, then governor vessel is not solid, causes prolapse of lumbar intervertebral disc.Therefore, intend throwing warming and recuperating the kidney-YANG, the living marrow of enriching blood, invigorating QI to relieve exhaustion makes lumbar inter vertebral disc reduction, and the medicine of blood circulation promoting and blood stasis dispelling, dampness removing collateral dredging is dredged oppressed sciatic nerve, blood circulation depending on qi flow, all disease the knowing of pain numbness are moved back.

Purpose of the present invention is exactly a kind of short treating period of proposing according to Traditional Chinese medical theory, evident in efficacy, pharmaceutical composition that treatment waist that medical expense is low pushes away disc herniation.

Composition of this pharmaceutical composition and content (weight portion) are:

Radix Rehmanniae Preparata 20-30 Rhizoma Dioscoreae 20-30 Fructus Corni 10-20

Cortex Moutan 10-15 lets out in the pool (salt stir-fry) 20-30 Poria 15-24

Cortex Cinnamomi 10-15 Radix Aconiti Lateralis Preparata 10-15 Herba Cistanches 15-24

The Cortex Eucommiae (salt stir-fry) 10-20 Fructus Psoraleae (salt stir-fry) 10-20 Rhizoma Cibotii 10-20

Radix Morindae Officinalis 15-25 Fructus Lycii 20-30 Hippocampus 10-15

Solenognathus 10-15 Radix Notoginseng 10-15 Herba Epimedii 10-15

Cornu Cervi Pantotrichum 10-15 Korean Ginseng 20-30 Radix Astragali 20-30

Agkistrodon 1-2 bar Colla Plastri Testudinis 10-15 Colla cornus cervi 10-15

Cortex Acanthopancis 10-15 Ramulus Cinnamomi 10-15 Ligamentum cervi 20-30

Radix Angelicae Sinensis 10-15 Lignum Sappan 10-15 Radix Glycyrrhizae 10-15

In the above-mentioned composition, let out in Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutan, pool, Poria, Cortex Cinnamomi, Radix Aconiti Lateralis Preparata eight flavors are JINGUI SHENQI WAN controls kidney ancestral side, be " monarch " that " minister " share to strengthen the kidney invigorating effect with Herba Cistanches, the Cortex Eucommiae, Fructus Psoraleae, Fructus Lycii, Radix Morindae Officinalis.Cornu Cervi Pantotrichum, Colla cornus cervi are gone into the governor vessel kidney warming and yang invigorating; Korean Ginseng, Radix Astragali strongly invigorating primordial QI, yang invigorating takes off admittedly, is " assistant "; " make " with Hippocampus, Solenognathus, Radix Notoginseng, not only the kidney invigorating but also cure the wound, to reach lumbar inter vertebral disc reduction; Also being aided with Colla Plastri Testudinis in the side goes into the operation that conception vessel connects governor vessel and does not stop reducing swelling and alleviating pain, Cortex Acanthopancis, Ligamentum cervi, Rhizoma Cibotii, bone and muscle strengthening; Herba Epimedii, Agkistrodon, Radix Angelicae Sinensis, Lignum Sappan, Ramulus Cinnamomi, blood circulation promoting and blood stasis dispelling, the dampness removing collateral dredging, dispersing cold for relieving pain, to eliminate the numb all diseases of limbs pain, Radix Glycyrrhizae goes into 12 through coordinating the actions of various ingredients in a prescription.

Aforementioned pharmaceutical compositions can be prepared into acceptable forms on the pharmaceuticss such as medicated wine, oral liquid, tablet, pill, capsule, electuary according to clinical needs.

The method that aforementioned pharmaceutical compositions is prepared into medicated wine is as follows;

Measure above-mentioned Chinese crude drug by prescription, shred or grind and be coarse powder, place appropriate vessel, add medical material total amount 6-8 Chinese liquor doubly, flood 7, stir once every day, after weekly stirring once generally flood more than 30 days; Get supernatant, leave standstill clarification, filter promptly.

Function with cure mainly: temperature male wind-supplying kidney, bone and muscle strengthening, reducing swelling and alleviating pain, promoting blood circulation to remove obstruction in the collateral.Be used for prolapse of lumbar intervertebral disc.To sciatica, acute and chronic pathogenic wind-warm arthritis, anemofrigid-damp arthralgia, lumbar muscle strain, numb hand and foot is ached, and diseases such as impotence due to deficiency of the kidney also have certain auxiliary treatment effect.Usage and consumption: take 50-100ml at every turn, every day 2-3 time, ante cibum or clothes backs, just before going to bed also can, 30 days is a course of treatment.

Period in a medicine, diet Radix Raphani, radish cabbage, tea.

The inventor treated over one hundred routine prolapse of lumbar intervertebral disc from 1994 with homemade medicated wine, obtained positive effect, now was summarized as follows:

One, case is selected: select prolapse of lumbar intervertebral disc patient 75 examples at random, symptom before the treatment: (1) lumbago sciatica that occurs together, and straight lower limb is praised limited; (2) the other tenderness of vertebra is often with the sciatic nerve radiating pain; (3) muscular strength of sciatic nerve domination, reflection and perceptual transformation; (4) intraspinal pressure power or tensilely increase test can excite the reproduction of lumbago and skelalgia; (5) waist range of activity selectivity is obstructed, and patient's happiness is taked protectiveness and selected position.Wherein 1 routine X-ray film making shows the lumbar degenerative osteoarthrosis, showed different hyperosteogeny in one to the five joint l spine ap ﹠ lat, and see that bony spur forms; Medical concept point analysis therefrom, wherein 70 routine patients are with in various degree kidney deficiency; Male patient's 65 examples, female patient 10 examples, the oldest 81 years old, minimum 29 years old.

Two, treatment standard:

1. cure: conscious above-mentioned symptom disappears.

2. produce effects: conscious above-mentioned symptom disappears substantially.

3. invalid: as to compare before symptom and the treatment, do not have to change.

Three, Therapeutic Method: all patients all take the medicated wine of the present invention's preparation, every day 2-3 time, during meal or after meal, take before sleeping, 50-100ml at every turn.One month is a course of treatment, the shortest course of treatment, the longest 2 courses of treatment.

Four, therapeutic outcome:

Transference cure person 68 examples account for 90.6%; Symptom is disappearance person's 6 examples substantially, account for 8%, and invalid 1 example accounts for 1.4%, and total effective rate is 98.6%, and in the The above results, invalid 1 example because of the irritated drug withdrawal of patient's ethanol, is not used other dosage form instead.

Five, matched group: select 20 routine patients with lumbar disc herniation else and adopt massage, massage, traction and hyperosteogeny one obedient clever cream external application affected part in contrast.Therapeutic Method: massaged, massage once in every routine 1-2 days, drew once in 1-3 days, an obedient clever cream external application changed medicine in 2 days one time, and curative effect is passed judgment on the same with the treatment group.Therapeutic outcome: transference cure 4 examples account for 20%; Produce effects 8 examples account for 40%, and invalid 8 examples account for 40%, total effective rate 60%.

Two groups of cure rate comparison sheets:

The prepared medicated wine of the present invention is described in detail in detail below more in conjunction with the embodiments:

Embodiment 1: get Radix Rehmanniae Preparata 200g, Rhizoma Dioscoreae 250g, Fructus Corni 100g, Cortex Moutan 100g, 250g is let out in the processed with salt pool, Poria 200g, Cortex Cinnamomi 150g, Radix Aconiti Lateralis Preparata 100g, Herba Cistanches 150g, Cortex Eucommiae (processed with salt) 150g, processed with salt Fructus Psoraleae 150g, Rhizoma Cibotii 150g, Radix Morindae Officinalis 150g, Fructus Lycii 250g, Hippocampus 150g, Solenognathus 150g, Radix Notoginseng 100g, Herba Epimedii 100g, Cornu Cervi Pantotrichum 100g, Korean Ginseng 250g, Radix Astragali 200g, 10 of Agkistrodons, Colla Plastri Testudinis 100g, Colla cornus cervi 100g, Cortex Acanthopancis 100g, Ramulus Cinnamomi 150g, Ligamentum cervi 200g, Radix Angelicae Sinensis 100g, Lignum Sappan 100g, Radix Glycyrrhizae 100g, totally three ten distinguish the flavor of, chopping, place altar, add 30.0kg Chinese liquor, flooded 7, stir once every day, stir once weekly after one week, flooded 35 days, get supernatant, leave standstill clarification, to get final product after four layers of filtered through gauze.

Embodiment 2: get Radix Rehmanniae Preparata 300g, Rhizoma Dioscoreae 300g, Fructus Corni 200g, Cortex Moutan 150g, 200g is let out in the processed with salt pool, Poria 150g, Cortex Cinnamomi 100g, Radix Aconiti Lateralis Preparata 150g, Herba Cistanches 240g, Cortex Eucommiae (processed with salt) 200g, processed with salt Fructus Psoraleae 100g, Rhizoma Cibotii 100g, Radix Morindae Officinalis 200g, Fructus Lycii 200g, Hippocampus 100g, Solenognathus 100g, Radix Notoginseng 150g, Herba Epimedii 150g, Cornu Cervi Pantotrichum 150g, Korean Ginseng 200g, Radix Astragali 250g, 20 of Agkistrodons, Colla Plastri Testudinis 150g, Colla cornus cervi 150g, Cortex Acanthopancis 150g, Ramulus Cinnamomi 100g, Ligamentum cervi 300g, Radix Angelicae Sinensis 150g, Lignum Sappan 150g, Radix Glycyrrhizae 150g, totally three ten distinguish the flavor of, chopping, place altar, add 40kg Chinese liquor, flooded 7, stir once every day, stir once weekly after one week, flooded 35 days, and got supernatant; Leave standstill clarification, to get final product after four layers of filtered through gauze.

Embodiment 3: get Radix Rehmanniae Preparata 250g, Rhizoma Dioscoreae 200g, Fructus Corni 150g, Cortex Moutan 130g, 300g is let out in the processed with salt pool, Poria 240g, Cortex Cinnamomi 120g, Radix Aconiti Lateralis Preparata 130g, Herba Cistanches 200g, Cortex Eucommiae (processed with salt) 100g, processed with salt Fructus Psoraleae 200g, Rhizoma Cibotii 200g, Radix Morindae Officinalis 250g, Fructus Lycii 300g, Hippocampus 130g, Solenognathus 130g, Radix Notoginseng 130g, Herba Epimedii 130g, Cornu Cervi Pantotrichum 130g, Korean Ginseng 300g, Radix Astragali 300g, 10 of Agkistrodons, Colla Plastri Testudinis 130g, Colla cornus cervi 130g, Cortex Acanthopancis 130g, Ramulus Cinnamomi 130g, Ligamentum cervi 300g, Radix Angelicae Sinensis 130g, Lignum Sappan 130g, Radix Glycyrrhizae 130g, totally three ten distinguish the flavor of, chopping, place altar, add 36kg Chinese liquor, flooded 7, stir once every day, stir once weekly after one week, flooded 35 days, get supernatant, leave standstill clarification, to get final product after four layers of filtered through gauze.

Claims (1)

1. pharmaceutical composition for the treatment of prolapse of lumbar intervertebral disc, its raw material is formed and weight proportion is:

Radix Rehmanniae Preparata 20-30 Rhizoma Dioscoreae 20-30 Fructus Corni 10-20

Cortex Moutan 10-15 salt is fried Rhizoma Alismatis 20-30 Poria 15-24

Cortex Cinnamomi 10-15 Radix Aconiti Lateralis Preparata 10-15 Herba Cistanches 15-24

Cortex Eucommiae (parched with salt) 10-20 salt Fructus Psoraleae (parched) 10-20 Rhizoma Cibotii 10-20

Radix Morindae Officinalis 15-25 Fructus Lycii 20-30 Hippocampus 10-15

Solenognathus 10-15 Radix Notoginseng 10-15 Herba Epimedii 10-15

Cornu Cervi Pantotrichum 10-15 Korean Ginseng 20-30 Radix Astragali 20-30

Agkistrodon 1-2 bar Colla Plastri Testudinis 10-15 Colla cornus cervi 10-15

Cortex Acanthopancis 10-15 Ramulus Cinnamomi 10-15 Ligamentum cervi 20-30

Radix Angelicae Sinensis 10-15 Lignum Sappan 10-15 Radix Glycyrrhizae 10-15